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Research Article

Glucuronidation of the Green Tea Catechins, (-)-epigallocatechin-3-gallate and (-)-epicatechin-3-gallate, by Rat Hepatic and Intestinal Microsomes

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Pages 1025-1031 | Published online: 07 Jul 2009

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Guangyi Yang, Shufan Ge, Rashim Singh, Sumit Basu, Katherine Shatzer, Ming Zen, Jiong Liu, Yifan Tu, Chenning Zhang, Jinbao Wei, Jian Shi, Lijun Zhu, Zhongqiu Liu, Yuan Wang, Song Gao & Ming Hu. (2017) Glucuronidation: driving factors and their impact on glucuronide disposition. Drug Metabolism Reviews 49:2, pages 105-138.
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Ons Ousji & Lekha Sleno. (2022) Structural Elucidation of Novel Stable and Reactive Metabolites of Green Tea Catechins and Alkyl Gallates by LC-MS/MS. Antioxidants 11:9, pages 1635.
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Sarah Schmitt, Sebastian Tratzka, Andreas Schieber & Maike Passon. (2019) Hemisynthesis of Anthocyanin Phase II Metabolites by Porcine Liver Enzymes. Journal of Agricultural and Food Chemistry 67:22, pages 6177-6189.
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Maike Passon. 2019. Bioactive Molecules in Food. Bioactive Molecules in Food 1929 1958 .
Maged Younes, Peter Aggett, Fernando Aguilar, Riccardo Crebelli, Birgit Dusemund, Metka Filipič, Maria Jose Frutos, Pierre Galtier, David Gott, Ursula Gundert‐Remy, Claude Lambré, Jean‐Charles Leblanc, Inger Therese Lillegaard, Peter Moldeus, Alicja Mortensen, Agneta Oskarsson, Ivan Stankovic, Ine Waalkens‐Berendsen, Rudolf Antonius Woutersen, Raul J Andrade, Cristina Fortes, Pasquale Mosesso, Patrizia Restani, Davide Arcella, Fabiola Pizzo, Camilla Smeraldi & Matthew Wright. (2018) Scientific opinion on the safety of green tea catechins. EFSA Journal 16:4.
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Maike Passon. 2017. Sweeteners. Sweeteners 1 30 .
Alexandru Filippi, Oana-Alina Ciolac, Constanța Ganea & Maria-Magdalena Mocanu. (2017) ErbB Proteins as Molecular Target of Dietary Phytochemicals in Malignant Diseases. Journal of Oncology 2017, pages 1-20.
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Liang Zhang, Yijun Wang, Daxiang Li, Chi-Tang Ho, Junsong Li & Xiaochun Wan. (2016) The absorption, distribution, metabolism and excretion of procyanidins. Food & Function 7:3, pages 1273-1281.
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Sebastian Rzeppa, Katharina Bittner, Susanne Döll, Sven Dänicke & Hans‐Ulrich Humpf. (2012) Urinary excretion and metabolism of procyanidins in pigs. Molecular Nutrition & Food Research 56:4, pages 653-665.
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Suraj P. Shrestha, John A. Thompson, Michael F. Wempe, Mallikarjuna Gu, Rajesh Agarwal & Chapla Agarwal. (2011) Glucuronidation and Methylation of Procyanidin Dimers B2 and 3,3″-Di-O-Galloyl-B2 and Corresponding Monomers Epicatechin and 3-O-Galloyl-Epicatechin in Mouse Liver. Pharmaceutical Research 29:3, pages 856-865.
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Young Hee Choi, Young-Won Chin & Yoon Gyoon Kim. (2011) Herb-drug interactions: Focus on metabolic enzymes and transporters. Archives of Pharmacal Research 34:11, pages 1843-1863.
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Baojian Wu, Kaustubh Kulkarni, Sumit Basu, Shuxing Zhang & Ming Hu. (2011) First-Pass Metabolism via UDP-Glucuronosyltransferase: a Barrier to Oral Bioavailability of Phenolics. Journal of Pharmaceutical Sciences 100:9, pages 3655-3681.
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Shengmin Sang, Joshua D. Lambert, Chi-Tang Ho & Chung S. Yang. (2011) The chemistry and biotransformation of tea constituents. Pharmacological Research 64:2, pages 87-99.
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Anna Castell-Auví, M. José Motilva, Alba Macià, Helena Torrell, Cinta Bladé, Montserrat Pinent, Lluís Arola & Anna Ardévol. (2010) Organotypic co-culture system to study plant extract bioactivity on hepatocytes. Food Chemistry 122:3, pages 775-781.
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Angélique Stalmach, William Mullen, Heike Steiling, Gary Williamson, Michael E. J. Lean & Alan Crozier. (2010) Absorption, metabolism, and excretion of green tea flavan‐3‐ols in humans with an ileostomy. Molecular Nutrition & Food Research 54:3, pages 323-334.
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Joshua D Lambert, Dou Hwan Kim, Ruijin Zheng & Chung S Yang. (2006) Transdermal delivery of (-)-epigallocatechin-3-gallate, a green tea polyphenol, in mice. Journal of Pharmacy and Pharmacology 58:5, pages 599-604.
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Iva Fernandes, Joana Azevedo, Ana Faria, Conceição Calhau, Victor de Freitas & Nuno Mateus. (2008) Enzymatic Hemisynthesis of Metabolites and Conjugates of Anthocyanins. Journal of Agricultural and Food Chemistry 57:2, pages 735-745.
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P.T. Devika & P. Stanely Mainzen Prince. (2008) (−)Epigallocatechin-gallate (EGCG) prevents mitochondrial damage in isoproterenol-induced cardiac toxicity in albino Wistar rats: A transmission electron microscopic and in vitro study. Pharmacological Research 57:5, pages 351-357.
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Gary Williamson, Isabelle Aeberli, Laurence Miguet, Ziding Zhang, M.-Belen Sanchez, Vanessa Crespy, Denis Barron, Paul Needs, Paul A. Kroon, H. Glavinas, Peter Krajcsi & Martin Grigorov. (2007) Interaction of Positional Isomers of Quercetin Glucuronides with the Transporter ABCC2 (cMOAT, MRP2). Drug Metabolism and Disposition 35:8, pages 1262-1268.
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Jie Xing, Chunfeng Xie & Hongxiang Lou. (2007) Recent applications of liquid chromatography–mass spectrometry in natural products bioanalysis. Journal of Pharmaceutical and Biomedical Analysis 44:2, pages 368-378.
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Michel Vignes, Tangui Maurice, Fabien Lanté, Magali Nedjar, Karen Thethi, Janique Guiramand & Max Récasens. (2006) Anxiolytic properties of green tea polyphenol (−)-epigallocatechin gallate (EGCG). Brain Research 1110:1, pages 102-115.
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