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Clinical Toxicology Volume 46, 2008 - Issue 1
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Case Report

Recurrent life-threatening ventricular dysrhythmias associated with acute hydrofluoric acid ingestion: Observations in one case and implications for mechanism of toxicity

Rais Vohra University of Texas, Southwestern Medical Center at Dallas, Dallas, Texas, USA
, M.D.,
Larissa I. Velez University of Texas, Southwestern Medical Center at Dallas, Dallas, Texas, USA
, M.D.,
Wilfredo Rivera University of Texas, Southwestern Medical Center at Dallas, Dallas, Texas, USA
, M.D.,
Fernando L. Benitez University of Texas, Southwestern Medical Center at Dallas, Dallas, Texas, USA
, M.D. &
Kathleen A. Delaney University of Texas, Southwestern Medical Center at Dallas, Dallas, Texas, USA
, M.D.
Pages 79-84 | Received 25 Jul 2005, Accepted 09 Jun 2006, Published online: 20 Jan 2009

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Ming-Ling Wu, Juo-Fang Deng & Ju-Sing Fan. (2010) Survival after hypocalcemia, hypomagnesemia, hypokalemia and cardiac arrest following mild hydrofluoric acid burn. Clinical Toxicology 48:9, pages 953-955.
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Articles from other publishers (27)

Bryant A. Menke, Christine Ryu, Grant A. Justin, Rao V. Chundury, Brent R. Hayek, Matthew R. Debiec & Steven Yeh. (2023) Ophthalmic manifestations and management considerations for emerging chemical threats. Frontiers in Toxicology 5.
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Zachary Illg, Joseph Carpenter, Tim P. Moran, Emily Kiernan & Brian Patrick Murray. (2023) Hydrofluoric acid ingestions: Retrospective evaluations from cases reported to the National Poison Data System 2007–2017. Journal of the American College of Emergency Physicians Open 4:5.
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Myeong-sik Kim, Heejun Shin, Hanbit Kim, Sung-Woo Choi, Ji Eun Kim, Han You Lee & Ji Eun Moon. (2023) Analysis of Factors Contributing to the Occurrence of Systemic Toxicity in Patients with Hydrofluoric Acid Skin Exposure Injury: An Individual Participant Data Meta-Analysis of 125 Clinical Cases from 1979 to 2020. Journal of Burn Care & Research 44:2, pages 335-346.
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Hsuan-Yun Hu, Shyh-Yuh Wei, Szu-Yu Lin, Li-Hsuan Chen & Chih-Hsin Pan. (2022) “Breaking heart” due to hydrofluoric acid burns in a case of homicide. Forensic Science International 341, pages 111468.
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Emine Pınar Küllüoğlu, Doğa Lüleyap, Alper Çiçek, Ayşe Berna Anıl, Çapan Konca, Emel Berksoy, Gamze Gökalp, Ayşenur Özel Doğruöz & Demet Alaygut. (2022) A Case of Severe Poisoning due to Oral Hydrofluoric Acid Ingestion that Could Survive with Timely Effective Treatments. Journal of Dr Behcet Uz Children s Hospital 12:3, pages 233-238.
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Tian Zhao, Hexin Zhu, Ming Dong, Minmin Zou, Songfan Tang, Mingliang Luo & Xianggang Li. (2022) Low-Temperature and Additive-Free Synthesis of Spherical MIL-101(Cr) with Enhanced Dye Adsorption Performance. Inorganics 10:3, pages 33.
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Marco Antonio Garnica Escamilla, Martín de Jesús Sánchez Zúñiga, Elvira Alejandra Támez Coyotzin, Jocelin Reyes Reyes, Damaris Abigail García López, Anahali Gonzalez Diaz, Martín Jair González Mañon & Julio Oscar Peñaloza Hernández. (2022) Quemadura química por ácido fluorhídrico: mecanismos fisiopatológicos de la lesión. Medicina Crítica 36:6, pages 371-377.
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Lakshmikanthan Panneerselvam, Azhwar Raghunath, Kiruthika Sundarraj & Ekambaram Perumal. (2019) Acute fluoride exposure alters myocardial redox and inflammatory markers in rats. Molecular Biology Reports 46:6, pages 6155-6164.
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Gamze Ozsoy, Tanil Kendirli, Ufuk Ates, Oktay Perk, Ebru Azapagasi, Serhan Ozcan, Cagdas Baran, Aytac Goktug & Huseyin Dindar. (2019) Fatal Refractory Ventricular Fibrillation Due to Ingestion of Hydrofluoric Acid. Pediatric Emergency Care 35:11, pages e201-e202.
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Jianfen Zhang, Liangfang Ni, Xinhua Jiang, Zuliang Hu, Chunmao Han, Bin Xu, Yuanhai Zhang & Xingang Wang. (2018) Clinical significance of urinary fluoride levels in patients with hydrofluoric acid burns. Burns 44:8, pages 2074-2079.
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Ali Sait Kavakli & Nilgun Kavrut Ozturk. (2018) Recurrent ventricular fibrillation associated with acute ingestion of hydrofluoric acid. Journal of Clinical Anesthesia 46, pages 8-9.
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Yuanhai Zhang, Xingang Wang, Yuezhen Liu, Xinhua Jiang, Chunjiang Ye, Liangfang Ni, Liping Zhang, Jianfen Zhang, Bin Xu & Chunmao Han. (2017) Management of a Rare Case With Severe Hydrofluoric Acid Burns: Important Roles of Neutralizers and Continuous Renal Replacement Therapy. The International Journal of Lower Extremity Wounds 16:4, pages 289-295.
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Qinhua Pu, Jinxian Qian, Weiyi Tao, Aixiang Yang, Jian Wu & Yaodong Wang. (2017) Extracorporeal membrane oxygenation combined with continuous renal replacement therapy in cutaneous burn and inhalation injury caused by hydrofluoric acid and nitric acid. Medicine 96:48, pages e8972.
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Lakshmikanthan Panneerselvam, Azhwar Raghunath & Ekambaram Perumal. (2017) Differential expression of myocardial heat shock proteins in rats acutely exposed to fluoride. Cell Stress and Chaperones 22:5, pages 743-750.
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Lakshmikanthan Panneerselvam, Azhwar Raghunath & Ekambaram Perumal. (2017) Acute fluoride poisoning alters myocardial cytoskeletal and AMPK signaling proteins in rats. International Journal of Cardiology 229, pages 96-101.
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Joseph K. Maddry, Avery Kester & Kennon Heard. (2017) Prolonged hypocalcemia refractory to calcium gluconate after ammonium bifluoride ingestion in a pediatric patient. The American Journal of Emergency Medicine 35:2, pages 378.e1-378.e2.
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. (2016) How Do I Diagnose and Treat Workers With Injuries From Hydrofluoric Acid?. Journal of Occupational & Environmental Medicine 58:7, pages e275-e277.
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Yuanhai Zhang, Chunmao Han, Xuguang Qiu, Liangfang Ni, Xinxing Mao & Xingang Wang. (2016) Response to “Chemical injuries caused by the hydrofluoric acid leak”. Burns 42:3, pages 706-708.
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Lakshmikanthan Panneerselvam, Vimal Govindarajan, Jaishabanu Ameeramja, Harikumaran Raveendran Nair & Ekambaram Perumal. (2015) Single oral acute fluoride exposure causes changes in cardiac expression of oxidant and antioxidant enzymes, apoptotic and necrotic markers in male rats. Biochimie 119, pages 27-35.
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Carolyn K. Reeb-Whitaker, Carly M. Eckert, Naomi J. Anderson & David K. Bonauto. (2015) Occupational Hydrofluoric Acid Injury from Car and Truck Washing — Washington State, 2001–2013. MMWR. Morbidity and Mortality Weekly Report 64:32, pages 874-877.
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Ricardo Jorge Dinis-Oliveira, Félix Carvalho, Roxana Moreira, Jorge Brandão Proença, Agostinho Santos, José Alberto Duarte, Maria de Lourdes Bastos & Teresa Magalhães. (2015) Clinical and forensic signs related to chemical burns: A mechanistic approach. Burns 41:4, pages 658-679.
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Xingang Wang, Yuanhai Zhang, Liangfang Ni, Chuangang You, Chunjiang Ye, Ruiming Jiang, Liping Liu, Jia Liu & Chunmao Han. (2014) A review of treatment strategies for hydrofluoric acid burns: Current status and future prospects. Burns 40:8, pages 1447-1457.
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M-L Wu, C-C Yang, J Ger, W-J Tsai & J-F Deng. (2013) Acute hydrofluoric acid exposure reported to Taiwan Poison Control Center, 1991–2010. Human & Experimental Toxicology 33:5, pages 449-454.
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Joo-Yong Na, Kuck-Hyun Woo, Seong-Yong Yoon, Seong-Yong Cho, In-Ung Song, Joo-An Kim & Jin-Seok Kim. (2013) Acute Symptoms after a Community Hydrogen Fluoride Spill. Annals of Occupational and Environmental Medicine 25:1, pages 17.
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Susan Ney Miller. 2013. The Toxicant Induction of Irritant Asthma, Rhinitis, and Related Conditions. The Toxicant Induction of Irritant Asthma, Rhinitis, and Related Conditions 83 101 .
Taiichi Shinzato, Kunihiko Kooguchi, Michihiko Fukui, Masahiro Sakaguchi, Naruhiko Itagaki & Woo Jin Joo. (2011) . Nihon Shuchu Chiryo Igakukai zasshi 18:4, pages 651-652.
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Patrick M. Whiteley & Steven E. Aks. (2010) Case Files of the Toxikon Consortium in Chicago: Survival after Intentional Ingestion of Hydrofluoric Acid. Journal of Medical Toxicology 6:3, pages 349-354.
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