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Original Article

The impact of ibuprofen or indomethacin on renal drug clearance in neonates

, MD, PhD
Pages 88-91 | Received 01 Jun 2009, Accepted 08 Jul 2009, Published online: 23 Oct 2009

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Johan C. A. de Klerk, Nanda van Paassen, Ingrid M. van Beynum, Robert B. Flint, Irwin K. M. Reiss & Sinno H. P. Simons. (2021) Ibuprofen treatment after the first days of life in preterm neonates with patent ductus arteriosus. The Journal of Maternal-Fetal & Neonatal Medicine 34:15, pages 2411-2417.
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Franco Bagnoli, Annalisa Rossetti, Gabriele Messina, Annalisa Mori, Martina Casucci & Barbara Tomasini. (2013) Treatment of patent ductus arteriosus (PDA) using ibuprofen: renal side-effects in VLBW and ELBW newborns. The Journal of Maternal-Fetal & Neonatal Medicine 26:4, pages 423-429.
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Karel Allegaert, Maike Kuppens, Djalila Mekahli, Elena Levtchenko, Florent Vanstapel, Christine Vanhole & John N. van den Anker. (2012) Creatinine reference values in ELBW infants: impact of quantification by Jaffe or enzymatic method. The Journal of Maternal-Fetal & Neonatal Medicine 25:9, pages 1678-1681.
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Costantino Romagnoli, Iliana Bersani, Serena Antonia Rubortone, Serafina Lacerenza & Maria Pia De Carolis. (2011) Current evidence on the safety profile of NSAIDs for the treatment of PDA. The Journal of Maternal-Fetal & Neonatal Medicine 24:sup3, pages 10-13.
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Articles from other publishers (16)

Sara N. Salerno, Yuting Liao, Wesley Jackson, Rachel G. Greenberg, Cameron J. McKinzie, Ashley McCallister, Daniel K. Benjamin, Matthew M. Laughon, Keia Sanderson, Reese H. Clark & Daniel Gonzalez. (2021) Association between Nephrotoxic Drug Combinations and Acute Kidney Injury in the Neonatal Intensive Care Unit. The Journal of Pediatrics 228, pages 213-219.
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J E Constance, D Reith, R M Ward, A Balch, C Stockmann, E K Korgenski, E A Thorell & C M T Sherwin. (2017) Risk of nonsteroidal anti-inflammatory drug-associated renal dysfunction among neonates diagnosed with patent ductus arteriosus and treated with gentamicin. Journal of Perinatology 37:10, pages 1093-1102.
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Nazario D Rivera-Chaparro, Michael Cohen-Wolkowiez & Rachel G Greenberg. (2017) Dosing antibiotics in neonates: review of the pharmacokinetic data. Future Microbiology 12:11, pages 1001-1016.
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Sook Hee An. (2017) Contributing Factors on Pharmacokinetic Variability in Critically Ill Neonates. Korean Journal of Clinical Pharmacy 27:2, pages 63-68.
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Karel Allegaert & John N. van den Anker. 2017. Neonatal Pain. Neonatal Pain 227 238 .
Mélanie Wilbaux, Aline Fuchs, Janko Samardzic, Frédérique Rodieux, Chantal Csajka, Karel Allegaert, Johannes N. van den Anker & Marc Pfister. (2016) Pharmacometric Approaches to Personalize Use of Primarily Renally Eliminated Antibiotics in Preterm and Term Neonates. The Journal of Clinical Pharmacology 56:8, pages 909-935.
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Frederique Rodieux, Melanie Wilbaux, Johannes N. van den Anker & Marc Pfister. (2015) Effect of Kidney Function on Drug Kinetics and Dosing in Neonates, Infants, and Children. Clinical Pharmacokinetics 54:12, pages 1183-1204.
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Anna Girardi, Emanuel Raschi, Silvia Galletti, Elisabetta Poluzzi, Giacomo Faldella, Karel Allegaert & Fabrizio De Ponti. (2015) Drug-Induced Renal Damage in Preterm Neonates: State of the Art and Methods for Early Detection. Drug Safety 38:6, pages 535-551.
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Michiel F Schreuder, Ruud R G Bueters & Karel Allegaert. (2013) The interplay between drugs and the kidney in premature neonates. Pediatric Nephrology 29:11, pages 2083-2091.
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Carol A. Botwinski & Gabriella A. Falco. (2014) Transition to Postnatal Renal Function. Journal of Perinatal & Neonatal Nursing 28:2, pages 150-154.
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Roosmarijn F. W. De Cock, Karel Allegaert, Catherine M. T. Sherwin, Elisabet I. Nielsen, Matthijs de Hoog, Johannes N. van den Anker, Meindert Danhof & Catherijne A. J. Knibbe. (2013) A Neonatal Amikacin Covariate Model Can Be Used to Predict Ontogeny of Other Drugs Eliminated Through Glomerular Filtration in Neonates. Pharmaceutical Research 31:3, pages 754-767.
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Gian Maria Pacifici. (2013) Clinical Pharmacology of Indomethacin in Preterm Infants: Implications in Patent Ductus Arteriosus Closure. Pediatric Drugs 15:5, pages 363-376.
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Robin B. Knobel & Jennifer Marie Smith. (2013) Laboratory Blood Tests Useful in Monitoring Renal Function in Neonates. Neonatal Network 33:1, pages 35-40.
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Gian Maria Pacifici & Karel Allegaert. (2012) Clinical pharmacokinetics of vancomycin in the neonate: a review. Clinics 67:7, pages 831-837.
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Megan R. SutherlandBradley A. YoderDonald McCurnin, Steven Seidner, Lina GubhajuRonald I. Clyman & M. Jane Black. (2012) Effects of ibuprofen treatment on the developing preterm baboon kidney. American Journal of Physiology-Renal Physiology 302:10, pages F1286-F1292.
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Karel Allegaert, Jan De Hoon, Anne Debeer & Marc Gewillig. (2010) Renal Side Effects of Non-Steroidal Anti-Inflammatory Drugs in Neonates. Pharmaceuticals 3:2, pages 393-405.
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