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Research Article

Analysis of dialkyl phosphate metabolites in hair using gas chromatography-mass spectrometry: A biomarker of chronic exposure to organophosphate pesticides

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Pages 137-147 | Received 23 Jul 2008, Accepted 02 Feb 2009, Published online: 01 May 2009

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A.M. Tsatsakis, M.N. Tzatzarakis, D. Koutroulakis, M. Toutoudaki & S. Sifakis. (2009) Dialkyl phosphates in meconium as a biomarker of prenatal exposure to organophosphate pesticides: A study on pregnant women of rural areas in Crete, Greece. Xenobiotica 39:5, pages 364-373.
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Articles from other publishers (37)

Shiyi Zhang, Xiao Yan, Bin Tang, Weikeng Luo, Shejun Chen, Xiaojun Luo, Jing Zheng, Bixian Mai & Yunjiang Yu. (2023) Human hair as a noninvasive matrix to assess exposure to micro-organic contaminants: State of the art review. Science of The Total Environment 892, pages 164341.
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I. Katsikantami, A.M. Tsatsakis & I.N. Tsakiris. (2023) CEC06-05: Examples of pesticide occupational exposure monitoring in the field. Toxicology Letters 384, pages S15-S16.
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Lu Han & Qi Wang. (2023) Association between organophosphorus insecticides exposure and the prevalence of sleep problems in the US adults: An analysis based on the NHANES 2007–2018. Ecotoxicology and Environmental Safety 255, pages 114803.
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Samaneh Sepahi, Sina Gerayli, Mohammad Delirrad, Mohammad Ehsan Taghavizadeh Yazdi, Hadi Zare‐Zardini, Behzad Bushehri & Adel Ghorani‐Azam. (2022) Biochemical responses as early and reliable biomarkers of organophosphate and carbamate pesticides intoxication: A systematic literature review. Journal of Biochemical and Molecular Toxicology 37:3.
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Aristidis M. Tsatsakis, Athanasios Alegakis, Ioanna Katsikantami & VN Rakitskii. 2021. Exposure and Risk Assessment of Pesticide Use in Agriculture. Exposure and Risk Assessment of Pesticide Use in Agriculture 103 117 .
Antonio F. Hernández, David Lozano-Paniagua, Beatriz González-Alzaga, Matthaios P. Kavvalakis, Manolis N. Tzatzarakis, Inmaculada López-Flores, Clemente Aguilar-Garduño, Rafael A. Caparros-Gonzalez, Aristidis M. Tsatsakis & Marina Lacasaña. (2019) Biomonitoring of common organophosphate metabolites in hair and urine of children from an agricultural community. Environment International 131, pages 104997.
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Antonio F. Hernández, Fernando Gil & Aristidis M. Tsatsakis. 2019. Biomarkers in Toxicology. Biomarkers in Toxicology 569 585 .
Nathalie Grova, Emilie M. Hardy, François Faÿs, Radu C. Duca & Brice M. R. Appenzeller. (2018) Hair analysis for the biomonitoring of polycyclic aromatic hydrocarbon exposure: comparison with urinary metabolites and DNA adducts in a rat model. Archives of Toxicology 92:10, pages 3061-3075.
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Enea Pagliano, Beatrice Campanella, Alessandro D'Ulivo & Zoltán Mester. (2018) Derivatization chemistries for the determination of inorganic anions and structurally related compounds by gas chromatography - A review. Analytica Chimica Acta 1025, pages 12-40.
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Xiana González-Gómez, Noelia Cambeiro-Pérez, Elena Martínez-Carballo & Jesús Simal-Gándara. (2018) Screening of organic pollutants in pet hair samples and the significance of environmental factors. Science of The Total Environment 625, pages 311-319.
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Ruth BevanTerry BrownFranziska MatthiesCraig SamsKate JonesJames HanlonMax La Vedrine. (2017) Human biomonitoring data collection from occupational exposure to pesticides. EFSA Supporting Publications 14:3.
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Dimitrios Tsikas. (2017) Pentafluorobenzyl bromide—A versatile derivatization agent in chromatography and mass spectrometry: I. Analysis of inorganic anions and organophosphates. Journal of Chromatography B 1043, pages 187-201.
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Amanda S. Appel & Brian A. Logue. (2016) Analysis of nerve agent metabolites from nail clippings by liquid chromatography tandem mass spectrometry. Journal of Chromatography B 1031, pages 116-122.
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Amanda S. Appel, John H. McDonough, Joseph D. McMonagle & Brian A. Logue. (2016) Analysis of Nerve Agent Metabolites from Hair for Long-Term Verification of Nerve Agent Exposure. Analytical Chemistry 88:12, pages 6523-6530.
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D.W. Knipe, C. Jayasumana, S. Siribaddana, C. Priyadarshana, M. Pearson, D. Gunnell, C. Metcalfe, M.N. Tzatzarakis & A.M. Tsatsakis. (2016) Feasibility of hair sampling to assess levels of organophosphate metabolites in rural areas of Sri Lanka. Environmental Research 147, pages 207-211.
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Emilie M. Hardy, Radu C. Duca, Guillaume Salquebre & Brice M.R. Appenzeller. (2015) Multi-residue analysis of organic pollutants in hair and urine for matrices comparison. Forensic Science International 249, pages 6-19.
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Brice M.R. Appenzeller. 2015. Hair Analysis in Clinical and Forensic Toxicology. Hair Analysis in Clinical and Forensic Toxicology 179 196 .
Michalis Michalakis, Manolis N. Tzatzarakis, Leda Kovatsi, Athanasios K. Alegakis, Andreas K. Tsakalof, Ioannis Heretis & Aristidis Tsatsakis. (2014) Hypospadias in offspring is associated with chronic exposure of parents to organophosphate and organochlorine pesticides. Toxicology Letters 230:2, pages 139-145.
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Aikaterini Kokkinaki, Manolis Kokkinakis, Matthaios P. Kavvalakis, Manolis N. Tzatzarakis, Athanasios K. Alegakis, George Maravgakis, Fotoula Babatsikou, Georgios A. Fragkiadakis & Aristidis M. Tsatsakis. (2014) Biomonitoring of dialkylphosphate metabolites (DAPs) in urine and hair samples of sprayers and rural residents of Crete, Greece. Environmental Research 134, pages 181-187.
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D. Koutroulakis, S. Sifakis, M.N. Tzatzarakis, A.K. Alegakis, E. Theodoropoulou, M.P. Kavvalakis, D. Kappou & A.M. Tsatsakis. (2014) Dialkyl phosphates in amniotic fluid as a biomarker of fetal exposure to organophosphates in Crete, Greece; association with fetal growth. Reproductive Toxicology 46, pages 98-105.
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Radu-Corneliu Duca, Emilie Hardy, Guillaume Salquèbre & Brice M. R. Appenzeller. (2014) Hair decontamination procedure prior to multi-class pesticide analysis. Drug Testing and Analysis 6:S1, pages 55-66.
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Radu-Corneliu Duca, Guillaume Salquebre, Emilie Hardy & Brice M.R. Appenzeller. (2014) Comparison of solid phase- and liquid/liquid-extraction for the purification of hair extract prior to multi-class pesticides analysis. Journal of Chromatography B 955-956, pages 98-107.
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Ying Zhang, Song Han, Duohong Liang, Xinzhu Shi, Fengzhi Wang, Wei Liu, Li Zhang, Lixin Chen, Yingzi Gu & Ying Tian. (2014) Prenatal Exposure to Organophosphate Pesticides and Neurobehavioral Development of Neonates: A Birth Cohort Study in Shenyang, China. PLoS ONE 9:2, pages e88491.
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Michalis Koureas, Andreas Tsakalof, Manolis Tzatzarakis, Elena Vakonaki, Aristidis Tsatsakis & Christos Hadjichristodoulou. (2014) Biomonitoring of organophosphate exposure of pesticide sprayers and comparison of exposure levels with other population groups in Thessaly (Greece). Occupational and Environmental Medicine 71:2, pages 126-133.
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Antonio F. Hernández, Fernando Gil & Aristides M. Tsatsakis. 2014. Biomarkers in Toxicology. Biomarkers in Toxicology 655 669 .
Nathalie Grova, Guillaume Salquèbre & Brice M. R. Appenzeller. (2013) Gas chromatography–tandem mass spectrometry analysis of 52 monohydroxylated metabolites of polycyclic aromatic hydrocarbons in hairs of rats after controlled exposure. Analytical and Bioanalytical Chemistry 405:27, pages 8897-8911.
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Bartosz Wielgomas, Wojciech Czarnowski & Eugene H.J.M. Jansen. (2012) Persistent organochlorine contaminants in hair samples of Northern Poland population, 1968–2009. Chemosphere 89:8, pages 975-981.
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Matthaios P. Kavvalakis & Aristidis M. Tsatsakis. (2012) The atlas of dialkylphosphates; assessment of cumulative human organophosphorus pesticides’ exposure. Forensic Science International 218:1-3, pages 111-122.
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Brice M.R. Appenzeller & Aristidis M. Tsatsakis. (2012) Hair analysis for biomonitoring of environmental and occupational exposure to organic pollutants: State of the art, critical review and future needs. Toxicology Letters 210:2, pages 119-140.
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Michalis Koureas, Andreas Tsakalof, Aristidis Tsatsakis & Christos Hadjichristodoulou. (2012) Systematic review of biomonitoring studies to determine the association between exposure to organophosphorus and pyrethroid insecticides and human health outcomes. Toxicology Letters 210:2, pages 155-168.
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AM Tsatsakis, M Tutudaki, MN Tzatzarakis, A Dawson, F Mohamed, M Christaki & AK Alegakis. (2011) Is hair analysis for dialkyl phosphate metabolites a suitable biomarker for assessing past acute exposure to organophosphate pesticides?. Human & Experimental Toxicology 31:3, pages 266-273.
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A.M. Tsatsakis, M.G. Barbounis, M. Kavalakis, M. Kokkinakis, I. Terzi & M.N. Tzatzarakis. (2010) Determination of dialkyl phosphates in human hair for the biomonitoring of exposure to organophosphate pesticides. Journal of Chromatography B 878:17-18, pages 1246-1252.
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Jun Ueyama, Michihiro Kamijima, Takaaki Kondo, Kenji Takagi, Eiji Shibata, Takaaki Hasegawa, Shinya Wakusawa, Tomoko Taki, Masahiro Gotoh & Isao Saito. (2010) Revised method for routine determination of urinary dialkyl phosphates using gas chromatography–mass spectrometry. Journal of Chromatography B 878:17-18, pages 1257-1263.
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. (2010) Current Awareness in Drug Testing and Analysis. Drug Testing and Analysis 1:11-12, pages 596-611.
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Maria G. Margariti & Aristidis M. Tsatsakis. (2009) Assessment of long-term subacute exposure to dimethoate by hair analysis of dialkyl phosphates DMP and DMTP in exposed rabbits: The effects of dose, dose duration and hair colour. Environmental Research 109:7, pages 821-829.
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. (2009) Current literature in mass spectrometry. Journal of Mass Spectrometry 44:10, pages 1542-1553.
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A. Tsatsakis, M. Toutoudaki & M. Tzatzarakis. 2009. Counteraction to Chemical and Biological Terrorism in East European Countries. Counteraction to Chemical and Biological Terrorism in East European Countries 203 211 .

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