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Original

Oxygen therapy at low flow causes oxidative stress in chronic obstructive pulmonary disease: Prevention by N-acetyl cysteine

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Pages 1111-1118 | Published online: 07 Jul 2009

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Josefin Sundh, Zainab Ahmadi & Magnus Ekström. (2018) Daily duration of long-term oxygen therapy and risk of hospitalization in oxygen-dependent COPD patients. International Journal of Chronic Obstructive Pulmonary Disease 13, pages 2623-2628.
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Yanfei Shen, Wanru Cai, Shu Lei & Zhongheng Zhang. (2014) Effect of High/Low Dose N-Acetylcysteine on Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis. COPD: Journal of Chronic Obstructive Pulmonary Disease 11:3, pages 351-358.
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Stephney Whillier, Julia E. Raftos, Bogdan Chapman & Philip W. Kuchel. (2009) Role of N-acetylcysteine and cystine in glutathione synthesis in human erythrocytes. Redox Report 14:3, pages 115-124.
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Slobodan JankovićM.M., Semir Mehović, Edin Begić, Naida Omerović, Ana Antanasković, Radiša Vojinović & Milica Jovanović. (2023) Acute toxicity threshold of normobaric oxygen therapy: Systematic review. Galenika Medical Journal 2:5, pages 7-13.
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Yanfei Shen, Weizhe Ru, Xinmei Huang, Shangzhong Chen, Jing Yan, Zhouxin Yang & Guolong Cai. (2021) Impact of chronic respiratory diseases on re-intubation rate in critically ill patients: a cohort study. Scientific Reports 11:1.
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Salvatore Sotgia, Panagiotis Paliogiannis, Elisabetta Sotgiu, Sabrina Mellino, Elisabetta Zinellu, Alessandro G. Fois, Pietro Pirina, Ciriaco Carru, Arduino A. Mangoni & Angelo Zinellu. (2020) Systematic Review and Meta-Analysis of the Blood Glutathione Redox State in Chronic Obstructive Pulmonary Disease. Antioxidants 9:11, pages 1146.
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Yet H. Khor, David J.F. Smith, Kerri A. Johannson & Elisabetta Renzoni. (2020) Oxygen for interstitial lung diseases. Current Opinion in Pulmonary Medicine 26:5, pages 464-469.
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Josefin Sundh, Anna Bornefalk-Hermansson, Zainab Ahmadi, Anders Blomberg, Christer Janson, David C. Currow, Christine F. McDonald, Nikki McCaffrey & Magnus Ekström. (2019) REgistry-based randomized controlled trial of treatment and Duration and mortality in long-term OXygen therapy (REDOX) study protocol. BMC Pulmonary Medicine 19:1.
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Yet H. Khor, Elisabetta A. Renzoni, Dina Visca, Christine F. McDonald & Nicole S. L. Goh. (2019) Oxygen therapy in COPD and interstitial lung disease: navigating the knowns and unknowns. ERJ Open Research 5:3, pages 00118-2019.
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Luigino Calzetta, Paola Rogliani, Francesco Facciolo, Barbara Rinaldi, Mario Cazzola & Maria Gabriella Matera. (2018) N-Acetylcysteine protects human bronchi by modulating the release of neurokinin A in an ex vivo model of COPD exacerbation. Biomedicine & Pharmacotherapy 103, pages 1-8.
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Alfonso M. Lechuga-Sancho, David Gallego-Andujar, Pablo Ruiz-Ocaña, Francisco M. Visiedo, Ana Saez-Benito, Mónica Schwarz, Carmen Segundo & Rosa M. Mateos. (2018) Obesity induced alterations in redox homeostasis and oxidative stress are present from an early age. PLOS ONE 13:1, pages e0191547.
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Leona M. Dowman, Christine F. McDonald, Steven Bozinovski, Ross Vlahos, Rebecca Gillies, Dodie Pouniotis, Catherine J. Hill, Nicole S.L. Goh & Anne E Holland. (2017) Greater endurance capacity and improved dyspnoea with acute oxygen supplementation in idiopathic pulmonary fibrosis patients without resting hypoxaemia. Respirology 22:5, pages 957-964.
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Zainab Ahmadi, Josefin Sundh, Anna Bornefalk-Hermansson & Magnus Ekström. (2016) Long-Term Oxygen Therapy 24 vs 15 h/day and Mortality in Chronic Obstructive Pulmonary Disease. PLOS ONE 11:9, pages e0163293.
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Vincent J. Kopp & Joseph M. Stavas. (2016) POINT: Does Low-Dose Oxygen Expose Patients With COPD to More Radiation-Like Risks Than Patients Without COPD? Yes. Chest 149:2, pages 303-306.
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Idolo Tedesco, Virginia Carbone, Carmela Spagnuolo, Paola Minasi & Gian Luigi Russo. (2015) Identification and Quantification of Flavonoids from Two Southern Italian Cultivars of Allium cepa L., Tropea (Red Onion) and Montoro (Copper Onion), and Their Capacity to Protect Human Erythrocytes from Oxidative Stress . Journal of Agricultural and Food Chemistry 63:21, pages 5229-5238.
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Francisco Ortega Ruiz, Salvador Díaz Lobato, Juan Bautista Galdiz Iturri, Francisco García Rio, Rosa Güell Rous, Fátima Morante Velez, Luis Puente Maestu & Julia Tàrrega Camarasa. (2014) Oxigenoterapia continua domiciliaria. Archivos de Bronconeumología 50:5, pages 185-200.
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Francisco Ortega Ruiz, Salvador Díaz Lobato, Juan Bautista Galdiz Iturri, Francisco García Rio, Rosa Güell Rous, Fátima Morante Velez, Luis Puente Maestu & Julia Tàrrega Camarasa. (2014) Continuous Home Oxygen Therapy. Archivos de Bronconeumología (English Edition) 50:5, pages 185-200.
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Poornima Gopal, Erica P. A. Rutten, Mieke A. Dentener, Emiel F. M. Wouters & Niki L. Reynaert. (2012) Decreased plasma sRAGE levels in COPD: influence of oxygen therapy. European Journal of Clinical Investigation 42:8, pages 807-814.
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Anne M. FitzpatrickDean P. JonesLou Ann S. Brown. (2012) Glutathione Redox Control of Asthma: From Molecular Mechanisms to Therapeutic Opportunities. Antioxidants & Redox Signaling 17:2, pages 375-408.
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Irina Ellison & John P. RichieJr.Jr.. (2012) Mechanisms of glutathione disulfide efflux from erythrocytes. Biochemical Pharmacology 83:1, pages 164-169.
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Roberto W. Dal Negro & Richard Hodder. 2012. Long-Term Oxygen Therapy. Long-Term Oxygen Therapy 1 32 .
Stephney Whillier, Barbara Garcia, Bogdan E. Chapman, Philip W. Kuchel & Julia E. Raftos. (2011) Glutamine and α-ketoglutarate as glutamate sources for glutathione synthesis in human erythrocytes. FEBS Journal 278:17, pages 3152-3163.
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Julia E. Raftos, Stephney Whillier & Philip W. Kuchel. (2010) Glutathione Synthesis and Turnover in the Human Erythrocyte. Journal of Biological Chemistry 285:31, pages 23557-23567.
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Fernando J. Martinez. 2009. Pulmonary Arterial Hypertension and Interstitial Lung Diseases. Pulmonary Arterial Hypertension and Interstitial Lung Diseases 177 194 .
Julia E. Raftos, Stephney Whillier, Bogdan E. Chapman & Philip W. Kuchel. (2007) Kinetics of uptake and deacetylation of N-acetylcysteine by human erythrocytes. The International Journal of Biochemistry & Cell Biology 39:9, pages 1698-1706.
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Christelle Koechlin-Ramonatxo. (2006) Oxygène, stress oxydant et supplémentations antioxydantes ou un aspect différent de la nutrition dans les maladies respiratoires. Nutrition Clinique et Métabolisme 20:4, pages 165-177.
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Gabriele LucantoniDonatella PietrafortePaola MatarreseLucrezia GambardellaAlessio MetereGregorino PaoneEnrico Li BianchiElisabetta Straface. (2006) The Red Blood Cell as a Biosensor for Monitoring Oxidative Imbalance in Chronic Obstructive Pulmonary Disease: An Ex Vivo and In Vitro Study . Antioxidants & Redox Signaling 8:7-8, pages 1171-1182.
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Eliza Główka, Alf Lamprecht, Nathalie Ubrich, Philippe Maincent, Janina Lulek, Joël Coulon & Pierre Leroy. (2006) Enhanced cellular uptake of a glutathione selective fluorogenic probe encapsulated in nanoparticles. Nanotechnology 17:10, pages 2546-2552.
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