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Research Article

Potent inhibition of fatty acid synthase by parasitic loranthus [Taxillus chinensis (DC.) Danser] and its constituent avicularin

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Pages 87-93 | Received 05 Aug 2005, Accepted 09 Oct 2005, Published online: 04 Oct 2008

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Wen-Hua Zhao, ChunChun Gao, Ying-Xia Zhang & Wei-Xi Tian. (2007) Evaluation of the inhibitory activities of aceraceous plants on fatty acid synthase. Journal of Enzyme Inhibition and Medicinal Chemistry 22:4, pages 501-510.
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Ting Qiu, Jia-Xue Shi, Chao Cheng, Hong Jiang, Hai-Nan Ruan, Jun Li & Chan-Min Liu. (2023) Hepatoprotective effect of avicularin on lead-induced steatosis, oxidative stress, and inflammation in mice associated with the MAPK/HSP60/NLRP3 and SREBP1c pathway. Toxicology Research 12:3, pages 417-424.
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Mi Qin, Qianqian Huang, Xin Yang, Lu Yu, Yong Tang, Chunxiang Zhang, Dalian Qin, Wenjun Zou, Junzhu Deng, Jian Liu, Haiyang Hu, Long Wang, Anguo Wu & Jianming Wu. (2022) Taxillus chinensis (DC.) Danser: a comprehensive review on botany, traditional uses, phytochemistry, pharmacology, and toxicology. Chinese Medicine 17:1.
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Kanika Patel & Dinesh Kumar Patel. (2022) Health Benefits of Avicularin in the Medicine Against Cancerous Disorders and other Complications: Biological Importance, Therapeutic Benefit and Analytical Aspects. Current Cancer Therapy Reviews 18:1, pages 41-50.
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Li Li, Jianbei Teng, Yilin Zhu, Fengfeng Xie, Jing Hou, Yuan Ling & Hua Zhu. (2021) Metabolomics Study of Flavonoids of Taxilluschinensis on Different Hosts Using UPLC-ESI-MS/MS. Molecules 26:24, pages 7681.
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Hezhong Jiang, Tian Gan, Jiasui Zhang, Qingyun Ma, Yan Liang & Youxing Zhao. (2019) The Structures and Bioactivities of Fatty Acid Synthase Inhibitors. Current Medicinal Chemistry 26:39, pages 7081-7101.
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Ying Li, Jian-guo Zhou, Xin-lian Chen, Ying-xian Cui, Zhi-chao Xu, Yong-hua Li, Jing-yuan Song, Bao-zhong Duan & Hui Yao. (2017) Gene losses and partial deletion of small single-copy regions of the chloroplast genomes of two hemiparasitic Taxillus species. Scientific Reports 7:1.
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Hildebert Wagner, Stefanie Püls, Talee Barghouti, Anton Staudinger & Dieter Melchart. 2017. Chromatographic Fingerprint Analysis of Herbal Medicines Volume V. Chromatographic Fingerprint Analysis of Herbal Medicines Volume V 63 70 .
Mingxia Li, Shuangjia Xue, Si Tan, Xiaoxiao Qin, Ming Gu, Dongshan Wang, Yu Zhang, Lu Guo, Feisi Huang, Yunchong Yao, Zhiqin Zhou, Shengjie Fan & Cheng Huang. (2016) Crabapple fruit extracts lower hypercholesterolaemia in high-fat diet-induced obese mice. Journal of Functional Foods 27, pages 416-428.
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So Hyun Han, Bong Gyu Kim, Jeong A. Yoon, Youhoon Chong & Joong-Hoon Ahn. (2014) Synthesis of Flavonoid O -Pentosides by Escherichia coli through Engineering of Nucleotide Sugar Pathways and Glycosyltransferase . Applied and Environmental Microbiology 80:9, pages 2754-2762.
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Min Zhao, Jun Xu, Dawei Qian, Jianming Guo, Shu Jiang, Er-xin Shang, Jin-ao Duan, Jing Yang & Le-yue Du. (2014) Ultra performance liquid chromatography/quadrupole-time-of-flight mass spectrometry for determination of avicularin metabolites produced by a human intestinal bacterium. Journal of Chromatography B 949-950, pages 30-36.
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Veda Eswarappa & Sujata K. BhatiaVeda Eswarappa & Sujata K. Bhatia. 2013. Naturally Based Biomaterials and Therapeutics. Naturally Based Biomaterials and Therapeutics 27 79 .
Luiza Maria de Magalhães Camargo, Jean-Pierre Férézou, Luzineide Wanderley Tinoco, Carlos Roland Kaiser & Sônia Soares Costa. (2012) Flavonoids from Mimosa xanthocentra (Leguminosae: Mimosoideae) and molecular modeling studies for isovitexin-2″-O-α-l-rhamnopyranoside rotamers. Phytochemistry Letters 5:3, pages 427-431.
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Khairunnuur Fairuz Azman, Zulkhairi Amom, Azrina Azlan, Norhaizan Mohd Esa, Rasadah Mat Ali, Zamree Md Shah & Khairul Kamilah Abdul Kadir. (2011) Antiobesity effect of Tamarindus indica L. pulp aqueous extract in high-fat diet-induced obese rats. Journal of Natural Medicines 66:2, pages 333-342.
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Chia-Yu Liu, Ying-Chih Lin, Jeng-Shyan Deng, Jung-Chun Liao, Wen-Huang Peng & Guan-Jhong Huang. (2012) Antioxidant, Anti-inflammatory, and Antiproliferative Activities of Taxillus sutchuenensis . The American Journal of Chinese Medicine 40:02, pages 335-348.
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Lin Zhang, Anjaneya S. Ravipati, Sundar Rao Koyyalamudi, Sang Chul Jeong, Narsimha Reddy, Paul T. Smith, John Bartlett, Kirubakaran Shanmugam, Gerald Münch & Ming Jie Wu. (2011) Antioxidant and Anti-inflammatory Activities of Selected Medicinal Plants Containing Phenolic and Flavonoid Compounds. Journal of Agricultural and Food Chemistry 59:23, pages 12361-12367.
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Chih-Chun Wen, Lie-Fen Shyur, Jia-Tsrong Jan, Po-Huang Liang, Chih-Jung Kuo, Palanisamy Arulselvan, Jin-Bin Wu, Sheng-Chu Kuo & Ning-Sun Yang. (2011) Traditional Chinese medicine herbal extracts of Cibotium barometz, Gentiana scabra, Dioscorea batatas, Cassia tora, and Taxillus chinensis inhibit SARS-CoV replication. Journal of Traditional and Complementary Medicine 1:1, pages 41-50.
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Qiuping Chen, Xiaowei Luo, Xiaofeng Ma, Tianjia Jiang, Baiyi Lu, Jianfu Shen & Ying Zhang. (2011) Fatty Acid Synthase Inhibitors Separated from Oiltea Camellia by High-Speed Counter-Current Chromatography. Journal of Food Science 76:5, pages C750-C754.
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Wei-xi Tian, Xiao-feng Ma, Shu-yan Zhang, Ying-hui Sun & Bing-hui Li. (2011) Fatty acid synthase inhibitors from plants and their potential application in the prevention of metabolic syndrome. Clinical Oncology and Cancer Research 8:1, pages 1-9.
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Isabel Baiges, Johan Palmfeldt, Cinta Bladé, Niels Gregersen & Lluís Arola. (2010) Lipogenesis Is Decreased by Grape Seed Proanthocyanidins According to Liver Proteomics of Rats Fed a High Fat Diet. Molecular & Cellular Proteomics 9:7, pages 1499-1513.
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Yan Wang, Min Deng, Shu-Yan Zhang, Zhe-Kun Zhou & Wei-Xi Tian. (2008) Parasitic loranthus from Loranthaceae rather than Viscaceae potently inhibits fatty acid synthase and reduces body weight in mice. Journal of Ethnopharmacology 118:3, pages 473-478.
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Wen-Hua Zhao, Chun-Yang Zhao, Li-Fang Gao, Fei-Fei Feng, Wen Gao, Zhen-Liang Chen, Feng Zhang, Li-Ge Cao, Xiao-Yu Bi, Yue Chen, Qi-Yao Zhu & Ying-Xia Zhang. (2008) The novel inhibitory effect of Pangdahai on fatty acid synthase. IUBMB Life 60:3, pages 185-194.
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