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Biomarkers Volume 11, 2006 - Issue 5
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Research Article

High-performance liquid chromatography (HPLC) determination of inosine, a potential biomarker for initial cardiac ischaemia, using isolated mouse hearts

D. Farthing Department of Pharmaceutics; Department of Clinical Pharmacology and Hypertension
,
L. Xi Department of Cardiology
,
L. Gehr Department of Pediatrics, VCU Medical Center, Virginia Commonwealth University, Richmond, VA, USA
,
D. Sica Department of Clinical Pharmacology and Hypertension
,
T. Larus Department of Clinical Pharmacology and Hypertension
&
H. T. Karnes Department of Pharmaceutics
Pages 449-459 | Received 17 Oct 2005, Published online: 08 Oct 2008

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Yogaraje Gowda C. Varadaiah, Senthilkumar Sivanesan, Shivananda B. Nayak & Kashinath R. Thirumalarao. (2022) Purine metabolites can indicate diabetes progression. Archives of Physiology and Biochemistry 128:1, pages 87-91.
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Don Farthing, Lynne Gehr, H. Thomas Karnes, Domenic Sica, Todd Gehr, Terri Larus, Christine Farthing & Lei Xi. (2007) Effects of salicylic acid on post-ischaemic ventricular function and purine efflux in isolated mouse hearts. Biomarkers 12:6, pages 623-634.
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Articles from other publishers (10)

Sven Heiling, Nadine Knutti, Franziska Scherr, Jörg Geiger, Juliane Weikert, Michael Rose, Roland Jahns, Uta Ceglarek, André Scherag & Michael Kiehntopf. (2021) Metabolite Ratios as Quality Indicators for Pre-Analytical Variation in Serum and EDTA Plasma. Metabolites 11:9, pages 638.
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Francisney Pinto Nascimento, Sérgio José Macedo-Júnior, Fernanda Rocha Lapa-Costa, Fernando Cezar-dos-Santos & Adair R. S. Santos. (2021) Inosine as a Tool to Understand and Treat Central Nervous System Disorders: A Neglected Actor?. Frontiers in Neuroscience 15.
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Kaden K. Fujita, Zhe Xia, Gregg Tomy, Tony Montina & Steve Wiseman. (2021) 1H NMR based metabolomic profiling of early life stage zebrafish (Danio rerio) exposed to a water-soluble fraction of weathered sediment-bound diluted bitumen. Aquatic Toxicology 232, pages 105766.
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Owain Fisher, Ruth A Benson & Christopher HE Imray. (2019) The clinical application of purine nucleosides as biomarkers of tissue Ischemia and hypoxia in humans in vivo . Biomarkers in Medicine 13:11, pages 953-964.
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Nornazliya Mohamad, Rose Iszati Ismet, MohdSalleh Rofiee, Zakaria Bannur, Thomas Hennessy, Manikandan Selvaraj, Aminuddin Ahmad, FadzilahMohd Nor, ThuhairahHasrah Abdul Rahman, Kamarudzaman Md.Isa, AdzroolIdzwan Ismail, Lay Kek Teh & Mohd Zaki Salleh. (2015) Metabolomics and partial least square discriminant analysis to predict history of myocardial infarction of self-claimed healthy subjects: validity and feasibility for clinical practice. Journal of Clinical Bioinformatics 5:1.
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Marc R. Elie, Jaewoo Choi, Yasmeen M. Nkrumah-Elie, Gregory D. Gonnerman, Jan F. Stevens & Robert L. Tanguay. (2015) Metabolomic analysis to define and compare the effects of PAHs and oxygenated PAHs in developing zebrafish. Environmental Research 140, pages 502-510.
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Don E Farthing, Christine A Farthing & Lei Xi. (2015) Inosine and hypoxanthine as novel biomarkers for cardiac ischemia: From bench to point-of-care. Experimental Biology and Medicine 240:6, pages 821-831.
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Elodie Robin, Jessica Sabourin, Fabrice Marcillac & Eric Raddatz. (2013) Involvement of CD73, equilibrative nucleoside transporters and inosine in rhythm and conduction disturbances mediated by adenosine A1 and A2A receptors in the developing heart. Journal of Molecular and Cellular Cardiology 63, pages 14-25.
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Anjali K. Nath, Lee D. Roberts, Yan Liu, Sari B. Mahon, Sonia Kim, Justine H. Ryu, Andreas Werdich, James L. Januzzi, Gerry R. Boss, Gary A. Rockwood, Calum A. MacRae, Matthew Brenner, Robert E. Gerszten & Randall T. Peterson. (2013) Chemical and metabolomic screens identify novel biomarkers and antidotes for cyanide exposure. The FASEB Journal 27:5, pages 1928-1938.
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Don Farthing, Domenic Sica, Todd Gehr, Bill Wilson, Itaf Fakhry, Terri Larus, Christine Farthing & H. Thomas Karnes. (2007) An HPLC method for determination of inosine and hypoxanthine in human plasma from healthy volunteers and patients presenting with potential acute cardiac ischemia. Journal of Chromatography B 854:1-2, pages 158-164.
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