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Expert Opinion on Investigational Drugs Volume 25, 2016 - Issue 10
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Review

Investigational glucagon-like peptide-1 agonists for the treatment of obesity

Brian TomlinsonResearch Center for Translational Medicine, Shanghai East Hospital Affiliated to Tongji University School of Medicine, Shanghai, China;Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Shatin, Hong KongCorrespondence[email protected]
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,
Miao HuDepartment of Medicine & Therapeutics, The Chinese University of Hong Kong, Shatin, Hong KongView further author information
,
Yuzhen ZhangResearch Center for Translational Medicine, Shanghai East Hospital Affiliated to Tongji University School of Medicine, Shanghai, ChinaView further author information
,
Paul ChanDivision of Cardiology, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei City, TaiwanCorrespondence[email protected]
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&
Zhong-Min LiuDepartment of Cardiac Surgery, Shanghai East Hospital, Tongji University, Shanghai, ChinaCorrespondence[email protected]
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Pages 1167-1179 | Received 20 Apr 2016, Accepted 04 Aug 2016, Published online: 26 Aug 2016

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Elliot J. Glotfelty, Lars Olson, Tobias E. Karlsson, Yazhou Li & Nigel H. Greig. (2020) Glucagon-like peptide-1 (GLP-1)-based receptor agonists as a treatment for Parkinson’s disease. Expert Opinion on Investigational Drugs 29:6, pages 595-602.
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Raymond S. Norton. (2017) Enhancing the therapeutic potential of peptide toxins. Expert Opinion on Drug Discovery 12:6, pages 611-623.
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André J. Scheen. (2017) Pharmacotherapy of ‘treatment resistant’ type 2 diabetes. Expert Opinion on Pharmacotherapy 18:5, pages 503-515.
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Brian Tomlinson, Miao Hu, Yuzhen Zhang, Paul Chan & Zhong-Min Liu. (2017) Liraglutide for weight management: benefits and risks. Current Medical Research and Opinion 33:3, pages 537-539.
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Asie Sadeghi, Maryam Niknam, Mohammad Amin Momeni-Moghaddam, Maryam Shabani, Hamid Aria, Alireza Bastin, Maryam Teimouri, Reza Meshkani & Hamed Akbari. (2023) Crosstalk between autophagy and insulin resistance: evidence from different tissues. European Journal of Medical Research 28:1.
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Felix F. Lillich, John D. Imig & Ewgenij Proschak. (2021) Multi-Target Approaches in Metabolic Syndrome. Frontiers in Pharmacology 11.
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Brandon T. Milliken, Clinton Elfers, Oleg G. Chepurny, Kylie S. Chichura, Ian R. Sweet, Tito Borner, Matthew R. Hayes, Bart C. De Jonghe, George G. Holz, Christian L. Roth & Robert P. Doyle. (2021) Design and Evaluation of Peptide Dual-Agonists of GLP-1 and NPY2 Receptors for Glucoregulation and Weight Loss with Mitigated Nausea and Emesis. Journal of Medicinal Chemistry 64:2, pages 1127-1138.
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D. Weghuber, A. Forslund, H. Ahlström, A. Alderborn, K. Bergström, S. Brunner, J. Cadamuro, I. Ciba, M. Dahlbom, V. Heu, J. Hofmann, H. Kristinsson, J. Kullberg, A. Ladinger, F. B. Lagler, M. Lidström, H. Manell, M. Meirik, K. Mörwald, K. Roomp, R. Schneider, H. Vilén, K. Widhalm, F. Zsoldos & P. Bergsten. (2020) A 6‐month randomized, double‐blind, placebo‐controlled trial of weekly exenatide in adolescents with obesity. Pediatric Obesity 15:7.
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Lalita Dahiya, Ramandeep Kaur, Rajiv Kumar, Manoj Kumar & Kezia Palta. (2020) GLP-1 Receptor Agonists in Type 2 Diabetes Mellitus. Current Diabetes Reviews 16:4, pages 279-292.
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Yazhou Li, Kelli L. Vaughan, David Tweedie, Jin Jung, Hee Kyung Kim, Ho-Il Choi, Dong Seok Kim, Julie A. Mattison & Nigel H. Greig. (2019) Pharmacokinetics of Exenatide in nonhuman primates following its administration in the form of sustained-release PT320 and Bydureon. Scientific Reports 9:1.
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Stefano Fiorucci, Michele Biagioli & Eleonora Distrutti. (2018) Future trends in the treatment of non-alcoholic steatohepatitis. Pharmacological Research 134, pages 289-298.
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Yingmei Zhang, James R. Sowers & Jun Ren. (2018) Targeting autophagy in obesity: from pathophysiology to management. Nature Reviews Endocrinology 14:6, pages 356-376.
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Trevor W. Stone, Megan McPherson & L. Gail Darlington. (2018) Obesity and Cancer: Existing and New Hypotheses for a Causal Connection. eBioMedicine 30, pages 14-28.
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Yanan Shi, Xinfeng Sun, Liping Zhang, Kaoxiang Sun, Keke Li, Youxin Li & Qiang Zhang. (2018) Fc-modified exenatide-loaded nanoparticles for oral delivery to improve hypoglycemic effects in mice. Scientific Reports 8:1.
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Andrew J. Krentz & Gerardo Rodriguez-Araujo. (2017) Cardiovascular Outcome Trials of Diabetes and Obesity Drugs: Implications for Conditional Approval and Early Phase Clinical Development. Pharmaceutical Medicine 31:6, pages 399-421.
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Renata Kowalczyk, Paul W. R. Harris, Geoffrey M. Williams, Sung-Hyun Yang & Margaret A. Brimble. 2017. Peptides and Peptide-based Biomaterials and their Biomedical Applications. Peptides and Peptide-based Biomaterials and their Biomedical Applications 185 227 .

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