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Expert Opinion on Therapeutic Targets Volume 24, 2020 - Issue 8
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Review

Novel regulators of PrPC expression as potential therapeutic targets in prion diseases

Arianna Colini Baldeschia Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore Di Studi Avanzati (SISSA), Trieste, ItalyView further author information
,
Silvia Vannib Osteoncology and Rare Tumors Center, Istituto Scientifico Romagnolo per Lo Studio E La Cura Dei Tumori (IRST) IRCCS, Meldola, ItalyView further author information
,
Marco Zattonia Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore Di Studi Avanzati (SISSA), Trieste, ItalyView further author information
&
Giuseppe Legnamea Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore Di Studi Avanzati (SISSA), Trieste, ItalyCorrespondence[email protected]
View further author information
Pages 759-776 | Received 24 Feb 2020, Accepted 10 Jun 2020, Published online: 07 Jul 2020

Citations (9)

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Read on this site (2)

Lea Nikolić, Chiara Ferracin & Giuseppe Legname. (2022) Recent advances in cellular models for discovering prion disease therapeutics. Expert Opinion on Drug Discovery 17:9, pages 985-996.
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Marco Zattoni & Giuseppe Legname. (2021) Tackling prion diseases: a review of the patent landscape. Expert Opinion on Therapeutic Patents 31:12, pages 1097-1115.
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Articles from other publishers (7)

Elisa Uliassi, Lea Nikolic, Maria Laura Bolognesi & Giuseppe Legname. (2022) Therapeutic strategies for identifying small molecules against prion diseases. Cell and Tissue Research 392:1, pages 337-347.
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Mateusz de Mezer, Jan Rogaliński, Stanisław Przewoźny, Michał Chojnicki, Leszek Niepolski, Magdalena Sobieska & Agnieszka Przystańska. (2023) SERPINA3: Stimulator or Inhibitor of Pathological Changes. Biomedicines 11:1, pages 156.
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Matteo Staderini, Silvia Vanni, Arianna Colini Baldeschi, Gabriele Giachin, Marco Zattoni, Luigi Celauro, Chiara Ferracin, Edoardo Bistaffa, Fabio Moda, Daniel I. Pérez, Ana Martínez, M. Antonia Martín, Olmo Martín-Cámara, Ángel Cores, Giulia Bianchini, Robert Kammerer, J. Carlos Menéndez, Giuseppe Legname & Maria Laura Bolognesi. (2023) Bifunctional carbazole derivatives for simultaneous therapy and fluorescence imaging in prion disease murine cell models. European Journal of Medicinal Chemistry 245, pages 114923.
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Luigi Celauro, Marco Zattoni & Giuseppe Legname. 2023. Receptor Endocytosis And Signalling In Health And Disease - Part B. Receptor Endocytosis And Signalling In Health And Disease - Part B 15 41 .
Arianna Colini Baldeschi, Marco Zattoni, Silvia Vanni, Lea Nikolic, Chiara Ferracin, Giuseppina La Sala, Maria Summa, Rosalia Bertorelli, Sine Mandrup Bertozzi, Gabriele Giachin, Paolo Carloni, Maria Laura Bolognesi, Marco De Vivo & Giuseppe Legname. (2022) Innovative Non-PrP-Targeted Drug Strategy Designed to Enhance Prion Clearance. Journal of Medicinal Chemistry 65:13, pages 8998-9010.
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Jennifer Abrams, Taylor Arhar, Sue Ann Mok, Isabelle R. Taylor, Martin Kampmann & Jason E. Gestwicki. (2021) Functional genomics screen identifies proteostasis targets that modulate prion protein (PrP) stability. Cell Stress and Chaperones 26:2, pages 443-452.
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Andrea Astolfi, Giovanni Spagnolli, Emiliano Biasini & Maria Letizia Barreca. (2020) The Compelling Demand for an Effective PrP C -Directed Therapy against Prion Diseases . ACS Medicinal Chemistry Letters 11:11, pages 2063-2067.
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