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Expert Opinion on Drug Metabolism & Toxicology Volume 15, 2019 - Issue 7
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Review

Opioids and the Risk of Infection: A Critical Appraisal of the Pharmacologic and Clinical Evidence

Farzin Khosrow-KhavarDepartment of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada;Centre for Clinical Epidemiology, Lady Davis Institute, Jewish General Hospital, Montreal, QC, CanadaView further author information
,
Siyana KurtevaDepartment of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada;Clinical and Health Informatics Research Group, McGill University, Montreal, QC, CanadaView further author information
,
Ying CuiDepartment of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, CanadaView further author information
,
Kristian B. FilionDepartment of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada;Department of Medicine, McGill University, Montreal, QC, Canada;Centre for Clinical Epidemiology, Lady Davis Institute, Jewish General Hospital, Montreal, QC, CanadaView further author information
&
Antonios DourosDepartment of Medicine, McGill University, Montreal, QC, Canada;Institute of Clinical Pharmacology and Toxicology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany;Centre for Clinical Epidemiology, Lady Davis Institute, Jewish General Hospital, Montreal, QC, CanadaCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-6005-4006View further author information
ORCID Icon
Pages 565-575 | Received 29 Apr 2019, Accepted 17 Jun 2019, Published online: 27 Jun 2019

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Aleksandra Kotlińska-Lemieszek & Zbigniew Żylicz. (2022) Less Well-Known Consequences of the Long-Term Use of Opioid Analgesics: A Comprehensive Literature Review. Drug Design, Development and Therapy 16, pages 251-264.
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Vipula R. Bataduwaarachchi, SMN Hansanie, Neesha Rockwood & Leon Gerard D'Cruz. (2023) Immunomodulatory properties of morphine and the hypothesised role of long-term opioid use in the immunopathogenesis of tuberculosis. Frontiers in Immunology 14.
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John M. Kopriva, Andrew M. Schwartz, Jacob M. Wilson, Jason A. Shah, Kevin X. Farley, Eric R. Wagner & Michael B. Gottschalk. (2023) Tramadol use before total shoulder arthroplasty: patients have lower risk of complications and resource utilization than those using traditional opioids. Journal of Shoulder and Elbow Surgery.
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Joseph Ben Hill, Cy Fixen, Garth Wright & Joseph J. Saseen. (2023) Medications Associated with Occurrence of Urinary Tract Infections in Patients with Diabetes, Heart Failure or Both. Current Drug Safety 18:3, pages 368-373.
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Azamatov Golibkhon, Bazarbaev Akbar Gafur Ugli & Muzaffar Makhamadjonov Farkhod Ugli. (2023) Opioid Agents and Cardiac Arrhythmia: A Literature Review. Cureus.
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Brooke Barlow, Sameer Ponnaluri, Ashley Barlow & William Roth. (2022) Targeting the gut microbiome in the management of sepsis-associated encephalopathy. Frontiers in Neurology 13.
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Yi Du, Haipeng Shi, Xiaojing Yang & Weidong Wu. (2022) Machine learning for infection risk prediction in postoperative patients with non-mechanical ventilation and intravenous neurotargeted drugs. Frontiers in Neurology 13.
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Emma Casely & Helen Laycock. (2022) Opioids in pain medicine. Anaesthesia & Intensive Care Medicine 23:7, pages 384-390.
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Jacob M Wilson, Kevin X Farley, Greg A Erens, Thomas L Bradbury & George N Guild3rd3rd. (2020) Preoperative opioid use is a risk factor for complication following revision total hip arthroplasty. HIP International 32:3, pages 363-370.
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Elizabeth C.S. Swart, Terri V. Newman, Yan Huang, Robert J. Howell, Mei Han, Chester B. Good, Samuel K. Peasah & Natasha Parekh. (2022) Patient and medication‐related factors associated with opioid use disorder after inpatient opioid administration. Journal of Hospital Medicine 17:5, pages 342-349.
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Pamela E Macintyre. (2021) The opioid epidemic from the acute care hospital front line. Anaesthesia and Intensive Care 50:1-2, pages 29-43.
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James Wilton, Stanley Wong, Roy Purssell, Younathan Abdia, Mei Chong, Mohammad Ehsanul Karim, Aaron MacInnes, Sofia R. Bartlett, Rob F. Balshaw, Tara Gomes, Amanda Yu, Maria Alvarez, Richard C. Dart, Mel Krajden, Jane A. Buxton & Naveed Z. Janjua. (2022) Association Between Prescription Opioid Therapy for Noncancer Pain and Hepatitis C Virus Seroconversion. JAMA Network Open 5:1, pages e2143050.
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. 2022. Arzneimitteltherapie in der Palliativmedizin. Arzneimitteltherapie in der Palliativmedizin 511 774 .
Amber N. Edinoff, Leah A. Kaplan, Sami Khan, Murray Petersen, Emily Sauce, Christopher D. Causey, Elyse M. Cornett, Farnad Imani, Omid Moradi Moghadam, Adam M. Kaye & Alan D. Kaye. (2021) Full Opioid Agonists and Tramadol: Pharmacological and Clinical Considerations. Anesthesiology and Pain Medicine 11:4.
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Jane Quinlan, Nicholas Levy, Dileep N. Lobo & Pamela E. Macintyre. (2021) Preoperative opioid use: a modifiable risk factor for poor postoperative outcomes. British Journal of Anaesthesia 127:3, pages 327-331.
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Jacob M. Wilson, Andrew M. Schwartz, Kevin X. Farley, James R. Roberson, Thomas L. Bradbury & George N. Guild. (2021) Preoperative Analgesia, Complications, and Resource Utilization After Total Hip Arthroplasty: Tramadol Is Associated With Less Risk Than Other Preoperative Opioid Medications. The Journal of Arthroplasty 36:1, pages 180-186.
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Cade Shadbolt, Chris Schilling, Maria C. Inacio, J. Haxby Abbott, Yana Pryymachenko, Ross Wilson, Peter F. M. Choong & Michelle M. Dowsey. (2020) Opioid Use and Total Joint Replacement. Current Rheumatology Reports 22:10.
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Jacob M. Wilson, Kevin X. Farley, Thomas L. Bradbury, Greg A. Erens & George N. Guild. (2020) Preoperative opioid use is a risk factor for complication and increased healthcare utilization following revision total knee arthroplasty. The Knee 27:4, pages 1121-1127.
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Michael Silverman, Justin Slater, Racquel Jandoc, Sharon Koivu, Amit X Garg & Matthew A Weir. (2020) Hydromorphone and the risk of infective endocarditis among people who inject drugs: a population-based, retrospective cohort study. The Lancet Infectious Diseases 20:4, pages 487-497.
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Pamela E. Macintyre, Lindy J. Roberts & Christine A. Huxtable. (2019) Management of Opioid-Tolerant Patients with Acute Pain: Approaching the Challenges. Drugs 80:1, pages 9-21.
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Silvia Franchi, Giorgia Moschetti, Giada Amodeo & Paola Sacerdote. (2019) Do All Opioid Drugs Share the Same Immunomodulatory Properties? A Review From Animal and Human Studies. Frontiers in Immunology 10.
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