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Cytotherapy Volume 11, 2009 - Issue 5
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Tumor Therapy

Clinical-grade manufacturing of autologous mature mRNA-electroporated dendritic cells and safety testing in acute myeloid leukemia patients in a phase I dose-escalation clinical trial

Ann Van Driessche Vaccine and Infectious Disease Institute (VIDI), Laboratory of Experimental Hematology, Faculty of Medicine, University of Antwerp, Belgium; Center for Cell Therapy and Regenerative Medicine, Antwerp University Hospital, Belgium
,
Ann L. R. Van de Velde Vaccine and Infectious Disease Institute (VIDI), Laboratory of Experimental Hematology, Faculty of Medicine, University of Antwerp, Belgium; Division of Hematology, Antwerp University Hospital, Belgium
,
Griet Nijs Vaccine and Infectious Disease Institute (VIDI), Laboratory of Experimental Hematology, Faculty of Medicine, University of Antwerp, Belgium; Center for Cell Therapy and Regenerative Medicine, Antwerp University Hospital, Belgium
,
Tessa Braeckman Vaccine and Infectious Disease Institute (VIDI), Laboratory of Experimental Hematology, Faculty of Medicine, University of Antwerp, Belgium
,
Barbara Stein Vaccine and Infectious Disease Institute (VIDI), Laboratory of Experimental Hematology, Faculty of Medicine, University of Antwerp, Belgium; Center for Cell Therapy and Regenerative Medicine, Antwerp University Hospital, Belgium
,
Jolanda M. De Vries Radboud Universiteit Nijmegen, Molecular Immunology, Centre for Molecular Life Sciences, Nijmegen, The Netherlands
,
Zwi N. Berneman Vaccine and Infectious Disease Institute (VIDI), Laboratory of Experimental Hematology, Faculty of Medicine, University of Antwerp, Belgium; Center for Cell Therapy and Regenerative Medicine, Antwerp University Hospital, Belgium; Division of Hematology, Antwerp University Hospital, Belgium
&
Viggo F. I. Van Tendeloo Vaccine and Infectious Disease Institute (VIDI), Laboratory of Experimental Hematology, Faculty of Medicine, University of Antwerp, Belgium; Center for Cell Therapy and Regenerative Medicine, Antwerp University Hospital, BelgiumCorrespondence[email protected]
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Pages 653-668 | Published online: 16 Sep 2009

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Aranit Harizaj, Stefaan C. De Smedt, Ine Lentacker & Kevin Braeckmans. (2021) Physical transfection technologies for macrophages and dendritic cells in immunotherapy. Expert Opinion on Drug Delivery 18:2, pages 229-247.
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Phillip D. Fromm, Michael S. Papadimitrious, Jennifer L. Hsu, Nicolas Van Kooten Losio, Nirupama D. Verma, Tsun Ho Lo, Pablo A. Silveira, Christian E. Bryant, Cameron J. Turtle, Rebecca L. Prue, Peter Vukovic, David J. Munster, Tomoko Nagasaki, Ross T. Barnard, Stephen M. Mahler, Sébastien A. Anguille, Zwi Berneman, Lisa G. Horvath, Kenneth F. Bradstock, Douglas E. Joshua, Georgina J. Clark & Derek N. J. Hart. (2016) CMRF-56+ blood dendritic cells loaded with mRNA induce effective antigen-specific cytotoxic T-lymphocyte responses. OncoImmunology 5:6.
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Maureen L. Drakes & Patrick J. Stiff. (2016) Understanding dendritic cell immunotherapy in ovarian cancer. Expert Review of Anticancer Therapy 16:6, pages 643-652.
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Colin de Haar, Maud Plantinga, Nina JG Blokland, Niek P van Til, Thijs WH Flinsenberg, Viggo F Van Tendeloo, Evelien L Smits, Louis Boon, Lotte Spel, Marianne Boes, Jaap Jan Boelens & Stefan Nierkens. (2015) Generation of a cord blood-derived Wilms Tumor 1 dendritic cell vaccine for AML patients treated with allogeneic cord blood transplantation. OncoImmunology 4:11.
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Drew Weissman. (2015) mRNA transcript therapy. Expert Review of Vaccines 14:2, pages 265-281.
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Patrick J Stiff, Cheryl Czerlanis & Maureen L Drakes. (2013) Dendritic cell immunotherapy in ovarian cancer. Expert Review of Anticancer Therapy 13:1, pages 43-53.
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Lorenzo Galluzzi, Laura Senovilla, Erika Vacchelli, Alexander Eggermont, Wolf Hervé Fridman, Jérôme Galon, Catherine Sautès-Fridman, Eric Tartour, Laurence Zitvogel & Guido Kroemer. (2012) Trial watch. OncoImmunology 1:7, pages 1111-1134.
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Sébastien Anguille, Yannick Willemen, Eva Lion, Evelien L. Smits & Zwi N. Berneman. (2012) Dendritic cell vaccination in acute myeloid leukemia. Cytotherapy 14:6, pages 647-656.
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Gheath Alatrash & Jeffrey J Molldrem. (2011) Vaccines as consolidation therapy for myeloid leukemia. Expert Review of Hematology 4:1, pages 37-50.
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Michael R Shurin, Melissa Gregory, John C Morris & Anatoli M Malyguine. (2010) Genetically modified dendritic cells in cancer immunotherapy: a better tomorrow?. Expert Opinion on Biological Therapy 10:11, pages 1539-1553.
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