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Nanotoxicology Volume 11, 2017 - Issue 7
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Original Article

Nanoparticle size-specific actin rearrangement and barrier dysfunction of endothelial cells

Yizhong LiuDepartment of Biomedical Engineering, Binghamton University, Binghamton, NY, USA; ORCID Iconhttp://orcid.org/0000-0003-3335-5628
ORCID Icon,
Noga RogelDepartment of Neuroscience, Binghamton University, Binghamton, NY, USA
,
Kei HaradaDepartment of Biomedical Engineering, Binghamton University, Binghamton, NY, USA;
,
Leigha JarettDepartment of Biomedical Engineering, Binghamton University, Binghamton, NY, USA;
,
Christopher H. MaioranaDepartment of Biomedical Engineering, Binghamton University, Binghamton, NY, USA;
,
Guy K. GermanDepartment of Biomedical Engineering, Binghamton University, Binghamton, NY, USA; ORCID Iconhttp://orcid.org/0000-0003-2872-4775
ORCID Icon,
Gretchen J. MahlerDepartment of Biomedical Engineering, Binghamton University, Binghamton, NY, USA; ORCID Iconhttp://orcid.org/0000-0002-7286-8920
ORCID Icon &
Amber L. DoironDepartment of Biomedical Engineering, Binghamton University, Binghamton, NY, USA; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-6963-0989
ORCID Icon show all
Pages 846-856 | Received 24 Jan 2017, Accepted 18 Aug 2017, Published online: 08 Sep 2017

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Maria Enea, Miguel Peixoto de Almeida, Peter Eaton, Diana Dias da Silva, Eulália Pereira, Maria Elisa Soares, Maria de Lourdes Bastos & Helena Carmo. (2019) A multiparametric study of gold nanoparticles cytotoxicity, internalization and permeability using an in vitro model of blood–brain barrier. Influence of size, shape and capping agent. Nanotoxicology 13:7, pages 990-1004.
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Zhongyuan Guo, Nicole J. Martucci, Yizhong Liu, Eusoo Yoo, Elad Tako & Gretchen J. Mahler. (2018) Silicon dioxide nanoparticle exposure affects small intestine function in an in vitro model. Nanotoxicology 12:5, pages 485-508.
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Ryan D. Hunt, Omid Sedighi, Wayne M. Clark, Amber L. Doiron & Marilyn J. Cipolla. (2023) Differential effect of gold nanoparticles on cerebrovascular function and biomechanical properties. Physiological Reports 11:16.
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Magdalena Lasak & Karol Ciepluch. (2023) Overview of mechanism and consequences of endothelial leakiness caused by metal and polymeric nanoparticles. Beilstein Journal of Nanotechnology 14, pages 329-338.
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Jiayan Chen, Weiwei Huan, Lijuan Mao, Meiling Huang, Yiqu Wu, Shulin Zhuang & Shixuan Cui. (2023) Impaired barrier integrity of endothelial cells induced by PEGylated black phosphorus nanosheets. Science of The Total Environment 861, pages 160645.
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Junrong Wu, Zhenjun Zhu, Wenjing Liu, Yanli Zhang, Yiyuan Kang, Jia Liu, Chen Hu, Ruolan Wang, Manjin Zhang, Lili Chen & Longquan Shao. (2022) How Nanoparticles Open the Paracellular Route of Biological Barriers: Mechanisms, Applications, and Prospects. ACS Nano 16:10, pages 15627-15652.
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Nengyi Ni, Weiyi Wang, Yu Sun, Xiao Sun & David Tai Leong. (2022) Inducible endothelial leakiness in nanotherapeutic applications. Biomaterials 287, pages 121640.
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Daysi M Diaz-Diestra, Teresa Palacios-Hernandez, Yizhong Liu, Diane E Smith, Alexander K Nguyen, Todor Todorov, Patrick J Gray, Jiwen Zheng, Shelby A Skoog & Peter L Goering. (2022) Impact of Surface Chemistry of Ultrasmall Superparamagnetic Iron Oxide Nanoparticles on Protein Corona Formation and Endothelial Cell Uptake, Toxicity, and Barrier Function. Toxicological Sciences 188:2, pages 261-275.
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Zhihui Wang & Meng Tang. (2020) Research progress on toxicity, function, and mechanism of metal oxide nanoparticles on vascular endothelial cells. Journal of Applied Toxicology 41:5, pages 683-700.
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Yanli Zhang, Yulin Zhang, Junrong Wu, Jia Liu, Yiyuan Kang, Chen Hu, Xiaoli Feng, Wenjing Liu, Haiyun Luo, Aijie Chen, Lili Chen & Longquan Shao. (2021) Effects of carbon-based nanomaterials on vascular endothelia under physiological and pathological conditions: interactions, mechanisms and potential therapeutic applications. Journal of Controlled Release 330, pages 945-962.
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Whitney E. Sinclair, Huei-Huei Chang, Arkaprava Dan, Paul J. A. Kenis, Catherine J. Murphy & Deborah E. Leckband. (2020) Gold nanoparticles disrupt actin organization and pulmonary endothelial barriers. Scientific Reports 10:1.
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Frederick A. JakobiecMehenaz HanbazazhPaula Cortes BarrantesJames Chodosh. (2019) Adult Primary Capillary Hemangioma of the Sclera: A Previously Undescribed Entity With a Review of Epibulbar Vascular Lesions. Ophthalmic Plastic & Reconstructive Surgery 36:4, pages 327-333.
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Blakely B O’Connor, Thomas Grevesse, John F Zimmerman, Herdeline Ann M Ardoña, Jorge A Jimenez, Dimitrios Bitounis, Philip Demokritou & Kevin Kit Parker. (2020) Human brain microvascular endothelial cell pairs model tissue-level blood–brain barrier function. Integrative Biology 12:3, pages 64-79.
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Tong Zhang, Matthew J. Gaffrey, Wei-Jun Qian & Brian D. Thrall. 2020. Interaction of Nanomaterials with the Immune System. Interaction of Nanomaterials with the Immune System 127 148 .
Jaspreet Singh Nagi, Kenneth Skorenko, William Bernier, Wayne E. Jones & Amber L. Doiron. (2019) Near Infrared-Activated Dye-Linked ZnO Nanoparticles Release Reactive Oxygen Species for Potential Use in Photodynamic Therapy. Materials 13:1, pages 17.
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Xianqiang Li, Yuanfang Tang, Chunying Chen, Dexin Qiu & Yi Cao. (2019) PEGylated gold nanorods are not cytotoxic to human endothelial cells but affect kruppel-like factor signaling pathway. Toxicology and Applied Pharmacology 382, pages 114758.
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Jie Kai Tee, Li Xian Yip, Eveline Sheau Tan, Supawan Santitewagun, Arun Prasath, Pu Chun Ke, Han Kiat Ho & David Tai Leong. (2019) Nanoparticles' interactions with vasculature in diseases. Chemical Society Reviews 48:21, pages 5381-5407.
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Feyisayo Eweje, Herdeline Ann M. Ardoña, John F. Zimmerman, Blakely B. O'Connor, Seungkuk Ahn, Thomas Grevesse, Karla N. Rivera, Dimitrios Bitounis, Philip Demokritou & Kevin Kit Parker. (2019) Quantifying the effects of engineered nanomaterials on endothelial cell architecture and vascular barrier integrity using a cell pair model. Nanoscale 11:38, pages 17878-17893.
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Shachi P Vyas & Ritobrata Goswami. (2019) Size-dependent cellular uptake and TLR4 attenuation by gold nanoparticles in lung adenocarcinoma cells. Nanomedicine 14:3, pages 229-253.
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Vladimir Mulens-Arias, Alice Balfourier, Alba Nicolás-Boluda, Florent Carn & Florence Gazeau. (2019) Disturbance of adhesomes by gold nanoparticles reveals a size- and cell type-bias. Biomaterials Science 7:1, pages 389-408.
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Jie Tee, Li Ng, Hannah Koh, David Leong & Han Ho. (2018) Titanium Dioxide Nanoparticles Enhance Leakiness and Drug Permeability in Primary Human Hepatic Sinusoidal Endothelial Cells. International Journal of Molecular Sciences 20:1, pages 35.
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Yizhong Liu, Eunsoo Yoo, Chendong Han, Gretchen J. Mahler & Amber L. Doiron. (2018) Endothelial barrier dysfunction induced by nanoparticle exposure through actin remodeling via caveolae/raft-regulated calcium signalling. NanoImpact 11, pages 82-91.
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Valentina Francia, Aldy Aliyandi & Anna Salvati. (2018) Effect of the development of a cell barrier on nanoparticle uptake in endothelial cells. Nanoscale 10:35, pages 16645-16656.
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