6,366
Views
88
CrossRef citations to date
0
Altmetric
Research Article

E-cigarette aerosols induce lower oxidative stress in vitro when compared to tobacco smoke

, , , , , & show all
Pages 465-476 | Received 15 Jul 2016, Accepted 05 Aug 2016, Published online: 30 Sep 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Riccardo Polosa, Renée O’Leary, Donald Tashkin, Rosalia Emma & Massimo Caruso. (2019) The effect of e-cigarette aerosol emissions on respiratory health: a narrative review. Expert Review of Respiratory Medicine 13:9, pages 899-915.
Read now
Guanghe Wang, Wenjing Liu & Weimin Song. (2019) Toxicity assessment of electronic cigarettes. Inhalation Toxicology 31:7, pages 259-273.
Read now
K. Monica Lee, Julia Hoeng, Sam Harbo, Ulrike Kogel, William Gardner, Michael Oldham, Eric Benson, Marja Talikka, Athanasios Kondylis, Florian Martin, Bjoern Titz, Sam Ansari, Keyur Trivedi, Emmanuel Guedj, Ashraf Elamin, Nikolai V. Ivanov, Patrick Vanscheeuwijck, Manuel C. Peitsch & Willie J. McKinney$suffix/text()$suffix/text(). (2018) Biological changes in C57BL/6 mice following 3 weeks of inhalation exposure to cigarette smoke or e-vapor aerosols. Inhalation Toxicology 30:13-14, pages 553-567.
Read now
Rakesh Dixit. (2016) Special issue on electronic cigarettes. Toxicology Mechanisms and Methods 26:6, pages 389-391.
Read now

Articles from other publishers (84)

Jane A. Foster. (2023) Consideration of vaping products as an alternative to adult smoking: a narrative review. Substance Abuse Treatment, Prevention, and Policy 18:1.
Crossref
Massimo Caruso, Rosalia Emma, Alfio Distefano, Sonja Rust, Konstantinos Poulas, Antonio Giordano, Vladislav Volarevic, Konstantinos Mesiakaris, Silvia Boffo, Aleksandar Arsenijevic, Georgios Karanasios, Roberta Pulvirenti, Aleksandar Ilic, Angelo Canciello, Pietro Zuccarello, Margherita Ferrante, Riccardo Polosa & Giovanni Li Volti. (2022) Comparative assessment of electronic nicotine delivery systems aerosol and cigarette smoke on endothelial cell migration: The Replica Project. Drug Testing and Analysis 15:10, pages 1164-1174.
Crossref
Patrudu Makena, Tatiana Kikalova, Gaddamanugu L. Prasad & Sarah A. Baxter. (2023) Oxidative Stress and Lung Fibrosis: Towards an Adverse Outcome Pathway. International Journal of Molecular Sciences 24:15, pages 12490.
Crossref
Lilan Wang, Yao Wang, Xuemin Yang, Kun Duan, Xingtao Jiang, Jianwen Chen, Peiqing Liu & Min Li. (2023) Cytotoxicity and cell injuries of flavored electronic cigarette aerosol and mainstream cigarette smoke: A comprehensive in vitro evaluation. Toxicology Letters 374, pages 96-110.
Crossref
Ghufran Saad Nsaif, Mahmood Al-Mualm & Anwer jaber faisal. (2023) The effect of e-cigarettes smoking on expression and methylation of CYP1A1 and CYP1B1 genes and other biochemical parameters. Materials Today: Proceedings 80, pages 3863-3866.
Crossref
Hongjuan Wang, Shulei Han, Huan Chen, Peizhen Li, Shigang Li, Yujuan Wu, Chunxia Zhang, Yaning Fu, Yushan Tian, Tong Liu, Hongwei Hou & Qingyuan Hu. (2022) In Vitro Toxicological Investigation and Risk Assessment of E-Cigarette Aerosols Based on a Novel Solvent-Free Extraction Method. ACS Omega 7:51, pages 48403-48415.
Crossref
Valérie Forest, Clément Mercier & Jérémie Pourchez. (2022) Considerations on dosimetry for in vitro assessment of e-cigarette toxicity. Respiratory Research 23:1.
Crossref
Bernardo Patella, Serena Di Vincenzo, Claudio Zanca, Luciano Bollaci, Maria Ferraro, Maria Rita Giuffrè, Chiara Cipollina, Maria Giuseppina Bruno, Giuseppe Aiello, Michele Russo, Rosalinda Inguanta & Elisabetta Pace. (2022) Electrochemical Quantification of H2O2 Released by Airway Cells Growing in Different Culture Media. Micromachines 13:10, pages 1762.
Crossref
Rosalia Emma, Massimo Caruso, Davide Campagna, Roberta Pulvirenti & Giovanni Li Volti. (2022) The Impact of Tobacco Cigarettes, Vaping Products and Tobacco Heating Products on Oxidative Stress. Antioxidants 11:9, pages 1829.
Crossref
Philip Baiden, Hannah S. Szlyk, Patricia Cavazos-Rehg, Henry K. Onyeaka, JaNiene E. Peoples & Erin Kasson. (2022) Use of electronic vaping products and mental health among adolescent high school students in the United States: The moderating effect of sex. Journal of Psychiatric Research 147, pages 24-33.
Crossref
Liam Simms, Fan Yu, Jessica Palmer, Kathryn Rudd, Edgar Trelles Sticken, Roman Wieczorek, Fiona Chapman, Lukasz Czekala, Matthew Stevenson & Grant O’Connell. (2022) Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Predict the Cardiotoxicity Potential of Next Generation Nicotine Products. Frontiers in Toxicology 4.
Crossref
Jingjie Zhang, Xiaoqing Chang, Tessa L. Holland, David E. Hines, Agnes L. Karmaus, Shannon Bell & K. Monica Lee. (2022) Evaluation of Inhalation Exposures and Potential Health Impacts of Ingredient Mixtures Using in vitro to in vivo Extrapolation. Frontiers in Toxicology 3.
Crossref
Oktay Aslaner. (2022) Comparison of Oxidative Effects of Electronic Cigarette and Tobacco Smoke Exposure Performed Experimentally. European Addiction Research 28:1, pages 41-47.
Crossref
Moon-shong Tang, Hyun-Wook Lee, Mao-wen Weng, Hsiang-Tsui Wang, Yu Hu, Lung-Chi Chen, Sung-Hyun Park, Huei-wei Chan, Jiheng Xu, Xue-Ru Wu, He Wang, Rui Yang, Karen Galdane, Kathryn Jackson, Annie Chu & Elizabeth Halzack. (2022) DNA damage, DNA repair and carcinogenicity: Tobacco smoke versus electronic cigarette aerosol. Mutation Research/Reviews in Mutation Research 789, pages 108409.
Crossref
Massimo Caruso, Rosalia Emma, Alfio Distefano, Sonja Rust, Konstantinos Poulas, Fahad Zadjali, Antonio Giordano, Vladislav Volarevic, Konstantinos Mesiakaris, Mohammed Al Tobi, Silvia Boffo, Aleksandar Arsenijevic, Pietro Zuccarello, Cesarina Giallongo, Margherita Ferrante, Riccardo Polosa, Giovanni Li Volti, Roberta Pulvirenti, Giuseppe Carota, Maria Rita Spampinato, Tancredi Caruso, Georgios Karanasios, Najwa Albalushi, Angelo Canciello & Aleksandar Ilic. (2021) Electronic nicotine delivery systems exhibit reduced bronchial epithelial cells toxicity compared to cigarette: the Replica Project. Scientific Reports 11:1.
Crossref
Dominic L. Palazzolo, Jordan Caudill, James Baron & Kevin Cooper. (2021) Fabrication and Validation of an Economical, Programmable, Dual-Channel, Electronic Cigarette Aerosol Generator. International Journal of Environmental Research and Public Health 18:24, pages 13190.
Crossref
Hoai Huong Thi Le, Chen-wei Liu, Philip DenaroIIIIII, Jordan Jousma, Ning-Yi Shao, Irfan Rahman & Won Hee Lee. (2021) Genome-wide differential expression profiling of lncRNAs and mRNAs in human induced pluripotent stem cell-derived endothelial cells exposed to e-cigarette extract. Stem Cell Research & Therapy 12:1.
Crossref
Jarosław Nuszkiewicz, Jolanta Czuczejko, Marta Maruszak, Marta Pawłowska, Alina Woźniak, Bogdan Małkowski & Karolina Szewczyk-Golec. (2021) Parameters of Oxidative Stress, Vitamin D, Osteopontin, and Melatonin in Patients with Lip, Oral Cavity, and Pharyngeal Cancer. Oxidative Medicine and Cellular Longevity 2021, pages 1-13.
Crossref
Mohammed Ali Selo, Johannes A. Sake, Kwang-Jin Kim & Carsten Ehrhardt. (2021) In vitro and ex vivo models in inhalation biopharmaceutical research — advances, challenges and future perspectives. Advanced Drug Delivery Reviews 177, pages 113862.
Crossref
Hannah E. O'Farrell, Reece Brown, Zac Brown, Branka Miljevic, Zoran D. Ristovski, Rayleen V. Bowman, Kwun M. Fong, Annalicia Vaughan & Ian A. Yang. (2021) E-cigarettes induce toxicity comparable to tobacco cigarettes in airway epithelium from patients with COPD. Toxicology in Vitro 75, pages 105204.
Crossref
Sindy Giebe, Anja Hofmann, Melanie Brux, Frazer Lowe, Damien Breheny, Henning Morawietz & Coy Brunssen. (2021) Comparative study of the effects of cigarette smoke versus next generation tobacco and nicotine product extracts on endothelial function. Redox Biology, pages 102150.
Crossref
Kyung-Taek Rim. (2021) Application of the adverse outcome pathway framework to predict the toxicity of chemicals in the semiconductor manufacturing industry. Molecular & Cellular Toxicology 17:3, pages 325-345.
Crossref
Tanya J. Bennet, Avineet Randhawa, Jessica Hua & Karen C. Cheung. (2021) Airway-On-A-Chip: Designs and Applications for Lung Repair and Disease. Cells 10:7, pages 1602.
Crossref
Lukasz Czekala, Fiona Chapman, Liam Simms, Kathryn Rudd, Edgar Trelles Sticken, Roman Wieczorek, Lisa Maria Bode, Jutta Pani, Nynke Moelijker, Remco Derr, Inger Brandsma, Giel Hendriks, Matthew Stevenson & Tanvir Walele. (2021) The in vitro ToxTracker and Aneugen Clastogen Evaluation extension assay as a tool in the assessment of relative genotoxic potential of e-liquids and their aerosols . Mutagenesis 36:2, pages 129-142.
Crossref
Oscar M. Camacho, James K. Ebajemito, Steven Coburn, Krishna Prasad, Sandra Costigan & James J. Murphy. (2021) Evidence From the Scientific Assessment of Electronic Cigarettes and Their Role in Tobacco Harm Reduction. Contributions to Tobacco & Nicotine Research 30:2, pages 63-108.
Crossref
Emmanuel Minet, Linsey E. Haswell, Sarah Corke, Anisha Banerjee, Andrew Baxter, Ivan Verrastro, Francisco De Abreu e Lima, Tomasz Jaunky, Simone Santopietro, Damien Breheny & Marianna D. Gaça. (2021) Application of text mining to develop AOP-based mucus hypersecretion genesets and confirmation with in vitro and clinical samples. Scientific Reports 11:1.
Crossref
Rachael E. Rayner, Patrudu Makena, G. L. Prasad & Estelle Cormet-Boyaka. (2021) Cigarette smoke preparations, not electronic nicotine delivery system preparations, induce features of lung disease in a 3D lung repeat-dose model. American Journal of Physiology-Lung Cellular and Molecular Physiology 320:2, pages L276-L287.
Crossref
N. East, E. Bishop, D. Breheny, M. Gaca & D. Thorne. (2021) A screening approach for the evaluation of tobacco-free ‘modern oral’ nicotine products using Real Time Cell Analysis. Toxicology Reports 8, pages 481-488.
Crossref
Jamie E. Spahn, Salomon A. Stavchansky & Zhengrong Cui. (2021) Critical research gaps in electronic cigarette devices and nicotine aerosols. International Journal of Pharmaceutics 593, pages 120144.
Crossref
Konstantinos Farsalinos. 2021. Toxicological Risk Assessment and Multi-System Health Impacts from Exposure. Toxicological Risk Assessment and Multi-System Health Impacts from Exposure 617 643 .
Daniel J. Smart & Gary Phillips. (2020) Collecting e‐cigarette aerosols for in vitro applications: A survey of the biomedical literature and opportunities to increase the value of submerged cell culture‐based assessments. Journal of Applied Toxicology 41:1, pages 161-174.
Crossref
Mark Taylor, Simone Santopietro, Andrew Baxter, Nicole East, Damien Breheny, David Thorne & Marianna Gaça. (2020) In vitro biological assessment of the stability of cigarette smoke aqueous aerosol extracts. BMC Research Notes 13:1.
Crossref
Christian Herr, Konstantinos Tsitouras, Julia Niederstraßer, Christina Backes, Christoph Beisswenger, Li Dong, Loïc Guillot, Andreas Keller & Robert Bals. (2020) Cigarette smoke and electronic cigarettes differentially activate bronchial epithelial cells. Respiratory Research 21:1.
Crossref
Alexandra Noël, Ekhtear Hossain, Zakia Perveen, Hasan Zaman & Arthur L. Penn. (2020) Sub-ohm vaping increases the levels of carbonyls, is cytotoxic, and alters gene expression in human bronchial epithelial cells exposed at the air–liquid interface. Respiratory Research 21:1.
Crossref
Stela Bozhilova, Andrew Baxter, Emma Bishop, Damien Breheny, David Thorne, Paul Hodges & Marianna Gaça. (2020) Optimization of aqueous aerosol extract (AqE) generation from e-cigarettes and tobacco heating products for in vitro cytotoxicity testing. Toxicology Letters 335, pages 51-63.
Crossref
Marta Szukalska, Krzysztof Szyfter, Ewa Florek, Juan P. Rodrigo, Alessandra Rinaldo, Antti A. Mäkitie, Primož Strojan, Robert P. Takes, Carlos Suárez, Nabil F. Saba, Boudewijn J.M. Braakhuis & Alfio Ferlito. (2020) Electronic Cigarettes and Head and Neck Cancer Risk—Current State of Art. Cancers 12:11, pages 3274.
Crossref
Bishop E, East N, Bozhilova S, Santopietro S, Smart D, Taylor M, Meredith S, Baxter A, Breheny D, Thorne D & Gaca M. (2020) An approach for the extract generation and toxicological assessment of tobacco-free ‘modern’ oral nicotine pouches. Food and Chemical Toxicology 145, pages 111713.
Crossref
Lauren C. Smith, Marsida Kallupi, Lani Tieu, Kokila Shankar, Abigail Jaquish, Jamie Barr, Yujuan Su, Nathan Velarde, Sharona Sedighim, Lieselot L. G. Carrette, Mike Klodnicki, Xin Sun, Giordano de Guglielmo & Olivier George. (2020) Validation of a nicotine vapor self-administration model in rats with relevance to electronic cigarette use. Neuropsychopharmacology 45:11, pages 1909-1919.
Crossref
Kalpana Baghel & Rashmi Srivastava. (2020) Effect of estrogen and stress on estrogen receptor 1 in the HPG axis of immature male Gallus gallus domesticus: Involvement of anti-oxidant system. Theriogenology 155, pages 98-113.
Crossref
Gregory L. Serpa, Nicholas D. Renton, Nari Lee, Meredith J. Crane & Amanda M. Jamieson. (2020) Electronic Nicotine Delivery System Aerosol-induced Cell Death and Dysfunction in Macrophages and Lung Epithelial Cells. American Journal of Respiratory Cell and Molecular Biology 63:3, pages 306-316.
Crossref
Shigeaki Ito, Kazushi Matsumura, Kanae Ishimori & Shinkichi Ishikawa. (2020) In vitro long‐term repeated exposure and exposure switching of a novel tobacco vapor product in a human organotypic culture of bronchial epithelial cells . Journal of Applied Toxicology 40:9, pages 1248-1258.
Crossref
Özge BEYAZÇİÇEK, Ersin BEYAZÇİÇEK, Recep ÖZMERDİVENLİ & Serif DEMİR. (2020) E-sigaralar: Yeni Bir Fenomen. Düzce Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi.
Crossref
F Karaaslan, A Dikilitaş & U Yiğit. (2020) The effects of vaping electronic cigarettes on periodontitis. Australian Dental Journal 65:2, pages 143-149.
Crossref
Isabella Dalle-Donne, Maria L. Garavaglia, Graziano Colombo, Emanuela Astori, Maria C. Lionetti, Caterina A.M. La Porta, Annalisa Santucci, Ranieri Rossi, Daniela Giustarini & Aldo Milzani. (2020) Cigarette smoke and glutathione: Focus on in vitro cell models. Toxicology in Vitro 65, pages 104818.
Crossref
I-Ling Chen, Ian Todd, Patrick J. Tighe & Lucy C. Fairclough. (2020) Electronic cigarette vapour moderately stimulates pro-inflammatory signalling pathways and interleukin-6 production by human monocyte-derived dendritic cells. Archives of Toxicology 94:6, pages 2097-2112.
Crossref
Jeffrey Ebersole, Vera Samburova, Yeongkwon Son, David Cappelli, Christina Demopoulos, Antonina Capurro, Andres Pinto, Brian Chrzan, Karl Kingsley, Katherine Howard, Nathaniel Clark & Andrey Khlystov. (2020) Harmful chemicals emitted from electronic cigarettes and potential deleterious effects in the oral cavity. Tobacco Induced Diseases 18:May.
Crossref
Farhana Hasan, Lavrent Khachatryan & Slawo Lomnicki. (2020) Comparative Studies of Environmentally Persistent Free Radicals on Total Particulate Matter Collected from Electronic and Tobacco Cigarettes. Environmental Science & Technology 54:9, pages 5710-5718.
Crossref
Justyna Szostak, Ee Tsin Wong, Bjoern Titz, Tom Lee, Sin Kei Wong, Tiffany Low, Kyeonghee Monica Lee, Jingjie Zhang, Ashutosh Kumar, Walter K. Schlage, Emmanuel Guedj, Blaine Phillips, Patrice Leroy, Ansgar Buettner, Yang Xiang, Florian Martin, Alain Sewer, Arkadiusz Kuczaj, Nikolai V. Ivanov, Karsta Luettich, Patrick Vanscheeuwijck, Manuel C. Peitsch & Julia Hoeng. (2020) A 6-month systems toxicology inhalation study in ApoE −/− mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke . American Journal of Physiology-Heart and Circulatory Physiology 318:3, pages H604-H631.
Crossref
Anna Merecz-Sadowska, Przemyslaw Sitarek, Hanna Zielinska-Blizniewska, Katarzyna Malinowska, Karolina Zajdel, Lukasz Zakonnik & Radoslaw Zajdel. (2020) A Summary of In Vitro and In Vivo Studies Evaluating the Impact of E-Cigarette Exposure on Living Organisms and the Environment. International Journal of Molecular Sciences 21:2, pages 652.
Crossref
D. Breheny, D. Thorne, A. Baxter, S. Bozhilova, T. Jaunky, S. Santopietro, M. Taylor, A. Terry & M. Gaça. (2020) The in vitro assessment of a novel vaping technology. Toxicology Reports 7, pages 1145-1156.
Crossref
Diego Marescotti, Carole Mathis, Vincenzo Belcastro, Patrice Leroy, Stefano Acali, Florian Martin, Rémi Dulize, David Bornand, Dariusz Peric, Emmanuel Guedj, Laura Ortega Torres, Matteo Biasioli, Matthieu Fuhrimann, Estela Fernandes, Felix Frauendorfer, Ignacio Gonzalez Suarez, Davide Sciuscio, Nikolai V. Ivanov, Manuel C. Peitsch & Julia Hoeng. (2020) Systems toxicology assessment of a representative e-liquid formulation using human primary bronchial epithelial cells. Toxicology Reports 7, pages 67-80.
Crossref
Shigeaki Ito, Mark Taylor, Sakura Mori, David Thorne, Tomoki Nishino, Damien Breheny, Marianna Gaça, Kei Yoshino & Christopher Proctor. (2019) An inter-laboratory in vitro assessment of cigarettes and next generation nicotine delivery products. Toxicology Letters 315, pages 14-22.
Crossref
Tobore Onojighofia Tobore. (2019) On the potential harmful effects of E‐Cigarettes (EC) on the developing brain: The relationship between vaping‐induced oxidative stress and adolescent/young adults social maladjustment.. Journal of Adolescence 76:1, pages 202-209.
Crossref
I‐Ling Chen, Ian Todd & Lucy C. Fairclough. (2019) Immunological and pathological effects of electronic cigarettes. Basic & Clinical Pharmacology & Toxicology 125:3, pages 237-252.
Crossref
Yeongkwon Son, Vladimir Mishin, Jeffrey D. Laskin, Gediminas Mainelis, Olivia A. Wackowski, Cristine Delnevo, Stephan Schwander, Andrey Khlystov, Vera Samburova & Qingyu Meng. (2019) Hydroxyl Radicals in E-Cigarette Vapor and E-Vapor Oxidative Potentials under Different Vaping Patterns. Chemical Research in Toxicology 32:6, pages 1087-1095.
Crossref
Huilin Shi, Xiaoming Fan, Austin Horton, Steven T. Haller, David J. Kennedy, Isaac T. Schiefer, Lance Dworkin, Christopher J. Cooper & Jiang Tian. (2019) The Effect of Electronic-Cigarette Vaping on Cardiac Function and Angiogenesis in Mice. Scientific Reports 9:1.
Crossref
Gozde Isik Andrikopoulos, Zoi Zagoriti, Stavros Topouzis & Konstantinos Poulas. (2019) Oxidative stress induced by electronic nicotine delivery systems (ENDS): Focus on respiratory system. Current Opinion in Toxicology 13, pages 81-89.
Crossref
Guy Jaccard, Donatien Tafin Djoko, Alexandra Korneliou, Regina Stabbert, Maxim Belushkin & Marco Esposito. (2019) Mainstream smoke constituents and in vitro toxicity comparative analysis of 3R4F and 1R6F reference cigarettes. Toxicology Reports 6, pages 222-231.
Crossref
Roberto Carnevale, Vittoria Cammisotto, Francesca Pagano & Cristina Nocella. 2018. Smoking Prevention and Cessation. Smoking Prevention and Cessation.
Satoru Munakata, Kanae Ishimori, Nobumasa Kitamura, Shinkichi Ishikawa, Yuichiro Takanami & Shigeaki Ito. (2018) Oxidative stress responses in human bronchial epithelial cells exposed to cigarette smoke and vapor from tobacco- and nicotine-containing products. Regulatory Toxicology and Pharmacology 99, pages 122-128.
Crossref
Kimberley R. Isett, Simone Rosenblum, Julie Ann Barna, Diana Hicks, Gregg H. Gilbert & Julia Melkers. (2018) Missed Opportunities for Detecting Alternative Nicotine Product Use in Youth: Data From the National Dental Practice–Based Research Network. Journal of Adolescent Health 63:5, pages 587-593.
Crossref
Humidah Alanazi, Hyun Jin Park, Jamila Chakir, Abdelhabib Semlali & Mahmoud Rouabhia. (2018) Comparative study of the effects of cigarette smoke and electronic cigarettes on human gingival fibroblast proliferation, migration and apoptosis. Food and Chemical Toxicology 118, pages 390-398.
Crossref
Rachel Z Behar, Yuhuan Wang & Prue Talbot. (2018) Comparing the cytotoxicity of electronic cigarette fluids, aerosols and solvents. Tobacco Control 27:3, pages 325-333.
Crossref
D. Thorne, M. Hollings, A. Seymour, J. Adamson, A. Dalrymple, M. Ballantyne & M. Gaca. (2018) Extreme testing of undiluted e-cigarette aerosol in vitro using an Ames air-agar-interface technique. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 828, pages 46-54.
Crossref
M. Flori Sassano, Eric S. Davis, James E. Keating, Bryan T. Zorn, Tavleen K. Kochar, Matthew C. Wolfgang, Gary L. Glish & Robert Tarran. (2018) Evaluation of e-liquid toxicity using an open-source high-throughput screening assay. PLOS Biology 16:3, pages e2003904.
Crossref
Tomasz Jaunky, Jason Adamson, Simone Santopietro, Anya Terry, David Thorne, Damien Breheny, Christopher Proctor & Marianna Gaça. (2018) Assessment of tobacco heating product THP1.0. Part 5: In vitro dosimetric and cytotoxic assessment. Regulatory Toxicology and Pharmacology 93, pages 52-61.
Crossref
Mark Taylor, David Thorne, Tony Carr, Damien Breheny, Paul Walker, Christopher Proctor & Marianna Gaça. (2018) Assessment of novel tobacco heating product THP1.0. Part 6: A comparative in vitro study using contemporary screening approaches. Regulatory Toxicology and Pharmacology 93, pages 62-70.
Crossref
Jason Adamson, Tomasz Jaunky, David Thorne & Marianna D. Gaça. (2018) Characterisation of the borgwaldt LM4E system for in vitro exposures to undiluted aerosols from next generation tobacco and nicotine products (NGPs). Food and Chemical Toxicology 113, pages 337-344.
Crossref
Jiayuan Zhao, Yipei Zhang, Jennifer D. Sisler, Justine Shaffer, Stephen S. Leonard, Anna M. Morris, Yong Qian, Dhimiter Bello & Philip Demokritou. (2018) Assessment of reactive oxygen species generated by electronic cigarettes using acellular and cellular approaches. Journal of Hazardous Materials 344, pages 549-557.
Crossref
Manuel C Peitsch, Riccardo Polosa, Christopher Proctor, Thord Hassler, Marianna Gaca, Erin Hill, Julia Hoeng & A Wallace Hayes. (2018) Next-generation tobacco and nicotine products. Toxicology Research and Application 2, pages 239784731877370.
Crossref
Konstantinos Farsalinos. (2017) Electronic cigarettes: an aid in smoking cessation, or a new health hazard?. Therapeutic Advances in Respiratory Disease 12, pages 175346581774496.
Crossref
Rebecca J. Przybyla, Jason Wright, Rajan Parthiban, Saeed Nazemidashtarjandi, Savas Kaya & Amir M. Farnoud. (2017) Electronic cigarette vapor alters the lateral structure but not tensiometric properties of calf lung surfactant. Respiratory Research 18:1.
Crossref
James Murphy, Marianna Gaca, Frazer Lowe, Emmanuel Minet, Damien Breheny, Krishna Prasad, Oscar Camacho, Ian M. Fearon, Chuan Liu, Christopher Wright, Kevin McAdam & Christopher Proctor. (2017) Assessing modified risk tobacco and nicotine products: Description of the scientific framework and assessment of a closed modular electronic cigarette. Regulatory Toxicology and Pharmacology 90, pages 342-357.
Crossref
Mark Taylor, Tomasz Jaunky, Katherine Hewitt, Damien Breheny, Frazer Lowe, Ian M. Fearon & Marianna Gaca. (2017) A comparative assessment of e-cigarette aerosols and cigarette smoke on in vitro endothelial cell migration. Toxicology Letters 277, pages 123-128.
Crossref
Tinne C.J. Mertens, Harry Karmouty-Quintana, Christian Taube & Pieter S. Hiemstra. (2017) Use of airway epithelial cell culture to unravel the pathogenesis and study treatment in obstructive airway diseases. Pulmonary Pharmacology & Therapeutics 45, pages 101-113.
Crossref
Damien Breheny, Jason Adamson, David Azzopardi, Andrew Baxter, Emma Bishop, Tony Carr, Ian Crooks, Katherine Hewitt, Tomasz Jaunky, Sophie Larard, Frazer Lowe, Oluwatobiloba Oke, Mark Taylor, Simone Santopietro, David Thorne, Benjamin Zainuddin, Marianna Gaça, Chuan Liu, James Murphy & Christopher Proctor. (2017) A novel hybrid tobacco product that delivers a tobacco flavour note with vapour aerosol (Part 2): In vitro biological assessment and comparison with different tobacco-heating products. Food and Chemical Toxicology 106, pages 533-546.
Crossref
Oluwatobiloba OkeDavid AzzopardiSarah CorkeKatherine HewittTony CarrNatalia CockcroftGeoff Foss-SmithMark TaylorFrazer Lowe. (2017) Assessment of Acute In Vitro Human Cellular Responses to Smoke Extracts from a Reduced Toxicant Prototype Cigarette . Applied In Vitro Toxicology 3:2, pages 182-192.
Crossref
Alyssa Zucchet & Grégory Schmaltz. (2017) Electronic cigarettes—A review of the physiological health effects. FACETS 2:1, pages 575-609.
Crossref
Damien Breheny, Oluwatobiloba Oke, Kamala Pant & Marianna Gaça. (2017) Comparative tumor promotion assessment of e-cigarette and cigarettes using the in vitro Bhas 42 cell transformation assay. Environmental and Molecular Mutagenesis 58:4, pages 190-198.
Crossref
Ignacio Gonzalez-SuarezDiego MarescottiFlorian MartinElena ScottiEmmanuel GuedjStefano AcaliRemi DulizeKarine BaumerDariusz PericStefan FrentzelNikolai V. IvanovJulia HoengManuel C. Peitsch. (2017) In Vitro Systems Toxicology Assessment of Nonflavored e-Cigarette Liquids in Primary Lung Epithelial Cells . Applied In Vitro Toxicology 3:1, pages 41-55.
Crossref
Wanda FieldsAnna MaioneBrian KeyserBetsy Bombick. (2017) Characterization and Application of the VITROCELL VC1 Smoke Exposure System and 3D EpiAirway Models for Toxicological and e-Cigarette Evaluations. Applied In Vitro Toxicology 3:1, pages 68-83.
Crossref
Karsta LuettichMarja TalikkaFrazer J. LoweLinsey E. HaswellJennifer ParkMarianna D. GacaJulia Hoeng. (2017) The Adverse Outcome Pathway for Oxidative Stress-Mediated EGFR Activation Leading to Decreased Lung Function. Applied In Vitro Toxicology 3:1, pages 99-109.
Crossref
Jason AdamsonXiang LiHuapeng CuiDavid ThorneFuwei XieMarianna D. Gaca. (2017) Nicotine Quantification In Vitro : A Consistent Dosimetry Marker for e-Cigarette Aerosol and Cigarette Smoke Generation . Applied In Vitro Toxicology 3:1, pages 14-27.
Crossref
David Thorne, Sophie Larard, Andrew Baxter, Clive Meredith & Marianna Gaҫa. (2017) The comparative in vitro assessment of e-cigarette and cigarette smoke aerosols using the γH2AX assay and applied dose measurements. Toxicology Letters 265, pages 170-178.
Crossref