Induction of anaplastic lymphoma kinase (ALK) as a novel mechanism of EGFR inhibitor resistance in head and neck squamous cell carcinoma patient-derived models

Xiaoming OuyangDepartment of Dermatology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, Oregon;Department of Cell, Developmental & Cancer Biology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, Oregon

http://orcid.org/0000-0002-6632-3190

Ashley BarlingDepartment of Dermatology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, Oregon

Aletha LeschDepartment of Dermatology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, Oregon

Jeffrey W. TynerDepartment of Cell, Developmental & Cancer Biology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, Oregon;Division of Hematology and Medical Oncology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, Oregon;Knight Cancer Institute, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, Oregon

Gabrielle ChoonooDivision of Bioinformatics and Computational Biology, Department of Medical Informatics & Clinical Epidemiology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, Oregon

Christina ZhengDivision of Bioinformatics and Computational Biology, Department of Medical Informatics & Clinical Epidemiology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, Oregon

Sophia JengDivision of Bioinformatics and Computational Biology, Department of Medical Informatics & Clinical Epidemiology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, Oregon

Toni M. WestDepartment of Pharmacology, University of California at Davis, 451 Health Science Dr., Davis, California

Daniel ClayburghDepartment of Otolaryngology-Head and Neck Surgery, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, Oregon;Operative Care Division, Portland VA Health Care System, 3710 SW US Veterans Hospital Rd., Portland, Oregon

Sara A. CourtneidgeDepartment of Cell, Developmental & Cancer Biology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, Oregon;Knight Cancer Institute, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, Oregon

Shannon K. McWeeneyDivision of Bioinformatics and Computational Biology, Department of Medical Informatics & Clinical Epidemiology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, Oregon

Molly Kulesz-MartinDepartment of Dermatology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, Oregon;Department of Cell, Developmental & Cancer Biology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., Portland, OregonCorrespondence[email protected].

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Induction of anaplastic lymphoma kinase (ALK) as a novel mechanism of EGFR inhibitor resistance in head and neck squamous cell carcinoma patient-derived models

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Induction of anaplastic lymphoma kinase (ALK) as a novel mechanism of EGFR inhibitor resistance in head and neck squamous cell carcinoma patient-derived models

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