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Nanotoxicology Volume 1, 2007 - Issue 2
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Original

Enzyme-based intravascular defense against organophosphorus neurotoxins: Synergism of dendritic-enzyme complexes with 2-PAM and atropine

I. Petrikovics Department of Chemistry, Sam Houston State University, Huntsville, Texas
, PhD,
M. E. Wales Department of Biophysics and Biochemistry, Texas A&M University, College Station
,
J. C. Jaszberenyi Technical University of Technology and Economics, Budapest
,
M. Budai Department of Pharmaceutics, Semmelweis University, Budapest, Hungary
,
S. I. Baskin Aberdeen Proving Ground, U. S. Army Medical Research Institute of Chemical Defense, , Maryland, , USA
,
M. Szilasi University Medical School, Debrecen, Hungary
,
B. A. Logue Department of Chemistry and Biochemistry, South Dakota State University, , Brookings, South Dakota, USA
,
Patricia Chapela Department of Chemistry, Sam Houston State University, Huntsville, Texas
&
J. R. Wild Department of Biophysics and Biochemistry, Texas A&M University, College Station
 show all
Pages 85-92 | Published online: 10 Jul 2009

Citations (12)

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Ilona Petrikovics, Steven I. Baskin, Keith M. Beigel, Benjamin J. Schapiro, Gary A. Rockwood, Ananda B. W. Manage, Marianna Budai & Maria Szilasi. (2010) Nano-intercalated rhodanese in cyanide antagonism. Nanotoxicology 4:2, pages 247-254.
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Articles from other publishers (11)

Laetitia Poirier, Pauline Jacquet, Laure Plener, Patrick Masson, David Daudé & Eric Chabrière. (2018) Organophosphorus poisoning in animals and enzymatic antidotes. Environmental Science and Pollution Research 28:20, pages 25081-25106.
Crossref
P. Jacquet, L. Poirier, D. Daudé & E. Chabrière. (2019) Intoxication aux organophosphorés : vers des traitements enzymatiques. Annales Pharmaceutiques Françaises 77:5, pages 349-362.
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Dandan Li, Yunze Zhang, Haitao Song, Liangqiu Lu, Deli Liu & Yongze Yuan. (2017) Aminoalcohol-Induced Activation of Organophosphorus Hydrolase (OPH) towards Diisopropylfluorophosphate (DFP). PLOS ONE 12:1, pages e0169937.
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Yang Liu, Jie Li & Yunfeng Lu. (2015) Enzyme therapeutics for systemic detoxification. Advanced Drug Delivery Reviews 90, pages 24-39.
Crossref
Vincent ForsterJean-Christophe Leroux. (2015) Nano-antidotes for drug overdose and poisoning. Science Translational Medicine 7:290.
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Mária Szilasi, Marianna Budai, Lívia Budai & Ilona Petrikovics. (2011) Nanoencapsulated and microencapsulated enzymes in drug antidotal therapy. Toxicology and Industrial Health 28:6, pages 522-531.
Crossref
Ilona Petrikovics, Melinda Wales, Marianna Budai, Jorn C. C. Yu & Mária Szilasi. (2011) Nano-Intercalated Organophosphorus-Hydrolyzing Enzymes in Organophosphorus Antagonism. AAPS PharmSciTech 13:1, pages 112-117.
Crossref
Melinda E. Wales & Tony E. Reeves. (2012) Organophosphorus hydrolase as an in vivo catalytic nerve agent bioscavenger. Drug Testing and Analysis 4:3-4, pages 271-281.
Crossref
R. J. Kernchen. 2011. Biodefence. Biodefence 135 145 .
Rupa S Iyer & William E Fitzgibbon. (2009) Building the future biotechnology workforce: A University of Houston model. Journal of Commercial Biotechnology 15:2, pages 171-182.
Crossref
R.J. Kern, M.E. Wales, E. Tiffany-Castiglioni & J.R. Wild. 2009. Handbook of Toxicology of Chemical Warfare Agents. Handbook of Toxicology of Chemical Warfare Agents 1041 1051 .

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