Advanced search
Publication Cover
Pharmaceutical Biology Volume 43, 2005 - Issue 6
Submit an article Journal homepage
853
Views
21
CrossRef citations to date
0
Altmetric
Research Article

Cytotoxic Activities of Major Diterpenoid Constituents of Andrographis paniculata. in a Panel of Human Tumor Cell Lines

M.L. Tan Advanced Medical and Dental Institute, EUREKA Complex, Universiti Sains Malaysia, Minden, Pulau Pinang, Malaysia
,
M. Kuroyanagi School of Bioresources, Hiroshima Prefectural University, Shobara-shi, Hiroshima, Japan
,
S.F. Sulaiman School of Biological Sciences, Universiti Sains Malaysia, Minden, Pulau Pinang, Malaysia
,
N. Najimudin School of Biological Sciences, Universiti Sains Malaysia, Minden, Pulau Pinang, Malaysia
&
T.S. Tengku Muhammad School of Biological Sciences, Universiti Sains Malaysia, Minden, Pulau Pinang, Malaysia
Pages 501-508 | Published online: 07 Oct 2008

Citations (21)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Sajad Fakhri, Fatemeh Abbaszadeh, Masoumeh Jorjani & Mohammad Hossein Pourgholami. (2021) The effects of anticancer medicinal herbs on vascular endothelial growth factor based on pharmacological aspects: a review study. Nutrition and Cancer 73:1, pages 1-15.
Read now
Abubakar Sule, Qamar Uddin Ahmed, Jalifah Latip, Othman Abd. Samah, Muhammad Nor Omar, Abdulrashid Umar & Bashar Bello S. Dogarai. (2012) Antifungal activity of Andrographis paniculata extracts and active principles against skin pathogenic fungal strains in vitro. Pharmaceutical Biology 50:7, pages 850-856.
Read now

Articles from other publishers (19)

Adhikesavan Harikrishnan, VijayKumar Veena, Roshini Kancharla, Sakshi Chavan, Jothi Ramalingam Rajabathar, Hamad Al-Lohedan, Saravanan Pandiaraj, Ponmurugan Karuppiah & Selvaraj Arokiyaraj. (2023) Anti-breast cancer activity of bioactive metabolites from Andrographis paniculata through inhibition of PI3K activity in triple negative breast cancer (MDA-MB-231) cells. Journal of Molecular Structure 1294, pages 136506.
Crossref
Sunil Kumar, Bikarma Singh & Vikas Bajpai. (2021) Andrographis paniculata (Burm.f.) Nees: Traditional uses, phytochemistry, pharmacological properties and quality control/quality assurance. Journal of Ethnopharmacology 275, pages 114054.
Crossref
François Chassagne, Mohamed Haddad, Aurélien Amiel, Chiobouaphong Phakeovilay, Chanthanom Manithip, Geneviève Bourdy, Eric Deharo & Guillaume Marti. (2018) A metabolomic approach to identify anti-hepatocarcinogenic compounds from plants used traditionally in the treatment of liver diseases. Fitoterapia 127, pages 226-236.
Crossref
Sudarat Sombut, Rada Bunthawong, Uthaiwan Sirion, Teerapich Kasemsuk, Pawinee Piyachaturawat, Kanoknetr Suksen, Apichart Suksamrarn & Rungnapha Saeeng. (2017) Synthesis of 14-deoxy-11,12-didehydroandrographolide analogues as potential cytotoxic agents for cholangiocarcinoma. Bioorganic & Medicinal Chemistry Letters 27:23, pages 5139-5143.
Crossref
Heng Kean Tan, Tengku Sifzizul Tengku Muhammad & Mei Lan Tan. (2016) 14-Deoxy-11,12-didehydroandrographolide induces DDIT3-dependent endoplasmic reticulum stress-mediated autophagy in T-47D breast carcinoma cells. Toxicology and Applied Pharmacology 300, pages 55-69.
Crossref
Deepti Arha, Sukanya Pandeti, Akansha Mishra, Swayam Prakash Srivastava, Arvind Kumar Srivastava, Tadigoppula Narender & Akhilesh Kumar Tamrakar. (2015) Deoxyandrographolide promotes glucose uptake through glucose transporter-4 translocation to plasma membrane in L6 myotubes and exerts antihyperglycemic effect in vivo. European Journal of Pharmacology 768, pages 207-216.
Crossref
Elfahmi, Herman J. Woerdenbag & Oliver Kayser. (2014) Jamu: Indonesian traditional herbal medicine towards rational phytopharmacological use. Journal of Herbal Medicine 4:2, pages 51-73.
Crossref
Rahul Raghavan, Sanith Cheriyamundath & Joseph Madassery. (2014) 14-Deoxy-11,12-didehydroandrographolide inhibits proliferation and induces GSH-dependent cell death of human promonocytic leukemic cells. Journal of Natural Medicines 68:2, pages 387-394.
Crossref
Samir Mandal, Sibabrata Mukhopadhyay, Sukdeb Bandhopadhyay, Gargi Sen & Tuli Biswas. (2014) 14-Deoxyandrographolide alleviates ethanol-induced hepatosteatosis through stimulation of AMP-activated protein kinase activity in rats. Alcohol 48:2, pages 123-132.
Crossref
Md. Sanower Hossain, Zannat Urbi, Abubakar Sule & K. M. Hafizur Rahman. (2014) Andrographis paniculata (Burm. f.) Wall. ex Nees: A Review of Ethnobotany, Phytochemistry, and Pharmacology . The Scientific World Journal 2014, pages 1-28.
Crossref
Samir Mandal, Vinod K. Nelson, Sibabrata Mukhopadhyay, Sukdeb Bandhopadhyay, Lakshmi Maganti, Nanda Ghoshal, Gargi Sen & Tuli Biswas. (2013) 14-Deoxyandrographolide targets adenylate cyclase and prevents ethanol-induced liver injury through constitutive NOS dependent reduced redox signaling in rats. Food and Chemical Toxicology 59, pages 236-248.
Crossref
R Krithika, RJ Verma & PS Shrivastav. (2012) Antioxidative and cytoprotective effects of andrographolide against CCl 4 -induced hepatotoxicity in HepG2 cells . Human & Experimental Toxicology 32:5, pages 530-543.
Crossref
Rammohan Subramanian, Mohd. Zaini Asmawi & Amirin Sadikun. (2011) A bitter plant with a sweet future? A comprehensive review of an oriental medicinal plant: Andrographis paniculata. Phytochemistry Reviews 11:1, pages 39-75.
Crossref
Mei Lan Tan, Heng Kean Tan, Chern Ein Oon, Masanori Kuroyanagi & Tengku Sifzizul Tengku Muhammad. (2012) Identification of genes involved in the regulation of 14-deoxy-11,12-didehydroandrographolide-induced toxicity in T-47D mammary cells. Food and Chemical Toxicology 50:2, pages 431-444.
Crossref
Shou-Ping Guan, Li-Ren Kong, Chang Cheng, Jonathan C. W. Lim & W. S. Fred Wong. (2011) Protective Role of 14-Deoxy-11,12-didehydroandrographolide, a Noncytotoxic Analogue of Andrographolide, in Allergic Airway Inflammation. Journal of Natural Products 74:6, pages 1484-1490.
Crossref
Jer Ping Ooi, Masanori Kuroyanagi, Shaida Fariza Sulaiman, Tengku Sifzizul Tengku Muhammad & Mei Lan Tan. (2011) Andrographolide and 14-Deoxy-11, 12-Didehydroandrographolide inhibit cytochrome P450s in HepG2 hepatoma cells. Life Sciences 88:9-10, pages 447-454.
Crossref
DN Roy, S Mandal, G Sen, S Mukhopadhyay & T Biswas. (2010) 14‐Deoxyandrographolide desensitizes hepatocytes to tumour necrosis factor‐alpha‐induced apoptosis through calcium‐dependent tumour necrosis factor receptor superfamily member 1A release via the NO/cGMP pathway. British Journal of Pharmacology 160:7, pages 1823-1843.
Crossref
Zhi Gang Chen, Ren Xiang Tan & Lin Cao. (2009) Efficient and highly regioselective acylation of andrographolide catalyzed by lipase in acetone. Green Chemistry 11:11, pages 1743.
Crossref
Madamanchi Geethangili, Yerra Koteswara Rao, Shih‐Hua Fang & Yew‐Min Tzeng. (2008) Cytotoxic constituents from Andrographis paniculata induce cell cycle arrest in jurkat cells . Phytotherapy Research 22:10, pages 1336-1341.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.