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Cutaneous and Ocular Toxicology Volume 26, 2007 - Issue 3
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Research Article

Evaluation of Barrier Creams Against Sulphur Mustard: (II) In Vivo and In Vitro Studies using the Domestic White Pig

Robert P. Chilcott Chemical Hazards and Poisons Division, Health Protection Agency, Chilton, Didcot, Oxfordshire, United Kingdom
,
Christopher H. Dalton Department of Biomedical Sciences, Dstl Porton Down, Salisbury, Wiltshire, United Kingdom
,
Zoe Ashley Department of Biomedical Sciences, Dstl Porton Down, Salisbury, Wiltshire, United Kingdom
,
Ceri E. Allen Department of Biomedical Sciences, Dstl Porton Down, Salisbury, Wiltshire, United Kingdom
,
Simon T. Bradley Department of Biomedical Sciences, Dstl Porton Down, Salisbury, Wiltshire, United Kingdom
,
Michael P. Maidment Department of Biomedical Sciences, Dstl Porton Down, Salisbury, Wiltshire, United Kingdom
,
John Jenner Department of Biomedical Sciences, Dstl Porton Down, Salisbury, Wiltshire, United Kingdom
,
Roger F. R. Brown Department of Biomedical Sciences, Dstl Porton Down, Salisbury, Wiltshire, United Kingdom
,
Robert J. Gwyther Department of Biomedical Sciences, Dstl Porton Down, Salisbury, Wiltshire, United Kingdom
&
Paul Rice Department of Biomedical Sciences, Dstl Porton Down, Salisbury, Wiltshire, United Kingdom
 show all
Pages 235-247 | Published online: 10 Oct 2008

Citations (23)

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Leila Etemad, Mohammad Moshiri & Mahdi Balali-Mood. (2019) Advances in treatment of acute sulfur mustard poisoning – a critical review. Critical Reviews in Toxicology 49:3, pages 191-214.
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Christopher Dalton, Charlotte Hall, Helen Lydon, John Jenner, J. Kevin Chipman, John S. Graham & Robert P. Chilcott. (2018) The percutaneous absorption of soman in a damaged skin porcine model and the evaluation of WoundStat™ as a topical decontaminant. Cutaneous and Ocular Toxicology 37:2, pages 172-179.
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Robert P. Chilcott, Joanne Larner, Hazem Matar, Sneha Kansagra, Baveetharan Theivendran, Vanessa Anne Viegas & Virginia Streusand Goldman. (2015) Optimisation of a dosing regime for a topical skin protectant (barrier cream). Cutaneous and Ocular Toxicology 34:4, pages 327-334.
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Articles from other publishers (20)

Greta Camilla Magnano, Giovanna Marussi, Matteo Crosera, Dritan Hasa, Gianpiero Adami, Nicola Lionetti & Francesca Larese Filon. (2023) Probing the effectiveness of barrier creams against human skin penetration of nickel powder. International Journal of Cosmetic Science.
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Greta Camilla Magnano, Flavia Carton, Francesca Boccafoschi, Giovanna Marussi, Elisa Cocetta, Matteo Crosera, Gianpiero Adami, Dario Voinovich & Francesca Larese Filon. (2023) Evaluating the role of protective creams on the cutaneous penetration of Ni nanoparticles. Environmental Pollution 328, pages 121654.
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Jeffrey D. Laskin, Kevin Ozkuyumcu, Peihong Zhou, Claire R. Croutch, Diane E. Heck, Debra L. Laskin & Laurie B. Joseph. (2023) Skin Models Used to Define Mechanisms of Action of Sulfur Mustard. Disaster Medicine and Public Health Preparedness 17.
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Jeffrey D. Laskin, Gabriella Wahler, Claire R. Croutch, Patrick J. Sinko, Debra L. Laskin, Diane E. Heck & Laurie B. Joseph. (2020) Skin remodeling and wound healing in the Gottingen minipig following exposure to sulfur mustard. Experimental and Molecular Pathology 115, pages 104470.
Crossref
CD Lindsay & CM Timperley. (2019) TRPA1 and issues relating to animal model selection for extrapolating toxicity data to humans. Human & Experimental Toxicology 39:1, pages 14-36.
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Hazem Matar, Shirley C. Price & Robert P. Chilcott. (2019) Further studies of the efficacy of military, commercial and novel skin decontaminants against the chemical warfare agents sulphur Mustard, Soman and VX. Toxicology in Vitro 54, pages 263-268.
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Maria Valéria Robles Velasco, Rafael Sauce, Camila Areias de Oliveira, Claudinéia A.S. de Oliveira Pinto, Renata Miliani Martinez, Stephanie Baah, Tânia Santos Almeida, Catarina Rosado & André Rolim Baby. (2018) Active ingredients, mechanisms of action and efficacy tests of antipollution cosmetic and personal care products. Brazilian Journal of Pharmaceutical Sciences 54:spe.
Crossref
Charlotte A. Hall, Helen L. Lydon, Christopher H. Dalton, J. Kevin Chipman, John S. Graham & Robert P. Chilcott. (2017) The percutaneous toxicokinetics of Sulphur mustard in a damaged skin porcine model and the evaluation of WoundStat™ as a topical decontaminant. Journal of Applied Toxicology 37:9, pages 1036-1045.
Crossref
Antonella Casiraghi, Francesco Ranzini, Umberto M. Musazzi, Silvia Franzè, Marisa Meloni & Paola Minghetti. (2017) In vitro method to evaluate the barrier properties of medical devices for cutaneous use. Regulatory Toxicology and Pharmacology.
Crossref
Cécile Bignon, Sonia Amigoni, Thierry Devers & Frédéric Guittard. (2017) Barrier cream based on CeO 2 nanoparticles grafted polymer as an active compound against the penetration of organophosphates. Chemico-Biological Interactions 267, pages 17-24.
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Christian Mostosi & Thierry Simonart. (2016) Effectiveness of Barrier Creams against Irritant Contact Dermatitis. Dermatology 232:3, pages 353-362.
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Christopher Dalton, Stuart Graham & John Jenner. (2015) Effect of exposure area on nerve agent absorption through skin in vitro. Toxicology in Vitro 30:1, pages 454-461.
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Christopher H. Dalton, Charlotte A. Hall, Helen L. Lydon, J. K. Chipman, John S. Graham, John Jenner & Robert P. Chilcott. (2015) Development of haemostatic decontaminants for the treatment of wounds contaminated with chemical warfare agents. 2: Evaluation of in vitro topical decontamination efficacy using undamaged skin . Journal of Applied Toxicology 35:5, pages 543-550.
Crossref
Klaus-Peter Wilhelm, Hongbo Zhai & Howard I. MaibachRobert P. Chilcott. 2012. Dermatotoxicology. Dermatotoxicology 144 149 .
F. DorandeuL. Taysse, I. Boudry, A. Foquin, F. Hérodin, J. Mathieu, S. Daulon, C. Cruz & G. Lallement. (2010) Cutaneous challenge with chemical warfare agents in the SKH-1 hairless mouse. (I) Development of a model for screening studies in skin decontamination and protection. Human & Experimental Toxicology 30:6, pages 470-490.
Crossref
Eman Elmahjoubi, Yakov Frum, Gillian M. Eccleston, Simon C. Wilkinson & Victor M. Meidan. (2009) Transepidermal water loss for probing full-thickness skin barrier function: Correlation with tritiated water flux, sensitivity to punctures and diverse surfactant exposures. Toxicology in Vitro 23:7, pages 1429-1435.
Crossref
J. Millerioux, C. Cruz, A. Bazire, G. Lallement, L. Lefeuvre & D. Josse. (2009) In vitro selection and efficacy of topical skin protectants against the nerve agent VX. Toxicology in Vitro 23:3, pages 539-545.
Crossref
J. Millerioux, C. Cruz, A. Bazire, V. Polly, G. Lallement, L. Lefeuvre & D. Josse. (2009) Evaluation of in vitro tests to assess the efficacy of formulations as topical skin protectants against organophosphorus compounds. Toxicology in Vitro 23:1, pages 127-133.
Crossref
Yutaka SHIMAZAKI, Mizuyuki RYU, Yoko YOSHIDA, Yoshihiko HIRATA & Taro FURUTA. (2009) . Japanese Journal of Environmental Infections 24:4, pages 264-270.
Crossref
R. Vijayaraghavan, Anshoo Gautam & Manoj Sharma. 2009. Handbook of Toxicology of Chemical Warfare Agents. Handbook of Toxicology of Chemical Warfare Agents 897 918 .

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