1,019
Views
44
CrossRef citations to date
0
Altmetric
Review

Calcium phosphate: a substitute for aluminum adjuvants?

, , &
Pages 289-299 | Received 12 May 2016, Accepted 30 Sep 2016, Published online: 24 Oct 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Yahua Lin, Xin Wang, Xiaofen Huang, Jun Zhang, Ningshao Xia & Qinjian Zhao. (2017) Calcium phosphate nanoparticles as a new generation vaccine adjuvant. Expert Review of Vaccines 16:9, pages 895-906.
Read now

Articles from other publishers (43)

Sivakumar S. Moni, Siddig Ibrahim Abdelwahab, Aamena Jabeen, Mohamed Eltaib Elmobark, Duaa Aqaili, Gassem Ghoal, Bassem Oraibi, Abdulla Mohammed Farasani, Ahmed Ali Jerah, Mahdi Mohammed A. Alnajai & Abdul Majeed Hamad Mohammad Alowayni. (2023) Advancements in Vaccine Adjuvants: The Journey from Alum to Nano Formulations. Vaccines 11:11, pages 1704.
Crossref
Tanjilur Rahman, Ayan Das, Mehedy Hasan Abir, Iqbal Hossain Nafiz, Aar Rafi Mahmud, Md. Rifat Sarker, Talha Bin Emran & Mohammad Mahmudul Hassan. (2023) Cytokines and their role as immunotherapeutics and vaccine Adjuvants: The emerging concepts. Cytokine 169, pages 156268.
Crossref
Li Zhuang, Zhaoyang Ye, Linsheng Li, Ling Yang & Wenping Gong. (2023) Next-Generation TB Vaccines: Progress, Challenges, and Prospects. Vaccines 11:8, pages 1304.
Crossref
Anastasia Yu. Teterina, Vladislav V. Minaychev, Polina V. Smirnova, Margarita I. Kobiakova, Igor V. Smirnov, Roman S. Fadeev, Alexey A. Egorov, Artem A. Ashmarin, Kira V. Pyatina, Anatoliy S. Senotov, Irina S. Fadeeva & Vladimir S. Komlev. (2023) Injectable Hydrated Calcium Phosphate Bone-like Paste: Synthesis, In Vitro, and In Vivo Biocompatibility Assessment. Technologies 11:3, pages 77.
Crossref
Bruno Henrique Costa, Alisson Kennedy Rezende, Lais Costa, Gabrielle Fernanda Monteiro Neves, Antônio Carlos Shimano, Álvaro de Oliveira Penoni, Claudia Rocha Carvalho, Raquel Alves Costa & Erika Costa de Alvarenga. (2023) Systemic effects of oral tolerance in bone healing. Scientific Reports 13:1.
Crossref
Mahendran Thangavel & Renold Elsen Selvam. (2022) Review of Physical, Mechanical, and Biological Characteristics of 3D-Printed Bioceramic Scaffolds for Bone Tissue Engineering Applications. ACS Biomaterials Science & Engineering 8:12, pages 5060-5093.
Crossref
Nadezhda Angelova, Savina Koleva, Marco Kostadinov & Georgi Yordanov. (2022) Preparation, characterization and protein adsorption properties of nanostructured magnesium whitlockite. Journal of Materials Science 57:47, pages 21571-21582.
Crossref
Hossein Jafari-Nodoushan, Somayeh Mojtabavi, Mohammad Ali Faramarzi & Nasrin Samadi. (2022) Organic-inorganic hybrid nanoflowers: The known, the unknown, and the future. Advances in Colloid and Interface Science 309, pages 102780.
Crossref
Lazar D. Nesovic, Akhilesh K. Shakya & Harvinder S. Gill. (2022) Treating allergies via skin – Recent advances in cutaneous allergen immunotherapy. Advanced Drug Delivery Reviews 190, pages 114458.
Crossref
Natalia Rudenko, Anna Karatovskaya, Anna Zamyatina, Anna Shepelyakovskaya, Svetlana Semushina, Fedor Brovko, Anna Shpirt, Vladimir Torgov, Natalia Kolotyrkina, Alexandr Zinin, Anastasiya Kasimova, Andrei Perepelov, Mikhail Shneider & Yuriy Knirel. (2022) Immune Response to Conjugates of Fragments of the Type K9 Capsular Polysaccharide of Acinetobacter baumannii with Carrier Proteins. Microbiology Spectrum 10:5.
Crossref
Qin Zeng, Ruiqi Wang, Yuchen Hua, Hongfeng Wu, Xuening Chen, You-cai Xiao, Qiang Ao, Xiangdong Zhu & Xingdong Zhang. (2022) Hydroxyapatite nanoparticles drive the potency of Toll-like receptor 9 agonist for amplified innate and adaptive immune response. Nano Research 15:10, pages 9286-9297.
Crossref
Sergey V. Dorozhkin. (2022) Calcium Orthophosphate (CaPO4)-Based Bioceramics: Preparation, Properties, and Applications. Coatings 12:10, pages 1380.
Crossref
Loïc Angrand, Jean-Daniel Masson, Alberto Rubio-Casillas, Marika Nosten-Bertrand & Guillemette Crépeaux. (2022) Inflammation and Autophagy: A Convergent Point between Autism Spectrum Disorder (ASD)-Related Genetic and Environmental Factors: Focus on Aluminum Adjuvants. Toxics 10:9, pages 518.
Crossref
David A. González-Martínez, Gustavo González Ruíz, María del Carmen Luzardo Lorenzo, Fernando Bordallo-León, Yerandy Hechavarría Luna, Yadira Cazañas Quintana, Eduardo González-Martínez, Kalet León, Addys González Palomo, Judey Aymed García Artalejo & Jose Moran-Mirabal. (2022) Hydroxyapatite Nanoparticles as a Potential Long-Term Treatment of Cancer of Epithelial Origin. ACS Applied Nano Materials 5:5, pages 6159-6170.
Crossref
Jia Tan, Binbin Ding, Bo Teng, Ping'an Ma & Jun Lin. (2022) Understanding Structure–Function Relationships of Nanoadjuvants for Enhanced Cancer Vaccine Efficacy. Advanced Functional Materials 32:16, pages 2111670.
Crossref
Alex Langford, Michael Bruchsaler & Manish Gupta. 2022. Practical Aspects of Vaccine Development. Practical Aspects of Vaccine Development 225 266 .
Farrhana Ziana Firdaus, Mariusz Skwarczynski & Istvan Toth. 2022. Vaccine Design. Vaccine Design 145 178 .
Prashamsa Koirala, Sahra Bashiri, Istvan Toth & Mariusz Skwarczynski. 2022. Vaccine Design. Vaccine Design 309 338 .
Zhe Sun, Wenyi Li, Jason C. Lenzo, James A. Holden, Michael J. McCullough, Andrea J. O’Connor & Neil M. O’Brien-Simpson. (2021) The Potential of Calcium Phosphate Nanoparticles as Adjuvants and Vaccine Delivery Vehicles. Frontiers in Materials 8.
Crossref
Lei Zhang, Zhihui Liang, Chen Chen, Xuecheng Yang, Duo Fu, Hang Bao, Min Li, Shuting Shi, Ge Yu, Yixuan Zhang, Caiqiao Zhang, Weiting Zhang, Changying Xue & Bingbing Sun. (2021) Engineered Hydroxyapatite Nanoadjuvants with Controlled Shape and Aspect Ratios Reveal Their Immunomodulatory Potentials. ACS Applied Materials & Interfaces 13:50, pages 59662-59672.
Crossref
Tadech Boonpiyathad, Mongkol Lao-Araya, Chirawat Chiewchalermsri, Sasipa Sangkanjanavanich & Hideaki Morita. (2021) Allergic Rhinitis: What Do We Know About Allergen-Specific Immunotherapy?. Frontiers in Allergy 2.
Crossref
Zhongyuan Guo, Luke J. Kubiatowicz, Ronnie H. Fang & Liangfang Zhang. (2021) Nanotoxoids: Biomimetic Nanoparticle Vaccines against Infections. Advanced Therapeutics 4:8, pages 2100072.
Crossref
William Walkowski, Justin Bassett, Manmeet Bhalla, Blaine A. Pfeifer & Elsa N. Bou Ghanem. (2021) Intranasal Vaccine Delivery Technology for Respiratory Tract Disease Application with a Special Emphasis on Pneumococcal Disease. Vaccines 9:6, pages 589.
Crossref
Kailash C. Petkar, Suyash M. Patil, Sandip S. Chavhan, Kan Kaneko, Krutika K. Sawant, Nitesh K. Kunda & Imran Y. Saleem. (2021) An Overview of Nanocarrier-Based Adjuvants for Vaccine Delivery. Pharmaceutics 13:4, pages 455.
Crossref
Minghui Li, Mengmeng Qin, Ge Song, Hailiang Deng, Dakuan Wang, Xueqing Wang, Wenbing Dai, Bing He, Hua Zhang & Qiang Zhang. (2021) A biomimetic antitumor nanovaccine based on biocompatible calcium pyrophosphate and tumor cell membrane antigens. Asian Journal of Pharmaceutical Sciences 16:1, pages 97-109.
Crossref
Irache Echeverría, Ricardo de Miguel, Javier Asín, Ana Rodríguez-Largo, Antonio Fernández, Marta Pérez, Damián de Andrés, Lluís Luján & Ramsés Reina. (2020) Replication of Small Ruminant Lentiviruses in Aluminum Hydroxide-Induced Granulomas in Sheep: a Potential New Factor for Viral Dissemination. Journal of Virology 95:2.
Crossref
Pei Cao, Felicity Y. Han, Lisbeth Grøndahl, Zhi Ping Xu & Li Li. (2020) Enhanced Oral Vaccine Efficacy of Polysaccharide-Coated Calcium Phosphate Nanoparticles. ACS Omega 5:29, pages 18185-18197.
Crossref
Montserrat Alvaro‐Lozano, Cezmi A. Akdis, Mubeccel Akdis, Cherry Alviani, Elisabeth Angier, Stefania Arasi, Lisa Arzt‐Gradwohl, Domingo Barber, Raphaëlle Bazire, Ozlem Cavkaytar, Pasquale Comberiati, Stephanie Dramburg, Stephen R. Durham, Aarif O. Eifan, Leandra Forchert, Susanne Halken, Max Kirtland, Umut C. Kucuksezer, Janice A. Layhadi, Paolo Maria Matricardi, Antonella Muraro, Cevdet Ozdemir, Giovanni Battista Pajno, Oliver Pfaar, Ekaterina Potapova, Carmen Riggioni, Graham Roberts, Pablo Rodríguez del Río, Mohamed H. Shamji, Gunter J. Sturm & Marta Vazquez‐Ortiz. (2020) Allergen Immunotherapy in Children User’s Guide. Pediatric Allergy and Immunology 31:S25, pages 1-101.
Crossref
Erika Jensen‐Jarolim, Martin F. Bachmann, Sergio Bonini, Lars Jacobsen, Marek Jutel, Ludger Klimek, Vera Mahler, Ralph Mösges, Philippe Moingeon, Robyn E. O´Hehir, Oscar Palomares, Oliver Pfaar, Harald Renz, Claudio Rhyner, Franziska Roth‐Walter, Michael Rudenko, Johannes Savolainen, Carsten B. Schmidt‐Weber, Claudia Traidl‐Hoffmann & Thomas Kündig. (2020) State‐of‐the‐art in marketed adjuvants and formulations in Allergen Immunotherapy: A position paper of the European Academy of Allergy and Clinical Immunology (EAACI). Allergy 75:4, pages 746-760.
Crossref
Etsuro Nanishi, David J. Dowling & Ofer Levy. (2020) Toward precision adjuvants: optimizing science and safety. Current Opinion in Pediatrics 32:1, pages 125-138.
Crossref
Willi Paul & Chandra P. Sharma. 2020. Biointegration of Medical Implant Materials. Biointegration of Medical Implant Materials 333 373 .
Srijanaki Paravastu Pattarabhiran, Anjana Saju, Kanchan Rajendra Sonawane, Raghuraman Manimaran, Shubhmita Bhatnagar, Girdhari Roy, Radha Balkrishna Kulkarni & Venkata Vamsi Krishna Venuganti. (2019) Dissolvable Microneedle-Mediated Transcutaneous Delivery of Tetanus Toxoid Elicits Effective Immune Response. AAPS PharmSciTech 20:7.
Crossref
Romain K. Gherardi, Guillemette Crépeaux & François-Jérome Authier. (2019) Myalgia and chronic fatigue syndrome following immunization: macrophagic myofasciitis and animal studies support linkage to aluminum adjuvant persistency and diffusion in the immune system. Autoimmunity Reviews 18:7, pages 691-705.
Crossref
Shuting Shi, Haoru Zhu, Xinyu Xia, Zhihui Liang, Xuehu Ma & Bingbing Sun. (2019) Vaccine adjuvants: Understanding the structure and mechanism of adjuvanticity. Vaccine 37:24, pages 3167-3178.
Crossref
J Wallis, D P Shenton & R C Carlisle. (2019) Novel approaches for the design, delivery and administration of vaccine technologies. Clinical and Experimental Immunology 196:2, pages 189-204.
Crossref
M. Abkar, S. Alamian & N. Sattarahmady. (2019) A comparison between adjuvant and delivering functions of calcium phosphate, aluminum hydroxide and chitosan nanoparticles, using a model protein of Brucella melitensis Omp31. Immunology Letters 207, pages 28-35.
Crossref
Danina Krajišnik, Tanja Ilić, Ines Nikolić & Snežana Savić. (2019) Established and advanced adjuvants in vaccines' formulation: Mineral adsorbents, nanoparticulate carriers and microneedle delivery systems. Arhiv za farmaciju 69:6, pages 420-451.
Crossref
Ivan Ivanovski, Ana Ivanovski, Dimitrije Nikolić & Petar Ivanovski. (2019) Aluminium in brain tissue in autism. Journal of Trace Elements in Medicine and Biology 51, pages 138-140.
Crossref
Ting Liu, Rui Qian, Qingchuan Liu, Tingni Wu & Jialong Chen. 2018. Immunization - Vaccine Adjuvant Delivery System and Strategies. Immunization - Vaccine Adjuvant Delivery System and Strategies.
Andreas Svensson, Tove Sandberg, Peter Siesjö & Håkan Eriksson. (2017) Sequestering of damage-associated molecular patterns (DAMPs): a possible mechanism affecting the immune-stimulating properties of aluminium adjuvants. Immunologic Research 65:6, pages 1164-1175.
Crossref
Amy S McKee & Philippa Marrack. (2017) Old and new adjuvants. Current Opinion in Immunology 47, pages 44-51.
Crossref
Martin Himly, Robert Mills-Goodlet, Mark Geppert & Albert Duschl. (2017) Nanomaterials in the Context of Type 2 Immune Responses—Fears and Potentials. Frontiers in Immunology 8.
Crossref
R. Brehler. (2017) AdjuvanzienAdjuvants. Der Hautarzt 68:4, pages 292-296.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.