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Review

Pharmacotherapy for the treatment of vaginal atrophy

ORCID Icon, , &
Pages 821-835 | Received 18 Sep 2018, Accepted 22 Jan 2019, Published online: 21 Mar 2019

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Gilbert G.G. Donders & Francesca H.W.V. Donders. (2023) New developments in the management of vulvovaginal atrophy: a comprehensive overview. Expert Opinion on Pharmacotherapy 24:5, pages 599-616.
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Stefano Salvatore, Vittoria Benini, Alessandro Ferdinando Ruffolo, Rebecca S. Degliuomini, Anna Redaelli, Arianna Casiraghi & Massimo Candiani. (2023) Current challenges in the pharmacological management of genitourinary syndrome of menopause. Expert Opinion on Pharmacotherapy 24:1, pages 23-28.
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F. R. Pérez-López & S. R. Varikasuvu. (2022) Vulvovaginal atrophy management with a laser: the placebo effect or the conditioning Pavlov reflex. Climacteric 25:4, pages 323-326.
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R. E. Nappi, M. Kotek, A. Brešt’anský, N. Giordan & E. Tramentozzi. (2020) Effectiveness of hyaluronate-based pessaries in the treatment of vulvovaginal atrophy in postmenopausal women. Climacteric 23:5, pages 519-524.
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Articles from other publishers (29)

Mohammed M. Hassanein, Hasniza Zaman Huri, Abduelmula R. Abduelkarem & Kauser Baig. (2023) Therapeutic Effects of Vitamin D on Vaginal, Sexual, and Urological Functions in Postmenopausal Women. Nutrients 15:17, pages 3804.
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Nada Saleh Albalawi, Maram Ati Almohammadi & Ahmad Raja Albalawi. (2023) Comparison of the Efficacy of Vaginal Hyaluronic Acid to Estrogen for the Treatment of Vaginal Atrophy in Postmenopausal Women: A Systematic Review. Cureus.
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Elizabeth Schmidt. (2023) A practical guide to managing genitourinary syndrome of menopause in primary care. JAAPA Published Ahead of Print.
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Łukasz Nowakowski, Krzysztof Gałczyński, Michał Dybowski, Rafał Typek, Andrzej Dawidowicz, Paweł Miotła, Piotr Olcha & Tomasz Rechberger. (2023) Effects of topical dehydroepiandrosterone therapy in women after pelvic organ prolapse surgery. Menopause 30:6, pages 629-634.
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Fatemeh Zahra Karimi, Nahid Nazari, Hassan Rakhshandeh & Seyed Reza Mazloum. (2023) The effect of nettle vaginal cream on subjective symptoms of vaginal atrophy in postmenopausal women. European Journal of Obstetrics & Gynecology and Reproductive Biology 285, pages 41-45.
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Ulysse Gaspard, Mélanie Taziaux, Maud Jost, Herjan J.T. Coelingh Bennink, Wulf H. Utian, Rogerio A. Lobo & Jean-Michel Foidart. (2023) A multicenter, randomized, placebo-controlled study to select the minimum effective dose of estetrol in postmenopausal participants (E4Relief): part 2—vaginal cytology, genitourinary syndrome of menopause, and health-related quality of life. Menopause 30:5, pages 480-489.
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Mohammed M. Hassanein, Hasniza Zaman Huri, Kauser Baig & Abduelmula R. Abduelkarem. (2023) Determinants and Effects of Vitamin D Supplementation in Postmenopausal Women: A Systematic Review. Nutrients 15:3, pages 685.
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Rossella E. NAPPI, Miroslav KOTEK, Alexander BREŠTÁNSKÝ, Nicola GIORDAN, Irene BERIOTTO & Elisa TRAMENTOZZI. (2022) Treatment of vulvo-vaginal atrophy with hyaluronate-based gel: a randomized controlled study. Minerva Obstetrics and Gynecology 74:6.
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E. N. Andreeva & E. V. Sheremetyeva. (2022) The role of estriol in the treatment of atrophy of the mucous membrane of the lower genitourinary tract in postmenopausal women. Problems of Endocrinology 68:6, pages 157-163.
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Leslie R. Schover. 2016. Holland‐Frei Cancer Medicine. Holland‐Frei Cancer Medicine 1 6 .
Doaa M. Saleh & Rania Abdelghani. (2022) Clinical evaluation of autologous platelet rich plasma injection in postmenopausal vulvovaginal atrophy: A pilot study. Journal of Cosmetic Dermatology 21:10, pages 4269-4275.
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Naziye GÜRKAN, Nur DOKUZEYLÜL GÜNGÖR, Asena AYAR MADENLİ & Şebnem ALANYA TOSUN. (2022) Evaluation of the impact of platelet-rich plasma in women with reduced ovarian reserve. Journal of Health Sciences and Medicine 5:5, pages 1334-1338.
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Rossella E. Nappi, Silvia Martella, Francesca Albani, Chiara Cassani, Ellis Martini & Fabio Landoni. (2022) Hyaluronic Acid: A Valid Therapeutic Option for Early Management of Genitourinary Syndrome of Menopause in Cancer Survivors?. Healthcare 10:8, pages 1528.
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Zhaojun Mei & Dandan Li. (2022) The role of probiotics in vaginal health. Frontiers in Cellular and Infection Microbiology 12.
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Miles S. Harris, B. Ashby Goodrum & Chance N. Krempasky. (2022) An introduction to gender-affirming hormone therapy for transgender and gender-nonbinary patients. The Nurse Practitioner 47:3, pages 18-28.
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. (2022) Hemorragia genital secundaria a la terapia de reemplazo hormonal en una paciente geriátrica: reporte de caso de queja médica. Revista CONAMED 27:2, pages 84-88.
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. (2021) Treatment of Urogenital Symptoms in Individuals With a History of Estrogen-dependent Breast Cancer. Obstetrics & Gynecology 138:6, pages 950-960.
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Rossella E. Nappi, Laura Cucinella, Ellis Martini & Chiara Cassani. (2021) The role of hormone therapy in urogenital health after menopause. Best Practice & Research Clinical Endocrinology & Metabolism 35:6, pages 101595.
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Matthias Kiesel, Achim WöckelChristoph ZellerHarald Meden. (2021) Treatment of Vulvovaginal Atrophy with Fractional CO 2 Laser: Evaluating Real-World Data . Photobiomodulation, Photomedicine, and Laser Surgery 39:11, pages 716-724.
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Yulia E. Dobrokhotova, Polina A. Shadrova & Vladimir I. Komagorov. (2021) Vaginal microbiota during the menopausal transition: the role of lactobacilli. Gynecology 23:3, pages 214-221.
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Nancy A. Phillips & Gloria A. Bachmann. (2021) The genitourinary syndrome of menopause. Menopause 28:5, pages 579-588.
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O.A. Burka, N.F. Lygyrda, V.V. Kutsovol & A.V. Svintsitska. (2021) The cytological component of cervical cancer screening: causes of false negative and false positive results, and ways to avoid them. REPRODUCTIVE ENDOCRINOLOGY:57, pages 61-67.
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Rupali Sani Kumar & Neena Goyal. (2021) Estrogens as regulator of hematopoietic stem cell, immune cells and bone biology. Life Sciences 269, pages 119091.
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Iris Holzer. (2021) Vaginale AtrophieVaginal Atrophy. Journal für Gynäkologische Endokrinologie/Österreich 31:1, pages 41-42.
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Wenhui Qi, Huiyang Li, Chen Wang, Huanrong Li, Aiping Fan, Cha Han & Fengxia Xue. (2021) The effect of pathophysiological changes in the vaginal milieu on the signs and symptoms of genitourinary syndrome of menopause (GSM). Menopause 28:1, pages 102-108.
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L. Photiou, M.J. Lin, D.P. Dubin, V. Lenskaya & H. Khorasani. (2019) Review of non‐invasive vulvovaginal rejuvenation. Journal of the European Academy of Dermatology and Venereology 34:4, pages 716-726.
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Siya Lodhia, Ala'a Sharaf & Charlotte Foley. (2020) Management of recurrent urinary tract infections in adults. Surgery (Oxford) 38:4, pages 197-203.
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V.E. Balan, K.V. Krasnopolskaya, M.R. Orazov, L.R. Toktar & E.V. Tikhomirova. (2020) Collagenotherapy for patients with genitourinary menopausal syndrome is a new opportunity in the doctor’s arsenal. Rossiiskii vestnik akushera-ginekologa 20:4, pages 65.
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Rossella E. Nappi, Ellis Martini, Laura Cucinella, Silvia Martella, Lara Tiranini, Alessandra Inzoli, Emanuela Brambilla, David Bosoni, Chiara Cassani & Barbara Gardella. (2019) Addressing Vulvovaginal Atrophy (VVA)/Genitourinary Syndrome of Menopause (GSM) for Healthy Aging in Women. Frontiers in Endocrinology 10.
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