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Original

Similar Transcriptomic Alterations in Cx43 Knockdown and Knockout Astrocytes

, , , &
Pages 195-206 | Received 17 Oct 2007, Accepted 21 Dec 2007, Published online: 11 Jul 2009

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Milena B.P. Soares, Ricardo S. Lima, Bruno S.F. Souza, Juliana F. Vasconcelos, Leonardo L. Rocha, Ricardo Ribeiro dos Santos, Sanda Iacobas, Regina C. Goldenberg, Michael P. Lisanti, Dumitru A. Iacobas, Herbert B. Tanowitz, David C. Spray & Antonio C. Campos de Carvalho. (2011) Reversion of gene expression alterations in hearts of mice with chronic chagasic cardiomyopathy after transplantation of bone marrow cells. Cell Cycle 10:9, pages 1448-1455.
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Dumitru Andrei Iacobas & Lei Xi. (2022) Theory and Applications of the (Cardio) Genomic Fabric Approach to Post-Ischemic and Hypoxia-Induced Heart Failure. Journal of Personalized Medicine 12:8, pages 1246.
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David Mazaud, Anna Capano & Nathalie Rouach. (2021) The many ways astroglial connexins regulate neurotransmission and behavior. Glia 69:11, pages 2527-2545.
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Dumitru Iacobas, Jing Wen, Sanda Iacobas, Noa Schwartz & Chaim Putterman. (2021) Remodeling of Neurotransmission, Chemokine, and PI3K-AKT Signaling Genomic Fabrics in Neuropsychiatric Systemic Lupus Erythematosus. Genes 12:2, pages 251.
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Dumitru Andrei Iacobas. (2020) Powerful quantifiers for cancer transcriptomics. World Journal of Clinical Oncology 11:9, pages 679-704.
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Dumitru A. Iacobas. (2020) Biomarkers, Master Regulators and Genomic Fabric Remodeling in a Case of Papillary Thyroid Carcinoma. Genes 11:9, pages 1030.
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Lindice M. Nisimura, Laura L. Coelho, Tatiana G. de Melo, Paloma de Carvalho Vieira, Pedro H. Victorino, Luciana R. Garzoni, David C. Spray, Dumitru A. Iacobas, Sanda Iacobas, Herbert B. Tanowitz & Daniel Adesse. (2020) Trypanosoma cruzi Promotes Transcriptomic Remodeling of the JAK/STAT Signaling and Cell Cycle Pathways in Myoblasts. Frontiers in Cellular and Infection Microbiology 10.
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Dumitru A Iacobas, Sanda Iacobas, Randy F Stout & David C Spray. (2020) Cellular Environment Remodels the Genomic Fabrics of Functional Pathways in Astrocytes. Genes 11:5, pages 520.
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Maria Consiglia Trotta, Rosa Maisto, Francesca Guida, Serena Boccella, Livio Luongo, Cornel Balta, Giovanbattista D’Amico, Hildegard Herman, Anca Hermenean, Claudio Bucolo & Michele D’Amico. (2019) The activation of retinal HCA2 receptors by systemic beta-hydroxybutyrate inhibits diabetic retinal damage through reduction of endoplasmic reticulum stress and the NLRP3 inflammasome. PLOS ONE 14:1, pages e0211005.
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Elizabeth J. Millings, Maria Caterina De Rosa, Sarah Fleet, Kazuhisa Watanabe, Richard Rausch, Dieter Egli, Gen Li, Charles A. Leduc, Yiying Zhang, Stuart G. Fischer & Rudolph L. Leibel. (2018) ILDR2 has a negligible role in hepatic steatosis. PLOS ONE 13:5, pages e0197548.
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Gerald A. Dienel. (2017) Lack of appropriate stoichiometry: Strong evidence against an energetically important astrocyte-neuron lactate shuttle in brain. Journal of Neuroscience Research 95:11, pages 2103-2125.
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Brian Skriver Nielsen, Daniel Bloch Hansen, Bruce R. Ransom, Morten Schak Nielsen & Nanna MacAulay. (2017) Connexin Hemichannels in Astrocytes: An Assessment of Controversies Regarding Their Functional Characteristics. Neurochemical Research 42:9, pages 2537-2550.
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Chunshan Zhao, Jinnv Fang, Chunguo Li & Min Zhang. (2017) Connexin43 and AMPK Have Essential Role in Resistance to Oxidative Stress Induced Necrosis. BioMed Research International 2017, pages 1-7.
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Dumitru Andrei Iacobas. (2016) The Genomic Fabric Perspective on the Transcriptome Between Universal Quantifiers and Personalized Genomic Medicine. Biological Theory 11:3, pages 123-137.
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Gerald A. Dienel & Nancy F. Cruz. (2015) Biochemical, Metabolic, and Behavioral Characteristics of Immature Chronic Hyperphenylalanemic Rats. Neurochemical Research 41:1-2, pages 16-32.
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J. Velíšková, D. Iacobas, S. Iacobas, G. Sidyelyeva, T. Chachua & L. Velíšek. (2015) Oestradiol Regulates Neuropeptide Y Release and Gene Coupling with the GABAergic and Glutamatergic Synapses in the Adult Female Rat Dentate Gyrus. Journal of Neuroendocrinology 27:12, pages 911-920.
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L. K. Friedman, J. Mancuso, A. Patel, V. Kudur, J. R. Leheste, S. Iacobas, J. Botta, D. A. Iacobas & D. C. Spray. (2013) Transcriptome profiling of hippocampal CA1 after early-life seizure-induced preconditioning may elucidate new genetic therapies for epilepsy. European Journal of Neuroscience 38:1, pages 2139-2152.
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Nancy F. Cruz, Kelly K. Ball, Stanley C. Froehner, Marvin E. Adams & Gerald A. Dienel. (2013) Regional registration of [6‐ 14 C]glucose metabolism during brain activation of α‐syntrophin knockout mice . Journal of Neurochemistry 125:2, pages 247-259.
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S. Iacobas, D.A. Iacobas, D.C. Spray & E. Scemes. (2012) The connexin43-dependent transcriptome during brain development: Importance of genetic background. Brain Research 1487, pages 131-139.
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Eduardo R. Lazarowski. (2012) Vesicular and conductive mechanisms of nucleotide release. Purinergic Signalling 8:3, pages 359-373.
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Sylvia O. Suadicani, Rodolfo Iglesias, Junjie Wang, Gerhard Dahl, David C. Spray & Eliana Scemes. (2012) ATP signaling is deficient in cultured pannexin1‐null mouse astrocytes. Glia 60:7, pages 1106-1116.
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Sanda Iacobas & Dumitru A. Iacobas. (2011) Astrocyte proximity modulates the myelination gene fabric of oligodendrocytes. Neuron Glia Biology 6:3, pages 157-169.
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Marcelo F. Santiago, Pepe Alcami, Katharine M. Striedinger, David C. Spray & Eliana Scemes. (2010) The Carboxyl-terminal Domain of Connexin43 Is a Negative Modulator of Neuronal Differentiation. Journal of Biological Chemistry 285:16, pages 11836-11845.
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Xiuxin Liu, Kazue Hashimoto-Torii, Masaaki Torii, Chen Ding & Pasko Rakic. (2010) Gap Junctions/Hemichannels Modulate Interkinetic Nuclear Migration in the Forebrain Precursors. The Journal of Neuroscience 30:12, pages 4197-4209.
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D. A. Iacobas, S. Iacobas, N. Thomas & D. C. Spray. (2009) Sex-dependent gene regulatory networks of the heart rhythm. Functional & Integrative Genomics 10:1, pages 73-86.
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Cima Cina, Karen Maass, Martin Theis, Klaus Willecke, John F. Bechberger & Christian C. Naus. (2009) Involvement of the Cytoplasmic C-Terminal Domain of Connexin43 in Neuronal Migration. The Journal of Neuroscience 29:7, pages 2009-2021.
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Dumitru A. Iacobas, Chenhao Fan, Sanda Iacobas & Gabriel G. Haddad. (2008) Integrated transcriptomic response to cardiac chronic hypoxia: translation regulators and response to stress in cell survival. Functional & Integrative Genomics 8:3, pages 265-275.
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