992
Views
58
CrossRef citations to date
0
Altmetric
Original

The mitochondria targeted antioxidant MitoQ protects against fluoroquinolone-induced oxidative stress and mitochondrial membrane damage in human Achilles tendon cells

, , , &
Pages 323-328 | Received 30 Sep 2008, Published online: 09 Sep 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Katrina L Schmid. (2021) Fluoroquinolones are a potent form of chemotherapy. Clinical and Experimental Optometry 104:3, pages 412-416.
Read now
Martin D. Brand. (2020) Riding the tiger – physiological and pathological effects of superoxide and hydrogen peroxide generated in the mitochondrial matrix. Critical Reviews in Biochemistry and Molecular Biology 55:6, pages 592-661.
Read now
Elisabet Cuyàs, Sara Verdura, Núria Folguera-Blasco, Cristian Bastidas-Velez, Ángel G. Martin, Tomás Alarcón & Javier A. Menendez. (2018) Mitostemness. Cell Cycle 17:8, pages 918-926.
Read now
Sergej M. Ostojic. (2017) Mitochondria-targeted nutraceuticals in sports medicine: a new perspective. Research in Sports Medicine 25:1, pages 91-100.
Read now

Articles from other publishers (54)

Dhanvin Richie GuptaSakshya Singh. (2023) Stem cells: Current applications and future prospects. Indian Journal of Medical Sciences 0, pages 1-5.
Crossref
Bing Wei, Mingliang Ji, Yucheng Lin, Shanzheng Wang, Yuxi Liu, Rui Geng, Xinyue Hu, Li Xu, Zhuang Li, Weituo Zhang & Jun Lu. (2023) Mitochondrial transfer from bone mesenchymal stem cells protects against tendinopathy both in vitro and in vivo. Stem Cell Research & Therapy 14:1.
Crossref
Parisa Sadat Delghandi, Vahid Soleimani, Bibi Sedigheh Fazly Bazzaz & Hossein Hosseinzadeh. (2023) A review on oxidant and antioxidant effects of antibacterial agents: impacts on bacterial cell death and division and therapeutic effects or adverse reactions in humans. Naunyn-Schmiedeberg's Archives of Pharmacology.
Crossref
Haruka Furuta, Mari Yamada, Takuya Nagashima, Shuichi Matsuda, Kazuki Nagayasu, Hisashi Shirakawa & Shuji Kaneko. (2023) Increased expression of glutathione peroxidase 3 prevents tendinopathy by suppressing oxidative stress. Frontiers in Pharmacology 14.
Crossref
Gloria D’Achille & Gianluca Morroni. 2023. Mitochondria and Bacterial Pathogens - Part B. Mitochondria and Bacterial Pathogens - Part B 121 139 .
Stuart James, John Daffy, Jill Cook & Tom Samiric. (2022) Short-Term Exposure to Ciprofloxacin Reduces Proteoglycan Loss in Tendon Explants. Genes 13:12, pages 2210.
Crossref
Carolin Thomas, Lia Wurzer, Ernst Malle, Michael Ristow & Corina T. Madreiter-Sokolowski. (2022) Modulation of Reactive Oxygen Species Homeostasis as a Pleiotropic Effect of Commonly Used Drugs. Frontiers in Aging 3.
Crossref
Pauline Po Yee Lui, Xing Zhang, Shiyi Yao, Haonan Sun & Caihao Huang. (2022) Roles of Oxidative Stress in Acute Tendon Injury and Degenerative Tendinopathy—A Target for Intervention. International Journal of Molecular Sciences 23:7, pages 3571.
Crossref
Bijaideep Dutta, K.C. Barick & P.A. Hassan. (2021) Recent advances in active targeting of nanomaterials for anticancer drug delivery. Advances in Colloid and Interface Science 296, pages 102509.
Crossref
Stuart James, Johannes Schuijers, John Daffy, Jill Cook & Tom Samiric. (2021) Ciprofloxacin reduces tenocyte viability and proteoglycan synthesis in short-term explant cultures of equine tendon. PeerJ 9, pages e12003.
Crossref
Edgar David González-González, Leobardo Manuel Gómez-Oliván, Hariz Islas-Flores & Marcela Galar-Martínez. (2021) Developmental Effects of Amoxicillin at Environmentally Relevant Concentration Using Zebrafish Embryotoxicity Test (ZET). Water, Air, & Soil Pollution 232:5.
Crossref
Ji Min Lee, Jung Wook Hwang, Mi Jin Kim, Sang Youn Jung, Kyung-Soo Kim, Eun Hee Ahn, Kyunghoon Min & Yong-Soo Choi. (2021) Mitochondrial Transplantation Modulates Inflammation and Apoptosis, Alleviating Tendinopathy Both In Vivo and In Vitro. Antioxidants 10:5, pages 696.
Crossref
C. Kabore, Q. Salier, P. Geerts & J.-F. Kaux. (2021) Management of systemic risk factors for chronic tendinopathy. Science & Sports 36:1, pages 5-15.
Crossref
Ekaterina M. Fock & Rimma G. Parnova. (2021) Protective Effect of Mitochondria-Targeted Antioxidants against Inflammatory Response to Lipopolysaccharide Challenge: A Review. Pharmaceutics 13:2, pages 144.
Crossref
Stefan PieperStefan Pieper. 2021. Fluoroquinolone-Associated Disability (FQAD) - Pathogenesis, Diagnostics, Therapy and Diagnostic Criteria. Fluoroquinolone-Associated Disability (FQAD) - Pathogenesis, Diagnostics, Therapy and Diagnostic Criteria 7 16 .
Maria Gracia Luigi-Sierra, Vincenzo Landi, Dailu Guan, Juan Vicente Delgado, Anna Castelló, Betlem Cabrera, Emilio Mármol-Sánchez, Javier Fernández Alvarez, Mayra Gómez-Carpio, Amparo Martínez, Xavier Such, Jordi Jordana & Marcel Amills. (2020) A genome-wide association analysis for body, udder, and leg conformation traits recorded in Murciano-Granadina goats. Journal of Dairy Science 103:12, pages 11605-11617.
Crossref
Leticia Y. Kochi, Patricia L. Freitas, Leila T. Maranho, Philippe Juneau & Marcelo P. Gomes. (2020) Aquatic Macrophytes in Constructed Wetlands: A Fight against Water Pollution. Sustainability 12:21, pages 9202.
Crossref
Marcelo Pedrosa Gomes, Júlio César Moreira Brito, Daiane Cristina Rocha, Mário Antônio Navarro-Silva & Philippe Juneau. (2020) Individual and combined effects of amoxicillin, enrofloxacin, and oxytetracycline on Lemna minor physiology. Ecotoxicology and Environmental Safety 203, pages 111025.
Crossref
Erman Popowski, Benjamin Kohl, Tobias Schneider, Joachim Jankowski & Gundula Schulze-Tanzil. (2020) Uremic Toxins and Ciprofloxacin Affect Human Tenocytes In Vitro. International Journal of Molecular Sciences 21:12, pages 4241.
Crossref
Marcelo Pedrosa Gomes, Daiane Cristina Rocha, Júlio César Moreira de Brito, Davi Santos Tavares, Raizza Zorman Marques, Patrícia Soffiatti & Bruno Francisco Sant’Anna-Santos. (2020) Emerging contaminants in water used for maize irrigation: Economic and food safety losses associated with ciprofloxacin and glyphosate. Ecotoxicology and Environmental Safety 196, pages 110549.
Crossref
Yu-Chuan Liu, Hung-Li Wang, Ying-Zu Huang, Yi-Hsin Weng, Rou-Shayn Chen, Wen-Chung Tsai, Tu-Hsueh Yeh, Chin-Song Lu, Ying-Ling Chen, Yan-Wei Lin, Yu-Jie Chen, Chia-Chen Hsu, Chi-Han Chiu & Ching-Chi Chiu. (2020) Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models. Biochemical Pharmacology 175, pages 113919.
Crossref
Álvaro Mourenza, José A. Gil, Luís M. Mateos & Michal Letek. (2020) Oxidative Stress-Generating Antimicrobials, a Novel Strategy to Overcome Antibacterial Resistance. Antioxidants 9:5, pages 361.
Crossref
André Guillouzo & Christiane Guguen-Guillouzo. (2020) Antibiotics-induced oxidative stress. Current Opinion in Toxicology 20-21, pages 23-28.
Crossref
Ricardo Dionísio, David Daniel, Gilberto Dias de Alkimin & Bruno Nunes. (2020) Multi-parametric analysis of ciprofloxacin toxicity at ecologically relevant levels: Short- and long-term effects on Daphnia magna. Environmental Toxicology and Pharmacology 74, pages 103295.
Crossref
Domenico Rocco Bisaccia, Rocco Aicale, Domiziano Tarantino, Giuseppe M Peretti & Nicola Maffulli. (2019) Biological and chemical changes in fluoroquinolone-associated tendinopathies: a systematic review. British Medical Bulletin 130:1, pages 39-49.
Crossref
Cole A. Fief, Kristine G. Hoang, Stephen D. Phipps, Jessica L. Wallace & Joseph E. Deweese. (2019) Examining the Impact of Antimicrobial Fluoroquinolones on Human DNA Topoisomerase IIα and IIβ. ACS Omega 4:2, pages 4049-4055.
Crossref
Anu Hangas, Koit Aasumets, Nina J Kekäläinen, Mika Paloheinä, Jaakko L Pohjoismäki, Joachim M Gerhold & Steffi Goffart. (2018) Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2. Nucleic Acids Research 46:18, pages 9625-9636.
Crossref
Fang-Yi Su, Selvi Srinivasan, Brian Lee, Jasmin Chen, Anthony J. Convertine, Timothy Eoin West, Daniel M. Ratner, Shawn J. Skerrett & Patrick S. Stayton. (2018) Macrophage-targeted drugamers with enzyme-cleavable linkers deliver high intracellular drug dosing and sustained drug pharmacokinetics against alveolar pulmonary infections. Journal of Controlled Release 287, pages 1-11.
Crossref
Ekaterina Fock, Vera Bachteeva, Elena Lavrova & Rimma Parnova. (2018) Mitochondrial-Targeted Antioxidant MitoQ Prevents E. coli Lipopolysaccharide-Induced Accumulation of Triacylglycerol and Lipid Droplets Biogenesis in Epithelial Cells . Journal of Lipids 2018, pages 1-11.
Crossref
B. Nunes, C. Leal, S. Rodrigues & S. C. Antunes. (2018) Assessment of ecotoxicological effects of ciprofloxacin in Daphnia magna: life-history traits, biochemical and genotoxic effects. Water Science and Technology 2017:3, pages 835-844.
Crossref
Marcelo Pedrosa Gomes, Júlio César Moreira de Brito, Elisa Monteze Bicalho, Janaína Guernica Silva, Maria de Fátima Gomides, Queila Souza Garcia & Cleber Cunha Figueredo. (2018) Ciprofloxacin vs. temperature: Antibiotic toxicity in the free-floating liverwort Ricciocarpus natans from a climate change perspective. Chemosphere 202, pages 410-419.
Crossref
Finosh G. Thankam, Zachary K. Roesch, Matthew F. Dilisio, Mohamed M. Radwan, Anuradha Kovilam, R. Michael Gross & Devendra K. Agrawal. (2018) Association of Inflammatory Responses and ECM Disorganization with HMGB1 Upregulation and NLRP3 Inflammasome Activation in the Injured Rotator Cuff Tendon. Scientific Reports 8:1.
Crossref
Robroy L. Martin, Ruth Chimenti, Tyler Cuddeford, Jeff Houck, J.W. Matheson, Christine M. McDonough, Stephen Paulseth, Dane K. Wukich & Christopher R. Carcia. (2018) Achilles Pain, Stiffness, and Muscle Power Deficits: Midportion Achilles Tendinopathy Revision 2018. Journal of Orthopaedic & Sports Physical Therapy 48:5, pages A1-A38.
Crossref
Jo Marchant. (2018) When antibiotics turn toxic. Nature 555:7697, pages 431-433.
Crossref
Alexandre Leme Godoy-Santos, Homero Bruschini, Jose Cury, Miguel Srougi, Cesar de Cesar-Netto, Lucas F. Fonseca & Nicola Maffulli. (2018) Fluoroquinolones and the Risk of Achilles Tendon Disorders: Update on a Neglected Complication. Urology 113, pages 20-25.
Crossref
Rebecca D. Powell, Donna A. Goodenow, A. Britton Christmas, Iain H. Mckillop & Susan L. Evans. (2020) Effect of Systemic Triphenylphosphonium on Organ Function and Oxidative Stress . The American Surgeon 84:1, pages 36-42.
Crossref
Marcelo Pedrosa Gomes, Júlio César Moreira de Brito, Marília Mércia Lima Carvalho Carneiro, Mariem Rodrigues Ribeiro da Cunha, Queila Souza Garcia & Cleber Cunha Figueredo. (2018) Responses of the nitrogen-fixing aquatic fern Azolla to water contaminated with ciprofloxacin: Impacts on biofertilization. Environmental Pollution 232, pages 293-299.
Crossref
Marcelo Pedrosa Gomes, Cíntia Almeida Gonçalves, Júlio César Moreira de Brito, Amanda Miranda Souza, Fernanda Vieira da Silva Cruz, Elisa Monteze Bicalho, Cleber Cunha Figueredo & Queila Souza Garcia. (2017) Ciprofloxacin induces oxidative stress in duckweed (Lemna minor L.): Implications for energy metabolism and antibiotic-uptake ability. Journal of Hazardous Materials 328, pages 140-149.
Crossref
Krzysztof Michalak, Aleksandra Sobolewska-Włodarczyk, Marcin Włodarczyk, Justyna Sobolewska, Piotr Woźniak & Bogusław Sobolewski. (2017) Treatment of the Fluoroquinolone-Associated Disability: The Pathobiochemical Implications. Oxidative Medicine and Cellular Longevity 2017, pages 1-15.
Crossref
Xiao Yao, Deborah Carlson, Yuxiao Sun, Lisha Ma, Steven E. Wolf, Joseph P. Minei & Qun S. Zang. (2015) Mitochondrial ROS Induces Cardiac Inflammation via a Pathway through mtDNA Damage in a Pneumonia-Related Sepsis Model. PLOS ONE 10:10, pages e0139416.
Crossref
Mohamed Said Arafa Nadia, M Rawi Sayed & Abdullah Mubarak Sara. (2015) Exploration of the neurotoxicity of ciprofloxcin or gatifloxacin single dose in rat cortex and hippocampus. African Journal of Pharmacy and Pharmacology 9:4, pages 65-73.
Crossref
Sara K. BerkelhamerKathryn N. Farrow. (2014) Developmental Regulation of Antioxidant Enzymes and Their Impact on Neonatal Lung Disease. Antioxidants & Redox Signaling 21:13, pages 1837-1848.
Crossref
Hany Ghaly, Anne Jörns & Ingo Rustenbeck. (2014) Effect of fluoroquinolones on mitochondrial function in pancreatic beta cells. European Journal of Pharmaceutical Sciences 52, pages 206-214.
Crossref
Swati Biswas & Vladimir P. Torchilin. (2014) Nanopreparations for organelle-specific delivery in cancer. Advanced Drug Delivery Reviews 66, pages 26-41.
Crossref
Sameer KalghatgiCatherine S. SpinaJames C. CostelloMarc LiesaJ. Ruben Morones-RamirezShimyn SlomovicAnthony MolinaOrian S. ShirihaiJames J. Collins. (2013) Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells. Science Translational Medicine 5:192.
Crossref
Tanecia MitchellBalu ChackoScott W. BallingerShannon M. BaileyJianhua ZhangVictor Darley-Usmar. (2013) Convergent mechanisms for dysregulation of mitochondrial quality control in metabolic disease: implications for mitochondrial therapeutics. Biochemical Society Transactions 41:1, pages 127-133.
Crossref
Qun S. ZangHesham Sadek, David L. MaassBobbie MartinezLisha MaJessica A. Kilgore, Noelle S. Williams, Doug E. Frantz, Jane G. WiggintonFiemu E. NwariakuSteven E. WolfJoseph P. Minei. (2012) Specific inhibition of mitochondrial oxidative stress suppresses inflammation and improves cardiac function in a rat pneumonia-related sepsis model. American Journal of Physiology-Heart and Circulatory Physiology 302:9, pages H1847-H1859.
Crossref
Qi Qian, Samih H. Nasr, Clement O. Akogyeram & Sanjeev Sethi. (2012) Myoglobin-Associated Acute Kidney Injury in the Setting of Ciprofloxacin Administration. American Journal of Kidney Diseases 59:3, pages 462-466.
Crossref
Alexander V. LyubimovMeihua Rose Feng, Nan Zheng, Xinyuan Zhang, Yea Min Huh & Jing-yu Yu. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions.
Ferda Kaleagasioglu & Ercan Olcay. (2012) Fluoroquinolone-Induced Tendinopathy: Etiology and Preventive Measures. The Tohoku Journal of Experimental Medicine 226:4, pages 251-258.
Crossref
Mederic M. Hall, Jonathan T. Finnoff & Jay Smith. (2011) Musculoskeletal Complications of Fluoroquinolones: Guidelines and Precautions for Usage in the Athletic Population. PM&R 3:2, pages 132-142.
Crossref
Heidi E. Doyle. (2010) Tendinopathy resulting from the use of fluoroquinolones:. Journal of the American Academy of Physician Assistants 23:12, pages 18-21.
Crossref
Chin-Ju J. Hsiao, Husam Younis & Urs A. Boelsterli. (2010) Trovafloxacin, a fluoroquinolone antibiotic with hepatotoxic potential, causes mitochondrial peroxynitrite stress in a mouse model of underlying mitochondrial dysfunction. Chemico-Biological Interactions 188:1, pages 204-213.
Crossref
A. Meli?n Ortiz, R. Garc?a P?rez, C. Ortega Orej?n, X. Veiga Monasterioguren, A. S?nchez Campos & N. Senent Sansegundo. (2010) Propuesta de una gu?a de pr?ctica cl?nica para ruptura del tend?n de Aquiles reparado percut?neamente. Fisioterapia 32:5, pages 217-228.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.