Citations (50)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (3)
Marwa E. Elsherbiny & Dion R. Brocks. (2011) The ability of polycyclic aromatic hydrocarbons to alter physiological factors underlying drug disposition. Drug Metabolism Reviews 43:4, pages 457-475.
Read now
Read now
M. Ozkarsli, H. Sevim & A. Sen. (2008) In vivo effects of Urtica urens (dwarf nettle) on the expression of CYP1A in control and 3-methylcholanthrene-exposed rats. Xenobiotica 38:1, pages 48-61.
Read now
Read now
Hesham M. Korashy & Ayman O. S. El-Kadi. (2006) The Role of Aryl Hydrocarbon Receptor in the Pathogenesis of Cardiovascular Diseases. Drug Metabolism Reviews 38:3, pages 411-450.
Read now
Read now
Articles from other publishers (47)
Bo-Han Wang, Ling-Ling Tang, Xian-Hong Sun, Qian Zhang, Chun-Yang Liu, Xiao-Na Zhang, Ke-Yao Yu, Ying Yang, Jun Hu, Xiao-Lu Shi, Yue Wang & Li Liu. (2024) Qufeng Xuanbi Formula inhibited benzo[a]pyrene-induced aggravated asthma airway mucus secretion by AhR/ROS/ERK pathway. Journal of Ethnopharmacology 319, pages 117203.
Crossref
Crossref
Mi Jeong Heo, Ji Ho Suh, Sung Ho Lee, Kyle L. Poulsen, Yu A. An, Bhagavatula Moorthy, Sean M. Hartig, David D. Moore & Kang Ho Kim. (2023) Aryl hydrocarbon receptor maintains hepatic mitochondrial homeostasis in mice. Molecular Metabolism 72, pages 101717.
Crossref
Crossref
Maha Abdulla ALWAILI. (2023) Protective effects of lemongrass (Cymbopogon citratus STAPF) extract mediated mitochondrial fission and glucose uptake inhibition in SW1417. Food Science and Technology 43.
Crossref
Crossref
Min Luo, Dan Luo, Jie Liu, Huailing Wang, Xiaoyu Liu, Min Yang, Fangfang Tian, Suofu Qin & Yuying Li. (2022) Ameliorative effect of the probiotic peptide against benzo(α)pyrene-induced inflammatory damages in enterocytes. International Immunopharmacology 112, pages 109255.
Crossref
Crossref
Mariam Abdulaziz Alkhateeb, Wedad Refaiea Al-Otaibi, Qwait AlGabbani, Amena Ali Alsakran, Alaa Ahmed Alnafjan, Amani Mohammed Alotaibi & Wedad Saeed Al-Qahtani. (2021) Low-temperature extracts of Purple blossoms of basil (Ocimum basilicum L.) intervened mitochondrial translocation contributes prompted apoptosis in human breast cancer cells. Biological Research 54:1.
Crossref
Crossref
Yujie Huang, Jie Zhang, Yizhou Tao, Cheng Ji, Stanley Aniagu, Yan Jiang & Tao Chen. (2021) AHR/ROS-mediated mitochondria apoptosis contributes to benzo[a]pyrene-induced heart defects and the protective effects of resveratrol. Toxicology 462, pages 152965.
Crossref
Crossref
Vladimir Kodzhahinchev, Kamran Shekh, Lynn P. Weber & Som Niyogi. (2021) Interactive effects of cadmium and Benzo[a]pyrene in adult zebrafish (Danio rerio) during short-term aqueous co-exposure. Environmental Pollution 272, pages 116027.
Crossref
Crossref
Stephen G. Giteru, Belinda Cridge, Indrawati Oey, Azam Ali & Eric Altermann. (2020) In-vitro degradation and toxicological assessment of pulsed electric fields crosslinked zein-chitosan-poly(vinyl alcohol) biopolymeric films. Food and Chemical Toxicology 135, pages 111048.
Crossref
Crossref
Perrine J. Martin, Amélie Héliot, Gauthier Trémolet, Yann Landkocz, Dorothée Dewaele, Fabrice Cazier, Frédéric Ledoux & Dominique Courcot. (2019) Cellular response and extracellular vesicles characterization of human macrophages exposed to fine atmospheric particulate matter. Environmental Pollution 254, pages 112933.
Crossref
Crossref
Tetyana Kobets & Gary M. Williams. (2019) Review of the evidence for thresholds for DNA-Reactive and epigenetic experimental chemical carcinogens. Chemico-Biological Interactions 301, pages 88-111.
Crossref
Crossref
Takumi Ishida & Shinji Takechi. (2019) β-Naphthoflavone, an exogenous ligand of aryl hydrocarbon receptor, disrupts zinc homeostasis in human hepatoma HepG2 cells. The Journal of Toxicological Sciences 44:10, pages 711-720.
Crossref
Crossref
Arnaud Tête, Isabelle Gallais, Muhammad Imran, Martine Chevanne, Marie Liamin, Lydie Sparfel, Simon Bucher, Agnès Burel, Normand Podechard, Brice M.R. Appenzeller, Bernard Fromenty, Nathalie Grova, Odile Sergent & Dominique Lagadic-Gossmann. (2018) Mechanisms involved in the death of steatotic WIF-B9 hepatocytes co-exposed to benzo[a]pyrene and ethanol: a possible key role for xenobiotic metabolism and nitric oxide. Free Radical Biology and Medicine 129, pages 323-337.
Crossref
Crossref
Mariko Yokota, Shoichi Yahagi & Hitoshi Masaki. (2018) Ethyl 2,4-dicarboethoxy pantothenate, a derivative of pantothenic acid, prevents cellular damage initiated by environmental pollutants through Nrf2 activation. Journal of Dermatological Science 92:2, pages 162-171.
Crossref
Crossref
Zaid Maayah, Ti Zhang, Marcus Forrest, Samaa Alrushaid, Michael Doschak, Neal Davies & Ayman El-Kadi. (2018) DOX-Vit D, a Novel Doxorubicin Delivery Approach, Inhibits Human Osteosarcoma Cell Proliferation by Inducing Apoptosis While Inhibiting Akt and mTOR Signaling Pathways. Pharmaceutics 10:3, pages 144.
Crossref
Crossref
Mika Murai, Kazuhiko Yamamura, Akiko Hashimoto-Hachiya, Gaku Tsuji, Masutaka Furue & Chikage Mitoma. (2018) Tryptophan photo-product FICZ upregulates AHR/MEK/ERK-mediated MMP1 expression: Implications in anti-fibrotic phototherapy. Journal of Dermatological Science 91:1, pages 97-103.
Crossref
Crossref
Bora Yim, Hokyun Kim, Jisoo Kim, Haeyeon Kim, Eun-Ji Won & Young-Mi Lee. (2017) Identification and molecular characterization of cytochrome P450 (CYP450) family genes in the marine ciliate Euplotes crassus : The effect of benzo[ a ]pyrene and beta-naphthoflavone. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 196, pages 71-80.
Crossref
Crossref
Jae Min Choi, Eunae Cho, Benel Lee, Daham Jeong, Youngjin Choi, Jae-Hyuk Yu & Seunho Jung. (2016) Enhancing bio-availability of β-naphthoflavone by supramolecular complexation with 6,6′-thiobis(methylene)-β-cyclodextrin dimer. Carbohydrate Polymers 151, pages 40-50.
Crossref
Crossref
Sheng-Yao Hsu, Je-Wen Liou, Tsung-Lin Cheng, Shih-Yi Peng, Chi-Chen Lin, Yuan-Yuan Chu, Wei-Cheng Luo, Zheng-Kai Huang & Shinn-Jong Jiang. (2015) beta-Naphthoflavone protects from peritonitis by reducing TNF-alpha-induced endothelial cell activation. Pharmacological Research 102, pages 192-199.
Crossref
Crossref
Jae-Sung Rhee, Young-Mi Lee, Bo-Mi Kim, Kenneth Mei Yee Leung, Il-Chan Kim, Joung Han Yim & Jae-Seong Lee. (2015)
β
-Naphthoflavone induces oxidative stress in the intertidal copepod,
Tigriopus japonicus
. Environmental Toxicology 30:3, pages 332-342.
Crossref
Crossref
Zhouwei Wu, Hiroshi Uchi, Saori Morino-Koga, Akiko Nakamura-Satomura, Kazuyo Kita, Weimin Shi & Masutaka Furue. (2014) Z-Ligustilide inhibits benzo(a)pyrene-induced CYP1A1 upregulation in cultured human keratinocytes via ROS-dependent Nrf2 activation. Experimental Dermatology 23:4, pages 260-265.
Crossref
Crossref
Osama H. Elshenawy, Anwar Anwar-Mohamed, Ghada Abdelhamid & Ayman O.S. El-Kadi. (2013) Murine atrial HL-1 cell line is a reliable model to study drug metabolizing enzymes in the heart. Vascular Pharmacology 58:4, pages 326-333.
Crossref
Crossref
Seong Il Jeong, Seung Eun Lee, Hana Yang, Cheung-Seog Park, Jeong-Je Cho & Yong Seek Park. (2012) MicroRNA microarray analysis of human umbilical vein endothelial cells exposed to benzo(a)pyrene. BioChip Journal 6:2, pages 191-196.
Crossref
Crossref
Hesham M. Korashy, Zaid H. Maayah, Adel R. Abd-Allah, Ayman O. S. El-Kadi & Abdulqader A. Alhaider. (2012) Camel Milk Triggers Apoptotic Signaling Pathways in Human Hepatoma HepG2 and Breast Cancer MCF7 Cell Lines through Transcriptional Mechanism. Journal of Biomedicine and Biotechnology 2012, pages 1-9.
Crossref
Crossref
Hesham M. Korashy & Ayman O.S. El-Kadi. (2012) Transcriptional and posttranslational mechanisms modulating the expression of the cytochrome P450 1A1 gene by lead in HepG2 cells: A role of heme oxygenase. Toxicology 291:1-3, pages 113-121.
Crossref
Crossref
Guangtao Yang, Ying Jiang, Kaimin Rao, Xi Chen, Qian Wang, Ailin Liu, Wei Xiong & Jing Yuan. (2011) Mitochondrial dysfunction and transactivation of p53-dependent apoptotic genes in BaP-treated human fetal lung fibroblasts. Human & Experimental Toxicology 30:12, pages 1904-1913.
Crossref
Crossref
Anna Eckers, Elisabeth Sauerbier, Anwar Anwar-Mohamed, Ingrit Hamann, Charlotte Esser, Peter Schroeder, Ayman O.S. El-Kadi & Lars-Oliver Klotz. (2011) Detection of a functional xenobiotic response element in a widely employed FoxO-responsive reporter construct. Archives of Biochemistry and Biophysics 516:2, pages 138-145.
Crossref
Crossref
Ying Jiang, Xue Zhou, Xi Chen, Guangtao Yang, Qian Wang, Kaimin Rao, Wei Xiong & Jing Yuan. (2011) Benzo(a)pyrene-induced mitochondrial dysfunction and cell death in p53-null Hep3B cells. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 726:1, pages 75-83.
Crossref
Crossref
Antonietta Melchini, Stefania Catania, Rossana Stancanelli, Silvana Tommasini & Chiara Costa. (2011) Interaction of a functionalized complex of the flavonoid hesperetin with the AhR pathway and CYP1A1 expression: involvement in its protective effects against benzo[a]pyrene-induced oxidative stress in human skin. Cell Biology and Toxicology 27:5, pages 371-379.
Crossref
Crossref
Lindsey A. Van Tiem & Richard T. Di Giulio. (2011) AHR2 knockdown prevents PAH-mediated cardiac toxicity and XRE- and ARE-associated gene induction in zebrafish (Danio rerio). Toxicology and Applied Pharmacology 254:3, pages 280-287.
Crossref
Crossref
C.-H. Pan, T.-S. Shih, C.-J. Chen, J.-H. Hsu, S.-C. Wang, C.-P. Huang, C.-T. Kuo, K.-Y. Wu, H. Hu & C.-C. Chan. (2010) Reduction of cooking oil fume exposure following an engineering intervention in Chinese restaurants. Occupational and Environmental Medicine 68:1, pages 10-15.
Crossref
Crossref
C. Costa, S. Catania, R. De Pasquale, R. Stancanelli, G.M. Scribano & A. Melchini. (2010) Exposure of human skin to benzo[a]pyrene: Role of CYP1A1 and aryl hydrocarbon receptor in oxidative stress generation. Toxicology 271:3, pages 83-86.
Crossref
Crossref
Beshay N.M. Zordoky & Ayman O.S. El-Kadi. (2010) 2,3,7,8-Tetrachlorodibenzo-p-dioxin and β-naphthoflavone induce cellular hypertrophy in H9c2 cells by an aryl hydrocarbon receptor-dependant mechanism. Toxicology in Vitro 24:3, pages 863-871.
Crossref
Crossref
Lewis Zhichang Shi & Charles J. Czuprynski. (2009) Beta-naphthoflavone causes an AhR-independent inhibition of invasion and intracellular multiplication of Listeria monocytogenes in murine hepatocytes. Microbial Pathogenesis 47:5, pages 258-266.
Crossref
Crossref
Evelyn Lamy, Julia Schröder, Stefanie Paulus, Peter Brenk, Thorsten Stahl & Volker Mersch-Sundermann. (2008) Antigenotoxic properties of Eruca sativa (rocket plant), erucin and erysolin in human hepatoma (HepG2) cells towards benzo(a)pyrene and their mode of action. Food and Chemical Toxicology 46:7, pages 2415-2421.
Crossref
Crossref
Yasuaki Dewa, Jihei Nishimura, Masako Muguruma, Meilan Jin, Yukie Saegusa, Toshiya Okamura, Masako Tasaki, Takashi Umemura & Kunitoshi Mitsumori. (2008) β-Naphthoflavone enhances oxidative stress responses and the induction of preneoplastic lesions in a diethylnitrosamine-initiated hepatocarcinogenesis model in partially hepatectomized rats. Toxicology 244:2-3, pages 179-189.
Crossref
Crossref
Negar Gharavi & Ayman O.S. El‐Kadi. (2007) Role of Nitric Oxide in Downregulation of Cytochrome P450 1a1 and NADPH: Quinone Oxidoreductase 1 by Tumor Necrosis Factor‐α and Lipopolysaccharide. Journal of Pharmaceutical Sciences 96:10, pages 2795-2807.
Crossref
Crossref
Masanori Kitamura & Ayumi Kasai. (2007) Cigarette smoke as a trigger for the dioxin receptor-mediated signaling pathway. Cancer Letters 252:2, pages 184-194.
Crossref
Crossref
T. Lin & M.S. Yang. (2007) Benzo[a]pyrene-induced elevation of GSH level protects against oxidative stress and enhances xenobiotic detoxification in human HepG2 cells. Toxicology 235:1-2, pages 1-10.
Crossref
Crossref
Anwar Anwar-Mohamed & Ayman O.S. El-Kadi. (2007) Induction of cytochrome P450 1a1 by the food flavoring agent, maltol. Toxicology in Vitro 21:4, pages 685-690.
Crossref
Crossref
Amit Chaudhary, Tibor Pechan & Kristine L. Willett. (2007) Differential protein expression of peroxiredoxin I and II by benzo(a)pyrene and quercetin treatment in 22Rv1 and PrEC prostate cell lines. Toxicology and Applied Pharmacology 220:2, pages 197-210.
Crossref
Crossref
Yusuke Yokouchi, Masako Muguruma, Mitsuyoshi Moto, Miwa Takahashi, Meilan Jin, Yusuke Kenmochi, Taichi Kohno, Yasuaki Dewa & Kunitoshi Mitsumori. (2007) Molecular Analysis on the Possible Mechanism of .BETA.-Naphthoflavone-Induced Hepatocarcinogenesis in Rats. Journal of Toxicologic Pathology 20:1, pages 29-37.
Crossref
Crossref
Volker Mersch-Sundermann, Theeshan Bahorun, Thorsten Stahl, Vidushi S. Neergheen, Muhammad A. Soobrattee, Robert Wohlfarth, Rosa Sobel, Hubertus E. Brunn, Tim Schmeiser, Evelyn Lamy & Okezie I. Aruoma. (2006) Assessment of the DNA damaging potency and chemopreventive effects towards BaP-induced genotoxicity in human derived cells by Monimiastrum globosum, an endemic Mauritian plant. Toxicology in Vitro 20:8, pages 1427-1434.
Crossref
Crossref
Morgane Gorria, Laurence Huc, Odile Sergent, Amélie Rebillard, François Gaboriau, Marie-Thérèse Dimanche-Boitrel & Dominique Lagadic-Gossmann. (2006) Protective effect of monosialoganglioside GM1 against chemically induced apoptosis through targeting of mitochondrial function and iron transport. Biochemical Pharmacology 72:10, pages 1343-1353.
Crossref
Crossref
Hesham M. Korashy & Ayman O.S. El-Kadi. (2006) The role of aryl hydrocarbon receptor and the reactive oxygen species in the modulation of glutathione transferase by heavy metals in murine hepatoma cell lines. Chemico-Biological Interactions 162:3, pages 237-248.
Crossref
Crossref
Shur-Hueih Cherng, Shih-Lan Hsu, Jia-Ling Yang, Chang-Tze Ricky Yu & Huei Lee. (2006) Suppressive effect of 1-nitropyrene on benzo[a]pyrene-induced CYP1A1 protein expression in HepG2 cells. Toxicology Letters 161:3, pages 236-243.
Crossref
Crossref
Hesham M. Korashy & Ayman O. S. El-Kadi. (2005) Regulatory Mechanisms Modulating the Expression of Cytochrome P450 1A1 Gene by Heavy Metals. Toxicological Sciences 88:1, pages 39-51.
Crossref
Crossref
Garth H. Oakes & John R. Bend. (2005) Early steps in bilirubin-mediated apoptosis in murine hepatoma (Hepa 1c1c7) cells are characterized by aryl hydrocarbon receptor-independent oxidative stress and activation of the mitochondrial pathway. Journal of Biochemical and Molecular Toxicology 19:4, pages 244-255.
Crossref
Crossref