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Original

Adding to the controversy: Pitfalls in the diagnosis of testosterone deficiency syndromes with questionnaires and biochemistry

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Pages 57-65 | Received 14 Sep 2006, Accepted 15 Mar 2007, Published online: 06 Jul 2009

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Malcolm Carruthers, Paul Cathcart & Mark R. Feneley. (2015) Evolution of testosterone treatment over 25 years: symptom responses, endocrine profiles and cardiovascular changes. The Aging Male 18:4, pages 217-227.
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Aaron M. Bernie, Jason M. Scovell & Ranjith Ramasamy. (2014) Comparison of questionnaires used for screening and symptom identification in hypogonadal men. The Aging Male 17:4, pages 195-198.
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Tom R. Trinick, Mark R. Feneley, Hugh Welford & Malcolm Carruthers. (2011) International web survey shows high prevalence of symptomatic testosterone deficiency in men. The Aging Male 14:1, pages 10-15.
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Nazem Bassil, Saad Alkaade & John E Morley. (2009) The benefits and risks of testosterone replacement therapy: a review. Therapeutics and Clinical Risk Management 5, pages 427-448.
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Christina Wang, Eberhard Nieschlag, Ronald S. Swerdloff, Hermann Behre, Wayne J. Hellstrom, Louis J. Gooren, Jean M. Kaufman, Jean-Jacques Legros, Bruno Lunenfeld, Alvaro Morales, John E. Morley, Claude Schulman, Ian M. Thompson, Wolfgang Weidner & Frederick C. W. Wu. (2009) ISA, ISSAM, EAU, EAA and ASA recommendations: investigation, treatment and monitoring of late-onset hypogonadism in males. The Aging Male 12:1, pages 5-12.
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Paul G. Cohen. (2008) Pitfalls in the diagnosis of testosterone deficiency. The Aging Male 11:2, pages 49-50.
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Malcolm Carruthers. (2008) The diagnosis of late life hypogonadism. The Aging Male 11:1, pages 45-46.
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Alvaro Morales. (2008) The onset of late life hypogonadism. The Aging Male 11:1, pages 43-43.
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Ravi Kant, Shruti Barnwal, Poonam Yadav, Akshay Malik & Puneet Dhamija. (2023) Clinical outcome of testosterone supplementation assessed by andropausal male symptom scores in type 2 diabetes testosterone-deficient patients receiving testosterone compared to those not receiving testosterone: A nested case-control study. Diabetes & Metabolic Syndrome: Clinical Research & Reviews 17:5, pages 102764.
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G. Brown & B. K. Somani. (2022) Atlas of 35 patient reported outcome measures (PROMs) in andrology: a comprehensive overview of literature. World Journal of Urology 41:2, pages 371-404.
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Patrice Lopès & François-Xavier Poudat. 2021. Manuel de Sexologie. Manuel de Sexologie 103 139 .
Tharu Tharakan, Saiful Miah, Channa Jayasena & Suks Minhas. (2019) Investigating the basis of sexual dysfunction during late-onset hypogonadism. F1000Research 8, pages 331.
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Zhangshun Liu, Jie Liu, Xiaohong Shi, Lihong Wang, Yan Yang, Minfang Tao & Qiang Fu. (2017) Comparing calculated free testosterone with total testosterone for screening and diagnosing late-onset hypogonadism in aged males: A cross-sectional study. Journal of Clinical Laboratory Analysis 31:5, pages e22073.
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Enrique Gavilán, Laura Jiménez de Gracia & Juan Gérvas. (2014) Estrategias de promoción del síndrome por déficit de testosterona: un caso paradigmático de invención de enfermedad (disease mongering). Gaceta Sanitaria 28:2, pages 173-176.
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Juan Gérvas, Enrique Gavilán & Javier Gorricho. (2013) La secreción de testosterona decae naturalmente con la edad. El síndrome por déficit de testosterona es una enfermedad inventada. FMC - Formación Médica Continuada en Atención Primaria 20:10, pages 580-584.
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A. M. Horstman, E. L. Dillon, R. J. Urban & M. Sheffield-Moore. (2012) The Role of Androgens and Estrogens on Healthy Aging and Longevity. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 67:11, pages 1140-1152.
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K.-S. Chueh, S.-P. Huang, Y.-C. Lee, C.-J. Wang, H.-C. Yeh, W.-M. Li, W.-J. Wu, Y.-F. Tsai, C.-C. Tsai, H.-C. Juan, C.-H. Huang & C.-C. Liu. (2012) The Comparison of the Aging Male Symptoms (AMS) Scale and Androgen Deficiency in the Aging Male (ADAM) Questionnaire to Detect Androgen Deficiency in Middle-Aged Men. Journal of Andrology 33:5, pages 817-823.
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Mousumi Biswas, David Hampton, Robert G. Newcombe & D. Aled Rees. (2012) Total and free testosterone concentrations are strongly influenced by age and central obesity in men with type 1 and type 2 diabetes but correlate weakly with symptoms of androgen deficiency and diabetes‐related quality of life. Clinical Endocrinology 76:5, pages 665-673.
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Alvaro Morales. 2012. Campbell-Walsh Urology. Campbell-Walsh Urology 810 822.e3 .
Arthur L. Burnett. 2012. Campbell-Walsh Urology. Campbell-Walsh Urology 721 748.e7 .
Alvaro Morales. (2011) Androgens are Fundamental in the Maintenance of Male Sexual Health. Current Urology Reports 12:6, pages 453-460.
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M. H. Emmelot-Vonk, H. J. J. Verhaar, H. R. Nakhai-Pour, D. E. Grobbee & Y. T. van der Schouw. (2011) Low testosterone concentrations and the symptoms of testosterone deficiency according to the Androgen Deficiency in Ageing Males (ADAM) and Ageing Males’ Symptoms rating scale (AMS) questionnaires. Clinical Endocrinology 74:4, pages 488-494.
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Kweon Sik MinDong Il Kang. (2011) Testosterone replacement therapy and monitoring for the male patients with testosterone deficiency syndrome. Journal of the Korean Medical Association 54:2, pages 197.
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Jin Wook KimDu Geon Moon. (2011) Diagnosis and Treatment of Sexual Dysfunctions in Late-Onset Hypogonadism. Korean Journal of Urology 52:11, pages 725.
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- CHRISTINA WANG, - EBERHARD NIESCHLAG, S. SWERDLOFF RONALD, - HERMANN BEHRE, J. HELLSTROM WAYNE, J. GOOREN LOUIS, M. KAUFMAN JEAN, - JEAN-JACQUES LEGROS, - BRUNO LUNENFELD, - ALVARO MORALES, E. MORLEY JOHN, - CLAUDE SCHULMAN, M. THOMPSON IAN, - WOLFGANG WEIDNER & C.W. WU FREDERICK. (2010) Rekomendatsii ISA, ISSAM, EAU, EAA i ASA: diagnostika, lechenie i monitorirovanie vozrastnogogipogonadizma u muzhchin. Obesity and metabolism 7:2, pages 56-63.
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J. Alexander Fraser, Beau B. Bruce, Janet Rucker, Lisa-Ann Fraser, Edward J. Atkins, Nancy J. Newman & Valérie Biousse. (2010) Risk factors for idiopathic intracranial hypertension in men: A case–control study. Journal of the Neurological Sciences 290:1-2, pages 86-89.
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Juan E. Blümel, Peter Chedraui, Sebastian A. Gili, Alejandra Navarro, Karen Valenzuela & Soledad Vallejo. (2009) Is the Androgen Deficiency of Aging Men (ADAM) questionnaire useful for the screening of partial androgenic deficiency of aging men?. Maturitas 63:4, pages 365-368.
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C. Wang, E. Nieschlag, R. Swerdloff, H. M. Behre, W. J. Hellstrom, L. J. Gooren, J. M. Kaufman, J.-J. Legros, B. Lunenfeld, A. Morales, J. E. Morley, C. Schulman, I. M. Thompson, W. Weidner & F. C. W. Wu. (2009) Investigation, treatment and monitoring of late-onset hypogonadism in males. International Journal of Andrology 32:1, pages 1-10.
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C Wang, E Nieschlag, R Swerdloff, H M Behre, W J Hellstrom, L J Gooren, J M Kaufman, J-J Legros, B Lunenfeld, A Morales, J E Morley, C Schulman, I M Thompson, W Weidner & F C W Wu. (2008) ISA, ISSAM, EAU, EAA and ASA recommendations: Investigation, treatment and monitoring of late-onset hypogonadism in males. International Journal of Impotence Research 21:1, pages 1-8.
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Christina Wang, Eberhard Nieschlag, Ronald Swerdloff, Hermann M. Behre, Wayne J. Hellstrom, Louis J. Gooren, Jean M. Kaufman, Jean-Jacques Legros, Bruno Lunenfeld, Alvaro Morales, John E. Morley, Claude Schulman, Ian M. Thompson, Wolfgang Weidner & Frederick C.W. Wu. (2009) Investigation, Treatment, and Monitoring of Late-Onset Hypogonadism in Males: ISA, ISSAM, EAU, EAA, and ASA Recommendations. European Urology 55:1, pages 121-130.
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. (2008) Current World Literature. Current Opinion in Endocrinology, Diabetes & Obesity 15:4, pages 383-400.
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. (2008) Current World Literature. Current Opinion in Endocrinology, Diabetes & Obesity 15:3, pages 284-314.
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Revital Amiaz & Stuart N Seidman. (2008) Testosterone and depression in men. Current Opinion in Endocrinology, Diabetes & Obesity 15:3, pages 278-283.
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Malcolm Carruthers. (2008) The Paradox Dividing Testosterone Deficiency Symptoms and Androgen Assays: A Closer Look at the Cellular and Molecular Mechanisms of Androgen Action. The Journal of Sexual Medicine 5:4, pages 998-1012.
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Christina Wang. (2007) Challenges in the Diagnosis of the Right Patient for Testosterone Replacement Therapy. European Urology Supplements 6:17, pages 862-867.
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