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Journal of Receptors and Signal Transduction Volume 28, 2008 - Issue 1-2
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Research Article

GRK2-Dependent Desensitization Downstream of G Proteins

M. JURADO-PUEYO Departamento de Biologia Molecular and Centro de Biologia Molecular “Severo Ochoa,” CSIC-UAM, Cantoblanco, Madrid, Spain
,
P. M. CAMPOS Departamento de Biologia Molecular and Centro de Biologia Molecular “Severo Ochoa,” CSIC-UAM, Cantoblanco, Madrid, Spain
,
F. MAYOR Departamento de Biologia Molecular and Centro de Biologia Molecular “Severo Ochoa,” CSIC-UAM, Cantoblanco, Madrid, Spain
, Jr. &
C. MURGA Departamento de Biologia Molecular and Centro de Biologia Molecular “Severo Ochoa,” CSIC-UAM, Cantoblanco, Madrid, Spain
Pages 59-70 | Published online: 10 Oct 2008

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Meng Wu, Shunyou Long, Anthony G. Frutos, Maryna Eichelberger, Min Li & Ye Fang. (2009) Interrogation of phosphor-specific interaction on a high-throughput label-free optical biosensor system–Epic® system. Journal of Receptors and Signal Transduction 29:3-4, pages 202-210.
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Panagiotis Efentakis, Ioanna Andreadou, Konstantinos E. Iliodromitis, Filippos Triposkiadis, Péter Ferdinandy, Rainer Schulz & Efstathios K. Iliodromitis. (2022) Myocardial Protection and Current Cancer Therapy: Two Opposite Targets with Inevitable Cost. International Journal of Molecular Sciences 23:22, pages 14121.
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Preeti Kumari Chaudhary & Soochong Kim. (2021) The GRKs Reactome: Role in Cell Biology and Pathology. International Journal of Molecular Sciences 22:7, pages 3375.
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Marta Laganà, Géraldine Schlecht-Louf & Françoise Bachelerie. (2021) The G Protein-Coupled Receptor Kinases (GRKs) in Chemokine Receptor-Mediated Immune Cell Migration: From Molecular Cues to Physiopathology. Cells 10:1, pages 75.
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Amy D. Wu, William Dan, Yi Zhang, Shruti Vemaraju, Brian A. Upton, Richard A. Lang, Ethan D. Buhr, Dan E. Berkowitz, George Gallos, Charles W. Emala & Peter D. Yim. (2021) Opsin 3–G αs Promotes Airway Smooth Muscle Relaxation Modulated by G Protein Receptor Kinase 2 . American Journal of Respiratory Cell and Molecular Biology 64:1, pages 59-68.
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Sailesh Palikhe, Wakana Ohashi, Takuya Sakamoto, Kohshi Hattori, Masaaki Kawakami, Tsugunobu Andoh, Hiromi Yamazaki & Yuichi Hattori. (2019) Regulatory Role of GRK2 in the TLR Signaling-Mediated iNOS Induction Pathway in Microglial Cells. Frontiers in Pharmacology 10.
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Zhu Wang, Yantian Chen, Xueyi Li, Pinky Sultana, Ming Yin & Zejian Wang. (2019) Amyloid-β1-42 dynamically regulates the migration of neural stem/progenitor cells via MAPK-ERK pathway. Chemico-Biological Interactions 298, pages 96-103.
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Xiaoyi Qi, Yanjing Guo, Yongfeng Song, Chunxiao Yu, Lifang Zhao, Li Fang, Dehuan Kong, Jiajun Zhao & Ling Gao. (2018) Follicle-stimulating hormone enhances hepatic gluconeogenesis by GRK2-mediated AMPK hyperphosphorylation at Ser485 in mice. Diabetologia 61:5, pages 1180-1192.
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Jason N. Peart, Salvatore Pepe, Melissa E. Reichelt, Nikkie Beckett, Louise See Hoe, Victoria Ozberk, Ingrid R. Niesman, Hemal H. Patel & John P. Headrick. (2014) Dysfunctional survival-signaling and stress-intolerance in aged murine and human myocardium. Experimental Gerontology 50, pages 72-81.
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Isabel Gomez-Monterrey, Alfonso Carotenuto, Ersilia Cipolletta, Marina Sala, Ermelinda Vernieri, Antonio Limatola, Alessia Bertamino, Simona Musella, Paolo Grieco, Bruno Trimarco, Ettore Novellino, Guido Iaccarino & Pietro Campiglia. (2014) SAR study and conformational analysis of a series of novel peptide G protein-coupled receptor kinase 2 inhibitors. Biopolymers 101:1, pages 121-128.
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James D. Robinson & Julie A. Pitcher. (2013) G protein-coupled receptor kinase 2 (GRK2) is a Rho-activated scaffold protein for the ERK MAP kinase cascade. Cellular Signalling 25:12, pages 2831-2839.
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Luisa Iacovelli, Ferdinando Nicoletti & Antonio De Blasi. (2013) Molecular mechanisms that desensitize metabotropic glutamate receptor signaling: An overview. Neuropharmacology 66, pages 24-30.
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Feng-Ling Wang, Li-Qin Tang & Wei Wei. (2012) The connection between GRKs and various signaling pathways involved in diabetic nephropathy. Molecular Biology Reports 39:7, pages 7717-7726.
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Annemieke Kavelaars, Niels Eijkelkamp, Hanneke L.D.M. Willemen, Huijing Wang, Anibal Garza Carbajal & Cobi J. Heijnen. (2011) Microglial GRK2: A novel regulator of transition from acute to chronic pain. Brain, Behavior, and Immunity 25:6, pages 1055-1060.
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Henriette Brinks, Amrit DasWalter J Koch. (2011) A role for GRK2 in myocardial ischemic injury: indicators of a potential future therapy and diagnostic. Future Cardiology 7:4, pages 547-556.
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Lucia Garcia-Guerra, Iria Nieto-Vazquez, Rocio Vila-Bedmar, María Jurado-Pueyo, Guillermo Zalba, Javier Díez, Cristina Murga, Sonia Fernández-Veledo, Federico MayorJr.Jr. & Margarita Lorenzo. (2010) G Protein–Coupled Receptor Kinase 2 Plays a Relevant Role in Insulin Resistance and Obesity. Diabetes 59:10, pages 2407-2417.
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C. Murga, P. Penela, C. Ribas & F MayorJr.Jr.. (2010) G protein-coupled receptor kinases: Specific phosphorylation of 7TM receptors and beyond. Drug Discovery Today: Technologies 7:1, pages e43-e49.
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X. Yu & D. C. Kem. (2009) Proteasome inhibition during myocardial infarction. Cardiovascular Research 85:2, pages 312-320.
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Xichun Yu, Eugene Patterson & David C Kem. (2009) Targeting proteasomes for cardioprotection. Current Opinion in Pharmacology 9:2, pages 167-172.
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