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Journal of Immunotoxicology Volume 1, 2004 - Issue 1
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Research Article

Suppression of Immune Function and Susceptibility to Infections in Humans: Association of Immune Function with Clinical Disease

Robert W. Luebke Immunotoxicology Branch, Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA
,
Christine Parks Epidemiology Branch, Environmental Diseases & Medicine Program, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, USA
&
Michael I. Luster Toxicology & Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia, USA
Pages 15-24 | Published online: 29 Sep 2008

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Daniel Willis, Mary Popovech, Francesca Gany & Judith Zelikoff. (2012) Toxicology of Smokeless Tobacco: Implications for Immune, Reproductive, and Cardiovascular Systems. Journal of Toxicology and Environmental Health, Part B 15:5, pages 317-331.
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MichaelC. R. Alavanja, MaryH. Ward & Peggy Reynolds. (2007) Carcinogenicity of Agricultural Pesticides in Adults and Children. Journal of Agromedicine 12:1, pages 39-56.
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Pietro D'Addabbo, Domenico Frezza & Courtney E.W. Sulentic. (2023) Evolutive emergence and divergence of an Ig regulatory node: An environmental sensor getting cues from the aryl hydrocarbon receptor?. Frontiers in Immunology 14.
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Lori Crawford, Scott A. Halperin, Michael W. Dzierlenga, Becky Skidmore, Matthew W. Linakis, Shinichi Nakagawa & Matthew P. Longnecker. (2023) Systematic review and meta-analysis of epidemiologic data on vaccine response in relation to exposure to five principal perfluoroalkyl substances. Environment International 172, pages 107734.
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Jamie C. DeWitt, Sarah J. Blossom & Laurel A. Schaider. (2018) Exposure to per-fluoroalkyl and polyfluoroalkyl substances leads to immunotoxicity: epidemiological and toxicological evidence. Journal of Exposure Science & Environmental Epidemiology 29:2, pages 148-156.
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Martina Tunegová, Eva Samková, Lucie Hasoňová, Marcela Klimešová, Aneta Marková, Robert Kala & Róbert Toman. (2018) Occurrence of chemical contaminants in animal products during 1999–2016 in the Czech Republic. British Food Journal 120:9, pages 2142-2154.
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J.C. DeWitt & R.W. Luebke. 2018. Comprehensive Toxicology. Comprehensive Toxicology 272 281 .
Dori Germolec, Robert Luebke, Andrew Rooney, Kelly Shipkowski, Rob Vandebriel & Henk van Loveren. (2017) Immunotoxicology: A brief history, current status and strategies for future immunotoxicity assessment. Current Opinion in Toxicology 5, pages 55-59.
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Ying Mu, Dianne E Godar & Stephen J Merrill. (2017) A perspective on the challenges and issues in developing biomarkers for human allergic risk assessments. Biomarkers in Medicine 11:7, pages 523-526.
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Christine G. Parks, Jane A. Hoppin, Anneclaire J. De Roos, Karen H. Costenbader, Michael C. Alavanja & Dale P. Sandler. (2016) Rheumatoid Arthritis in Agricultural Health Study Spouses: Associations with Pesticides and Other Farm Exposures. Environmental Health Perspectives 124:11, pages 1728-1734.
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Martine Vrijheid, Maribel Casas, Mireia Gascon, Damaskini Valvi & Mark Nieuwenhuijsen. (2016) Environmental pollutants and child health—A review of recent concerns. International Journal of Hygiene and Environmental Health 219:4-5, pages 331-342.
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Angela L. Rasmussen & Michael G. Katze. (2016) Genomic Signatures of Emerging Viruses: A New Era of Systems Epidemiology. Cell Host & Microbe 19:5, pages 611-618.
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Jamie C. DeWitt, Dori R. Germolec, Robert W. Luebke & Victor J. Johnson. (2016) Associating Changes in the Immune System with Clinical Diseases for Interpretation in Risk Assessment. Current Protocols in Toxicology 67:1.
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Robert W. Luebke. 2015. Mammalian Toxicology. Mammalian Toxicology 323 339 .
J.C. DeWitt & R.W. Luebke. 2015. Reference Module in Biomedical Sciences. Reference Module in Biomedical Sciences.
April Neal-Kluever, Jason Aungst, Yan Gu, Karen Hatwell, Kristi Muldoon-Jacobs, Ayesha Liem, Adejoke Ogungbesan & Mary Shackelford. (2014) Infant toxicology: State of the science and considerations in evaluation of safety. Food and Chemical Toxicology 70, pages 68-83.
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Florence G. Burleson & Stefanie C.M. Burleson. 2014. The Role of the Study Director in Nonclinical Studies. The Role of the Study Director in Nonclinical Studies 393 404 .
Yaseen Abdelrahman, Mohammad Fararjeh, Wesam Abdel-Razeq, Mohammad K Mohammad & Yasser Bustanji. (2014) Assessment of possible immunotoxicity of the antipsychotic drug clozapine. Journal of Pharmacy and Pharmacology 66:3, pages 378-386.
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Barthelemy Tandu-Umba, Donatien K. Dedetemo & Gilbert L. Mananga. (2014) Maternal Stress and Pregnancy Outcomes. Open Journal of Obstetrics and Gynecology 04:07, pages 361-370.
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J. Rocourt. 2014. Encyclopedia of Food Safety. Encyclopedia of Food Safety 89 97 .
J. Rocourt. 2014. Encyclopedia of Food Safety. Encyclopedia of Food Safety 323 331 .
Stephen M. Bauer, Anirban Roy, Jason Emo, Timothy J. Chapman, Steve N. Georas & B. Paige Lawrence. (2012) The Effects of Maternal Exposure to Bisphenol A on Allergic Lung Inflammation into Adulthood. Toxicological Sciences 130:1, pages 82-93.
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Robert W. Luebke, Jamie C. Dewitt, Dori R. Germolec, Keith D. Salazar & Nancy I. Kerkvliet. 2012. Dioxins and Health. Dioxins and Health 171 192 .
Susana Mohr & Ijoni Hilda Costabeber. (2012) Aspectos toxicológicos e ocorrência dos bifenilos policlorados em alimentos. Ciência Rural 42:3, pages 559-566.
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Andrew A. Rooney, Robert W. Luebke, MaryJane K. Selgrade & Dori R. Germolec. 2012. Molecular, Clinical and Environmental Toxicology. Molecular, Clinical and Environmental Toxicology 251 287 .
Carsten Heilmann. 2012. Immunotoxicity, Immune Dysfunction, and Chronic Disease. Immunotoxicity, Immune Dysfunction, and Chronic Disease 389 398 .
M.C. Ferrante, G. Mattace Raso, E. Esposito, G. Bianco, A. Iacono, M.T. Clausi, P. Amero, A. Santoro, R. Simeoli, G. Autore & R. Meli. (2011) Effects of non-dioxin-like polychlorinated biphenyl congeners (PCB 101, PCB 153 and PCB 180) alone or mixed on J774A.1 macrophage cell line: modification of apoptotic pathway. Toxicology Letters 202:1, pages 61-68.
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Christine G. Parks, Brian T. Walitt, Mary Pettinger, Jiu‐Chiuan Chen, Anneclaire J. de Roos, Julie Hunt, Gloria Sarto & Barbara V. Howard. (2011) Insecticide use and risk of rheumatoid arthritis and systemic lupus erythematosus in the Women's Health Initiative Observational Study. Arthritis Care & Research 63:2, pages 184-194.
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Robert V. House & Mary J. Selgrade. (2010) A Quarter-Century of Immunotoxicology: Looking Back, Looking Forward. Toxicological Sciences 118:1, pages 1-3.
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Rodney R. Dietert. 2010. Biomarkers. Biomarkers 307 322 .
Ronald N. Hines, Dana Sargent, Herman Autrup, Linda S. Birnbaum, Robert L. Brent, Nancy G. Doerrer, Elaine A. Cohen Hubal, Daland R. Juberg, Christian Laurent, Robert Luebke, Klaus Olejniczak, Christopher J. Portier & William Slikker. (2010) Approaches for Assessing Risks to Sensitive Populations: Lessons Learned from Evaluating Risks in the Pediatric Population. Toxicological Sciences 113:1, pages 4-26.
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J.C. DeWitt & R.W. Luebke. 2010. Comprehensive Toxicology. Comprehensive Toxicology 455 465 .
Robert W. Luebke. 2010. Immunotoxicity Testing. Immunotoxicity Testing 119 141 .
Håvard Jenssen. (2009) Therapeutic Approaches Using Host Defence Peptides to Tackle Herpes Virus Infections. Viruses 1:3, pages 939-964.
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Robert W. Luebke, Celine A. Beamer, Christal Bowman, Jamie DeWitt, Kymberly Gowdy, Victor J. Johnson, David M. Shepherd & Dori M. Germolec. 2009. General, Applied and Systems Toxicology. General, Applied and Systems Toxicology.
Ian Gourley & Jacques Descotes. 2008. Immunotoxicology Strategies for Pharmaceutical Safety Assessment. Immunotoxicology Strategies for Pharmaceutical Safety Assessment 373 384 .
MaryJane K. Selgrade. (2007) Immunotoxicity—The Risk is Real. Toxicological Sciences 100:2, pages 328-332.
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Dori Germolec, Robert Luebke, Robert House & Gary Rosenthal. 2006. Toxicological Testing Handbook. Toxicological Testing Handbook 391 415 .
MaryJane K. Selgrade. (2005) Biomarkers of effects: The immune system. Journal of Biochemical and Molecular Toxicology 19:3, pages 177-179.
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