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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 38, 2023 - Issue 1
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Research Paper

Design, synthesis and evaluation of 2, 6, 8-substituted Imidazopyridine derivatives as potent PI3Kα inhibitors

Rui Chena Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, Guiyang, ChinaView further author information
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Zhongyuan Wangb Department of Pharmacy, Guizhou Provincial People’s Hospital, Guiyang, ChinaView further author information
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Lijie Simac Department of Hematology and Oncology, The Affiliated Shaoyang Hospital, Hengyang Medical School, University of South China (Shaoyang Central Hospital), ChinaView further author information
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Hu Chenga Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, Guiyang, ChinaView further author information
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Bilan Luoa Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, Guiyang, ChinaView further author information
,
Jianta Wanga Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, Guiyang, ChinaView further author information
,
Bing Guod Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, ChinaView further author information
,
Shunyi Maoe School of Pharmaceutical Sciences, Guizhou University, Guiyang, ChinaView further author information
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Zhixu Zhoue School of Pharmaceutical Sciences, Guizhou University, Guiyang, ChinaView further author information
,
Jingang Penga Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, Guiyang, ChinaView further author information
,
Lei Tanga Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, Guiyang, ChinaView further author information
,
Xinfu Liuc Department of Hematology and Oncology, The Affiliated Shaoyang Hospital, Hengyang Medical School, University of South China (Shaoyang Central Hospital), ChinaCorrespondence[email protected]
View further author information
&
Weike Liaoa Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, Guiyang, ChinaCorrespondence[email protected]
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Article: 2155638 | Received 21 Sep 2022, Accepted 01 Dec 2022, Published online: 17 Jan 2023

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Lijie Sima, Zhongyuan Wang, Ling Yu, Youli Hou, Dongsheng Zhao, Bilan Luo, Weike Liao & Xinfu Liu. (2024) Discovery of LAH-1 as potent c-Met inhibitor for the treatment of non-small cell lung cancer. Journal of Enzyme Inhibition and Medicinal Chemistry 39:1.
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Moataz A. Shaldam, Hadia Almahli, Andrea Angeli, Rehab Mustafa Badi, Eman F. Khaleel, Abdelrahman I. Zain-Alabdeen, Zainab M. Elsayed, Eslam B. Elkaeed, Rofaida Salem, Claudiu T. Supuran, Wagdy M. Eldehna & Haytham O. Tawfik. (2023) Discovery of sulfonamide-tethered isatin derivatives as novel anticancer agents and VEGFR-2 inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Articles from other publishers (2)

Baban Mohan Mulik, Noopur Srivastava & Dhananjay Pendharkar. (2024) Synthesis, Biological Evaluation, Molecular Docking and ADME Profiling of Methylpiperidin‐4‐ylphenyl‐nicotinamide Derivatives. ChemistrySelect 9:14.
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Vinay Kumar Mishra, Ghanshyam Tiwari, Ashish Khanna, Yogesh Yadav & Ram Sagar. (2024) Base‐Induced Annulation of Glycal‐Derived α‐iodopyranone with 2‐Aminopyrimidinones: Access to Chiral Imidazopyrimidinones. European Journal of Organic Chemistry 27:8.
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