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Expert Opinion on Biological Therapy Volume 17, 2017 - Issue 10
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Review

Challenges and opportunities in the manufacture and expansion of cells for therapy

Joachim H. MaartensInstitute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia;Cooperative Research Centre for Cell Therapy Manufacturing, Adelaide, AustraliaView further author information
,
Elena De-Juan-PardoInstitute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia;Cooperative Research Centre for Cell Therapy Manufacturing, Adelaide, AustraliaView further author information
,
Felix M. WunnerInstitute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia;Cooperative Research Centre for Cell Therapy Manufacturing, Adelaide, AustraliaView further author information
,
Antonio SimulaCooperative Research Centre for Cell Therapy Manufacturing, Adelaide, AustraliaView further author information
,
Nicolas H. VoelckerCooperative Research Centre for Cell Therapy Manufacturing, Adelaide, Australia;ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Future Industries Institute, University of South Australia, Adelaide, AustraliaView further author information
,
Simon C. BarryCooperative Research Centre for Cell Therapy Manufacturing, Adelaide, Australia;Molecular Immunology, Department of Gastroenterology, Women’s and Children’s Hospital, Adelaide, Australia;Robinson Research Institute, University of Adelaide, Adelaide, AustraliaView further author information
&
Dietmar W. HutmacherInstitute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia;Cooperative Research Centre for Cell Therapy Manufacturing, Adelaide, Australia;ARC Centre in Additive Biomanufacturing, Queensland University of Technology, Brisbane, AustraliaCorrespondence[email protected]
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Pages 1221-1233 | Received 16 Mar 2017, Accepted 24 Jul 2017, Published online: 18 Aug 2017

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Wenbin Lu, JingJing Ji, Genshan Ma, Qiming Dai, Lijuan Chen, Pengfei Zuo & Yuanjin Zhao. (2018) Inverse opal substrate-loaded mesenchymal stem cells contribute to decreased myocardial remodeling after transplantation into acute myocardial infarction mice. International Journal of Nanomedicine 13, pages 7033-7046.
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Articles from other publishers (10)

Joachim Maartens & Dietmar W. Hutmacher. 2022. Novel Innovation Design for the Future of Health. Novel Innovation Design for the Future of Health 391 408 .
Xia Luo, Yinjie Niu, Xiaozhe Fu, Qiang Lin, Hongru Liang, Lihui Liu & Ningqiu Li. (2021) Large-Scale Microcarrier Culture of Chinese Perch Brain Cell for Viral Vaccine Production in a Stirred Bioreactor. Vaccines 9:9, pages 1003.
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Timothée Baudequin, Robin Nyland & Hua Ye. (2021) Objectives, benefits and challenges of bioreactor systems for the clinical-scale expansion of T lymphocyte cells. Biotechnology Advances 49, pages 107735.
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Hiroka Sugai, Shunsuke Tomita, Sayaka Ishihara, Kyoko Yoshioka & Ryoji Kurita. (2020) Microfluidic Sensing System with a Multichannel Surface Plasmon Resonance Chip: Damage-Free Characterization of Cells by Pattern Recognition. Analytical Chemistry 92:22, pages 14939-14946.
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Sreedevi Raman, Gayathri Srinivasan, Nicholas Brookhouser, Toan Nguyen, Tanner Henson, Daylin Morgan, Joshua Cutts & David A. Brafman. (2020) A Defined and Scalable Peptide-Based Platform for the Generation of Human Pluripotent Stem Cell-Derived Astrocytes. ACS Biomaterials Science & Engineering 6:6, pages 3477-3490.
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Jianjun Yang, Patrick Guertin, Guodong Jia, Zhongliang Lv, Hongyan Yang & Dianwen Ju. (2019) Large-scale microcarrier culture of HEK293T cells and Vero cells in single-use bioreactors. AMB Express 9:1.
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C.L. Nemeth, A.S. Fine & A. Fatemi. (2019) Translational challenges in advancing regenerative therapy for treating neurological disorders using nanotechnology. Advanced Drug Delivery Reviews 148, pages 60-67.
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Donald G. Phinney & Jacques Galipeau. (2019) Manufacturing mesenchymal stromal cells for clinical applications: A survey of Good Manufacturing Practices at U.S. academic centers. Cytotherapy 21:7, pages 782-792.
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Chijioke H Mosanya & John D Isaacs. (2019) Tolerising cellular therapies: what is their promise for autoimmune disease?. Annals of the Rheumatic Diseases 78:3, pages 297-310.
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George M. Vlăsceanu, Roxana-Maria Amărandi, Mariana Ioniță, Teddy Tite, Horia Iovu, Luisa Pilan & Jorge S. Burns. (2018) Versatile graphene biosensors for enhancing human cell therapy. Biosensors and Bioelectronics 117, pages 283-302.
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