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Human Fertility
an international, multidisciplinary journal dedicated to furthering research and promoting good practice
Volume 20, 2017 - Issue 4
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Original Articles

Double ovarian stimulation (DuoStim) protocol for fertility preservation in female oncology patients

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Pages 248-253 | Received 26 Nov 2015, Accepted 22 Aug 2016, Published online: 09 Feb 2017

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Sarah J. Puthur, Susan Tracey, Della Gould & Cheryl T. Fitzgerald. (2023) DuoStim protocol- a novel fertility preservation strategy for female oncology patients. Human Fertility 0:0, pages 1-7.
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Gustavo N. Cecchino, Matheus Roque, María Cerrillo, Rodrigo da Rosa Filho, Flavia da Silva Chiamba, Juliana Halley Hatty & Juan A. García-Velasco. (2021) DuoStim cycles potentially boost reproductive outcomes in poor prognosis patients. Gynecological Endocrinology 37:6, pages 519-522.
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Alberto Vaiarelli, Danilo Cimadomo, Cecilia Petriglia, Alessandro Conforti, Carlo Alviggi, Nicolò Ubaldi, Sergio Ledda, Susanna Ferrero, Laura Rienzi & Filippo Maria Ubaldi. (2020) DuoStim – a reproducible strategy to obtain more oocytes and competent embryos in a short time-frame aimed at fertility preservation and IVF purposes. A systematic review. Upsala Journal of Medical Sciences 125:2, pages 121-130.
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Articles from other publishers (41)

Alberto Vaiarelli, Diego Domenico Fasulo, Danilo Cimadomo, Laura Rienzi & Filippo Maria Ubaldi. 2024. Handbook of Current and Novel Protocols for the Treatment of Infertility. Handbook of Current and Novel Protocols for the Treatment of Infertility 151 159 .
Marnie Slonim, Michelle Peate, Kira Merigan, Daniel Lantsberg, Richard A. Anderson, Kate Stern, Debra Gook & Yasmin Jayasinghe. (2023) Ovarian stimulation and oocyte cryopreservation in females and transgender males aged 18 years or less: a systematic review. Frontiers in Endocrinology 14.
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Pasquale Petrone, Alberto Vaiarelli & Christophe Blockeel. (2023) Double stimulation for the management of poor-prognosis patients: where are we going?. Current Opinion in Obstetrics & Gynecology 35:3, pages 246-253.
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Eric Han & David B. Seifer. (2023) Oocyte Cryopreservation for Medical and Planned Indications: A Practical Guide and Overview. Journal of Clinical Medicine 12:10, pages 3542.
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Maria G. Razeti, Davide Soldato, Luca Arecco, Alessia Levaggi, Silvia Puglisi, Cinzia Solinas, Elisa Agostinetto, Stefano Spinaci, Laura Lapuchesky, Carlo Genova, Claudia Massarotti & Matteo Lambertini. (2023) Approaches to Fertility Preservation for Young Women With Breast Cancer. Clinical Breast Cancer 23:3, pages 241-248.
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Angelo Tocci, David Barad, Krzysztof Łukaszuk & Raoul Orvieto. (2023) Routine double-ovarian-stimulation (DuoStim) in poor responders lacks rationale, evidence, and follow-up. Human Reproduction 38:3, pages 329-333.
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Clare Meernik, Stephanie M. Engel, Christopher D. Baggett, Ally Wardell, Xi Zhou, Kathryn J. Ruddy, Ethan Wantman, Valerie L. Baker, Barbara Luke, Jennifer E. Mersereau, Jianwen Cai, Andrew F. Olshan, Andrew B. Smitherman & Hazel B. Nichols. (2022) Time to cancer treatment and reproductive outcomes after fertility preservation among adolescent and young adult women with cancer. Cancer 129:2, pages 307-319.
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Konstantinos Dafopoulos & Basil C. Tarlatzis. 2023. Management of Infertility. Management of Infertility 199 204 .
Marta Caretto & Tommaso Simoncini. 2023. Amenorrhea. Amenorrhea 133 155 .
Hiroki Takeuchi, Tadashi Maezawa, Katsuyuki Hagiwara, Yuki Horage, Tetsuro Hanada, Huang Haipeng, Mito Sakamoto, Mikiko Nishioka, Erina Takayama, Kento Terada, Eiji Kondo, Yasushi Takai, Nao Suzuki & Tomoaki Ikeda. (2023) Investigation of an efficient method of oocyte retrieval by dual stimulation for patients with cancer. Reproductive Medicine and Biology 22:1.
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Marine Poulain, Jessica Vandame, Chloé Tran, Sonia Koutchinsky, Paul Pirtea & Jean-Marc Ayoubi. (2022) Fertility preservation in borderline ovarian tumor patients and survivors. Hormone Molecular Biology and Clinical Investigation 43:2, pages 179-186.
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Xuefeng Lu & Yanping Kuang. 2022. Ovarian Stimulation. Ovarian Stimulation 93 100 .
Marie-Madeleine Dolmans, Camille Hossay, Thu Yen Thi Nguyen & Catherine Poirot. (2021) Fertility Preservation: How to Preserve Ovarian Function in Children, Adolescents and Adults. Journal of Clinical Medicine 10:22, pages 5247.
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María Cerrillo, Gustavo Nardini Cecchino & María Cruz. (2021) What are the advantages of the DuoStim strategy?. Medicina Reproductiva y Embriología Clínica 8:3, pages 100105.
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Serkan Oral, Meriç Karacan, Yaşam K. Akpak, Alper Şişmanoğlu & Ceyda Sancaklı Usta. (2021) Live birth rate with double ovarian stimulation is superior to follicular phase ovarian stimulation per started cycle in poor ovarian responders. Journal of Obstetrics and Gynaecology Research 47:8, pages 2705-2712.
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Ana Cobo, Juan Antonio García-Velasco, José Remohí & Antonio Pellicer. (2021) Oocyte vitrification for fertility preservation for both medical and nonmedical reasons. Fertility and Sterility 115:5, pages 1091-1101.
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Kaja Michalczyk & Aneta Cymbaluk-Płoska. (2021) Fertility Preservation and Long-Term Monitoring of Gonadotoxicity in Girls, Adolescents and Young Adults Undergoing Cancer Treatment. Cancers 13:2, pages 202.
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HrishikeshD Pai, Rashmi Baid, NanditaP Palshetkar, Arnav Pai, RishmaD Pai & Rohan Palshetkar. (2021) Oocyte cryopreservation - current scenario and future perspectives: A narrative review. Journal of Human Reproductive Sciences 14:4, pages 340.
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Mehtap Polat, Sezcan Mumusoglu, Irem Yarali Ozbek, Gurkan Bozdag & Hakan Yarali. (2021) Double or dual stimulation in poor ovarian responders: where do we stand?. Therapeutic Advances in Reproductive Health 15, pages 263349412110241.
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Margherita Condorelli, Oranite Goldrat & Isabelle Demeestere. 2021. Survivorship Care for Cancer Patients. Survivorship Care for Cancer Patients 233 256 .
Laura C. Gemmell, Jason D. Wright & Paula C. Brady. (2020) Triple stimulation (TriStim) before bilateral oophorectomy in a young woman with ovarian cancer: a case report and review of the literature. Fertility Research and Practice 6:1.
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M. Lambertini, F.A. Peccatori, I. Demeestere, F. Amant, C. Wyns, J.-B. Stukenborg, S. Paluch-Shimon, M.J. Halaska, C. Uzan, J. Meissner, M. von Wolff, R.A. Anderson & K. Jordan. (2020) Fertility preservation and post-treatment pregnancies in post-pubertal cancer patients: ESMO Clinical Practice Guidelines†. Annals of Oncology 31:12, pages 1664-1678.
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Ami N. Shah, Marissa Luck, Kara Goldman & William Gradishar. (2020) Addressing Fertility: an Essential Aspect of Comprehensive Care for Young Patients with Breast Cancer. Current Breast Cancer Reports 12:4, pages 381-390.
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Demian Glujovsky, Romina Pesce, Mariana Miguens, Carlos E. Sueldo, Karinna Lattes & Agustín Ciapponi. (2020) How effective are the non-conventional ovarian stimulation protocols in ART? A systematic review and meta-analysis. Journal of Assisted Reproduction and Genetics 37:12, pages 2913-2928.
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Alberto Vaiarelli, Danilo Cimadomo, Erminia Alviggi, Anna Sansone, Elisabetta Trabucco, Ludovica Dusi, Laura Buffo, Nicoletta Barnocchi, Fabrizio Fiorini, Silvia Colamaria, Maddalena Giuliani, Cindy Argento, Laura Rienzi & Filippo Maria Ubaldi. (2020) The euploid blastocysts obtained after luteal phase stimulation show the same clinical, obstetric and perinatal outcomes as follicular phase stimulation-derived ones: a multicenter study. Human Reproduction 35:11, pages 2598-2608.
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Nathalie Sermondade, Michaël Grynberg, Marjorie Comtet, Constance Valdelievre, Christophe Sifer & Charlotte Sonigo. (2020) Double-in vitro maturation increases the number of vitrified oocytes available for fertility preservation when ovarian stimulation is unfeasible. Scientific Reports 10:1.
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Angela Baerwald & Roger Pierson. (2020) Ovarian follicular waves during the menstrual cycle: physiologic insights into novel approaches for ovarian stimulation. Fertility and Sterility 114:3, pages 443-457.
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Dongming Liu, Jie Yan & Jie Qiao. (2019) Effects of malignancies on fertility preservation outcomes and relevant cryobiological advances. Science China Life Sciences 63:2, pages 217-227.
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Sukhkamal B. Campbell & Terri L. Woodard. (2020) An update on fertility preservation strategies for women with cancer. Gynecologic Oncology 156:1, pages 3-5.
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Alberto Vaiarelli, Danilo Cimadomo, Alessandro Conforti, Mauro Schimberni, Maddalena Giuliani, Pietro D’Alessandro, Silvia Colamaria, Carlo Alviggi, Laura Rienzi & Filippo Maria Ubaldi. (2020) Luteal phase after conventional stimulation in the same ovarian cycle might improve the management of poor responder patients fulfilling the Bologna criteria: a case series. Fertility and Sterility 113:1, pages 121-130.
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Mathilde Bourdon, Pietro Santulli, Chloé Maignien, Khaled Pocate-Cheriet, Louis Marcellin, Yulian Chen & Charles Chapron. (2020) The Ovarian Response After Follicular Versus Luteal Phase Stimulation with a Double Stimulation Strategy. Reproductive Sciences 27:1, pages 204-210.
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Qiuju Chen & Yanping Kuang. 2020. Pick Up and Oocyte Management. Pick Up and Oocyte Management 179 194 .
Isabelle Demeestere. 2020. Fertility Challenges and Solutions in Women with Cancer. Fertility Challenges and Solutions in Women with Cancer 25 42 .
Rachel M. Whynott & Hakan E. Duran. 2020. Diminished Ovarian Reserve and Assisted Reproductive Technologies. Diminished Ovarian Reserve and Assisted Reproductive Technologies 329 338 .
Alberto Vaiarelli, Danilo Cimadomo, Cindy Argento, Nicolò Ubaldi, Elisabetta Trabucco, Panagiotis Drakopoulos, Roberta Venturella, Alessandro Conforti, Carlo Alviggi, Laura Rienzi & Filippo M. Ubaldi. (2019) Double stimulation in the same ovarian cycle (DuoStim) is an intriguing strategy to improve oocyte yield and the number of competent embryos in a short timeframe. Minerva Ginecologica 71:5.
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Kristine S. Corkum, Daniel S. Rhee, Q. Eileen Wafford, Isabelle Demeestere, Roshni Dasgupta, Reto Baertschiger, Marcus M. Malek, Jennifer H. Aldrink, Todd E. Heaton, Brent R. Weil, Mary Beth Madonna & Timothy B. Lautz. (2019) Fertility and hormone preservation and restoration for female children and adolescents receiving gonadotoxic cancer treatments: A systematic review. Journal of Pediatric Surgery 54:11, pages 2200-2209.
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Fatma Devran Bıldırcın, Ayşe Özdemir, Pervin Karlı & Mehmet Bilge Çetinkaya. (2019) Breast cancer and ovulation induction. Journal of Surgery and Medicine.
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Ross C Anderson, Claire L Newton, Richard A Anderson & Robert P Millar. (2018) Gonadotropins and Their Analogs: Current and Potential Clinical Applications. Endocrine Reviews 39:6, pages 911-937.
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H. Irene Su, Yuton Tony Lee & Ronald Barr. (2018) Oncofertility. The Cancer Journal 24:6, pages 328-335.
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Isabelle Streuli, Julie Benard, Justine Hugon-Rodin, Charles Chapron, Pietro Santulli & Nicola Pluchino. (2018) Shedding light on the fertility preservation debate in women with endometriosis: a swot analysis. European Journal of Obstetrics & Gynecology and Reproductive Biology 229, pages 172-178.
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Alberto Vaiarelli, Danilo Cimadomo, Elisabetta Trabucco, Roberta Vallefuoco, Laura Buffo, Ludovica Dusi, Fabrizio Fiorini, Nicoletta Barnocchi, Francesco Maria Bulletti, Laura Rienzi & Filippo Maria Ubaldi. (2018) Double Stimulation in the Same Ovarian Cycle (DuoStim) to Maximize the Number of Oocytes Retrieved From Poor Prognosis Patients: A Multicenter Experience and SWOT Analysis. Frontiers in Endocrinology 9.
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