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Pharmaceutical Biology Volume 57, 2019 - Issue 1
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Research Article

Ursolic acid inhibits epithelial-mesenchymal transition in vitro and in vivo

Chang-Geng XuDepartment of Urology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Correspondence[email protected]
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,
Xia-Lian ZhuDepartment of Hand Surgery, Affiliated Nanhua Hospital of University of South China, Hengyang, China; View further author information
,
Wei WangDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China; View further author information
&
Xiang-Jun ZhouDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, ChinaView further author information
Pages 169-175 | Received 31 Aug 2018, Accepted 28 Dec 2018, Published online: 24 Mar 2019

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Zhaohui Jia, Wensheng Li, Pan Bian, Liuyang Yang, Hui Liu, Dong Pan & Zhongling Dou. (2021) Ursolic acid treats renal tubular epithelial cell damage induced by calcium oxalate monohydrate via inhibiting oxidative stress and inflammation. Bioengineered 12:1, pages 5450-5461.
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Mingxiang Cao, Di Xiao & Xubei Ding. (2020) The anti-tumor effect of ursolic acid on papillary thyroid carcinoma via suppressing Fibronectin-1. Bioscience, Biotechnology, and Biochemistry 84:12, pages 2415-2424.
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Zhaohui Wang, Zhi Chen, Bingsheng Li, Bo Zhang, Yongchao Du, Yuhang Liu, Yao He & Xiang Chen. (2020) Curcumin attenuates renal interstitial fibrosis of obstructive nephropathy by suppressing epithelial-mesenchymal transition through inhibition of the TLR4/NF-кB and PI3K/AKT signalling pathways. Pharmaceutical Biology 58:1, pages 828-837.
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Articles from other publishers (7)

Sudarat Hadpech & Visith Thongboonkerd. (2023) Epithelial–mesenchymal plasticity in kidney fibrosis. genesis.
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Mohamed Mohany, Mohammed M. Ahmed & Salim S. Al-Rejaie. (2021) Molecular Mechanistic Pathways Targeted by Natural Antioxidants in the Prevention and Treatment of Chronic Kidney Disease. Antioxidants 11:1, pages 15.
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Jia-Lu Zheng, Shuang-Shuang Wang, Ke-Ping Shen, Lei Chen, Xiao Peng, Jin-Fang Chen, Hong-Mei An & Bing Hu. (2021) Ursolic acid induces apoptosis and anoikis in colorectal carcinoma RKO cells. BMC Complementary Medicine and Therapies 21:1.
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Rishila Ghosh, Manushi Siddarth, Pawan Kumar Kare, Basu Dev Banerjee, Om Prakash Kalra & Ashok Kumar Tripathi. (2021) β‐Endosulfan‐mediated induction of pro‐fibrotic markers in renal ( HK ‐2) cells in vitro : A new insight in the pathogenesis of chronic kidney disease of unknown etiology . Environmental Toxicology 36:11, pages 2354-2360.
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Huan Xu, Tianyi Wu & Leaf Huang. (2021) Therapeutic and delivery strategies of phytoconstituents for renal fibrosis. Advanced Drug Delivery Reviews 177, pages 113911.
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Lijun Zhang, Xiaohua Liu, Jun Liang, Jianhua Wu, Daqing Tan & Wei Hu. (2020) Lefty-1 inhibits renal epithelial–mesenchymal transition by antagonizing the TGF-β/Smad signaling pathway. Journal of Molecular Histology 51:1, pages 77-87.
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Ke Zhu, Cuixiang Cao, Jiaqi Huang, Zixuan Cheng, Donghai Li, Xiuting Liu, Yueping Mao & Qing Qi. (2019) Inhibitory effects of ursolic acid from Bushen Yijing Formula on TGF-β1-induced human umbilical vein endothelial cell fibrosis via AKT/mTOR signaling and Snail gene. Journal of Pharmacological Sciences 140:1, pages 33-42.
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