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Research Article

Determination of Major Constituents in St. John's Wort Under Different Extraction Conditions

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Pages 83-89 | Published online: 03 Oct 2008

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Carmen Elena Ţebrencu, Tanţa-Verona Iordache, Elena Ionescu, Ruxandra Mihaela Creţu, Ana-Mihaela Florea, Sandu Teodor, Steluta Apostol, Anamaria Zaharia, Anita-Laura Radu & Andrei Sârbu. (2020) Straightforward Preparation of Naphtodianthrone-Rich Ethanolic Extracts from Wild St. John’s Wort. Journal of Dietary Supplements 17:1, pages 88-96.
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Sadiye Gunpinar, Olgu Alperat Kilic, Ismet Duran, Mehmet Tosun, Tulin Firat & Gizem Soyler. (2020) Evaluation of the Effect of Topical Hypericum perforatum Oil on Excisional Palatal Wound Healing in Rabbits. Journal of Investigative Surgery 33:1, pages 49-58.
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Magdalena Biesaga & Krystyna Pyrzynska. (2009) Analytical Procedures for Determination of Quercetin and its Glycosides in Plant Material. Critical Reviews in Analytical Chemistry 39:2, pages 95-107.
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Articles from other publishers (23)

Z. A. Temerdashev, E. A. Vinitskaya & V. V. Korobkova. (2022) Determination of Phenolic Compounds in Hypericum perforatum L. Aqueous Extracts by Gas Chromatography–Mass Spectrometry Using Solid-Phase Analytical Derivatization. Journal of Analytical Chemistry 77:11, pages 1463-1473.
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Milos Beran, Ales Horna, Viktor Vorisek, Eliska Berkova, Radka Korinkova, Vojtech Trousil & Marketa Hrubanova. (2022) Antimicrobial polyhydroxybutyrate submicron fiber mat loaded with extract of Hypericum perforatum . Journal of Plant Biotechnology 49:3, pages 257-270.
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Abdalrahim Alahmad, Ibrahim Alghoraibi, Raghad Zein, Sergej Kraft, Gerald Dräger, Johanna-Gabriela Walter & Thomas Scheper. (2022) Identification of Major Constituents of Hypericum perforatum L. Extracts in Syria by Development of a Rapid, Simple, and Reproducible HPLC-ESI-Q-TOF MS Analysis and Their Antioxidant Activities . ACS Omega 7:16, pages 13475-13493.
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Jelena Zvezdanović. (2021) UHPLC–DAD–ESI–MS/MS characterization of St. John’s wort infusions from Serbia origin. Chemical Papers 76:3, pages 1329-1347.
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Borivoj Adnadjevic, Biljana Koturevic & Jelena Jovanovic. (2020) Isothermal kinetics of ethanolic extraction of total hypericin from pre‐extracted Hypericum perforatum flowers . Phytochemical Analysis 32:5, pages 757-766.
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Antigoni Oreopoulou, Evanthia Choulitoudi, Dimitrios Tsimogiannis & Vassiliki Oreopoulou. (2021) Six Common Herbs with Distinctive Bioactive, Antioxidant Components. A Review of Their Separation Techniques. Molecules 26:10, pages 2920.
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Biljana Koturevic, Borivoj Adnadjevic & Jelena Jovanovic. (2021) Comparative kinetic analysis of total hypericin extraction from Hypericum perforatum flowers carried out under simultaneous external physical field and cooling reaction system operational conditions. Chemical Engineering Research and Design 165, pages 106-117.
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Milena Tresch, Meike Mevissen, Hannah Ayrle, Matthias Melzig, Petra Roosje & Michael Walkenhorst. (2019) Medicinal plants as therapeutic options for topical treatment in canine dermatology? A systematic review. BMC Veterinary Research 15:1.
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V.V. Milevskaya, Surendra Prasad & Z.A. Temerdashev. (2019) Extraction and chromatographic determination of phenolic compounds from medicinal herbs in the Lamiaceae and Hypericaceae families: A review. Microchemical Journal 145, pages 1036-1049.
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Eirini Sarrou, Lefki-Pavlina Giassafaki, Domenico Masuero, Daniele Perenzoni, Ioannis S. Vizirianakis, Maria Irakli, Paschalina Chatzopoulou & Stefan Martens. (2018) Metabolomics assisted fingerprint of Hypericum perforatum chemotypes and assessment of their cytotoxic activity. Food and Chemical Toxicology 114, pages 325-333.
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Konstantina Zeliou, Nikos I. Kontaxis, Evangelia Margianni, Christos Petrou & Fotini N. Lamari. (2017) Optimized and Validated HPLC Analysis of St. John's Wort Extract and Final Products by Simultaneous Determination of Major Ingredients. Journal of Chromatographic Science 55:8, pages 805-812.
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Jessica L. Tingle, Susan C. Cook-Patton & Anurag A. Agrawal. (2016) Spillover of a biological control agent ( Chrysolina quadrigemina ) onto native St. Johnswort ( Hypericum punctatum ) . PeerJ 4, pages e1886.
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V. V. Milevskaya, M. A. Statkus, Z. A. Temerdashev, N. V. Kiseleva & N. A. Vernikovskaya. (2015) Methods for the extraction of biologically active substances from medicinal plants based on an example of St. John’s wort components. Journal of Analytical Chemistry 70:12, pages 1432-1440.
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Trent Mortensen, Shujie Shen, FenAnn Shen, Marie K. Walsh, Ronald C. Sims & Charles D. Miller. (2012) Investigating the Effectiveness of St John's Wort Herb as an Antimicrobial Agent against Mycobacteria. Phytotherapy Research 26:9, pages 1327-1333.
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Edita Bagdonaite, Valdimaras Janulis, Liudas Ivanauskas & Juozas Labokas. (2012) Between Species Diversity of Hypericum Perforatum and H. maculatum by the Content of Bioactive Compounds . Natural Product Communications 7:2, pages 1934578X1200700.
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Edita Bagdonaitė, Pavol Mártonfi, Miroslav Repčák & Juozas Labokas. (2012) Variation in concentrations of major bioactive compounds in Hypericum perforatum L. from Lithuania. Industrial Crops and Products 35:1, pages 302-308.
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Edita Bagdonaitė, Pavol Mártonfi, Miroslav Repčák & Juozas Labokas. (2010) Variation in the contents of pseudohypericin and hypericin in Hypericum perforatum from Lithuania. Biochemical Systematics and Ecology 38:4, pages 634-640.
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Alessandra Bertoli, Annalisa Giovannini, Barbara Ruffoni, Angela Di Guardo, Guido Spinelli, Michele Mazzetti & Luisa Pistelli. (2008) Bioactive Constituent Production in St. John’s Wort in Vitro Hairy Roots. Regenerated Plant Lines. Journal of Agricultural and Food Chemistry 56:13, pages 5078-5082.
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M. Biesaga, A. Stafiej & K. Pyrzynska. (2007) Extraction and Hydrolysis Parameters for Determination of Quercetin in Hypericum perforatum. Chromatographia 65:11-12, pages 701-706.
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Guilhem Pages, Corinne Delaurent, Roger Phan-Tan-Luu & Michelle Sergent. (2007) Different chemometric approaches to optimize the assay of St. John's Wort active ingredients. Chemometrics and Intelligent Laboratory Systems 86:2, pages 159-167.
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Pavol Mártonfi, Miroslav Repčák & Lenka Mártonfiová. (2006) Secondary metabolites during ontogenetic phase of reproductive structures in Hypericum maculatum. Biologia 61:4, pages 473-478.
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Guilhem Pages, Michael Mazarin, Michelle Sergent, Roger Phan-Tan-Luu & Corinne Delaurent. (2006) Optimization of the assay of naphthodianthrones in dry St John’s wort extract by reversed-phase liquid chromatography. Analytical and Bioanalytical Chemistry 385:4, pages 716-723.
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Felicia B. Williams, Lane C. Sander, Stephen A. Wise & James Girard. (2006) Development and evaluation of methods for determination of naphthodianthrones and flavonoids in St. John's wort. Journal of Chromatography A 1115:1-2, pages 93-102.
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