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Expert Opinion on Drug Metabolism & Toxicology Volume 17, 2021 - Issue 8: Alternatives to Animal Models in Toxicology
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Review

Multi-organ-on-a-chip for pharmacokinetics and toxicokinetic study of drugs

Jong Hwan SungDepartment of Chemical Engineering, Hongik University, Seoul, sejong, Republic of KoreaCorrespondence[email protected]
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Pages 969-986 | Received 14 Jan 2021, Accepted 23 Mar 2021, Published online: 05 Apr 2021

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Nithin R, Ayushi Aggarwal, Anne Boyina Sravani, Pooja Mallya & Shaila Lewis. (2023) Organ-On-A-Chip: An Emerging Research Platform. Organogenesis 19:1.
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Jong Hwan Sung & Jae Jung Kim. (2023) Recent advances in in vitro skin-on-a-chip models for drug testing. Expert Opinion on Drug Metabolism & Toxicology 19:5, pages 249-267.
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Elisa Giovannetti & Godefridus Peters. (2021) Beyond animal models: implementing the 3Rs principles and improving pharmacological studies with new model systems. Expert Opinion on Drug Metabolism & Toxicology 17:8, pages 867-868.
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Articles from other publishers (18)

Jing Liu & Ying Wang. (2023) Advances in organ‐on‐a‐chip for the treatment of cardiovascular diseases. MedComm – Biomaterials and Applications 2:4.
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Chunping Xu, Jin Feng, Hang Sun, Mingli Yan, Qian Yang, Xiaonan Zhou, Jianguang Yang, Fangyan He & Qing Lin. (2023) Pharmacokinetics of 4-Hydroxybenzaldehyde in Normal and Cerebral Ischemia–Reperfusion Injury Rats Based on Microdialysis Technique. European Journal of Drug Metabolism and Pharmacokinetics.
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Laura A. Milton, Matthew S. Viglione, Louis Jun Ye Ong, Gregory P. Nordin & Yi-Chin Toh. (2023) Vat photopolymerization 3D printed microfluidic devices for organ-on-a-chip applications. Lab on a Chip 23:16, pages 3537-3560.
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Naina Sunildutt, Pratibha Parihar, Abdul Rahim Chethikkattuveli Salih, Sang Ho Lee & Kyung Hyun Choi. (2023) Revolutionizing drug development: harnessing the potential of organ-on-chip technology for disease modeling and drug discovery. Frontiers in Pharmacology 14.
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Yucheng An, Yanjie He, Nan Ge, Jintao Guo, Fan Yang & Siyu Sun. (2023) Organoids to Remodel SARS-CoV-2 Research: Updates, Limitations and Perspectives. Aging and disease, pages 0.
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Arisara Phuwajaroanpong, Prapaporn Chaniad, Walaiporn Plirat, Sathianpong Phoopha, Abdi Wira Septama, Arnon Chukaew & Chuchard Punsawad. (2022) Antiplasmodial Properties of Aqueous and Ethanolic Extracts of Ten Herbal Traditional Recipes Used in Thailand against Plasmodium falciparum. Tropical Medicine and Infectious Disease 7:12, pages 417.
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Zhenxu Yang, Xiaochen Liu, Elise M. Cribbin, Alice M. Kim, Jiao Jiao Li & Ken-Tye Yong. (2022) Liver-on-a-chip: Considerations, advances, and beyond. Biomicrofluidics 16:6.
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Baeckkyoung Sung. (2022) In silico modeling of endocrine organ-on-a-chip systems. Mathematical Biosciences 352, pages 108900.
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Tanvir Ahmed. (2022) Organ-on-a-chip microengineering for bio-mimicking disease models and revolutionizing drug discovery. Biosensors and Bioelectronics: X 11, pages 100194.
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Ivan Rusyn, Courtney Sakolish, Yuki Kato, Clifford Stephan, Leoncio Vergara, Philip Hewitt, Vasanthi Bhaskaran, Myrtle Davis, Rhiannon N Hardwick, Stephen S Ferguson, Jason P Stanko, Piyush Bajaj, Karissa Adkins, Nisha S Sipes, E Sidney Hunter3rd3rd, Maria T Baltazar, Paul L Carmichael, Kritika Sadh & Richard A Becker. (2022) Microphysiological Systems Evaluation: Experience of TEX-VAL Tissue Chip Testing Consortium. Toxicological Sciences 188:2, pages 143-152.
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Louise Miny, Benoît G. C. Maisonneuve, Isabelle Quadrio & Thibault Honegger. (2022) Modeling Neurodegenerative Diseases Using In Vitro Compartmentalized Microfluidic Devices. Frontiers in Bioengineering and Biotechnology 10.
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Lina Lin, Xiaocheng Wang, Mengying Niu, Qiaolin Wu, Huan Wang, Yan Zu & Weijian Wang. (2022) Biomimetic epithelium/endothelium on chips. Engineered Regeneration 3:2, pages 201-216.
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Yi Xiang, Kathleen Miller, Jiaao Guan, Wisarut Kiratitanaporn, Min Tang & Shaochen Chen. (2022) 3D bioprinting of complex tissues in vitro: state-of-the-art and future perspectives. Archives of Toxicology 96:3, pages 691-710.
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JONG HWAN SUNG. (2022) From organ-on-a-chip towards body-on-a-chip. BIOCELL 46:5, pages 1177-1180.
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A. Arathi, X. Joseph, K. B. Megha, V. Akhil & P. V. Mohanan. 2022. Microfluidics and Multi Organs on Chip. Microfluidics and Multi Organs on Chip 199 218 .
Min-Hyeok Kim, Danny van Noort, Jong Hwan Sung & Sungsu Park. (2021) Organ-on-a-Chip for Studying Gut-Brain Interaction Mediated by Extracellular Vesicles in the Gut Microenvironment. International Journal of Molecular Sciences 22:24, pages 13513.
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Guya Diletta Marconi, Cristina Porcheri, Oriana Trubiani & Thimios A. Mitsiadis. (2021) Three-Dimensional Culture Systems for Dissecting Notch Signalling in Health and Disease. International Journal of Molecular Sciences 22:22, pages 12473.
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Min-Hyeok Kim, Donghyun Kim & Jong Hwan Sung. (2021) A Gut-Brain Axis-on-a-Chip for studying transport across epithelial and endothelial barriers. Journal of Industrial and Engineering Chemistry 101, pages 126-134.
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