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Toxicology Mechanisms and Methods Volume 16, 2006 - Issue 4
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Research Article

The Water Disinfectant Byproduct Dibromoacetonitrile Induces Apoptosis in Rat Intestinal Epithelial Cells: Possible Role of Redox Imbalance

Sam Jacob Department of Pathology, Molecular Toxicology, University of Texas Medical Branch, Galveston, Texas
,
Bhupendra S. Kaphalia Department of Pathology, Molecular Toxicology, University of Texas Medical Branch, Galveston, Texas
,
Nissi Jacob Department of Gastroenterology, Division of Endoscopy, University of Texas Medical Branch, Galveston, Texas
&
Ahmed E. Ahmed Department of Pathology, Molecular Toxicology, University of Texas Medical Branch, Galveston, Texas
Pages 227-234 | Received 31 Aug 2004, Accepted 05 Oct 2004, Published online: 09 Oct 2008

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Ching-Fong Liao, Shue-Fen Luo, Chin-Shaw Tsai, Tang-Yi Tsao, Shun-Liang Chen & Ming-Chung Jiang. (2008) CAS Enhances Chemotherapeutic Drug-Induced p53 Accumulation and Apoptosis: Use of CAS for High-Sensitivity Anticancer Drug Screening. Toxicology Mechanisms and Methods 18:9, pages 771-776.
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Articles from other publishers (9)

Peng Xue, Huihui Wang, Lili Yang, Zhiqiang Jiang, Hongliang Li, Qinxin Liu, Qiang Zhang, Melvin E. Andersen, M. James C. Crabbe, Lipeng Hao & Weidong Qu. (2022) NRF2-ARE signaling is responsive to haloacetonitrile-induced oxidative stress in human keratinocytes. Toxicology and Applied Pharmacology 450, pages 116163.
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Yukako Komaki, Koki Suganuma & Yuko Ibuki. (2022) Protective role of electrophile-reactive glutathione for DNA damage repair inhibitory effect of dibromoacetonitrile. Journal of Environmental Sciences 117, pages 305-314.
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Yukako Komaki & Yuko Ibuki. (2022) Inhibition of nucleotide excision repair and damage response signaling by dibromoacetonitrile: A novel genotoxicity mechanism of a water disinfection byproduct. Journal of Hazardous Materials 423, pages 127194.
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Yawen Chen, Ting Xu, Xinyue Yang, Wenhai Chu, Shuangqing Hu & Daqiang Yin. (2019) The toxic potentials and focus of disinfection byproducts based on the human embryonic kidney (HEK293) cell model. Science of The Total Environment 664, pages 948-957.
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Guanghua Lu, Donghong Qin, Yonghua Wang, Jianchao Liu & Wei Chen. (2018) Single and combined effects of selected haloacetonitriles in a human-derived hepatoma line. Ecotoxicology and Environmental Safety 163, pages 417-426.
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Thomas Caspari, James Dyer, Nathalie Fenner, Christian Dunn & Chris Freeman. (2017) The drinking water contaminant dibromoacetonitrile delays G1-S transition and suppresses Chk1 activation at broken replication forks. Scientific Reports 7:1.
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Paul A. White, George R. Douglas, David H. Phillips & Volker M. Arlt. (2017) Quantitative relationships between lacZ mutant frequency and DNA adduct frequency in Muta™Mouse tissues and cultured cells exposed to 3-nitrobenzanthrone . Mutagenesis, pages gew067.
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Naglaa Assaf, Neveen A. Salem, Wagdy K.B. Khalil & Hanaa H. Ahmed. (2011) Evaluation of the potential toxicity of dibromoacetonitrile-induced apoptosis and tumor-initiating activity in rat liver. Food and Chemical Toxicology 49:12, pages 3055-3062.
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John C. Lipscomb, Ebtehal El-Demerdash & Ahmed E. Ahmed. 2009. Reviews of Environmental Contamination and Toxicology Volume 198. Reviews of Environmental Contamination and Toxicology Volume 198 1 32 .

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