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Research Article

A Rapid Method for the Isolation of Swertiamarin from Enicostemma littorale

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Pages 400-403 | Published online: 29 Sep 2008

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Read on this site (6)

Niraj Kumar, Nancy Tripathi, Sanjeev Kumar, Manoj Kushwaha, Chiranjib Banerjee & Swapan Dey. (2023) Mangiferin from Enicostemma littorale Blume with in silico and in vitro anti-inflammatory potential. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-10.
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Ashutosh Goswami, Bhakti Nanaware & Abhijeet S. Kate. (2023) Rapid and Efficient SpPRE Approach: A Step Towards Meeting High Demand of Bioactive Swertiamarin. Separation Science and Technology 58:9, pages 1607-1615.
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Sasidharan Perumal, MadhanaVigneshwari Gopal Samy & Dharaneedharan Subramanian. (2023) In vitro and in silico screening of novel typhoid drugs from endangered herb (Enicostema axillare). Journal of Biomolecular Structure and Dynamics 41:7, pages 2926-2936.
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Satyender Kumar, Prakash Niguram, Vedika Bhat, Seema Jinagal, Vinod Jairaj & Neelam Chauhan. (2022) Synthesis, molecular docking and ADMET prediction of novel swertiamarin analogues for the restoration of type-2 diabetes: an enzyme inhibition assay. Natural Product Research 36:9, pages 2197-2207.
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Dan Zhao, Rui Zhang, Xuemei Liu, Xiaoyun Li, Mengyu Xu, Xianju Huang & Xincai Xiao. (2022) Screening of Chitosan Derivatives-Carbon Dots Based on Antibacterial Activity and Application in Anti-Staphylococcus aureus Biofilm. International Journal of Nanomedicine 17, pages 937-952.
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Nur Sakinah Muhamad Fadzil, Mahendran Sekar, Siew Hua Gan, Srinivasa Reddy Bonam, Yuan Seng Wu, Jaishree Vaijanathappa, Subban Ravi, Pei Teng Lum & Shivsharan B Dhadde. (2021) Chemistry, Pharmacology and Therapeutic Potential of Swertiamarin – A Promising Natural Lead for New Drug Discovery and Development. Drug Design, Development and Therapy 15, pages 2721-2746.
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Articles from other publishers (26)

Madhana Vigneshwari Gopal Samy & Sasidharan Perumal. (2023) Systems pharmacology and multi-scale mechanism of Enicostema axillare bioactives in treating Alzheimer disease. Inflammopharmacology.
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Sonam Sharma. (2023) Pharmacological mechanism of indigenous herb Exacum lawii on cisplatin instigated toxicity in human embryonic kidney cells (HEK-293). Phytomedicine Plus 3:2, pages 100454.
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Monika Sharma, Fehmina Mushtaque Malim, Ashutosh Goswami, Nishant Sharma, Sai Sowmya Juvvalapalli, Sayan Chatterjee, Abhijeet S. Kate & Amit Khairnar. (2022) Neuroprotective Effect of Swertiamarin in a Rotenone Model of Parkinson’s Disease: Role of Neuroinflammation and Alpha-Synuclein Accumulation. ACS Pharmacology & Translational Science 6:1, pages 40-51.
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Sasidharan Perumal, MadhanaVigneshwari Gopal Samy & Dharaneedharan Subramanian. (2022) Effect of novel therapeutic medicine swertiamarin from Enicostema axillare in zebrafish infected with Salmonella typhi . Chemical Biology & Drug Design 100:6, pages 1033-1041.
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Altaf Khan, Aziz Unnisa, Mo Sohel, Mohan Date, Nayan Panpaliya, Shweta G. Saboo, Falak Siddiqui & Sharuk Khan. (2021) Investigation of phytoconstituents of Enicostemma littorale as potential glucokinase activators through molecular docking for the treatment of type 2 diabetes mellitus. In Silico Pharmacology 10:1.
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Sasidharan Perumal, Madhana Vigneshwari Gopal Samy & Dharaneedharan Subramanian. (2021) Selenium nanoparticle synthesis from endangered medicinal herb (Enicostema axillare). Bioprocess and Biosystems Engineering 44:9, pages 1853-1863.
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Kirti Parwani, Farhin Patel, Dhara Patel & Palash Mandal. (2021) Protective Effects of Swertiamarin against Methylglyoxal-Induced Epithelial-Mesenchymal Transition by Improving Oxidative Stress in Rat Kidney Epithelial (NRK-52E) Cells. Molecules 26:9, pages 2748.
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Jaishree Vaijanathappa, Jamuna Puttaswamygowda, Ramesh Bevanhalli, Sheshagiri Dixit & Prabitha Prabhakaran. (2020) Molecular docking, antiproliferative and anticonvulsant activities of swertiamarin isolated from Enicostemma axillare. Bioorganic Chemistry 94, pages 103428.
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Dragana Matekalo, Marijana Skorić, Tijana Nikolić, Lazar Novaković, Milana Lukić, Jelena Božunović, Neda Aničić, Biljana Filipović & Danijela Mišić. (2018) Organ-specific and genotype-dependent constitutive biosynthesis of secoiridoid glucosides in Centaurium erythraea Rafn, and its elicitation with methyl jasmonate. Phytochemistry 155, pages 69-82.
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Shani Raj, Suresh Chand Mali & Rohini Trivedi. (2018) Green synthesis and characterization of silver nanoparticles using Enicostemma axillare (Lam.) leaf extract. Biochemical and Biophysical Research Communications 503:4, pages 2814-2819.
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P. Sasidharan & A. Jayachitra. (2016) Direct shoot bud regeneration from shoot tip explants of Enicostema axillare: an important medicinal plant. Agroforestry Systems 91:3, pages 471-477.
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Tushar P. Patel, Komal Rawal, Sanket Soni & Sarita Gupta. (2016) Swertiamarin ameliorates oleic acid induced lipid accumulation and oxidative stress by attenuating gluconeogenesis and lipogenesis in hepatic steatosis. Biomedicine & Pharmacotherapy 83, pages 785-791.
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G. Dhanavathy. (2015) Immunohistochemistry, histopathology, and biomarker studies of swertiamarin, a secoiridoid glycoside, prevents and protects streptozotocin-induced β-cell damage in Wistar rat pancreas. Journal of Endocrinological Investigation 38:6, pages 669-684.
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Mohamed M. Shabi, Subashini Uthrapathy, Chellappan David Raj, Gayathri Krishnamoorthy, Dhevi Ravindhran, Jipnomon Joseph & Victor G. Rajamanickam. (2014) Analgesic and Anti-Arthritic Effect of <i>Enicostemma littorale</i> Blume. Advances in Bioscience and Biotechnology 05:13, pages 1018-1024.
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Tushar P. Patel, Sanket Soni, Pankti Parikh, Jeetendra Gosai, Ragitha Chruvattil & Sarita Gupta. (2013) Swertiamarin: An Active Lead from Enicostemma littorale Regulates Hepatic and Adipose Tissue Gene Expression by Targeting PPAR- γ and Improves Insulin Sensitivity in Experimental NIDDM Rat Model . Evidence-Based Complementary and Alternative Medicine 2013, pages 1-11.
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S. Saravanan, N. Prakash Babu, P. Pandikumar, M. Karunai Raj, M. Gabriel Paulraj & S. Ignacimuthu. (2012) Immunomodulatory potential of Enicostema axillare (Lam.) A. Raynal, a traditional medicinal plant. Journal of Ethnopharmacology 140:2, pages 239-246.
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Laxman Sawant, Bala Prabhakar & Nancy Pandita. (2011) A validated quantitative HPTLC method for analysis of biomarkers in Enicostemma littorale Blume . Journal of Planar Chromatography – Modern TLC 24:6, pages 497-502.
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Laxman Sawant, Bala Prabhakar & Nancy Pandita. (2011) HPTLC method for quantification of isovitexin in the whole-plant powder of Enicostemma littorale Blume . Journal of Planar Chromatography – Modern TLC 24:4, pages 301-305.
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Aiyalu Rajasekaran, Ramasamy Arivukkarasu & Shanmugasundaram Murugesh. (2010) Evaluation of antipyretic activity of ethyl acetate extract of Adenema hyssopifolium G. Don in a rat model. Asian Pacific Journal of Tropical Medicine 3:7, pages 523-526.
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V. Jaishree & Shrishailappa Badami. (2010) Antioxidant and hepatoprotective effect of swertiamarin from Enicostemma axillare against d-galactosamine induced acute liver damage in rats. Journal of Ethnopharmacology 130:1, pages 103-106.
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Rakesh D. Sonawane, Santosh L. Vishwakarma, S. Lakshmi, Mandapati Rajani, Harish Padh & Ramesh K. Goyal. (2010) Amelioration of STZ-induced type 1 diabetic nephropathy by aqueous extract of Enicostemma littorale Blume and swertiamarin in rats. Molecular and Cellular Biochemistry 340:1-2, pages 1-6.
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Hitesh Vaidya, Mandapati Rajani, Vasudevan Sudarsanam, Harish Padh & Ramesh Goyal. (2009) Antihyperlipidaemic activity of swertiamarin, a secoiridoid glycoside in poloxamer-407-induced hyperlipidaemic rats. Journal of Natural Medicines 63:4, pages 437-442.
Crossref
Hitesh Vaidya, Mandapati Rajani, Vasudevan Sudarsanam, Harish Padh & Ramesh Goyal. (2009) Swertiamarin: A lead from Enicostemma littorale Blume. for anti-hyperlipidaemic effect. European Journal of Pharmacology 617:1-3, pages 108-112.
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V. Jaishree, S. Badami, M. Rupesh Kumar & T. Tamizhmani. (2009) Antinociceptive activity of swertiamarin isolated from Enicostemma axillare. Phytomedicine 16:2-3, pages 227-232.
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Shahin Sharif Ali, Naresh Kasoju, Abhinav Luthra, Angad Singh, Hallihosur Sharanabasava, Abhishek Sahu & Utpal Bora. (2008) Indian medicinal herbs as sources of antioxidants. Food Research International 41:1, pages 1-15.
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Vihas T. Vasu, Hiren Modi, Jyoti V. Thaikoottathil & Sarita Gupta. (2005) Hypolipidaemic and antioxidant effect of Enicostemma littorale Blume aqueous extract in cholesterol fed rats. Journal of Ethnopharmacology 101:1-3, pages 277-282.
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