Advanced search
Publication Cover
Expert Opinion on Drug Delivery Volume 13, 2016 - Issue 10
Submit an article Journal homepage
222
Views
11
CrossRef citations to date
0
Altmetric
Review

Could simvastatin be considered as a potential therapy for chronic lung diseases? A debate on the pros and cons

Alaa S. TulbahRespiratory Technology, Woolcock Institute of Medical Research and Discipline of Pharmacology, Sydney Medical School, Sydney University, Australia;Faculty of Pharmacy, Umm Al Qura University, Makkah, Saudi Arabia
,
Hui Xin OngRespiratory Technology, Woolcock Institute of Medical Research and Discipline of Pharmacology, Sydney Medical School, Sydney University, Australia
,
Paolo ColomboDepartment of Pharmacy, University of Parma, Parma, Italy
,
Paul M. YoungRespiratory Technology, Woolcock Institute of Medical Research and Discipline of Pharmacology, Sydney Medical School, Sydney University, Australia
&
Daniela TrainiRespiratory Technology, Woolcock Institute of Medical Research and Discipline of Pharmacology, Sydney Medical School, Sydney University, AustraliaCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-7173-017X
ORCID Icon
Pages 1407-1420 | Received 03 Feb 2016, Accepted 18 May 2016, Published online: 06 Jun 2016

Citations (11)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Amir A. Zeki & Mona Elbadawi-Sidhu. (2018) Innovations in asthma therapy: is there a role for inhaled statins?. Expert Review of Respiratory Medicine 12:6, pages 461-473.
Read now

Articles from other publishers (10)

Siyuan Zha, Xia Yu, Xiaoxiao Wang, Yan Gu, Yidong Tan, Ying Lu & Zhirong Yao. (2022) Topical Simvastatin Improves Lesions of Diffuse Normolipemic Plane Xanthoma by Inhibiting Foam Cell Pyroptosis. Frontiers in Immunology 13.
Crossref
Xinye Wang, Ran Huo, Zhongjie Liang, Congcong Xu, Tingting Chen, Jingjing Lin, Luyao Li, Wei Lin, Bingting Pan, Xiaoqin Fu & Shangqin Chen. (2022) Simvastatin Inhibits NLRP3 Inflammasome Activation and Ameliorates Lung Injury in Hyperoxia-Induced Bronchopulmonary Dysplasia via the KLF2-Mediated Mechanism. Oxidative Medicine and Cellular Longevity 2022, pages 1-15.
Crossref
Samrad Mehrabi, Jalal Torkan & Massood Hosseinzadeh. (2021) Effect of atorvastatin on serum periostin and blood eosinophils in asthma – a placebo-controlled randomized clinical trial. Journal of International Medical Research 49:12, pages 030006052110637.
Crossref
Alaa S. Tulbah. (2020) The potential of Atorvastatin for chronic lung diseases therapy. Saudi Pharmaceutical Journal 28:11, pages 1353-1363.
Crossref
Sean D. McCarthy, Héctor E. González & Brendan D. Higgins. (2020) Future Trends in Nebulized Therapies for Pulmonary Disease. Journal of Personalized Medicine 10:2, pages 37.
Crossref
Alaa S. Tulbah, Elvira Pisano, Emelie Landh, Santo Scalia, Paul M. Young, Daniela Traini & Hui Xin Ong. (2019) Simvastatin Nanoparticles Reduce Inflammation in LPS-Stimulated Alveolar Macrophages. Journal of Pharmaceutical Sciences 108:12, pages 3890-3897.
Crossref
Wangding Lu, Thomas Rades, Jukka Rantanen, Hak-Kim Chan & Mingshi Yang. (2019) Amino acids as stabilizers for spray-dried simvastatin powder for inhalation. International Journal of Pharmaceutics 572, pages 118724.
Crossref
Ae Ri Kim, Ji-Hye Kim, Aeryun Kim, Yongsung Sohn, Jeong-Heon Cha, Eun-Jung Bak & Yun-Jung Yoo. (2018) Simvastatin attenuates tibial bone loss in rats with type 1 diabetes and periodontitis. Journal of Translational Medicine 16:1.
Crossref
Peta Bradbury, Daniela Traini, Alaina J. Ammit, Paul M. Young & Hui Xin Ong. (2018) Repurposing of statins via inhalation to treat lung inflammatory conditions. Advanced Drug Delivery Reviews 133, pages 93-106.
Crossref
Alaa S Tulbah, Elvira Pisano, Santo Scalia, Paul M Young, Daniela Traini & Hui Xin Ong. (2017) Inhaled simvastatin nanoparticles for inflammatory lung disease. Nanomedicine 12:20, pages 2471-2485.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.