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The World Journal of Biological Psychiatry Volume 10, 2009 - Issue 3
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Review Article

Antidepressants: Controversies about their efficacy in depression, their effect on suicidality and their place in a complex psychiatric treatment approach

Hans-Jürgen Möller Department of Psychiatry, Ludwig-Maximilians-University Munich, Munich, GermanyCorrespondence[email protected]
Pages 180-195 | Received 13 Jan 2009, Published online: 13 Aug 2009

Citations (18)

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Read on this site (3)

Hans-Jürgen Möller. (2017) Why are new antidepressants failing to make the grade for approval?. Expert Opinion on Pharmacotherapy 18:7, pages 641-643.
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Emanuel Severus, Ilya Lipkovich, Florian Seemüller, Michael Obermeier, Heinz Grunze, Britta Bernhard, Sandra Dittmann, Michael Riedel & Hans-Jürgen Möller. (2013) The potential role of Marginal Structural Models (MSMs) in testing the effectiveness of antidepressants in the treatment of patients with major depression in everyday clinical practice. The World Journal of Biological Psychiatry 14:5, pages 386-395.
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Hans-Jürgen Möller. (2011) Effectiveness studies: advantages and disadvantages. Dialogues in Clinical Neuroscience 13:2, pages 199-207.
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Articles from other publishers (15)

Xenia Gonda, Peter Dome, Gianluca Serafini & Maurizio Pompili. (2023) How to save a life: From neurobiological underpinnings to psychopharmacotherapies in the prevention of suicide. Pharmacology & Therapeutics 244, pages 108390.
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Leonardo Tondo & Ross J. Baldessarini. 2021. Ketamine for Treatment-Resistant Depression. Ketamine for Treatment-Resistant Depression 85 115 .
Michael Musker & Ma-Li Wong. 2019. Neurobiology of Depression. Neurobiology of Depression 265 275 .
Leonardo Tondo & Ross J. Baldessarini. (2016) Suicidal Behavior in Mood Disorders: Response to Pharmacological Treatment. Current Psychiatry Reports 18:9.
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Konstantinos N Fountoulakis, Myrto T Samara & Melina Siamouli. (2013) Burning issues in the meta-analysis of pharmaceutical trials for depression. Journal of Psychopharmacology 28:2, pages 106-117.
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Elizabeth CM de Lange. 2014. Applied Pharmacometrics. Applied Pharmacometrics 407 449 .
Siegfried Kasper & Stuart MontgomeryHans‐Jürgen Möller, Florian Seemüller, Rebecca Schennach & Ramesh K. Gupta. 2013. Treatment‐resistant Depression. Treatment‐resistant Depression 21 41 .
Frederick Rohan Walker. (2013) A critical review of the mechanism of action for the selective serotonin reuptake inhibitors: Do these drugs possess anti-inflammatory properties and how relevant is this in the treatment of depression?. Neuropharmacology 67, pages 304-317.
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Konstantinos N Fountoulakis & Hans-Jürgen Möller. (2011) Antidepressant drugs and the response in the placebo group: the real problem lies in our understanding of the issue. Journal of Psychopharmacology 26:5, pages 744-750.
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H.-J. Möller, I. Bitter, J. Bobes, K. Fountoulakis, C. Höschl & S. Kasper. (2020) Position statement of the European Psychiatric Association (EPA) on the value of antidepressants in the treatment of unipolar depression. European Psychiatry 27:2, pages 114-128.
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Michael E. Thase. (2011) The Small Specific Effects of Antidepressants in Clinical Trials: What Do They Mean to Psychiatrists?. Current Psychiatry Reports 13:6, pages 476-482.
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Thomas C. Baghai, Pierre Blier, David S. Baldwin, Michael Bauer, Guy M. Goodwin, Kostas N. Fountoulakis, Siegfried Kasper, Brian E. Leonard, Ulrik F. Malt, Dan Stein, Marcio Versiani & Hans-Jürgen Möller. (2011) General and comparative efficacy and effectiveness of antidepressants in the acute treatment of depressive disorders: a report by the WPA section of pharmacopsychiatry. European Archives of Psychiatry and Clinical Neuroscience 261:S3, pages 207-245.
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Konstantinos N. Fountoulakis & Hans-Jürgen Möller. (2010) Efficacy of antidepressants: a re-analysis and re-interpretation of the Kirsch data. The International Journal of Neuropsychopharmacology 14:03, pages 405-412.
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H.-J. Möller. 2011. Psychiatrie, Psychosomatik, Psychotherapie. Psychiatrie, Psychosomatik, Psychotherapie 1177 1191 .
. (2010) Current awareness: Pharmacoepidemiology and drug safety. Pharmacoepidemiology and Drug Safety 19:2.
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