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Expert Opinion on Drug Metabolism & Toxicology Volume 18, 2022 - Issue 7-8
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Review

Pharmacokinetic and toxicodynamic concepts in idiosyncratic, drug-induced liver injury

Robert A. Rotha Department of Pharmacology and Toxicology and Institute for Integrative Toxicology, Michigan State University, East Lansing, MI, USA;b ProbiTox LLC, Chapel Hill, NC, USACorrespondence[email protected]
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Omar Kanaa Department of Pharmacology and Toxicology and Institute for Integrative Toxicology, Michigan State University, East Lansing, MI, USA;c Institute for Quantitative Health Science & Engineering, Michigan State University, East Lansing, MI, USAView further author information
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David Filipovicc Institute for Quantitative Health Science & Engineering, Michigan State University, East Lansing, MI, USA;d Department of Biomedical Engineering, Michigan State University, East Lansing, MI, USA;e Department of Computational Mathematics, Science and Engineering, Michigan State University, East Lansing, MI, USAView further author information
&
Patricia E. Ganeya Department of Pharmacology and Toxicology and Institute for Integrative Toxicology, Michigan State University, East Lansing, MI, USA;b ProbiTox LLC, Chapel Hill, NC, USAView further author information
Pages 469-481 | Received 04 Mar 2022, Accepted 11 Aug 2022, Published online: 24 Aug 2022

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