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Research Article

A metabonomic approach to the investigation of drug-induced phospholipidosis: an NMR spectroscopy and pattern recognition study

Pages 410-423 | Published online: 29 Sep 2008

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Hidenori Kamiguchi, Mika Murabayashi, Ikuo Mori, Akira Horinouchi & Kazutaka Higaki. (2017) Biomarker discovery for drug-induced phospholipidosis: phenylacetylglycine to hippuric acid ratio in urine and plasma as potential markers. Biomarkers 22:2, pages 178-188.
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Jong-Chul Park, Young-Shick Hong, Yeon Joo Kim, Ji-Young Yang, Eun-Young Kim, Seung Jun Kwack, Do Hyun Ryu, Geum-Sook Hwang & Byung Mu Lee. (2009) A Metabonomic Study on the Biochemical Effects of Doxorubicin in Rats Using 1H-NMR Spectroscopy. Journal of Toxicology and Environmental Health, Part A 72:6, pages 374-384.
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Mark J Reasor, Kenneth L Hastings & Roger G Ulrich. (2006) Drug-induced phospholipidosis: issues and future directions. Expert Opinion on Drug Safety 5:4, pages 567-583.
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Donald G Robertson, Michael D Reily & J David Baker. (2005) Metabonomics in preclinical drug development. Expert Opinion on Drug Metabolism & Toxicology 1:3, pages 363-376.
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Susan C. Connor, Wen Wu, Brian C. Sweatman, Jodi Manini, John N. Haselden, Daniel J. Crowther & Catherine J. Waterfield. (2004) Effects of feeding and body weight loss on the 1H-NMR-based urine metabolic profiles of male Wistar Han Rats: Implications for biomarker discovery. Biomarkers 9:2, pages 156-179.
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Stephanie Ringeissen, Susan C. Connor, H. Roger Brown, Brian C. Sweatman, Mark P. Hodson, Steve P. Kenny, Richard I. Haworth, Paul Mcgill, Mark A. Price, Mike C. Aylott, Derek J. Nunez, John N. Haselden & Catherine J. Waterfield. (2003) Potential urinary and plasma biomarkers of peroxisome proliferation in the rat: identification of N-methylnicotinamide and N-methyl-4-pyridone-3-carboxamide by 1H nuclear magnetic resonance and high performance liquid chromatography. Biomarkers 8:3-4, pages 240-271.
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Articles from other publishers (68)

Sebastian Schieferdecker, Andreas Eberlein, Esther Vock & Mario Beilmann. (2022) Development of an in silico consensus model for the prediction of the phospholipigenic potential of small molecules. Computational Toxicology 22, pages 100226.
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Xiaojing Fan, Xiye Wang, Mingyang Jiang, Zhili Pei & Shicheng Qiao. (2021) An Improved Stacked Autoencoder for Metabolomic Data Classification. Computational Intelligence and Neuroscience 2021, pages 1-9.
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Enrique Almanza-Aguilera, Mireia Urpi-Sarda, Rafael Llorach, Rosa Vázquez-Fresno, Mar Garcia-Aloy, Francesc Carmona, Alex Sanchez, Francisco Madrid-Gambin, Ramon Estruch, Dolores Corella & Cristina Andres-Lacueva. (2017) Microbial metabolites are associated with a high adherence to a Mediterranean dietary pattern using a 1H-NMR-based untargeted metabolomics approach. The Journal of Nutritional Biochemistry 48, pages 36-43.
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Yu Guo, Zhongfeng Li, Xinfeng Liu, Xiaolan Su, Yijie Li, Jiajie Zhu, Yilin Song, Ping Zhang, Jiande D. Z. Chen, Ruhan Wei, Jianqin Yang & Wei Wei. (2017) 1 H NMR-Based Metabonomic Study of Functional Dyspepsia in Stressed Rats Treated with Chinese Medicine Weikangning . Evidence-Based Complementary and Alternative Medicine 2017, pages 1-18.
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Hidenori Kamiguchi, Masashi Yamaguchi, Mika Murabayashi, Ikuo Mori & Akira Horinouchi. (2016) Method development and validation for simultaneous quantitation of endogenous hippuric acid and phenylacetylglycine in rat urine using liquid chromatography coupled with electrospray ionization tandem mass spectrometry. Journal of Chromatography B 1035, pages 76-83.
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Ryohei HAMAGUCHI & Yukihiro KURODA. (2016) A Novel Biomarker for Cellular Toxicity and Phospholipid Accumulation by Cationic Amphiphilic Drugs. CHROMATOGRAPHY 37:1, pages 35-38.
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