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Pharmaceutical Biology Volume 56, 2018 - Issue 1

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Review Article

Echinacea biotechnology: advances, commercialization and future considerations

Jessica L. ParsonsOttawa-Carleton Institute of Biology, Ottawa, ON, Canada; ;Department of Biology, Carleton University, Ottawa, ON, Canada; View further author information

Stewart I. CameronWood Science and Technology Centre, Hugh John Flemming Forestry Centre, Fredericton, NB, Canada; View further author information

Cory S. HarrisOttawa-Carleton Institute of Biology, Ottawa, ON, Canada; ;Department of Biology, University of Ottawa, Ottawa, ON, CanadaCorrespondence[email protected]
View further author information

Myron L. SmithOttawa-Carleton Institute of Biology, Ottawa, ON, Canada; ;Department of Biology, Carleton University, Ottawa, ON, Canada; Correspondence[email protected]

http://orcid.org/0000-0001-6274-0053 View further author information

Pages 485-494 | Received 27 Mar 2018, Accepted 14 Jul 2018, Published online: 10 Oct 2018

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https://doi.org/10.1080/13880209.2018.1501583
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Liesbeth B. M. Veldman, Eefje Belt-Van Zoen & Erik W. Baars. (2023) Mechanistic Evidence of Andrographis paniculata (Burm. f.) Wall. ex Nees, Pelargonium sidoides DC., Echinacea Species and a Combination of Hedera helix L., Primula veris L./Primula elatior L. and Thymus vulgaris L./Thymus zygis L. in the Treatment of Acute, Uncomplicated Respiratory Tract Infections: A Systematic Literature Review and Expert Interviews. Pharmaceuticals 16:9, pages 1206.
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M. Alamholo & J. Soltani. (2023) Agrobacterium rhizogenes-Mediated Transformation as a Means for Induction of Hairy Roots and Secondary Metabolites in Thymus daenensis. Biology Bulletin 50:4, pages 621-627.
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E. A. Kalashnikova, R. N. Kirakosyan, V. I. Trukhachev, M. G. Pankova & A. V. Sumin. (2023) Features of Growth and Inulin Content in Callus Cultures Cichorium intybus L. In Vitro. Russian Journal of Plant Physiology 70:4.
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Janusz Malarz, Yulia V. Yudina & Anna Stojakowska. (2023) Hairy Root Cultures as a Source of Phenolic Antioxidants: Simple Phenolics, Phenolic Acids, Phenylethanoids, and Hydroxycinnamates. International Journal of Molecular Sciences 24:8, pages 6920.
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Fatemeh RASOLİ & Manoochehr GHOLİPOOR. (2023) Interactive effects of salicylic acid and jasmonic acid on secondary metabolite production in Echinacea purpureaInteractive effects of salicylic acid and jasmonic acid on secondary metabolite production in Echinacea purpurea. International Journal of Secondary Metabolite 10:1, pages 106-118.
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Mihir Kumar Purkait, Dibyajyoti Haldar & Prangan Duarah. 2023. Advances in Extraction and Applications of Bioactive Phytochemicals. Advances in Extraction and Applications of Bioactive Phytochemicals 29 53 .

Tunhan Demirci. (2022) Determination of secondary metabolite production efficiency in Echinacea purpurea callus, shoot, and root in vitro cultures with methyl jasmonate applications. Acta Physiologiae Plantarum 44:12.
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Rima N. Kirakosyan, Anton V. Sumin, Anna A. Polupanova, Maria G. Pankova, Irina S. Degtyareva, Nikolay N. Sleptsov & Quyet V. Khuat. (2022) Influence of Plant Growth Regulators and Artificial Light on the Growth and Accumulation of Inulin of Dedifferentiated Chicory (Cichorium intybus L.) Callus Cells. Life 12:10, pages 1524.
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Laura Ravazzolo, Benedetto Ruperti, Marco Frigo, Oriana Bertaiola, Giovanna Pressi, Mario Malagoli & Silvia Quaggiotti. (2022) C3H Expression Is Crucial for Methyl Jasmonate Induction of Chicoric Acid Production by Echinacea purpurea (L.) Moench Cell Suspension Cultures. International Journal of Molecular Sciences 23:19, pages 11179.
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Archana Prasad, Preeti Patel, Abhishek Niranjan, Aradhana Mishra, Gauri Saxena, Satya Shila Singh & Debasis Chakrabarty. (2022) Biotic elicitor–induced changes in growth, antioxidative defense, and metabolites in an improved prickleless Solanum viarum. Applied Microbiology and Biotechnology.
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Bahareh Hajirostamloo & Mohammad Molaveisi. (2022) Active Alyssum homolocarpum seed gum films containing microencapsulated Echinacea purpurea (L.) extract; study of physicochemical properties and its application in quail meat packaging. Journal of Food Measurement and Characterization 16:3, pages 1997-2010.
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Masooma Jawad Hussain, Yawar Abbas, Naushaba Nazli, Sara Fatima, Samantha Drouet, Christophe Hano & Bilal Haider Abbasi. (2022) Root Cultures, a Boon for the Production of Valuable Compounds: A Comparative Review. Plants 11:3, pages 439.
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Monika Michalak. (2022) Plant-Derived Antioxidants: Significance in Skin Health and the Ageing Process. International Journal of Molecular Sciences 23:2, pages 585.
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Can Celiloğlu, Ümit Çelik & Fatma Levent. 2022. Pediatric ENT Infections. Pediatric ENT Infections 1053 1061 .

Rao Fu, Pingyu Zhang, Zongbi Deng, Ge Jin & Yang Zhang. (2021) Chicoric acid provides better ultraviolet protection than the sum of its substrates in purple coneflower plants. Industrial Crops and Products 170, pages 113778.
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Elizaveta Mikhailovna Ipanova, Daria Viktorovna Zarembo & Dmitriy Nikolayevich Vedernikov. (2021) INCREASE IN THE YIELD OF CINNAMIC ACIDS DERIVATIVES FROM ECHINACEA AS A RESULT OF WEAK ACOUSTIC EFFECTS. chemistry of plant raw material:2, pages 327-331.
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Khawla Omran Mohamed Sharif, Enis Fuat Tufekci, Buket Ustaoglu, Yasemin Celik Altunoglu, Gokhan Zengin, E.J. Llorent-Martínez, Kerim Guney & Mehmet Cengiz Baloglu. (2021) Anticancer and biological properties of leaf and flower extracts of Echinacea purpurea (L.) Moench. Food Bioscience 41, pages 101005.
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Charles Awortwe, Henrike Bruckmueller, Meike Kaehler & Ingolf Cascorbi. (2021) Interaction of Phytocompounds of Echinacea purpurea with ABCB1 and ABCG2 Efflux Transporters . Molecular Pharmaceutics 18:4, pages 1622-1633.
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Sara M. Handy, Rahul S. Pawar, Andrea R. Ottesen, Padmini Ramachandran, Satyanarayanaraju Sagi, Ning Zhang, Erica Hsu & David L. Erickson. (2021) HPLC-UV, Metabarcoding and Genome Skims of Botanical Dietary Supplements: A Case Study in Echinacea. Planta Medica 87:04, pages 314-324.
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Fatemeh Ahmadi, Abbas Samadi, Ebrahim Sepehr, Amir Rahimi & Sergey Shabala. (2021) Perlite particle size and NO3-/NH4+ ratio affect growth and chemical composition of purple coneflower (Echinacea purpurea L.) in hydroponics. Industrial Crops and Products 162, pages 113285.
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Geraldine Gubser, Sabine Vollenweider, Dieter Eibl & Regine Eibl. (2021) Food ingredients and food made with plant cell and tissue cultures: State‐of‐the art and future trends. Engineering in Life Sciences 21:3-4, pages 87-98.
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M.F. Nagoor Meeran, Hayate Javed, Charu Sharma, Sameer N. Goyal, Sanjay Kumar, Niraj Kumar Jha & Shreesh Ojha. (2021) Can Echinacea be a potential candidate to target immunity, inflammation, and infection - The trinity of coronavirus disease 2019. Heliyon 7:2, pages e05990.
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Grazhina V. Nester & Tatyana I. Ditchenko. (2020) Stimulation of phenolic nature secondary metabolites biosynthesis in Echinacea purpurea L. Moench suspension cell cultures under influence yeast extract elisitors. Journal of the Belarusian State University. Biology:2, pages 37-48.
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József Haller, Laszlo Krecsak & János Zámbori. (2019) Double‐blind placebo controlled trial of the anxiolytic effects of a standardized Echinacea extract. Phytotherapy Research 34:3, pages 660-668.
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Ilia Bresesti, Michela Ricci, Francesco Cerritelli, Angela Veneziano, Gianvincenzo Zuccotti & Gianluca Lista. (2019) Comparison between two ocular cleansing modalities in a population of newborns admitted to Neonatal Intensive Care Unit with clinical signs of conjunctivitis: a randomized controlled trial. Minerva Pediatrica 71:6.
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Ahmad Tahmasebi, Esmaeil Ebrahimie, Hassan Pakniyat, Mansour Ebrahimi & Manijeh Mohammadi-Dehcheshmeh. (2019) Insights from the Echinacea purpurea (L.) Moench transcriptome: Global reprogramming of gene expression patterns towards activation of secondary metabolism pathways. Industrial Crops and Products 132, pages 365-376.
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