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Original Article

A high Nugent score but not a positive culture for genital mycoplasmas is a risk factor for spontaneous preterm birth

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Pages 212-217 | Received 02 Apr 2007, Accepted 20 Sep 2008, Published online: 07 Jul 2009

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Read on this site (6)

Yasuhiro Miyoshi, Sachie Suga, So Sugimi, Nao Kurata, Hiroshi Yamashita & Ichiro Yasuhi. (2022) Vaginal Ureaplasma urealyticum or Mycoplasma hominis and preterm delivery in women with threatened preterm labor. The Journal of Maternal-Fetal & Neonatal Medicine 35:5, pages 878-883.
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Ji Y. Kim, Ji-Hee Sung, Kylie Hae-Jin Chang, Suk-Joo Choi, Soo-young Oh, Cheong-Rae Roh & Jong-Hwa Kim. (2017) Abnormal vaginal colonization by gram-negative bacteria is significantly higher in pregnancy conceived through infertility treatment compared to natural pregnancy. The Journal of Maternal-Fetal & Neonatal Medicine 30:5, pages 556-561.
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Gilbert GG Donders, Jana Zodzika & Dace Rezeberga. (2014) Treatment of bacterial vaginosis: what we have and what we miss. Expert Opinion on Pharmacotherapy 15:5, pages 645-657.
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Dong-Wook Kwak, Han-Sung Hwang, Ja-Young Kwon, Yong-Won Park & Young-Han Kim. (2014) Co-infection with vaginal Ureaplasma urealyticum and Mycoplasma hominis increases adverse pregnancy outcomes in patients with preterm labor or preterm premature rupture of membranes. The Journal of Maternal-Fetal & Neonatal Medicine 27:4, pages 333-337.
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Seung Mi Lee, Roberto Romero, Jeong Woo Park, Sun Min Kim, Chan-Wook Park, Steven J. Korzeniewski, Tinnakorn Chaiworapongsa & Bo Hyun Yoon. (2012) The clinical significance of a positive Amnisure test in women with preterm labor and intact membranes. The Journal of Maternal-Fetal & Neonatal Medicine 25:9, pages 1690-1698.
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Maria Breugelmans, Ellen Vancutsem, Anne Naessens, Monica Laubach & Walter Foulon. (2010) Association of abnormal vaginal flora and Ureaplasma species as risk factors for preterm birth: a cohort study. Acta Obstetricia et Gynecologica Scandinavica 89:2, pages 256-260.
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Articles from other publishers (30)

Erina Matsuda, Kazuhide Takada, Osamu Kobayashi, Takahiro Nakajima, Yuji Ikeda, Mikiko Asai-Sato, Kaori Kawakami, Atsushi Komatsu, Fumihisa Chishima, Shihoko Komine-Aizawa, Satoshi Hayakawa & Kei Kawana. (2023) Pathological roles of antimicrobial peptides and pro-inflammatory factors secreted from the cervical epithelium in Gardnerella vaginalis-abundant vaginal flora in pregnancy. Journal of Reproductive Immunology 156, pages 103797.
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GKP Cunha, LB Bastos, SF Freitas, RC Cavalli & SM Quintana. (2021) Genital mycoplasma infection and spontaneous preterm birth outcome: a prospective cohort study. BJOG: An International Journal of Obstetrics & Gynaecology 129:2, pages 273-281.
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Kyung Joon Oh, Roberto Romero, Jee Yoon Park, Joon-Seok Hong & Bo Hyun Yoon. (2019) The earlier the gestational age, the greater the intensity of the intra-amniotic inflammatory response in women with preterm premature rupture of membranes and amniotic fluid infection by Ureaplasma species . Journal of Perinatal Medicine 47:5, pages 516-527.
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Марина Власова, Marina Vlasova, Стефания Супрун, Stefaniya Suprun, Ольга Морозова, Olga Morozova, Н Талаева & N Talaeva. (2018) INFLUENCE OF THE MASSIVENESS OF INFECTION OF THE GENITAL TRACT WITH UROGENITAL MYCOPLASMAS ON THE COURSE AND OUTCOMES OF PREGNANCY IN WOMEN OF THE AMUR REGION. Bulletin physiology and pathology of respiration 1:70, pages 61-67.
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Maria Agnese Latino, Giovanni Botta, Claudia Badino, Daniela De Maria, Annalisa Petrozziello, Alessandra Sensini & Christian Leli. (2018) Association between genital mycoplasmas, acute chorioamnionitis and fetal pneumonia in spontaneous abortions. Journal of Perinatal Medicine 46:5, pages 503-508.
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Kirsten Glaser, Christine Silwedel, Ana Maria Waaga-Gasser, Birgit Henrich, Markus Fehrholz, Heike Claus & Christian P. Speer. (2018) Ureaplasma isolates differentially modulate growth factors and cell adhesion molecules in human neonatal and adult monocytes. Cytokine 105, pages 45-48.
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Nathalia Mayumi Noda-Nicolau, Jossimara Polettini, Márcia Guimarães da Silva, Morgan R. Peltier & Ramkumar Menon. (2018) Polybacterial stimulation suggests discrete IL-6/IL-6R signaling in human fetal membranes: Potential implications on IL-6 bioactivity. Journal of Reproductive Immunology 126, pages 60-68.
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Kirsten Glaser, Christine Silwedel, Markus Fehrholz, Birgit Henrich, Ana Maria Waaga-Gasser, Heike Claus & Christian P. Speer. (2018) Ureaplasma isolates stimulate pro-inflammatory CC chemokines and matrix metalloproteinase-9 in neonatal and adult monocytes. PLOS ONE 13:3, pages e0194514.
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David Taylor-Robinson. (2017) Mollicutes in vaginal microbiology: Mycoplasma hominis, Ureaplasma urealyticum, Ureaplasma parvum and Mycoplasma genitalium. Research in Microbiology 168:9-10, pages 875-881.
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Gilbert G.G. Donders, Kateryna Ruban, Gert Bellen & Ljubomir Petricevic. (2017) Mycoplasma/Ureaplasma infection in pregnancy: to screen or not to screen. Journal of Perinatal Medicine 45:5.
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Emma L. Sweeney, Samantha J. Dando, Suhas G. Kallapur & Christine L. Knox. (2017) The Human Ureaplasma Species as Causative Agents of Chorioamnionitis. Clinical Microbiology Reviews 30:1, pages 349-379.
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G. Kayem, E. Lorthe & M. Doret. (2016) Prise en charge d’une menace d’accouchement prématuré. Journal de Gynécologie Obstétrique et Biologie de la Reproduction 45:10, pages 1364-1373.
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Gilbert G.G. Donders, Francesca Donders, Gert Bellen, Christophe Depuydt, Natalie Eggermont, Thirsa Michiels, John Lule & Jacobat Byamughisa. (2016) Screening for abnormal vaginal microflora by self-assessed vaginal pH does not enable detection of sexually transmitted infections in Ugandan women. Diagnostic Microbiology and Infectious Disease 85:2, pages 227-230.
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C. Cox, A. P. Watt, J. P. McKenna & P. V. Coyle. (2016) Mycoplasma hominis and Gardnerella vaginalis display a significant synergistic relationship in bacterial vaginosis. European Journal of Clinical Microbiology & Infectious Diseases 35:3, pages 481-487.
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P Kokkayil & B Dhawan. (2015) Ureaplasma: Current perspectives. Indian Journal of Medical Microbiology 33:2, pages 205-214.
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Demelza J. Ireland & Jeffrey A. Keelan. (2014) The Maternal Serological Response to Intrauterine Ureaplasma sp. Infection and Prediction of Risk of Pre-Term Birth. Frontiers in Immunology 5.
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Roberto Romero, Sonia S Hassan, Pawel Gajer, Adi L Tarca, Douglas W Fadrosh, Janine Bieda, Piya Chaemsaithong, Jezid Miranda, Tinnakorn Chaiworapongsa & Jacques Ravel. (2014) The vaginal microbiota of pregnant women who subsequently have spontaneous preterm labor and delivery and those with a normal delivery at term. Microbiome 2:1.
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William A. Agger, Danish Siddiqui, Steven D. Lovrich, Steven M. Callister, Andrew J. Borgert, Kenneth W. Merkitch, Tina C. Mason, Dennis J. Baumgardner, James K. Burmester, Sanjay K. Shukla, Joseph D. Welter, Katharina S. Stewart, M.J. Washburn & Howard H. Bailey. (2014) Epidemiologic Factors and Urogenital Infections Associated With Preterm Birth in a Midwestern U.S. Population. Obstetrics & Gynecology 124:5, pages 969-977.
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Ahmad El-Sheikhah, Iman Elzahaby, Osama El-Shenofy & Iman Wali. (2014) Correlation between increased vaginal pH and abnormalities in the vaginal flora with respect to cervical length and their role in the prediction of preterm birth. Evidence Based Womenʼs Health Journal 4:2, pages 99-104.
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Romina Capoccia, Gilbert Greub & David Baud. (2013) Ureaplasma urealyticum, Mycoplasma hominis and adverse pregnancy outcomes. Current Opinion in Infectious Diseases 26:3, pages 231-240.
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Brenna L. Anderson, Hector Mendez-Figueroa, Joshua D. Dahlke, Christina Raker, Sharon L. Hillier & Susan Cu-Uvin. (2013) Pregnancy-induced changes in immune protection of the genital tract: defining normal. American Journal of Obstetrics and Gynecology 208:4, pages 321.e1-321.e9.
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Seong Jin Choi, Soon Deok Park, In Ho Jang, Young Uh & Anna Lee. (2012) The Prevalence of Vaginal Microorganisms in Pregnant Women with Preterm Labor and Preterm Birth. Annals of Laboratory Medicine 32:3, pages 194-200.
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J.-M. Bohbot & J.-P. Lepargneur. (2012) La vaginose en 2011 : encore beaucoup d’interrogations. Gynécologie Obstétrique & Fertilité 40:1, pages 31-36.
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Cristina Ros, Montserrat Palacio, Jordi Bosch, Teresa Cobo, Mònica Martínez-Terrón & Eduard Gratacós. (2011) Resultados perinatales en amenazas de parto prematuro con colonización endocervical por Ureaplasma urealyticum. Progresos de Obstetricia y Ginecología 54:9, pages 441-445.
Crossref
Ronald F. Lamont, Chia-Ling Nhan-Chang, Jack D. Sobel, Kimberly Workowski, Agustin Conde-Agudelo & Roberto Romero. (2011) Treatment of abnormal vaginal flora in early pregnancy with clindamycin for the prevention of spontaneous preterm birth: a systematic review and metaanalysis. American Journal of Obstetrics and Gynecology 205:3, pages 177-190.
Crossref
Camila Marconi, Bruna Ribeiro de Andrade Ramos, José Carlos Peraçoli, Gilbert G. G. Donders & Márcia Guimarães da Silva. (2011) Amniotic Fluid Interleukin-1 Beta and Interleukin-6, but not Interleukin-8 Correlate with Microbial Invasion of the Amniotic Cavity in Preterm Labor. American Journal of Reproductive Immunology 65:6, pages 549-556.
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Byoung Jae Kim, Roberto Romero, Seung Mi Lee, Chan-Wook Park, Joong Shin Park, Jong Kwan Jun & Bo Hyun Yoon. (2011) Clinical significance of oligohydramnios in patients with preterm labor and intact membranes*,**. Journal of Perinatal Medicine 39:2.
Crossref
D Taylor-Robinson & RF Lamont. (2011) Mycoplasmas in pregnancy. BJOG: An International Journal of Obstetrics & Gynaecology 118:2, pages 164-174.
Crossref
Gilbert Donders. (2010) Diagnosis and Management of Bacterial Vaginosis and Other Types of Abnormal Vaginal Bacterial Flora: A Review. Obstetrical & Gynecological Survey 65:7, pages 462-473.
Crossref
Bryan Larsen & Joseph Hwang. (2010) Mycoplasma , Ureaplasma , and Adverse Pregnancy Outcomes: A Fresh Look . Infectious Diseases in Obstetrics and Gynecology 2010, pages 1-7.
Crossref

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