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Research Article

Oxygen Glucose Deprivation Model of Cerebral Stroke in PC-12 Cells: Glucose as a Limiting Factor

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Pages 154-160 | Received 14 Sep 2007, Accepted 03 Feb 2008, Published online: 01 Feb 2009

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Qiong Mu, Hailong Zhou, Yingning Xu, Qian He, Xiao Luo, Wansong Zhang & Haibing Li. (2020) NPD1 inhibits excessive autophagy by targeting RNF146 and wnt/β-catenin pathway in cerebral ischemia-reperfusion injury. Journal of Receptors and Signal Transduction 40:5, pages 456-463.
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Articles from other publishers (19)

Ayesha Singh & Ruoli Chen. (2023) The Duration of Oxygen and Glucose Deprivation (OGD) Determines the Effects of Subsequent Reperfusion on Rat Pheochromocytoma (PC12) Cells and Primary Cortical Neurons. International Journal of Molecular Sciences 24:8, pages 7106.
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Sebastiano Antonio Rizzo, Oliver Bartley, Anne E. Rosser & Ben Newland. (2021) Oxygen-glucose deprivation in neurons: implications for cell transplantation therapies. Progress in Neurobiology 205, pages 102126.
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YoneJung Yoon, Georgios Voloudakis, Nathan Doran, Emily Zhang, Christina Dimovasili, Lei Chen, Zhiping Shao, Spyros Darmanis, Cheuk Tang, Jun Tang, Victoria X. Wang, Patrick R. Hof, Nikolaos K. Robakis & Anastasios Georgakopoulos. (2020) PS1 FAD mutants decrease ephrinB2-regulated angiogenic functions, ischemia-induced brain neovascularization and neuronal survival. Molecular Psychiatry 26:6, pages 1996-2012.
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Rita Matta, Yan Feng, Lauren H. Sansing & Anjelica L. Gonzalez. (2021) Endothelial cell secreted VEGF-C enhances NSC VEGFR3 expression and promotes NSC survival. Stem Cell Research 53, pages 102318.
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Alireza Pirsaraei Shabanzadeh, Philippe Matteo D’Onofrio, Mark Magharious, Kyung An Brian Choi, Philippe Patrick Monnier & Paulo Dieter Koeberle. (2019) Modifying PTEN recruitment promotes neuron survival, regeneration, and functional recovery after CNS injury. Cell Death & Disease 10:8.
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Peng Zhao, Ren-Yuan Chang, Ning Liu, Jing Wang, Ru Zhou, Xue Qi, Yue Liu, Lin Ma, Yang Niu, Tao Sun, Yu-Xiang Li, Yan-Ping He & Jian-Qiang Yu. (2017) Neuroprotective Effect of Oxysophocarpine by Modulation of MAPK Pathway in Rat Hippocampal Neurons Subject to Oxygen–Glucose Deprivation and Reperfusion. Cellular and Molecular Neurobiology 38:2, pages 529-540.
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Vito A. Baldassarro, Alessandra Marchesini, Fabrizio Facchinetti, Gino Villetti, Laura Calzà & Luciana Giardino. (2018) Cell death in pure-neuronal and neuron-astrocyte mixed primary culture subjected to oxygen-glucose deprivation: The contribution of poly(ADP-ribose) polymerases and caspases. Microchemical Journal 136, pages 215-222.
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Tao Tao, Jin-zhou Feng, Guang-hui Xu, Jie Fu, Xiao-gang Li & Xin-yue Qin. (2016) Minocycline Promotes Neurite Outgrowth of PC12 Cells Exposed to Oxygen-Glucose Deprivation and Reoxygenation Through Regulation of MLCP/MLC Signaling Pathways. Cellular and Molecular Neurobiology 37:3, pages 417-426.
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Satyendra K. Rajput, Arun K. Sharma, Chhuttan L. Meena, Aditya B. Pant, Rahul Jain & Shyam S. Sharma. (2016) Effect of L-pGlu-(1-benzyl)-l-His-l-Pro-NH2 against in-vitro and in-vivo models of cerebral ischemia and associated neurological disorders. Biomedicine & Pharmacotherapy 84, pages 1256-1265.
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Murali Vijayan & P. Hemachandra Reddy. (2016) Stroke, Vascular Dementia, and Alzheimer’s Disease: Molecular Links. Journal of Alzheimer's Disease 54:2, pages 427-443.
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Renyuan Chang, Ru Zhou, Xue Qi, Jing Wang, Fan Wu, Wenli Yang, Wannian Zhang, Tao Sun, Yuxiang Li & Jianqiang Yu. (2016) Protective effects of aloin on oxygen and glucose deprivation-induced injury in PC12 cells. Brain Research Bulletin 121, pages 75-83.
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Huizhen Guo, Songzhi Kong, Weimin Chen, Zhenhua Dai, Tongxiang Lin, Jiyan Su, Shanshan Li, Qingfeng Xie, Ziren Su, Yang Xu & Xiaoping Lai. (2014) Apigenin Mediated Protection of OGD-Evoked Neuron-Like Injury in Differentiated PC12 Cells. Neurochemical Research 39:11, pages 2197-2210.
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Bhakta Prasad Gaire & Hocheol Kim. (2014) Neuroprotective effects of Fructus Chebulae extracts on experimental models of cerebral ischemia. Journal of Traditional Chinese Medicine 34:1, pages 69-75.
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Bhakta Gaire, Nirmala Jamarkattel-Pandit, Donghun Lee, Jungbin Song, Ji Kim, Juyeon Park, Soyoung Jung, Ho-Young Choi & Hocheol Kim. (2013) Terminalia chebula Extract Protects OGD-R Induced PC12 Cell Death and Inhibits LPS Induced Microglia Activation. Molecules 18:3, pages 3529-3542.
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Megha Agrawal, Vivek Kumar, Abhishek K. Singh, Mahendra P. Kashyap, Vinay K. Khanna, Maqsood A. Siddiqui & Aditya B. Pant. (2012) trans -Resveratrol Protects Ischemic PC12 Cells by Inhibiting the Hypoxia Associated Transcription Factors and Increasing the Levels of Antioxidant Defense Enzymes . ACS Chemical Neuroscience 4:2, pages 285-294.
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Yu Tian, Chao Ma, Linyin Feng, Lei Zhang, Feiyue Hao, Li Pan & Maosheng Cheng. (2012) Synthesis and Biological Evaluation of (−)‐Linarinic Acid Derivatives as Neuroprotective Agents against OGD‐Induced Cell Damage. Archiv der Pharmazie 345:6, pages 423-430.
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Rui Zhang, Hong Zhang, Zhongxia Zhang, Tao Wang, Jingya Niu, Dongsheng Cui & Shunjiang Xu. (2012) Neuroprotective Effects of Pre-Treament with l-Carnitine and Acetyl-l-Carnitine on Ischemic Injury In Vivo and In Vitro. International Journal of Molecular Sciences 13:2, pages 2078-2090.
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Megha Agrawal, Vivek Kumar, Mahendra P. Kashyap, Vinay K. Khanna, Gursharn S. Randhawa & Aditya B. Pant. (2011) Ischemic insult induced apoptotic changes in PC12 cells: Protection by trans resveratrol. European Journal of Pharmacology 666:1-3, pages 5-11.
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Satyendra Kumar Rajput, Maqsood Ahmad Siddiqui, Vivek Kumar, Chhuttan Lal Meena, Aditya Bhushan Pant, Rahul Jain & Shyam Sunder Sharma. (2011) Protective effects of l-pGlu-(2-propyl)-l-His-l-ProNH2, a newer thyrotropin releasing hormone analog in in vitro and in vivo models of cerebral ischemia. Peptides 32:6, pages 1225-1231.
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