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Amyloid
The Journal of Protein Folding Disorders
Volume 16, 2009 - Issue 2
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Original Article

Excessive fibrinolysis in AL-amyloidosis is induced by urokinae-type plasminogen activator from bone marrow plasma cells

Mitsuhiro Uchiba Department of Blood Transfusion and Cell Therapy, Kumamoto University Hospital, Kumamoto, JapanCorrespondence[email protected]
,
Takahisa Imamura Department of Molecular Pathology
,
Hiroyuki Hata Department of Hematology
,
Hiro Tatetsu Department of Hematology
,
Yuji Yonemura Department of Blood Transfusion and Cell Therapy, Kumamoto University Hospital, Kumamoto, Japan
,
Mitsuharu Ueda Department of Diagnostic Medicine
,
Yoshihiro Wada Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
,
Hiroaki Mitsuya Department of Hematology
&
Yukio Ando Department of Blood Transfusion and Cell Therapy, Kumamoto University Hospital, Kumamoto, Japan; Department of Diagnostic Medicine
 show all
Pages 89-93 | Published online: 13 Aug 2009

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Ryoichi Takahashi, Kenjiro Ono, Tokuhei Ikeda, Akio Akagi, Daisuke Noto, Ichiro Nozaki, Kenji Sakai, Hidesaku Asakura, Kazuo Iwasa & Masahito Yamada. (2012) Coagulation and fibrinolysis abnormalities in familial amyloid polyneuropathy. Amyloid 19:3, pages 129-132.
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Norihiro Suga, Naoto Miura, Wataru Kitagawa, Hiroyuki Morita, Shogo Banno & Hirokazu Imai. (2012) Differential diagnosis of localized and systemic amyloidosis based on coagulation and fibrinolysis parameters. Amyloid 19:2, pages 61-65.
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Articles from other publishers (19)

Søren Thorgaard Bønløkke, Christian Fenger-Eriksen, Hans Beier Ommen & Anne-Mette Hvas. (2023) Impaired fibrinolysis and increased clot strength are potential risk factors for thrombosis in lymphoma. Blood Advances 7:22, pages 7056-7066.
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Irina G. Rekhtina, Victoria A. Khyshova, Nadezhda I. Zozulya, Valentina N. Dvirnyk & Larisa P. Mendeleyeva. (2023) Hemostasis disorders in patients with systemic AL-amyloidosis. Terapevticheskii arkhiv 95:9, pages 746-750.
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Chihiro Shimazaki, Saori Matsui‐Maegawa, Yayoi Kimoto‐Matsumura, Saeko Ota‐Kuwabara, Daisuke Ide, Shin‐ichi Fuchida & Mayumi Hatsuse. (2023) The serum level of plasmin‐alpha2 plasmin inhibitor complex ( PIC ) is useful for differentiating cardiac light chain amyloidosis from transthyretin amyloidosis . British Journal of Haematology.
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Mitsuhiro UCHIBA. (2023) α<sub>2</sub>-antiplasminα<sub>2</sub>-アンチプラスミン. Japanese Journal of Thrombosis and Hemostasis 34:3, pages 299-303.
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José Pardos-Gea, Vicente Cortina, Joana Rita Marques-Soares, Fernanda Martínez & Merche Gironella. (2023) Severe bleeding diathesis as onset of light-chain amyloidosis: combined excessive fibrinolysis and acquired von Willebrand disease in a young patient. Blood Coagulation & Fibrinolysis 34:1, pages 79-81.
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Laura Acquasaliente & Vincenzo De Filippis. (2022) The Role of Proteolysis in Amyloidosis. International Journal of Molecular Sciences 24:1, pages 699.
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Ya-juan Gao, Kai-ni Shen, Long Chang, Jun Feng, Yue-ying Mao, Lu Zhang, Xin-xin Cao, Dao-bin Zhou & Jian Li. (2022) Prevalence, clinical characteristics and treatment outcome of factor X deficiency in a consecutive cohort of primary light-chain amyloidosis. Leukemia Research 120, pages 106917.
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Qijie Ran, Dehong Xu, Qi Wang & Dongsheng Wang. (2022) Hypermethylation of the Promoter Region of miR-23 Enhances the Metastasis and Proliferation of Multiple Myeloma Cells via the Aberrant Expression of uPA. Frontiers in Oncology 12.
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Simone A. Brysland, Muhammad Gohar Maqbool, Dipti Talaulikar & Elizabeth E. Gardiner. 2022.
Filipa Bezerra, Christoph Niemietz, Hartmut H. J. Schmidt, Andree Zibert, Shuling Guo, Brett P. Monia, Paula Gonçalves, Maria João Saraiva & Maria Rosário Almeida. (2021) In Vitro and In Vivo Effects of SerpinA1 on the Modulation of Transthyretin Proteolysis. International Journal of Molecular Sciences 22:17, pages 9488.
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Søren Thorgaard Bønløkke, Hans Beier Ommen & Anne-Mette Hvas. (2021) Altered Fibrinolysis in Hematological Malignances. Seminars in Thrombosis and Hemostasis 47:05, pages 569-580.
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Filipa Bezerra, Maria João Saraiva & Maria Rosário Almeida. (2020) Modulation of the Mechanisms Driving Transthyretin Amyloidosis. Frontiers in Molecular Neuroscience 13.
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Masahisa Arahata, Hiroyuki Takamatsu, Eriko Morishita, Yasuko Kadohira, Shinya Yamada, Akitada Ichinose & Hidesaku Asakura. (2020) Coagulation and fibrinolytic features in AL amyloidosis with abnormal bleeding and usefulness of tranexamic acid. International Journal of Hematology 111:4, pages 550-558.
Crossref
Anita Pudusseri, Vaishali Sanchorawala, J. Mark Sloan, Katherine M. Bever, Gheorghe Doros, Shivangi Kataria & Shayna Sarosiek. (2019) Prevalence and prognostic value of D‐dimer elevation in patients with AL amyloidosis. American Journal of Hematology 94:10, pages 1098-1103.
Crossref
Kanji Miyazaki & Kenshi Suzuki. (2018) Elevation of Plasmin-α2-plasmin Inhibitor Complexes in Patients with AL Amyloidosis. Internal Medicine 57:6, pages 775-776.
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Kazuya Ishiguro, Toshiaki Hayashi, Yoshihiro Yokoyama, Yuka Aoki, Kei Onodera, Hiroshi Ikeda, Tadao Ishida & Hiroshi Nakase. (2018) Elevation of Plasmin-α2-plasmin Inhibitor Complex Predicts the Diagnosis of Systemic AL Amyloidosis in Patients with Monoclonal Protein. Internal Medicine 57:6, pages 783-788.
Crossref
Joseph J. Shatzel, Robyn Scherber & Thomas G. DeLoughery. 2018. Neoplastic Diseases of the Blood. Neoplastic Diseases of the Blood 1263 1289 .
Christina Dicke, Sonja Schneppenheim, Katharina Holstein, Brigitte Spath, Carsten Bokemeyer, Rita Dittmer, Ulrich Budde & Florian Langer. (2016) Distinct mechanisms account for acquired von Willebrand syndrome in plasma cell dyscrasias. Annals of Hematology 95:6, pages 945-957.
Crossref
Mitsuhiro UCHIBA, Hiroyuki HATA, Takahisa IMAMURA & Yukio ANDO. (2010) AL amyloidosis and abnormalities of fibrinolysis. Japanese Journal of Thrombosis and Hemostasis 21:1, pages 9-15.
Crossref

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