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Original Articles

Pyrrolizidine alkaloids in food: a spectrum of potential health consequences

, , &
Pages 308-324 | Received 29 Apr 2010, Accepted 06 Dec 2010, Published online: 25 Feb 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (23)

Thiago Bousquet Bandini & Bernardete Ferraz Spisso. (2022) Detection, dietary exposure assessment and risk evaluation of quinolones and pyrrolizidine alkaloids in commercial honey from Brazil. Food Additives & Contaminants: Part B 15:2, pages 89-97.
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Yao Lu, Ka Yan Wong, Chunlai Tan, Jiang Ma, Bo Feng & Ge Lin. (2020) Establishment of a novel CYP3A4-transduced human hepatic sinusoidal endothelial cell model and its application in screening hepatotoxicity of pyrrolizidine alkaloids. Journal of Environmental Science and Health, Part C 38:2, pages 169-185.
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Ewelina Kowalczyk & Krzysztof Kwiatek. (2020) Application of the sum parameter method for the determination of pyrrolizidine alkaloids in teas. Food Additives & Contaminants: Part A 37:4, pages 622-633.
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Christoph Gottschalk, Johannes Ostertag, Karsten Meyer, Klaus Gehring, Stefan Thyssen & Manfred Gareis. (2018) Influence of grass pellet production on pyrrolizidine alkaloids occurring in Senecio aquaticus-infested grassland. Food Additives & Contaminants: Part A 35:4, pages 751-760.
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Christina Kast, Verena Kilchenmann, Hans Reinhard, Benoit Droz, Matteo Angelo Lucchetti, Arne Dübecke, Gudrun Beckh & Otmar Zoller. (2018) Chemical fingerprinting identifies Echium vulgare, Eupatorium cannabinum and Senecio spp. as plant species mainly responsible for pyrrolizidine alkaloids in bee-collected pollen. Food Additives & Contaminants: Part A 35:2, pages 316-327.
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Adriane Alexandre Machado De-Melo, Ligia Bicudo de Almeida-Muradian, María Teresa Sancho & Ana Pascual-Maté. (2018) Composition and properties of Apis mellifera honey: A review. Journal of Apicultural Research 57:1, pages 5-37.
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Emmanuel Letsyo, Gerold Jerz, Peter Winterhalter, Arne Dübecke, Werner von der Ohe, Katharina von der Ohe & Till Beuerle. (2017) Pyrrolizidine alkaloids in floral honeys of tropical Ghana: a health risk assessment. Food Additives & Contaminants: Part B 10:4, pages 300-310.
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Na Li, Fan Zhang, Wei Lian, Huali Wang, Jiang Zheng & Ge Lin. (2017) Immunoassay approach for diagnosis of exposure to pyrrolizidine alkaloids. Journal of Environmental Science and Health, Part C 35:3, pages 127-139.
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Ewelina Kowalczyk & Krzysztof Kwiatek. (2017) Determination of pyrrolizidine alkaloids in selected feed materials with gas chromatography-mass spectrometry. Food Additives & Contaminants: Part A 34:5, pages 853-863.
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Patrick P. J. Mulder, Susannah L. de Witte, Geert M. Stoopen, Jan van der Meulen, Piet G. van Wikselaar, Erik Gruys, Maria J. Groot & Ron L. A. P. Hoogenboom. (2016) Transfer of pyrrolizidine alkaloids from various herbs to eggs and meat in laying hens. Food Additives & Contaminants: Part A 33:12, pages 1826-1839.
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A. Eller & R. Chizzola. (2016) Seasonal variability in pyrrolizidine alkaloids in Senecio inaequidens from the Val Venosta (Northern Italy). Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology 150:6, pages 1306-1312.
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Annahita Rezaie, Seyed Mohammad Mousavi & Mahshid Bagherzadeh Ansari. (2016) Rhabdomyosarcoma in a Silver Carp. Journal of Aquatic Animal Health 28:2, pages 118-121.
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Hong Gao, Jianqing Q Ruan, Jie Chen, Na Li, Changqiang Q Ke, Yang Ye, Ge Lin & Jiyao Y Wang. (2015) Blood pyrrole-protein adducts as a diagnostic and prognostic index in pyrrolizidine alkaloid-hepatic sinusoidal obstruction syndrome. Drug Design, Development and Therapy 9, pages 4861-4868.
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Elizabeth M. Mudge, A. Maxwell P. Jones & Paula N. Brown. (2015) Quantification of pyrrolizidine alkaloids in North American plants and honey by LC-MS: single laboratory validation. Food Additives & Contaminants: Part A 32:12, pages 2068-2074.
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Jianqing Ruan, Hong Gao, Na Li, Junyi Xue, Jie Chen, Changqiang Ke, Yang Ye, Peter Pi-Cheng Fu, Jiang Zheng, Jiyao Wang & Ge Lin. (2015) Blood Pyrrole-Protein Adducts—A Biomarker of Pyrrolizidine Alkaloid-Induced Liver Injury in Humans. Journal of Environmental Science and Health, Part C 33:4, pages 404-421.
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Caroline T. Griffin, Francesca Gosetto, Martin Danaher, Stefano Sabatini & Ambrose Furey. (2014) Investigation of targeted pyrrolizidine alkaloids in traditional Chinese medicines and selected herbal teas sourced in Ireland using LC-ESI-MS/MS. Food Additives & Contaminants: Part A 31:5, pages 940-961.
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Christina Kast, Arne Dübecke, Verena Kilchenmann, Katharina Bieri, Michael Böhlen, Otmar Zoller, Gudrun Beckh & Cord Lüllmann. (2014) Analysis of Swiss honeys for pyrrolizidine alkaloids. Journal of Apicultural Research 53:1, pages 75-83.
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F.J. Orantes-Bermejo, J. Serra Bonvehí, A. Gómez-Pajuelo, M. Megías & C. Torres. (2013) Pyrrolizidine alkaloids: their occurrence in Spanish honey collected from purple viper’s bugloss (Echium spp.). Food Additives & Contaminants: Part A 30:10, pages 1799-1806.
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Anita Varga & Birgit Puschner. (2012) Retrospective study of cattle poisonings in California: recognition, diagnosis, and treatment. Veterinary Medicine: Research and Reports 3, pages 111-127.
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Michael Boppré. (2011) The ecological context of pyrrolizidine alkaloids in food, feed and forage: an overview. Food Additives & Contaminants: Part A 28:3, pages 260-281.
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R.J. Molyneux, D.L. Gardner, S.M. Colegate & J.A. Edgar. (2011) Pyrrolizidine alkaloid toxicity in livestock: a paradigm for human poisoning?. Food Additives & Contaminants: Part A 28:3, pages 293-307.
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A. Dübecke, G. Beckh & C. Lüllmann. (2011) Pyrrolizidine alkaloids in honey and bee pollen. Food Additives & Contaminants: Part A 28:3, pages 348-358.
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