361
Views
69
CrossRef citations to date
0
Altmetric
Original Investigations

Gender-related qualitative differences in baseline and post-stress anxiety responses are not reflected in the incidence of criterion-based PTSD-like behaviour patterns

, , , , & , PhD
Pages 856-869 | Received 27 Dec 2006, Published online: 08 Dec 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Hanna M. Burke, Cristina M. Robinson, Bethany Wentz, Jerel McKay, Kyle W. Dexter, Julia M. Pisansky, Jeffery N. Talbot & Phillip R. Zoladz. (2013) Sex-specific impairment of spatial memory in rats following a reminder of predator stress. Stress 16:4, pages 469-476.
Read now

Articles from other publishers (67)

Sakineh Shafia, Farkhonde Nikkhah & Kobra Akhoundzadeh. (2023) Effect of combination fluoxetine and exercise on prefrontal BDNF, anxiety-like behavior and fear extinction in a female rat model of post-traumatic stress disorder (PTSD): a comparison with male animals. Behavioral and Brain Functions 19:1.
Crossref
H.L. Blount, J. Dee, L. Wu, M. Schwendt & L.A. Knackstedt. (2023) Stress resilience-associated behaviors following predator scent stress are accompanied by upregulated nucleus accumbens mGlu5 transcription in female Sprague Dawley rats. Behavioural Brain Research 436, pages 114090.
Crossref
Mariella B. L. Careaga, Carlos Eduardo Neves Girardi & Deborah Suchecki. 2023. Translational Methods for PTSD Research. Translational Methods for PTSD Research 215 229 .
Arthur A. Coelho, Carla Vila-Verde, Ariandra G. Sartim, Daniela L. Uliana, Laura A. Braga, Francisco S. Guimarães & Sabrina F. Lisboa. (2022) Inducible Nitric Oxide Synthase Inhibition in the Medial Prefrontal Cortex Attenuates the Anxiogenic-Like Effect of Acute Restraint Stress via CB1 Receptors. Frontiers in Psychiatry 13.
Crossref
Qinxi Li, Bangcheng Zhao, Wanxin Li, Yao He, Xun Tang, Ting Zhang, Zhihui Zhong, Qiangwen Pan & Yingqian Zhang. (2022) Effects of repeated drug administration on behaviors in normal mice and fluoxetine efficacy in chronic unpredictable mild stress mice. Biochemical and Biophysical Research Communications 615, pages 36-42.
Crossref
Natália Maria Simionato, Janaína da Silva Rocha-Lopes, Ricardo Borges Machado & Deborah Suchecki. (2022) Chronic rapid eye movement sleep restriction during juvenility has long-term effects on anxiety-like behaviour and neurotransmission of male Wistar rats. Pharmacology Biochemistry and Behavior 217, pages 173410.
Crossref
Xiaofeng Liu, Meiying Song, Xiaowei Chen, Yanfei Sun, Renfei Fan, Liping Wang, Weihong Lin, Zheng Hu & Hua Zhao. (2022) Activation of Estrogen Receptor β in the Lateral Habenula Improves Ovariectomy-Induced Anxiety-Like Behavior in Rats. Frontiers in Behavioral Neuroscience 16.
Crossref
Beatriz Soares-Silva, José Ivo Araújo Beserra-Filho, Pamela Maria Araújo Morera, Ana Claudia Custódio-Silva, Amanda Maria-Macêdo, Suellen Silva-Martins, Vanessa Alexandre-Silva, Sara Pereira Silva, Regina Helena Silva & Alessandra Mussi Ribeiro. (2022) The bee venom active compound melittin protects against bicuculline-induced seizures and hippocampal astrocyte activation in rats. Neuropeptides 91, pages 102209.
Crossref
Silvana Regina de Melo, Lucas B. Gremaschi, Luiz Felipe M.S.B. Blanco, Bárbara M. Orathes, Isabela V.A. Tarosso & Tuany C. Bernardi. (2022) Short Juvenile Stress Has No Long-Lasting Effects on Anxiety-Like Behavior, Object Recognition Memory, or Gross Brain Morphology but Affects Dendritic Spines in the Hippocampus in Male Rats. Developmental Neuroscience 44:6, pages 466-477.
Crossref
Reza Yakhkeshi, Fatemeh Roshani, Kobra Akhoundzadeh & Sakineh Shafia. (2022) Effect of treadmill exercise on serum corticosterone, serum and hippocampal BDNF, hippocampal apoptosis and anxiety behavior in an ovariectomized rat model of post-traumatic stress disorder (PTSD). Physiology & Behavior 243, pages 113629.
Crossref
Marco G.S. Gomes, Saulo G. Tractenberg, Rodrigo Orso, Thiago W. Viola & Rodrigo Grassi-Oliveira. (2022) Sex differences in risk behavior parameters in adolescent mice: Relationship with brain-derived neurotrophic factor in the medial prefrontal cortex. Neuroscience Letters 766, pages 136339.
Crossref
Diulle Spat Peres, Maria Carolina Theisen, Maria Fernanda Pessano Fialho, Diéssica Padilha Dalenogare, Patrícia Rodrigues, Sabrina Qader Kudsi, Laura de Barros Bernardes, Náthaly Andrighetto Ruviaro da Silva, Débora Denardin Lückemeyer, Tuane Bazanella Sampaio, Gabriele Cheiran Pereira, Fernanda Kulinski Mello, Juliano Ferreira, Guilherme Vargas Bochi, Sara Marchesan Oliveira, Caren Tatiane de David Antoniazzi & Gabriela Trevisan. (2021) TRPA1 involvement in depression- and anxiety-like behaviors in a progressive multiple sclerosis model in mice. Brain Research Bulletin 175, pages 1-15.
Crossref
John Shallcross, Lizhen Wu, Courtney S. Wilkinson, Lori A. Knackstedt & Marek Schwendt. (2021) Increased mGlu5 mRNA expression in BLA glutamate neurons facilitates resilience to the long-term effects of a single predator scent stress exposure. Brain Structure and Function 226:7, pages 2279-2293.
Crossref
Natália C. Zanta, Deborah Suchecki & Carlos Eduardo Neves Girardi. (2021) Early life stress alters emotional learning in a sex‐ and age‐dependent manner with no impact on emotional behaviors. Developmental Psychobiology 63:6.
Crossref
Cana B. Quave, Steven J. Nieto, Colin N. Haile & Therese A. Kosten. (2021) Immune receptor toll-like receptor 4 contributes to stress-induced affective responses in a sex-specific manner. Brain, Behavior, & Immunity - Health 14, pages 100248.
Crossref
Lorena Henn, Natália C. Zanta, Carlos Eduardo N. Girardi & Deborah Suchecki. (2020) Chronic Escitalopram Treatment Does Not Alter the Effects of Neonatal Stress on Hippocampal BDNF Levels, 5-HT1A Expression and Emotional Behaviour of Male and Female Adolescent Rats. Molecular Neurobiology 58:3, pages 926-943.
Crossref
Daneele Thorpe, Ryan T. Lacy & Justin C. Strickland. (2020) Acquisition of remifentanil self-administration: Enhanced in female rats but no effect of adolescent stress exposure. Pharmacology Biochemistry and Behavior 199, pages 173038.
Crossref
Silvana Regina de Melo, Caren Tatiane de David Antoniazzi, Shakhawat Hossain & Bryan Kolb. (2020) Short predictable stress promotes resistance to anxiety behavior and increases dendritic spines in prefrontal cortex and hippocampus. Brain Research 1746, pages 147020.
Crossref
Jocelene Filippin Cossetin, Amanda Spring de Almeida, Caren Tatiane de David Antoniazzi, Sabrina Qader Kudsi, Ana Martiele Engelmann, Camille Gaube Guex, Juliana Sorraila de Oliveira, Maria Carolina Theisen, Camila Santos Ritter, Pedro Henrique Doleski, Evelyne da Silva Brum, Diéssica Padilha Dalenogare, Diulle Spat Peres, Francieli Guedes Pintos, Cinthia Melazzo de Andrade, Daniela Bitencourt Rosa Leal, Sara Marchesan Oliveira, Liliane de Freitas Bauermann, Roberta Cougo Riéffel, Michele Rorato Sagrillo, Alencar Kolinski Machado, Adair Roberto Soares Santos & Gabriela Trevisan. (2020) Hydroalcoholic extract of leaf of Arachis hypogaea L. (Fabaceae) did not induce toxic effects in the repeated-dose toxicity study in rats. Regulatory Toxicology and Pharmacology 115, pages 104683.
Crossref
Asli Aykac, Ahmet Özer Şehirli & M. Zafer Gören. (2020) Evaluation of the Effect of Prazosin Treatment on α-2c Adrenoceptor and Apoptosis Protein Levels in the Predator Scent-Induced Rat Model of Post-Traumatic Stress Disorder. Journal of Molecular Neuroscience 70:7, pages 1120-1129.
Crossref
Duttagupta Subhadeep, Bettadapura N. Srikumar, Byrathnahalli S. Shankaranarayana Rao & Bindu M. Kutty. (2020) Short photoperiod restores ventral subicular lesion‐induced deficits in affective and socio‐cognitive behavior in male Wistar rats. Journal of Neuroscience Research 98:6, pages 1114-1136.
Crossref
Sema Ketenci, Nazife Gökçe Acet, Gökçe Elif Sarıdoğan, Banu Aydın, Hülya Cabadak & Mehmet Zafer Gören. (2020) The Neurochemical Effects of Prazosin Treatment on Fear Circuitry in a Rat Traumatic Stress Model. Clinical Psychopharmacology and Neuroscience 18:2, pages 219-230.
Crossref
Alexander Verbitsky, David Dopfel & Nanyin Zhang. (2020) Rodent models of post-traumatic stress disorder: behavioral assessment. Translational Psychiatry 10:1.
Crossref
Lianghui Ni, Yanling Xu, Sixuan Dong, Yujia Kong, Hong Wang, Guohua Lu, Yanyu Wang, Qi Li, Changjiang Li, Zhongde Du, Hongwei Sun & Lin Sun. (2020) The potential role of the HCN1 ion channel and BDNF-mTOR signaling pathways and synaptic transmission in the alleviation of PTSD. Translational Psychiatry 10:1.
Crossref
Aaron M. Kirchhoff, Eric L. Barker & Julia A. Chester. (2019) Endocannabinoids and Fear-Related Behavior in Mice Selectively Bred for High or Low Alcohol Preference. Brain Sciences 9:10, pages 254.
Crossref
Phillip R. Zoladz, Paul A. D'Alessio, Sarah L. Seeley, Charis D. Kasler, Cassandra S. Goodman, Kasey E. Mucher, Alanis S. Allison, Ian F. Smith, Jordan L. Dodson, Thorne S. Stoops & Boyd R. Rorabaugh. (2019) A predator-based psychosocial stress animal model of PTSD in females: Influence of estrous phase and ovarian hormones. Hormones and Behavior 115, pages 104564.
Crossref
Thiago Cagliumi Alves, Eliana Rodrigues, João H.G. Lago, Carla M. Prado, Carlos Eduardo N. Girardi & Debora C. Hipólide. (2019) Petiveria alliacea, a plant used in Afro-Brazilian smoke rituals, triggers pulmonary inflammation in rats. Revista Brasileira de Farmacognosia 29:5, pages 656-664.
Crossref
Dario Aspesi & Graziano Pinna. (2019) Animal models of post-traumatic stress disorder and novel treatment targets. Behavioural Pharmacology 30:2 and 3, pages 130-150.
Crossref
Nataša Popović, Vesna Stojiljković, Snežana Pejić, Ana Todorović, Ivan Pavlović, Ljubica Gavrilović & Snežana B. Pajović. (2019) Modulation of Hippocampal Antioxidant Defense System in Chronically Stressed Rats by Lithium. Oxidative Medicine and Cellular Longevity 2019, pages 1-11.
Crossref
Roxanna J. Nahvi, Chiso Nwokafor, Lidia I. Serova & Esther L. Sabban. (2019) Single Prolonged Stress as a Prospective Model for Posttraumatic Stress Disorder in Females. Frontiers in Behavioral Neuroscience 13.
Crossref
Apryl E. Pooley, Rebecca C. Benjamin, Susheela Sreedhar, Andrew L. Eagle, Alfred J. Robison, Michelle S. Mazei-Robison, S. Marc Breedlove & Cynthia L. Jordan. (2018) Sex differences in the traumatic stress response: PTSD symptoms in women recapitulated in female rats. Biology of Sex Differences 9:1.
Crossref
Alexandra S. Miragaia, Guilherme S. de Oliveira Wertheimer, Amanda C. Consoli, Rafael Cabbia, Beatriz M. Longo, Carlos E. N. Girardi & Deborah Suchecki. (2018) Maternal Deprivation Increases Anxiety- and Depressive-Like Behaviors in an Age-Dependent Fashion and Reduces Neuropeptide Y Expression in the Amygdala and Hippocampus of Male and Female Young Adult Rats. Frontiers in Behavioral Neuroscience 12.
Crossref
Janaína da Silva Rocha-Lopes, Ricardo Borges Machado & Deborah Suchecki. (2017) Chronic REM Sleep Restriction in Juvenile Male Rats Induces Anxiety-Like Behavior and Alters Monoamine Systems in the Amygdala and Hippocampus. Molecular Neurobiology 55:4, pages 2884-2896.
Crossref
Silvana Regina de Melo, Caren Tatiane de David Antoniazzi, Shakhawat Hossain & Bryan Kolb. (2018) Neonatal Stress Has a Long-Lasting Sex-Dependent Effect on Anxiety-Like Behavior and Neuronal Morphology in the Prefrontal Cortex and Hippocampus. Developmental Neuroscience 40:2, pages 93-103.
Crossref
Aslı AYKAC & Buse KARANLIK. (2017) The expression level of muscarinic M1 receptor subtypes in different regions of rat brain. Marmara Medical Journal 30:3, pages 162-168.
Crossref
Jana Tchekalarova, Dimitrinka Atanasova, Zlatina Nenchovska, Milena Atanasova, Lidia Kortenska, Rumyana Gesheva & Nikolai Lazarov. (2017) Agomelatine protects against neuronal damage without preventing epileptogenesis in the kainate model of temporal lobe epilepsy. Neurobiology of Disease 104, pages 1-14.
Crossref
Caren T. D. Antoniazzi, Vinícia G. Metz, Karine Roversi, Daniele L. Freitas, Luciana T. Vey, Verônica T. Dias, Hecson J. Segat, Marta M. M. F. Duarte & Marilise E. Burger. (2017) Tactile stimulation during different developmental periods modifies hippocampal BDNF and GR, affecting memory and behavior in adult rats. Hippocampus 27:2, pages 210-220.
Crossref
Ori Koresh, Zeev Kaplan, Joseph Zohar, Michael A. Matar, Amir B. Geva & Hagit Cohen. (2016) Distinctive cardiac autonomic dysfunction following stress exposure in both sexes in an animal model of PTSD. Behavioural Brain Research 308, pages 128-142.
Crossref
Luciana Taschetto Vey, Higor Zuquetto Rosa, Raquel Cristine Silva Barcelos, Hecson Jesser Segat, Vinícia Garzella Metz, Verônica Tironi Dias, Thiago Duarte, Marta M.M.F. Duarte & Marilise Escobar Burger. (2016) Stress during the gestational period modifies pups’ emotionality parameters and favors preference for morphine in adolescent rats. Behavioural Brain Research 296, pages 408-417.
Crossref
Daniele Freitas, Caren T.D. Antoniazzi, Hecson J. Segat, Vinícia Garzella Metz, Luciana Taschetto Vey, Raquel C.S Barcelos, Thiago Duarte, Marta M.M.F. Duarte & Marilise Escobar Burger. (2015) Neonatal tactile stimulation decreases depression‐like and anxiety‐like behaviors and potentiates sertraline action in young rats. International Journal of Developmental Neuroscience 47:Part_B, pages 192-197.
Crossref
Natasha M. Ivanova, Dimitrina Atanasova, Daniela M. Pechlivanova, Rumyana Mitreva, Nikolai Lazarov, Alexander G. Stoynev & Jana D. Tchekalarova. (2015) Long-term intracerebroventricular infusion of angiotensin II after kainate-induced status epilepticus: Effects on epileptogenesis, brain damage, and diurnal behavioral changes. Epilepsy & Behavior 51, pages 1-12.
Crossref
Daphna Fenchel, Yechiel Levkovitz, Ella Vainer, Zeev Kaplan, Joseph Zohar & Hagit Cohen. (2015) Beyond the HPA-axis: The role of the gonadal steroid hormone receptors in modulating stress-related responses in an animal model of PTSD. European Neuropsychopharmacology 25:6, pages 944-957.
Crossref
Rebecca M. Shansky. (2015) Sex differences in PTSD resilience and susceptibility: Challenges for animal models of fear learning. Neurobiology of Stress 1, pages 60-65.
Crossref
Jana D. Tchekalarova, Natasha M. Ivanova, Daniela M. Pechlivanova, Dimitrina Atanasova, Nikolai Lazarov, Lidia Kortenska, Rumiana Mitreva, Valentin Lozanov & Alexander Stoynev. (2014) Antiepileptogenic and neuroprotective effects of losartan in kainate model of temporal lobe epilepsy. Pharmacology Biochemistry and Behavior 127, pages 27-36.
Crossref
Humberto Gagliano, Roser Nadal & Antonio Armario. (2014) Sex differences in the long-lasting effects of a single exposure to immobilization stress in rats. Hormones and Behavior 66:5, pages 793-801.
Crossref
D Joel & R Yankelevitch-Yahav. (2014) Reconceptualizing sex, brain and psychopathology: interaction, interaction, interaction. British Journal of Pharmacology 171:20, pages 4620-4635.
Crossref
N Kokras & C Dalla. (2014) Sex differences in animal models of psychiatric disorders. British Journal of Pharmacology 171:20, pages 4595-4619.
Crossref
H. Cohen, M. A. Matar & J. Zohar. (2014) Maintaining the Clinical Relevance of Animal Models in Translational Studies of Post-Traumatic Stress Disorder. ILAR Journal 55:2, pages 233-245.
Crossref
M. Danet Lapiz-Bluhm & Alan L. Peterson. 2014. Behavioral Neurobiology of Stress-related Disorders. Behavioral Neurobiology of Stress-related Disorders 161 190 .
Michael A. Matar, Joseph Zohar & Hagit Cohen. (2013) Translationally relevant modeling of PTSD in rodents. Cell and Tissue Research 354:1, pages 127-139.
Crossref
Nikolaos P. Daskalakis, Rachel Yehuda & David M. Diamond. (2013) Animal models in translational studies of PTSD. Psychoneuroendocrinology 38:9, pages 1895-1911.
Crossref
Berna Terzioğlu, Melisa Kaleli, Banu Aydın, Sema Ketenci, Hülya Cabadak & M. Zafer Gören. (2013) Increased Noradrenaline Levels in the Rostral Pons can be Reversed by M1 Antagonist in a Rat Model of Post-traumatic Stress Disorder. Neurochemical Research 38:8, pages 1726-1733.
Crossref
A. Boscolo, C. Ori, J. Bennett, B. Wiltgen & V. Jevtovic-Todorovic. (2013) Mitochondrial protectant pramipexole prevents sex-specific long-term cognitive impairment from early anaesthesia exposure in rats. British Journal of Anaesthesia 110, pages i47-i52.
Crossref
J. SVOBODA, P. TELENSKÝ, K. BLAHNA, J. BUREŠ & A. STUCHLÍK. (2012) Comparison of Male and Female Rats in Avoidance of a Moving Object: More Thigmotaxis, Hypolocomotion and Fear-Like Reactions in Females. Physiological Research, pages 659-663.
Crossref
M. Belviranli, K.E.N. Atalik, N. Okudan & H. Gökbel. (2012) Age and sex affect spatial and emotional behaviors in rats: The role of repeated elevated plus maze test. Neuroscience 227, pages 1-9.
Crossref
Aslı Aykaç, Banu Aydın, Hülya Cabadak & M. Zafer Gören. (2012) The change in muscarinic receptor subtypes in different brain regions of rats treated with fluoxetine or propranolol in a model of post-traumatic stress disorder. Behavioural Brain Research 232:1, pages 124-129.
Crossref
Joy Simpson & John P. Kelly. (2012) An investigation of whether there are sex differences in certain behavioural and neurochemical parameters in the rat. Behavioural Brain Research 229:1, pages 289-300.
Crossref
N. Kozlovsky, J. Zohar, Z. Kaplan & H. Cohen. (2012) Microinfusion of a Corticotrophin-Releasing Hormone Receptor 1 Antisense Oligodeoxynucleotide into the Dorsal Hippocampus Attenuates Stress Responses at Specific Times After Stress Exposure. Journal of Neuroendocrinology 24:3, pages 489-503.
Crossref
Hagit Cohen, Nitsan Kozlovsky, Cramer Alona, Michael A. Matar & Zohar Joseph. (2012) Animal model for PTSD: From clinical concept to translational research. Neuropharmacology 62:2, pages 715-724.
Crossref
Hagit Cohen, Tianmin Liu, Nitsan Kozlovsky, Zeev Kaplan, Joseph Zohar & Aleksander A Mathé. (2011) The Neuropeptide Y (NPY)-ergic System is Associated with Behavioral Resilience to Stress Exposure in an Animal Model of Post-Traumatic Stress Disorder. Neuropsychopharmacology 37:2, pages 350-363.
Crossref
Thu N. Huynh, Amanda M. Krigbaum, Jeffery J. Hanna & Cheryl D. Conrad. (2011) Sex differences and phase of light cycle modify chronic stress effects on anxiety and depressive-like behavior. Behavioural Brain Research 222:1, pages 212-222.
Crossref
Hagit Cohen, Gal Richter‐Levin & Joseph Zohar. 2011. The Handbook of Stress. The Handbook of Stress 388 409 .
Paul G. Green, Pedro Alvarez, Robert W. Gear, Dennis Mendoza & Jon D. Levine. (2011) Further Validation of a Model of Fibromyalgia Syndrome in the Rat. The Journal of Pain 12:7, pages 811-818.
Crossref
Hagit Cohen, Michael A. Matar & Joseph Zohar. 2011. Mood and Anxiety Related Phenotypes in Mice. Mood and Anxiety Related Phenotypes in Mice 185 208 .
Hagit Cohen, Israel Liberzon & Gal Richter-Levin. (2008) Exposure to extreme stress impairs contextual odour discrimination in an animal model of PTSD. The International Journal of Neuropsychopharmacology 12:03, pages 291.
Crossref
Harrison L. Blount, Jason Dee, Lizhen Wu, Marek Schwendt & Lori Knackstedt. (2022) Resilience to Anxiety and Anhedonia after Predator Scent Stress is Accompanied by Increased Nucleus Accumbens mGlu5 in Female Rats. SSRN Electronic Journal.
Crossref
Marco Signor Gomes, Saulo Gantes Tractenberg, Rodrigo Orso, Thiago Wendt Viola & Rodrigo Grassi-Oliveira. (2021) Sex Differences in Risk Behavior Parameters in Adolescent Mice: Relationship with Brain-Derived Neurotrophic Factor in the Medial Prefrontal Cortex. SSRN Electronic Journal.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.