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Pharmaceutical Biology Volume 46, 2008 - Issue 3
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Research Article

Cytotoxic Activity of Some Anatolian Salvia. Extracts and Isolated Abietane Diterpenoids

G. Topcu Istanbul University, Faculty of Pharmacy, Beyazit-Istanbul, Turkey
,
Z. Turkmen Istanbul University, Faculty of Pharmacy, Beyazit-Istanbul, Turkey
,
J. K. Schilling Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA
,
D. G. I. Kingston Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA
,
J. M. Pezzuto College of Pharmacy, University of Hawaii at Hilo, Hilo, Hawaii, USA
&
A. Ulubelen Istanbul University, Faculty of Pharmacy, Beyazit-Istanbul, Turkey
Pages 180-184 | Accepted 01 Aug 2008, Published online: 07 Oct 2008

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Amal M. El-Feky, Marwa M. Elbatanony, Asmaa F. Aboul Naser, Eman A. Younis & Manal A. Hamed. (2022) Salvia hispanica L. seeds extract alleviate encephalopathy in streptozotocin-induced diabetes in rats: role of oxidative stress, neurotransmitters, DNA and histological indices. Biomarkers 27:5, pages 427-440.
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Yusuf Ozay, Sevda Guzel, Ebru Gokalp Ozkorkmaz, Meltem Kumas, Cosar Uzun, Zuhal Yıldırım, Ayla Celik, Yusuf Camlıca, Onder Yumrutas, Gizem Guler, Nurten Erdal, Bahar Tasdelen, Havva Didem Celikcan & Ahmet Kahraman. (2021) Biochemical, Histopathologic, and Genotoxic Effects of Ethanol Extract of Salvia hypargeia (Fisch. & Mey.) on Incisional and Excisional Wounded Diabetic Rats. Journal of Investigative Surgery 34:1, pages 7-19.
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Xiaozhi Peng, Yijun Tu, San Fu, Yu Xia, Chaozhi Ma, Yanfang Yang, Hezhen Wu, Yanwen Liu & Pengtao You. (2019) 14-Deoxycoleon U-induced endoplasmic reticulum stress-mediated apoptosis, autophagy, and cell cycle arrest in lung adenocarcinoma. OncoTargets and Therapy 12, pages 5955-5965.
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Yuanyuan Jiang, Li Zhang & HP Vasantha Rupasinghe. (2016) The anticancer properties of phytochemical extracts from Salvia plants. Botanics: Targets and Therapy 6, pages 25-44.
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Ali Karagöz, Fulya T. Artun, Gül Özcan, Gülay Melikoğlu, Sezin Anıl, Şükran Kültür & Nurhayat Sütlüpınar. (2015) In vitro evaluation of antioxidant activity of some plant methanol extracts. Biotechnology & Biotechnological Equipment 29:6, pages 1184-1189.
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Hala I. Al-Jaber, Mahmoud A. Al-Qudah, Lina M. Barhoumi, Ismail F. Abaza & Fatma U. Afifi. (2012) Essential oil composition of the aerial parts of fresh and air-dried Salvia palaestina Benth. (Lamiaceae) growing wild in Jordan. Natural Product Research 26:13, pages 1179-1187.
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Somayyeh Gandomkar, Maryam Yousefi, Zohreh Habibi & Mohammad Ali As’habi. (2012) A new triterpene from Salvia xanthocheila Boiss.. Natural Product Research 26:7, pages 648-653.
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Sevgi Irtegun Kandemir, Hilal Saruhan Fidan, Ismail Yener, Nuriye Mete, Abdulselam Ertas, Gulactı Topcu & Ufuk Kolak. (2022) Investigation of cytotoxic and apoptotic effects of 63 compounds obtained from Salvia species: Promising anticancer agents . Journal of Food Biochemistry 46:9.
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Gökçe Şeker Karatoprak, Fatih Göger, İsmail Çelik, Ümit Budak, Esra Küpeli Akkol & Michael Aschner. (2022) Phytochemical profile, antioxidant, antiproliferative, and enzyme inhibition-docking analyses of Salvia ekimiana Celep & Doğan. South African Journal of Botany 146, pages 36-47.
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Sevda GÜZEL. (2020) Bolivya’da yetişen Chia (Salvia hispanica L.) tohumlarının yağ asidi, sterol, tokoferol ve mineral kompozisyonları; toplam fenol ve flavonoit miktarları ve antioksidan aktivitesiFatty acid, sterol, tocopherol, and mineral compositions; total phenolic and flavonoid contents and antioxidant activity of Chia (Salvia hispanica L.) seeds growing in Bolivia. Mersin Üniversitesi Sağlık Bilimleri Dergisi 13:3, pages 428-436.
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Ahmet Kahraman, Hatice Nurhan BÜYÜKKARTAL & Musa Doğan. (2018) Pericarp Ultrastructure of Salvia Section Hemisphace (Mentheae; Nepetoideae; Lamiaceae). Commagene Journal of Biology -:-, pages 1-7.
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Lamia Benniou, Moses K. Langat, Dulcie A. Mulholland, Fadila Benayache & Samir Benayache. (2018) Oleanane triterpenoids from the Algerian Salvia phlomoides. Phytochemistry Letters 24, pages 136-139.
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Nimsi Campos-Xolalpa, Salud Pérez-Gutiérrez, Cuauhtémoc Pérez-González, Julia Mendoza-Pérez & Angel Josabad Alonso-Castro. 2018. Anticancer Plants: Natural Products and Biotechnological Implements. Anticancer Plants: Natural Products and Biotechnological Implements 163 205 .
Gülaçtı Topçu, Rümeysa Yücer & Halil Şenol. 2017. Salvia Biotechnology. Salvia Biotechnology 31 132 .
Amir Reza Jassbi, Somayeh Zare, Omidreza Firuzi & Jianbo Xiao. (2015) Bioactive phytochemicals from shoots and roots of Salvia species. Phytochemistry Reviews 15:5, pages 829-867.
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Miguel A. González. (2015) Aromatic abietane diterpenoids: their biological activity and synthesis. Natural Product Reports 32:5, pages 684-704.
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Lin-zhen Li, Meng-hua Wang, Jian-bo Sun & Jing-yu Liang. (2014) Abietane diterpenoids and other constituents from Clerodendrum trichotomum. Biochemical Systematics and Ecology 56, pages 218-220.
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Zahra Tayarani-Najaran, Seyed Hadi Mousavi, Faezeh Tajfard, Javad Asili, Saba Soltani, Mahdi Hatamipour & Seyed Ahmad Emami. (2013) Cytotoxic and apoptogenic properties of three isolated diterpenoids from Salvia chorassanica through bioassay-guided fractionation. Food and Chemical Toxicology 57, pages 346-351.
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Gábor Janicsák, István Zupkó, Milena T. Nikolova, Peter Forgo, Andrea Vasas, Imre Máthé, Gerald Blunden & Judit Hohmann. (2011) Bioactivity-guided Study of Antiproliferative Activities of Salvia Extracts . Natural Product Communications 6:5, pages 1934578X1100600.
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Niko Radulović, Marija Denić & Zorica Stojanović-Radić. (2010) Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae). Bioorganic & Medicinal Chemistry Letters 20:17, pages 4988-4991.
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Nevin Öztekin, Selda Başkan, S. Evrim Kepekçi, F. Bedia Erim & Gülaçtı Topçu. (2010) Isolation and analysis of bioactive diterpenoids in Salvia species (Salvia chionantha and Salvia kronenburgiii) by micellar electrokinetic capillary chromatography. Journal of Pharmaceutical and Biomedical Analysis 51:2, pages 439-442.
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Nada Babovic, Sonja Djilas, Milka Jadranin, Vlatka Vajs, Jasna Ivanovic, Slobodan Petrovic & Irena Zizovic. (2010) Supercritical carbon dioxide extraction of antioxidant fractions from selected Lamiaceae herbs and their antioxidant capacity. Innovative Food Science & Emerging Technologies 11:1, pages 98-107.
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Gülaçti Topçu, Gülendam Tümen, Turgut Kiliç, Ahmet C. GÖren, Asli Barla, Zeynep Türkmen & David G. I. Kingston. 2009. Innovations in Chemical Biology. Innovations in Chemical Biology 61 81 .

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