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Clinical Toxicology Volume 55, 2017 - Issue 7
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Short Communication

Loperamide metabolite-induced cardiomyopathy and QTc prolongation

Zabeer BhattiDepartment of Medicine, State University of New York, Syracuse, NY, USACorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-7161-4750
ORCID Icon,
Jessica NorsworthyDepartment of Medicine, State University of New York, Syracuse, NY, USA
&
Tamas SzombathyDepartment of Medicine, State University of New York, Syracuse, NY, USA
Pages 659-661 | Received 31 Jan 2017, Accepted 28 Feb 2017, Published online: 28 Mar 2017

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Vincent R. Lee, Ariel Vera, Andreia Alexander, Bruce Ruck, Lewis S. Nelson, Paul Wax, Sharan Campleman, Jeffrey Brent & Diane P. Calello. (2019) Loperamide misuse to avoid opioid withdrawal and to achieve a euphoric effect: high doses and high risk. Clinical Toxicology 57:3, pages 175-180.
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William Eggleston, Jeanna M. Marraffa & Nicholas Nacca. (2017) In response to: “Loperamide metabolite-induced cardiomyopathy and QTc prolongation”. Clinical Toxicology 55:9, pages 1023-1023.
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Articles from other publishers (10)

. 2022. Arzneimitteltherapie in der Palliativmedizin. Arzneimitteltherapie in der Palliativmedizin 109 180 .
Todd Teigeler, Heather Stahura, Rizwan Alimohammad, Gautham Kalahasty, Jayanthi N. Koneru, Michael Ellenbogen, Kenneth A. Ellenbogen & Santosh K. Padala. (2019) Electrocardiographic changes in loperamide toxicity: Case report and review of literature. Journal of Cardiovascular Electrophysiology 30:11, pages 2618-2626.
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Qian-meng Lin, Ni-hong Pang, Ying-hui Li, Huan-le Huang, Xiao-dan Zhang, Guo-xin Hu & Zeng-shou Wang. (2019) Investigation of the effects of axitinib on the pharmacokinetics of loperamide and its main metabolite N-demethylated loperamide in rats by UPLC-MS/MS. Chemico-Biological Interactions 310, pages 108744.
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Kasha Bornstein, Timothy Montrief & Mehruba Anwar Parris. (2019) Left Ventricular Regional Wall Motion Abnormality in the Setting of Acute Loperamide Overdose. Clinical Practice and Cases in Emergency Medicine 3:3, pages 262-266.
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Lee A. Wolfrum, Aimee S. Nordmeyer, Christopher W. Racine & Stephanie D. Nichols. (2019) Loperamide-Associated Opioid Use Disorder and Proposal of an Alternative Treatment with Buprenorphine. Journal of Addiction Medicine 13:3, pages 245-247.
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Fabrizio Schifano, Stefania Chiappini, John Corkery & Amira Guirguis. (2018) Abuse of Prescription Drugs in the Context of Novel Psychoactive Substances (NPS): A Systematic Review. Brain Sciences 8:4, pages 73.
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Tamer Akel & Soad Bekheit. (2018) Loperamide cardiotoxicity: “A Brief Review”. Annals of Noninvasive Electrocardiology 23:2, pages e12505.
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Hannah R. Fudin, Jennifer L. Babin, Lisa T. Hong, Jennifer Ku, Alisyn L. May, Alexander Wisner, F. Scott Hall & Sidhartha D. Ray. 2018. A Worldwide Yearly Survey of New Data in Adverse Drug Reactions. A Worldwide Yearly Survey of New Data in Adverse Drug Reactions 29 89 .
Peter E. Wu & David N. Juurlink. (2017) Clinical Review: Loperamide Toxicity. Annals of Emergency Medicine 70:2, pages 245-252.
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. (2017) Loperamide overdose. Reactions Weekly 1647:1, pages 187-187.
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