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Review

Potential benefits of chewing gum for the delivery of oral therapeutics and its possible role in oral healthcare

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Pages 1421-1431 | Received 03 Apr 2016, Accepted 17 May 2016, Published online: 03 Jun 2016

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Hongwei Yu, Lei Yu, Xiulei Qi, Jing Cui, Ke Wu, Yide Liu, Long Chen & Xiankai Li. (2023) Versatile chewed gum composites with liquid metal for strain sensing, electromagnetic interference shielding and flexible electronics. Journal of Materials Chemistry C 11:31, pages 10455-10463.
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Yuliia Maslii, Liudmyla Garmanchuk, Olena Ruban, Taisa Dovbynchuk, Nataliia Herbina, Giedre Kasparaviciene & Jurga Bernatoniene. (2023) The Study of the Cytotoxicity, Proliferative and Microbiological Activity of the Medicated Chewing Gum with Ascorbic Acid and Lysozyme Hydrochloride Using Different Culture of Cells. Pharmaceutics 15:7, pages 1894.
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Xuelian Jiang, Yufei Wang, Xinwei Li, Zening Feng, Yuhao Zeng, Sili Han, Nobuhiro Takahashi & Linglin Zhang. (2022) Development and evaluation of a chewing gum containing antimicrobial peptide GH12 for caries prevention. European Journal of Oral Sciences 130:5.
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Melanie Nasseripour, Jonathon Timothy Newton, Fiona Warburton, Oluwatunmise Awojobi, Sonya Di Giorgio, Jennifer Elizabeth Gallagher & Avijit Banerjee. (2022) A Systematic Review and Meta-Analysis of the Role of Sugar-Free Chewing Gum on Plaque Quantity in the Oral Cavity. Frontiers in Oral Health 3.
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Hitoshi Uchida & Catherine E. Ovitt. (2022) Novel impacts of saliva with regard to oral health. The Journal of Prosthetic Dentistry 127:3, pages 383-391.
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Francisco Wilker Mustafa Gomes Muniz, Fabricio Batistin Zanatta, Mariana da Silva Muñoz, Lilia Maia Aguiar, Francisco Hecktheuer Silva & Anelise Fernandes Montagner. (2022) Antiplaque and antigingivitis efficacy of medicated and non-medicated sugar-free chewing gum as adjuncts to toothbrushing: systematic review and network meta-analysis. Clinical Oral Investigations 26:2, pages 1155-1172.
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Khalid M. El-Say & Tarek A. Ahmed. 2022. The ADME Encyclopedia. The ADME Encyclopedia 222 231 .
Amit Saha Roy. (2021) Improper Disposal of Non-biodegradable Chewing Gum is One of the Biggest Threats to Our Ecology: A Review. Current World Environment 16:3, pages 916-927.
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Melanie Nasseripour, Jonathon Timothy Newton, Fiona Warburton, Oluwatunmise Awojobi, Sonya Di Giorgio, Jennifer Elizabeth Gallagher & Avijit Banerjee. (2021) A systematic review and meta-analysis of the role of sugar-free chewing gum on Streptococcus mutans. BMC Oral Health 21:1.
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Arumugam Priya, Anthonymuthu Selvaraj, Dass Divya, Ramalingam Karthik Raja & Shunmugiah Karutha Pandian. (2021) In Vitro and In Vivo Anti-infective Potential of Thymol Against Early Childhood Caries Causing Dual Species Candida albicans and Streptococcus mutans. Frontiers in Pharmacology 12.
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Yuliia Maslii, Tetiana Kolisnyk, Olena Ruban, Olga Yevtifieieva, Svitlana Gureyeva, Andriy Goy, Giedre Kasparaviciene, Zenona Kalveniene & Jurga Bernatoniene. (2021) Impact of Compression Force on Mechanical, Textural, Release and Chewing Perception Properties of Compressible Medicated Chewing Gums. Pharmaceutics 13:11, pages 1808.
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Rahul Singh, Zhi Ren, Yao Shi, Shina Lin, Kwang‐Chul Kwon, Shanmugaraj Balamurugan, Vineeta Rai, Francis Mante, Hyun Koo & Henry Daniell. (2021) Affordable oral health care: dental biofilm disruption using chloroplast made enzymes with chewing gum delivery. Plant Biotechnology Journal 19:10, pages 2113-2125.
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Baochang Cheng & Peiyi Wu. (2021) Recycled Iontronic from Discarded Chewed Gum for Personalized Healthcare Monitoring and Intelligent Information Encryption. ACS Applied Materials & Interfaces 13:5, pages 6731-6738.
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Duncan Parker-Groves. (2021) Should dentists recommend sugar-free chewing gum to help prevent decay?. BDJ Team 8:1, pages 9-9.
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Khalid M. El-Say & Tarek A. Ahmed. 2021. The ADME Encyclopedia. The ADME Encyclopedia 1 10 .
Leila Satari, Alba Guillén, Àngela Vidal-Verdú & Manuel Porcar. (2020) The wasted chewing gum bacteriome. Scientific Reports 10:1.
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Duncan Parker-Groves. (2020) Should dentists recommend sugar-free chewing gum to help prevent decay?. Evidence-Based Dentistry 21:3, pages 88-88.
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J.T. Newton, O. Awojobi, M. Nasseripour, F. Warburton, S. Di Giorgio, J.E. Gallagher & A. Banerjee. (2019) A Systematic Review and Meta-Analysis of the Role of Sugar-Free Chewing Gum in Dental Caries. JDR Clinical & Translational Research 5:3, pages 214-223.
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Shiva Mortazavi, Abolfazl Aslani, Mehrnoush Babaee & Maryam Hajiahmadi. (2019) Persica chewing gum effects on saliva fluoride concentration and flow rate: A triple-blind randomized clinical trial. Contemporary Clinical Dentistry 10:1, pages 117.
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Turki Al Hagbani & Sami Nazzal. (2018) Medicated Chewing Gums (MCGs): Composition, Production, and Mechanical Testing. AAPS PharmSciTech 19:7, pages 2908-2920.
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Pawitra Pulbutr, Sakulrat Rattanakia, Wanwisa Khunawatta, Kritsanee Saramunee & Bunleu Sungthong. (2018) Development of Chewing Gum Containing Mulberry Leaf Extract with Anti-cariogenic Activity against Streptococcus mutans. Journal of Biological Sciences 18:7, pages 407-414.
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Urszula Piotrowska, Marcin Sobczak & Ewa Oledzka. (2017) Current state of a dual behaviour of antimicrobial peptides-Therapeutic agents and promising delivery vectors. Chemical Biology & Drug Design 90:6, pages 1079-1093.
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Stefan W. Wessel, Henny C. van der Mei, Anje M. Slomp, Betsy van de Belt-Gritter, Michael W. J. Dodds & Henk J. Busscher. (2017) Self-perceived mouthfeel and physico-chemical surface effects after chewing gums containing sorbitol and Magnolia bark extract. European Journal of Oral Sciences 125:5, pages 379-384.
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