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Case Report

Prolonged severe hypotension following combined amlodipine and valsartan ingestion

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Pages 470-474 | Received 07 Jul 2007, Accepted 31 Oct 2007, Published online: 20 Jan 2009

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Jon B. Cole, Samantha C. Lee, Matthew E. Prekker, Nathan M. Kunzler, Kelly A. Considine, Brian E. Driver, Michael A. Puskarich & Travis D. Olives. (2022) Vasodilation in patients with calcium channel blocker poisoning treated with high-dose insulin: a comparison of amlodipine versus non-dihydropyridines. Clinical Toxicology 60:11, pages 1205-1213.
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Jessica Huang, Nicholas A. Buckley, Katherine Z. Isoardi, Angela L. Chiew, Geoffrey K. Isbister, Rose Cairns, Jared A. Brown & Betty S. Chan. (2021) Angiotensin axis antagonists increase the incidence of haemodynamic instability in dihydropyridine calcium channel blocker poisoning. Clinical Toxicology 59:6, pages 464-471.
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Ludovic Gérard, Anne-Cécile Galloy, Arnaud Capron & Philippe Hantson. (2015) Mixed amlodipine/valsartan overdose treated by the molecular adsorbent recirculating system (MARS™). Clinical Toxicology 53:6, pages 573-577.
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Kristin M. Engebretsen, Kathleen M. Kaczmarek, Jenifer Morgan & Joel S. Holger. (2011) High-dose insulin therapy in beta-blocker and calcium channel-blocker poisoning. Clinical Toxicology 49:4, pages 277-283.
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Articles from other publishers (22)

Abdul Hannan A Rasheed, Kavitha Vellanki, Frank Woo & David J Leehey. (2023) Hyponatremia in a Patient With Vasodilatory Shock Due to Overdose of Antihypertensive Medications: A Case Report. Cureus.
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Lisandra E. de Castro Brás, Cecile L. Baccanale, Lex Eccleston, Trey Sloan, Jason C. St Antoine, Steven Matthew-Lewis Verzwyvelt, Peggy Pittman, Dorcas O'Rourke & William J. Meggs. (2021) Efficacy of methylene blue in a murine model of amlodipine overdose. The American Journal of Emergency Medicine 45, pages 284-289.
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Miho Nakamura, Junya Nakade, Tadashi Toyama, Masaki Okajima & Takumi Taniguchi. (2020) Severe intoxication caused by sodium-glucose cotransporter 2 inhibitor overdose: a case report. BMC Pharmacology and Toxicology 21:1.
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James R. Krenz & Yaman Kaakeh. (2018) An Overview of Hyperinsulinemic-Euglycemic Therapy in Calcium Channel Blocker and β-blocker Overdose. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 38:11, pages 1130-1142.
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Karin E. Reuter-RiceBradley M. Peterson. (2016) Conventional and Unconventional Lifesaving Therapies in an Adolescent With Amlodipine Ingestion. Critical Care Nurse 36:4, pages 64-69.
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Andis Graudins, Hwee Min Lee & Dino Druda. (2015) Calcium channel antagonist and beta‐blocker overdose: antidotes and adjunct therapies. British Journal of Clinical Pharmacology 81:3, pages 453-461.
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JoAn R. Laes, David M. Williams & Jon B. Cole. (2015) Improvement in Hemodynamics After Methylene Blue Administration in Drug-Induced Vasodilatory Shock: A Case Report. Journal of Medical Toxicology 11:4, pages 460-463.
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A. Truhlář, C.D. Deakin, J. Soar, G.E.A. Khalifa, A. Alfonzo, J.J.L.M. Bierens, G. Brattebø, H. Brugger, J. Dunning, S. Hunyadi-Antičević, R.W. Koster, D.J. Lockey, C. Lott, P. Paal, G.D. Perkins, C. Sandroni, K.-C. Thies, D.A. Zideman & J.P. Nolan. (2015) Kreislaufstillstand in besonderen SituationenCardiac arrest in special circumstances. Notfall + Rettungsmedizin 18:8, pages 833-903.
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Anatolij Truhlář, Charles D. Deakin, Jasmeet Soar, Gamal Eldin Abbas Khalifa, Annette Alfonzo, Joost J.L.M. Bierens, Guttorm Brattebø, Hermann Brugger, Joel Dunning, Silvija Hunyadi-Antičević, Rudolph W. Koster, David J. Lockey, Carsten Lott, Peter Paal, Gavin D. Perkins, Claudio Sandroni, Karl-Christian Thies, David A. Zideman, Jerry P. Nolan, Alessandro Barelli, Bernd W. Böttiger, Marios Georgiou, Anthony J. Handley, Thomas Lindner, Mark J. Midwinter, Koenraad G. Monsieurs & Wolfgang A. Wetsch. (2015) European Resuscitation Council Guidelines for Resuscitation 2015. Resuscitation 95, pages 148-201.
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RL Weinberg, NC Bouchard, DC Abrams, M Bacchetta, AL Dzierba, KM Burkart & D Brodie. (2013) Venoarterial extracorporeal membrane oxygenation for the management of massive amlodipine overdose. Perfusion 29:1, pages 53-56.
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Shrinivas Kambali, Raed Alalawi & Kenneth Nugent. (2013) Prolonged Refractory Hypotension Secondary to Amlodipine Overdose. ICU Director 4:3, pages 136-142.
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Shiwan K. Shah, Sanjeev Kumar Goswami, Rajesh V. Babu, Gulshan Sharma & Alexander G. Duarte. (2012) Management of Calcium Channel Antagonist Overdose with Hyperinsulinemia-Euglycemia Therapy: Case Series and Review of the Literature. Case Reports in Critical Care 2012, pages 1-5.
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Melissa L. Givens. (2012) Toxic Bradycardias in the Critically Ill Poisoned Patient. Emergency Medicine International 2012, pages 1-6.
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David H. Jang, Lewis S. Nelson & Robert S. Hoffman. (2011) Methylene Blue in the Treatment of Refractory Shock From an Amlodipine Overdose. Annals of Emergency Medicine 58:6, pages 565-567.
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James O. M. Plumb, Craig Stewart, Michael Eddleston & Thearina de Beer. (2011) Prolonged Refractory Hypotension following Combined Amlodipine and Losartan Ingestion Responsive to Metaraminol. Case Reports in Medicine 2011, pages 1-6.
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Jamie J. Coleman, Anthony R. Cox & Nicholas J. Cowley. 2011. A worldwide yearly survey of new data in adverse drug reactions. A worldwide yearly survey of new data in adverse drug reactions 413 435 .
Terry L. Vanden Hoek, Laurie J. Morrison, Michael Shuster, Michael Donnino, Elizabeth Sinz, Eric J. Lavonas, Farida M. Jeejeebhoy & Andrea Gabrielli. (2010) Part 12: Cardiac Arrest in Special Situations. Circulation 122:18_suppl_3.
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Charles D. Deakin, Laurie J. Morrison, Peter T. Morley, Clifton W. Callaway, Richard E. Kerber, Steven L. Kronick, Eric J. Lavonas, Mark S. Link, Robert W. Neumar, Charles W. Otto, Michael Parr, Michael Shuster, Kjetil Sunde, Mary Ann Peberdy, Wanchun Tang, Terry L. Vanden Hoek, Bernd W. Böttiger, Saul Drajer, Swee Han Lim & Jerry P. Nolan. (2010) Part 8: Advanced life support. Resuscitation 81:1, pages e93-e174.
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Jasmeet Soar, Gavin D. Perkins, Gamal Abbas, Annette Alfonzo, Alessandro Barelli, Joost J.L.M. Bierens, Hermann Brugger, Charles D. Deakin, Joel Dunning, Marios Georgiou, Anthony J. Handley, David J. Lockey, Peter Paal, Claudio Sandroni, Karl-Christian Thies, David A. Zideman & Jerry P. Nolan. (2010) European Resuscitation Council Guidelines for Resuscitation 2010 Section 8. Cardiac arrest in special circumstances: Electrolyte abnormalities, poisoning, drowning, accidental hypothermia, hyperthermia, asthma, anaphylaxis, cardiac surgery, trauma, pregnancy, electrocution. Resuscitation 81:10, pages 1400-1433.
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Tolga Sinan G?ven?Ufuk G?rkan, ?zge G?zelbur?Erkan ?lhan & Servet Altay. (2010) Barnidipine intoxication causing acute myocardial infarction. The American Journal of Emergency Medicine 28:4, pages 541.e1-541.e3.
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