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Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders Volume 1, 2000 - Issue sup1
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Research Article

Pathophysiological significance of fasciculations in the early diagnosis of ALS

Mamede de Carvalho Neurology Department and EMG laboratory, Centro de Estudos Egas Moniz, Hospital of Santa Maria, Lisbon, Portugal
Pages S43-S46 | Published online: 10 Jul 2009

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Ellen M. Maathuis, Judith Drenthen, Pieter A. van Doorn, Gerhard H. Visser & Joleen H. Blok. (2012) Multiplet discharges after electrical stimulation: New evidence for distal excitability changes in motor neuron disease. Amyotrophic Lateral Sclerosis 13:6, pages 514-520.
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Articles from other publishers (31)

Sonam Dolma & Abhijeet Joshi. (2023) The Node of Ranvier as an Interface for Axo-Glial Interactions: Perturbation of Axo-Glial Interactions in Various Neurological Disorders. Journal of Neuroimmune Pharmacology.
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Mark Crook‐Rumsey, Abdi Malik Musa, Raquel Iniesta, Emmanuel Drakakis, Martyn G. Boutelle, Christopher E. Shaw & James Bashford. (2022) A shortened surface electromyography recording is sufficient to facilitate home fasciculation assessment. Muscle & Nerve 66:5, pages 625-630.
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Andreas PosaMalte Kornhuber. (2021) EMG-Phänomene peripherer motorisch axonaler Übererregbarkeit. Klinische Neurophysiologie 53:02, pages 99-106.
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Márcio Luís Duarte, Wagner Iared, Acary Souza Bulle Oliveira, Lucas Ribeiro dos Santos & Maria Stella Peccin. (2020) Ultrasound versus electromyography for the detection of fasciculation in amyotrophic lateral sclerosis: systematic review and meta-analysis. Radiologia Brasileira 53:2, pages 116-121.
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James A Bashford, Aidan Wickham, Raquel Iniesta, Emmanuel M Drakakis, Martyn G Boutelle, Kerry R Mills & Chris E Shaw. (2020) The rise and fall of fasciculations in amyotrophic lateral sclerosis. Brain Communications 2:1.
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J. Bashford, A. Wickham, R. Iniesta, E. Drakakis, M. Boutelle, K. Mills & CE. Shaw. (2020) Preprocessing surface EMG data removes voluntary muscle activity and enhances SPiQE fasciculation analysis. Clinical Neurophysiology 131:1, pages 265-273.
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Ali Amin Lari, Amer A. Ghavanini & Hamid Reza Bokaee. (2019) A review of electrophysiological studies of lower motor neuron involvement in amyotrophic lateral sclerosis. Neurological Sciences 40:6, pages 1125-1136.
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Devon I. Rubin. 2019. Clinical Neurophysiology: Basis and Technical Aspects. Clinical Neurophysiology: Basis and Technical Aspects 257 279 .
Yosuke Miyaji, Yuki Hatanaka, Mana Higashihara, Takamichi Kanbayashi, Fumiaki Tanaka & Masahiro Sonoo. (2018) Fasciculation potentials and decremental responses in amyotrophic lateral sclerosis. Clinical Neurophysiology 129:2, pages 345-348.
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Kota Bokuda, Toshio Shimizu, Hideki Kimura, Toshihiro Yamazaki, Tsutomu Kamiyama, Kazuhiko Watabe, Akihiro Kawata, Masaharu Hayashi & Eiji Isozaki. (2016) Quantitative analysis of the features of fasciculation potentials and their relation with muscle strength in amyotrophic lateral sclerosis. Neurological Sciences 37:12, pages 1939-1945.
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Hua Pan, Fan Jian, Jinxi Lin, Na Chen, Zaiqiang Zhang, Yongjun Wang, Liying Cui & Jun Kimura. (2016) Needle electromyography of the frontalis muscle in patients with amyotrophic lateral sclerosis. Muscle & Nerve 54:6, pages 1093-1096.
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Jean-Pascal Lefaucheur & Mamede de Carvalho. (2016) New insights into the clinical neurophysiological assessment of ALS. Neurophysiologie Clinique/Clinical Neurophysiology 46:3, pages 157-163.
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Rubika Balendra & Rickie Patani. (2016) Quo vadis motor neuron disease?. World Journal of Methodology 6:1, pages 56.
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Alida Spalloni & Patrizia Longone. (2016) Cognitive impairment in amyotrophic lateral sclerosis, clues from the SOD1 mouse. Neuroscience & Biobehavioral Reviews 60, pages 12-25.
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Anna E. King, Adele Woodhouse, Matthew T.K. Kirkcaldie & James C. Vickers. (2016) Excitotoxicity in ALS: Overstimulation, or overreaction?. Experimental Neurology 275, pages 162-171.
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Toshio Shimizu, Yumi Fujimaki, Setsu Nakatani-Enomoto, Shiro Matsubara, Kazuhiko Watabe, Paolo Maria Rossini & Yoshikazu Ugawa. (2014) Complex fasciculation potentials and survival in amyotrophic lateral sclerosis. Clinical Neurophysiology 125:5, pages 1059-1064.
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Faezeh Jahanmiri-Nezhad, Xiaoyan Li, Paul E. Barkhaus, William Z. Rymer & Ping Zhou. (2014) A Clinically Applicable Approach for Detecting Spontaneous Action Potential Spikes in Amyotrophic Lateral Sclerosis With a Linear Electrode Array. Journal of Clinical Neurophysiology 31:1, pages 35-40.
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Steve Vucic, Ulf Ziemann, Andrew Eisen, Mark Hallett & Matthew C Kiernan. (2013) Transcranial magnetic stimulation and amyotrophic lateral sclerosis: pathophysiological insights. Journal of Neurology, Neurosurgery & Psychiatry 84:10, pages 1161-1170.
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Yoshiko Shibuta, Yoshimitsu Shimatani, Hiroyuki Nodera, Yuishin Izumi & Ryuji Kaji. (2013) Increased variability of axonal excitability in amyotrophic lateral sclerosis. Clinical Neurophysiology 124:10, pages 2046-2053.
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Mariana C. Rocha, Paula A. Pousinha, Alexandra M. Correia, Ana M. Sebastião & Joaquim A. Ribeiro. (2013) Early Changes of Neuromuscular Transmission in the SOD1(G93A) Mice Model of ALS Start Long before Motor Symptoms Onset. PLoS ONE 8:9, pages e73846.
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M. de Carvalho & M. Swash. (2013) Fasciculation potentials and earliest changes in motor unit physiology in ALS. Journal of Neurology, Neurosurgery & Psychiatry 84:9, pages 963-968.
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Nanette C. Joyce & Gregory T. Carter. (2013) Electrodiagnosis in Persons With Amyotrophic Lateral Sclerosis. PM&R 5, pages S89-S95.
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Mana Higashihara, Masahiro Sonoo, Ichiro Imafuku, Toshio Fukutake, Keiko Kamakura, Kiyoharu Inoue, Yuki Hatanaka, Teruo Shimizu, Shoji Tsuji & Yoshikazu Ugawa. (2012) Fasciculation potentials in amyotrophic lateral sclerosis and the diagnostic yield of the Awaji algorithm. Muscle & Nerve 45:2, pages 175-182.
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Ping Zhou, Xiaoyan Li, Faezeh Jahanmiri-Nezhad, William Rymer & Paul E Barkhaus. (2012) Duration of observation required in detecting fasciculation potentials in amyotrophic lateral sclerosis using high-density surface EMG. Journal of NeuroEngineering and Rehabilitation 9:1, pages 78.
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Christian Krarup. (2011) Lower motor neuron involvement examined by quantitative electromyography in amyotrophic lateral sclerosis. Clinical Neurophysiology 122:2, pages 414-422.
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Kerry R. Mills. (2010) Characteristics of fasciculations in amyotrophic lateral sclerosis and the benign fasciculation syndrome. Brain 133:11, pages 3458-3469.
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Masahiro Sonoo, Satoshi Kuwabara, Toshio Shimizu, Tetsuo Komori, Fumiko Hirashima, Akira Inaba, Yuki Hatanaka, Sonoko Misawa & Yumiko Kugio. (2009) Utility of trapezius EMG for diagnosis of amyotrophic lateral sclerosis. Muscle & Nerve 39:1, pages 63-70.
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Andrew Eisen & Charles Krieger. 2004. Clinical Neurophysiology of Motor Neuron Diseases. Clinical Neurophysiology of Motor Neuron Diseases 469 485 .
Jasper R. Daube & Eric J. Sorenson. 2004. Clinical Neurophysiology of Motor Neuron Diseases. Clinical Neurophysiology of Motor Neuron Diseases 221 240 .
David A Chad. (2002) Electrodiagnostic approach to the patient with suspected motor neuron disease. Neurologic Clinics 20:2, pages 527-555.
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Andrew Eisen & Michael Swash. (2001) Clinical neurophysiology of ALS. Clinical Neurophysiology 112:12, pages 2190-2201.
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