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Hypomethylating agents (HMA) treatment for myelodysplastic syndromes: alternatives in the frontline and relapse settings

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Pages 1213-1224 | Received 26 Apr 2017, Accepted 27 Jun 2017, Published online: 01 Aug 2017

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Eytan M. Stein, Gaetano Bonifacio, Dominick Latrémouille-Viau, Sherry Shi, Annie Guérin, Eric Q. Wu, Islam Sadek & Xiting Cao. (2021) Healthcare resource utilization and costs in patients with myelodysplastic syndromes treated with hypomethylating agents: a SEER-Medicare analysis. Journal of Medical Economics 24:1, pages 234-243.
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Amer M Zeidan, Kiyoshi Ando, Odile Rauzy, Mehmet Turgut, Ming-Chung Wang, Roberto Cairoli, Hsin-An Hou, Yok-Lam Kwong, Montserrat Arnan, Stef Meers, Vinod Pullarkat, Valeria Santini, Kamel Malek, Flavia Kiertsman, Julie Niolat, Pedro Marques Ramos, Hans D Menssen, Pierre Fenaux, Yasushi Miyazaki & Uwe Platzbecker. (2023) Sabatolimab plus hypomethylating agents in previously untreated patients with higher-risk myelodysplastic syndromes (STIMULUS-MDS1): a randomised, double-blind, placebo-controlled, phase 2 trial. The Lancet Haematology.
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Andrew M. Brunner, Jordi Esteve, Kimmo Porkka, Steve Knapper, Elie Traer, Sebastian Scholl, Guillermo Garcia‐Manero, Norbert Vey, Martin Wermke, Jeroen J. W. M. Janssen, Rupa Narayan, Shaun Fleming, Sun Loo, Natalia Tovar, Mika Kontro, Oliver G. Ottmann, Purushotham Naidu, Haiying Sun, May Han, Roisin White, Na Zhang, Anisa Mohammed, Catherine A. Sabatos‐Peyton, David P. Steensma, Mikael L. Rinne, Uma M. Borate & Andrew H. Wei. (2023) Phase Ib study of sabatolimab ( MBG453 ), a novel immunotherapy targeting TIM‐3 antibody, in combination with decitabine or azacitidine in high‐ or very high‐risk myelodysplastic syndromes . American Journal of Hematology.
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José Guilherme de Almeida, Emma Gudgin, Martin Besser, William G. Dunn, Jonathan Cooper, Torsten Haferlach, George S. Vassiliou & Moritz Gerstung. (2023) Computational analysis of peripheral blood smears detects disease-associated cytomorphologies. Nature Communications 14:1.
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Abhay Singh & Hetty E. Carraway. (2023) Overview of the Management of Higher-Risk Myelodysplastic Syndromes. The Cancer Journal 29:3, pages 160-167.
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Amer M Zeidan, Aristoteles Giagounidis, Mikkael A Sekeres, Zhijian Xiao, Guillermo F Sanz, Marlies Van Hoef, Fei Ma, Sabine Hertle & Valeria Santini. (2023) STIMULUS-MDS2 design and rationale: a phase III trial with the anti-TIM-3 sabatolimab (MBG453) + azacitidine in higher risk MDS and CMML-2. Future Oncology 19:9, pages 631-642.
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Pauline P. Frank, Mabel X. E. Lu & Emma C. Sasse. (2022) Educational and Emotional Needs of Patients with Myelodysplastic Syndromes: An AI Analysis of Multi-Country Social Media. Advances in Therapy 40:1, pages 159-173.
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Uma M. Borate. 2017. Holland‐Frei Cancer Medicine. Holland‐Frei Cancer Medicine 1 20 .
Anson Snow & Joshua F. Zeidner. (2022) The development of pevonedistat in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML): hope or hype?. Therapeutic Advances in Hematology 13, pages 204062072211128.
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Shukaib Arslan, Samer Khaled & Ryotaro Nakamura. 2021. Biology and Treatment of Leukemia and Bone Marrow Neoplasms. Biology and Treatment of Leukemia and Bone Marrow Neoplasms 115 132 .
Jan Philipp Bewersdorf, Hetty Carraway & Thomas Prebet. (2020) Emerging treatment options for patients with high-risk myelodysplastic syndrome. Therapeutic Advances in Hematology 11, pages 204062072095500.
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Roberto Castelli, Riccardo Schiavon & Giorgio Lambertenghi Deliliers. (2018) The impact of anaemia, transfusion dependency, comorbidities and polypharmacy in elderly patients with low-risk myelodysplastic syndromes. Medical Oncology 35:3.
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