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Research Article

Terpenoids of Sinularia.: Chemistry and Biomedical Applications

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Pages 253-269 | Accepted 29 Dec 2004, Published online: 07 Oct 2008

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Yi Li & Gerald Pattenden. (2011) Biomimetic syntheses of ineleganolide and sinulochmodin C from 5-episinuleptolide via sequences of transannular Michael reactions. Tetrahedron 67:51, pages 10045-10052.
Crossref
Alec Saitman, Pauline Rulliere, Steven D. E. Sullivan & Emmanuel A. Theodorakis. (2011) Total Synthesis of Norcembrenolide B and Scabrolide D. Organic Letters 13:21, pages 5854-5857.
Crossref
Daowan Lai, Yongxin Li, Minjuan Xu, Zhiwei Deng, Leen van Ofwegen, Peiyuan Qian, Peter Proksch & Wenhan Lin. (2011) Sinulariols A–S, 19-oxygenated cembranoids from the Chinese soft coral Sinularia rigida. Tetrahedron 67:33, pages 6018-6029.
Crossref
Yi Li & Gerald Pattenden. (2011) Perspectives on the structural and biosynthetic interrelationships between oxygenated furanocembranoids and their polycyclic congeners found in corals. Natural Product Reports 28:7, pages 1269.
Crossref
Yi Li & Gerald Pattenden. (2011) Novel macrocyclic and polycyclic norcembranoid diterpenes from Sinularia species of soft coral: Structural relationships and biosynthetic speculations. Natural Product Reports 28:2, pages 429.
Crossref
Yan Li, Marianna Carbone, Rosa Maria Vitale, Pietro Amodeo, Francesco Castelluccio, Giovanna Sicilia, Ernesto Mollo, Michela Nappo, Guido Cimino, Yue-Wei Guo & Margherita Gavagnin. (2010) Rare Casbane Diterpenoids from the Hainan Soft Coral Sinularia depressa . Journal of Natural Products 73:2, pages 133-138.
Crossref
Shi-Yie Cheng, Ki-Jhih Huang, Shang-Kwei Wang, Zhi-Horng Wen, Chi-Hsin Hsu, Chang-Feng Dai & Chang-Yih Duh. (2009) New Terpenoids from the Soft Corals Sinularia capillosa and Nephthea chabroli . Organic Letters 11:21, pages 4830-4833.
Crossref
Mohammad K. Khalesi. (2008) Cell cultures from the symbiotic soft coral Sinularia flexibilis. In Vitro Cellular & Developmental Biology - Animal 44:8-9, pages 330-338.
Crossref
Marc Slattery, Haidy N. Kamel, Sridevi Ankisetty, Deborah J. Gochfeld, Cindi A. Hoover & Robert W. Thacker. (2008) HYBRID VIGOR IN A TROPICAL PACIFIC SOFT-CORAL COMMUNITY. Ecological Monographs 78:3, pages 423-443.
Crossref
Mohamed M. Radwan, Susan P. Manly, Khalid A. El Sayed, Vikram B. Wali, Paul W. Sylvester, Bhushan Awate, Girish Shah & Samir A. Ross. (2008) Sinulodurins A and B, Antiproliferative and Anti-invasive Diterpenes from the Soft Coral Sinularia dura . Journal of Natural Products 71:8, pages 1468-1471.
Crossref
Cindi A. Hoover, Marc Slattery, Nancy M. Targett & Adam G. Marsh. (2008) Transcriptome and Metabolite Responses to Predation in a South Pacific Soft Coral. The Biological Bulletin 214:3, pages 319-328.
Crossref
Paul A. Roethle & Dirk Trauner. (2008) The chemistry of marine furanocembranoids, pseudopteranes, gersolanes, and related natural products. Natural Product Reports 25:2, pages 298.
Crossref
Mohammad K. Khalesi, H.H. Beeftink & R.H. Wijffels. (2007) Flow-dependent growth in the zooxanthellate soft coral Sinularia flexibilis. Journal of Experimental Marine Biology and Ecology 351:1-2, pages 106-113.
Crossref
Haidy Nasr Kamel, Daneel Ferreira, Luis F. Garcia-Fernandez & Marc Slattery. (2007) Cytotoxic Diterpenoids from the Hybrid Soft Coral Sinularia maxima × Sinularia polydactyla . Journal of Natural Products 70:8, pages 1223-1227.
Crossref
John W. Blunt, Brent R. Copp, Wan-Ping Hu, Murray H. G. Munro, Peter T. Northcote & Mich?le R. Prinsep. (2007) Marine natural products. Natural Product Reports 24:1, pages 31.
Crossref
Bernard Tursch. (1976) Some Recent Developments in the Chemistry of Alcyonaceans. Pure and Applied Chemistry 48:1, pages 1-6.
Crossref

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